LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4H377_LEIBR
TriTrypDb:
LbrM.01.0570 , LBRM2903_010010900 *
Length:
709

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H377
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H377

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 213 217 PF00656 0.631
CLV_C14_Caspase3-7 596 600 PF00656 0.853
CLV_C14_Caspase3-7 680 684 PF00656 0.527
CLV_NRD_NRD_1 104 106 PF00675 0.606
CLV_NRD_NRD_1 144 146 PF00675 0.783
CLV_NRD_NRD_1 16 18 PF00675 0.744
CLV_NRD_NRD_1 160 162 PF00675 0.502
CLV_NRD_NRD_1 181 183 PF00675 0.717
CLV_NRD_NRD_1 211 213 PF00675 0.731
CLV_NRD_NRD_1 35 37 PF00675 0.428
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3S5H4V8 Leishmania donovani 62% 100%
A4HRH7 Leishmania infantum 62% 100%
E9AC45 Leishmania major 58% 91%
E9AJE1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 57% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS