LeishMANIAdb
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C2H2-type domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
C2H2-type domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4H395_LEIBR
TriTrypDb:
LbrM.01.0760 , LBRM2903_010014000 *
Length:
415

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H395
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H395

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 192 196 PF00656 0.481
CLV_C14_Caspase3-7 274 278 PF00656 0.735
CLV_C14_Caspase3-7 40 44 PF00656 0.535
CLV_NRD_NRD_1 130 132 PF00675 0.536
CLV_NRD_NRD_1 298 300 PF00675 0.554
CLV_NRD_NRD_1 63 65 PF00675 0.797
CLV_NRD_NRD_1 77 79 PF00675 0.538
CLV_PCSK_FUR_1 296 300 PF00082 0.551
CLV_PCSK_KEX2_1 130 132 PF00082 0.553
CLV_PCSK_KEX2_1 298 300 PF00082 0.554
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1HS86 Leptomonas seymouri 47% 95%
A0A3S7WNL4 Leishmania donovani 72% 85%
A4HRK3 Leishmania infantum 72% 85%
E9AC71 Leishmania major 69% 100%
E9AJG6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 66% 88%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS