40S ribosomal protein S7

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ribosomal protein S7, putative

Species:

Leishmania braziliensis

UniProt:

A4H367_LEIBR

TriTrypDb:

LbrM.01.0460 , LBRM2903_010009300

Length:

242

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 4
Forrest at al. (procyclic)	no	yes: 4
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 12

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 10

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005840	ribosome	5	11
GO:0032991	protein-containing complex	1	12
GO:0043226	organelle	2	11
GO:0043228	non-membrane-bounded organelle	3	11
GO:0043229	intracellular organelle	3	11
GO:0043232	intracellular non-membrane-bounded organelle	4	11
GO:0110165	cellular anatomical entity	1	12
GO:1990904	ribonucleoprotein complex	2	12
GO:0005737	cytoplasm	2	1
GO:0015935	small ribosomal subunit	4	1
GO:0022627	cytosolic small ribosomal subunit	5	1
GO:0030684	preribosome	3	1
GO:0032040	small-subunit processome	4	1
GO:0044391	ribosomal subunit	3	1

Expansion

Sequence features

A4H367

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H367

PDB structure(s): 6az1_I

Function

Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	12
GO:0006518	peptide metabolic process	4	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009058	biosynthetic process	2	12
GO:0009059	macromolecule biosynthetic process	4	12
GO:0009987	cellular process	1	12
GO:0019538	protein metabolic process	3	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	12
GO:0043043	peptide biosynthetic process	5	12
GO:0043170	macromolecule metabolic process	3	12
GO:0043603	amide metabolic process	3	12
GO:0043604	amide biosynthetic process	4	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044249	cellular biosynthetic process	3	12
GO:0044260	obsolete cellular macromolecule metabolic process	3	12
GO:0044271	cellular nitrogen compound biosynthetic process	4	12
GO:0071704	organic substance metabolic process	2	12
GO:1901564	organonitrogen compound metabolic process	3	12
GO:1901566	organonitrogen compound biosynthetic process	4	12
GO:1901576	organic substance biosynthetic process	3	12
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006364	rRNA processing	8	1
GO:0006396	RNA processing	6	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0016070	RNA metabolic process	5	1
GO:0016072	rRNA metabolic process	7	1
GO:0022613	ribonucleoprotein complex biogenesis	4	1
GO:0034470	ncRNA processing	7	1
GO:0034660	ncRNA metabolic process	6	1
GO:0042274	ribosomal small subunit biogenesis	5	1
GO:0044085	cellular component biogenesis	3	1
GO:0046483	heterocycle metabolic process	3	1
GO:0071840	cellular component organization or biogenesis	2	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	12
GO:0005198	structural molecule activity	1	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	116	118	PF00675	0.265
CLV_NRD_NRD_1	141	143	PF00675	0.226
CLV_NRD_NRD_1	183	185	PF00675	0.244
CLV_NRD_NRD_1	203	205	PF00675	0.251
CLV_NRD_NRD_1	224	226	PF00675	0.332
CLV_NRD_NRD_1	47	49	PF00675	0.380
CLV_NRD_NRD_1	50	52	PF00675	0.238
CLV_PCSK_KEX2_1	129	131	PF00082	0.253
CLV_PCSK_KEX2_1	146	148	PF00082	0.256
CLV_PCSK_KEX2_1	183	185	PF00082	0.244
CLV_PCSK_KEX2_1	205	207	PF00082	0.265
CLV_PCSK_KEX2_1	224	226	PF00082	0.332
CLV_PCSK_KEX2_1	54	56	PF00082	0.253
CLV_PCSK_PC1ET2_1	129	131	PF00082	0.253
CLV_PCSK_PC1ET2_1	146	148	PF00082	0.253
CLV_PCSK_PC1ET2_1	205	207	PF00082	0.265
CLV_PCSK_PC1ET2_1	54	56	PF00082	0.253
CLV_PCSK_PC7_1	142	148	PF00082	0.253
CLV_PCSK_SKI1_1	121	125	PF00082	0.249
CLV_PCSK_SKI1_1	142	146	PF00082	0.253
CLV_PCSK_SKI1_1	193	197	PF00082	0.253
CLV_PCSK_SKI1_1	219	223	PF00082	0.251
CLV_PCSK_SKI1_1	51	55	PF00082	0.253
CLV_PCSK_SKI1_1	67	71	PF00082	0.253
CLV_PCSK_SKI1_1	92	96	PF00082	0.292
CLV_Separin_Metazoa	82	86	PF03568	0.533
DEG_SCF_FBW7_1	15	22	PF00400	0.434
DOC_CKS1_1	16	21	PF01111	0.437
DOC_CYCLIN_RxL_1	64	74	PF00134	0.467
DOC_MAPK_gen_1	98	107	PF00069	0.446
DOC_SPAK_OSR1_1	85	89	PF12202	0.453
DOC_USP7_MATH_1	122	126	PF00917	0.554
DOC_WW_Pin1_4	15	20	PF00397	0.433
LIG_14-3-3_CanoR_1	159	167	PF00244	0.456
LIG_14-3-3_CanoR_1	186	195	PF00244	0.455
LIG_14-3-3_CanoR_1	224	229	PF00244	0.469
LIG_14-3-3_CanoR_1	98	108	PF00244	0.480
LIG_APCC_ABBA_1	195	200	PF00400	0.465
LIG_BRCT_BRCA1_1	163	167	PF00533	0.379
LIG_BRCT_BRCA1_1	226	230	PF00533	0.503
LIG_Clathr_ClatBox_1	69	73	PF01394	0.467
LIG_eIF4E_1	108	114	PF01652	0.453
LIG_FHA_1	100	106	PF00498	0.480
LIG_FHA_1	122	128	PF00498	0.453
LIG_FHA_1	16	22	PF00498	0.436
LIG_FHA_2	33	39	PF00498	0.409
LIG_FHA_2	66	72	PF00498	0.467
LIG_LIR_Gen_1	164	175	PF02991	0.505
LIG_LIR_Nem_3	164	170	PF02991	0.505
LIG_Pex14_2	228	232	PF04695	0.451
LIG_SH2_CRK	218	222	PF00017	0.439
LIG_SH2_STAT3	152	155	PF00017	0.453
LIG_SH2_STAT5	134	137	PF00017	0.471
LIG_SH2_STAT5	216	219	PF00017	0.532
LIG_SH2_STAT5	34	37	PF00017	0.419
LIG_SH2_STAT5	46	49	PF00017	0.471
LIG_SH3_3	103	109	PF00018	0.419
LIG_SH3_3	91	97	PF00018	0.478
LIG_SUMO_SIM_par_1	18	24	PF11976	0.436
LIG_TRAF2_1	60	63	PF00917	0.429
LIG_UBA3_1	69	77	PF00899	0.453
MOD_CK1_1	160	166	PF00069	0.453
MOD_CK1_1	56	62	PF00069	0.424
MOD_CK1_1	75	81	PF00069	0.476
MOD_CK1_1	99	105	PF00069	0.533
MOD_CK2_1	122	128	PF00069	0.533
MOD_CK2_1	32	38	PF00069	0.418
MOD_CK2_1	56	62	PF00069	0.453
MOD_CK2_1	65	71	PF00069	0.453
MOD_CK2_1	87	93	PF00069	0.554
MOD_Cter_Amidation	181	184	PF01082	0.253
MOD_GlcNHglycan	163	166	PF01048	0.232
MOD_GlcNHglycan	89	92	PF01048	0.315
MOD_GSK3_1	15	22	PF00069	0.434
MOD_GSK3_1	157	164	PF00069	0.512
MOD_GSK3_1	53	60	PF00069	0.554
MOD_GSK3_1	61	68	PF00069	0.377
MOD_GSK3_1	71	78	PF00069	0.447
MOD_NEK2_1	21	26	PF00069	0.401
MOD_NEK2_1	3	8	PF00069	0.444
MOD_NEK2_1	32	37	PF00069	0.530
MOD_NEK2_1	53	58	PF00069	0.440
MOD_NEK2_1	61	66	PF00069	0.552
MOD_NEK2_1	72	77	PF00069	0.337
MOD_PKA_1	142	148	PF00069	0.448
MOD_PKA_1	224	230	PF00069	0.532
MOD_PKA_2	224	230	PF00069	0.532
MOD_PKB_1	184	192	PF00069	0.465
MOD_PKB_1	204	212	PF00069	0.321
MOD_Plk_1	61	67	PF00069	0.484
MOD_Plk_4	65	71	PF00069	0.467
MOD_ProDKin_1	15	21	PF00069	0.434
MOD_SUMO_rev_2	200	207	PF00179	0.451
MOD_SUMO_rev_2	90	97	PF00179	0.379
TRG_ENDOCYTIC_2	134	137	PF00928	0.471
TRG_ENDOCYTIC_2	218	221	PF00928	0.439
TRG_ER_diArg_1	183	185	PF00400	0.451
TRG_ER_diArg_1	204	207	PF00400	0.465
TRG_NLS_MonoExtC_3	47	52	PF00514	0.406
TRG_NLS_MonoExtC_3	53	58	PF00514	0.453
TRG_NLS_MonoExtN_4	45	52	PF00514	0.407
TRG_Pf-PMV_PEXEL_1	121	126	PF00026	0.267
TRG_Pf-PMV_PEXEL_1	67	71	PF00026	0.255

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PA77	Leptomonas seymouri	88%	100%
A0A0S4JIP7	Bodo saltans	70%	100%
A0A1X0P313	Trypanosomatidae	78%	100%
A0A3R7M7D1	Trypanosoma rangeli	78%	100%
A0A3S7WNJ7	Leishmania donovani	92%	100%
A4H368	Leishmania braziliensis	100%	100%
A4HRG4	Leishmania infantum	92%	100%
A6H769	Bos taurus	36%	100%
C9ZXI9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	78%	100%
E9AC32	Leishmania major	91%	100%
E9AJC9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
O43105	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	40%	100%
P02362	Xenopus laevis	37%	100%
P26786	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	38%	100%
P33514	Anopheles gambiae	37%	100%
P48155	Manduca sexta	35%	100%
P48164	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	39%	100%
P50894	Takifugu rubripes	36%	100%
P62081	Homo sapiens	36%	100%
P62082	Mus musculus	36%	100%
P62083	Rattus norvegicus	36%	100%
P62084	Danio rerio	37%	100%
P62085	Drosophila yakuba	37%	100%
Q10101	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	41%	100%
Q23312	Caenorhabditis elegans	33%	100%
Q54I41	Dictyostelium discoideum	41%	100%
Q5AJ93	Candida albicans (strain SC5314 / ATCC MYA-2876)	38%	100%
Q5RT64	Felis catus	36%	100%
Q8LD03	Arabidopsis thaliana	37%	100%
Q8LJU5	Oryza sativa subsp. japonica	35%	100%
Q90YR7	Ictalurus punctatus	37%	100%
Q949H0	Hordeum vulgare	36%	100%
Q962S0	Spodoptera frugiperda	35%	100%
Q9C514	Arabidopsis thaliana	40%	100%
Q9M885	Arabidopsis thaliana	37%	100%
Q9NB21	Culex quinquefasciatus	37%	100%
Q9VA91	Drosophila melanogaster	37%	100%
Q9XET4	Secale cereale	34%	100%
Q9XH45	Brassica oleracea	36%	100%
Q9ZNS1	Avicennia marina	39%	100%