Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4H332_LEIBR

TriTrypDb:

LbrM.01.0010 , LBRM2903_010011800

Length:

964

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H332

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H332

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	134	138	PF00656	0.570
CLV_C14_Caspase3-7	34	38	PF00656	0.581
CLV_C14_Caspase3-7	467	471	PF00656	0.628
CLV_C14_Caspase3-7	564	568	PF00656	0.581
CLV_C14_Caspase3-7	716	720	PF00656	0.640
CLV_NRD_NRD_1	10	12	PF00675	0.588
CLV_NRD_NRD_1	339	341	PF00675	0.601
CLV_NRD_NRD_1	456	458	PF00675	0.632
CLV_NRD_NRD_1	490	492	PF00675	0.566
CLV_NRD_NRD_1	600	602	PF00675	0.662
CLV_NRD_NRD_1	753	755	PF00675	0.513
CLV_NRD_NRD_1	809	811	PF00675	0.578
CLV_PCSK_KEX2_1	10	12	PF00082	0.588
CLV_PCSK_KEX2_1	339	341	PF00082	0.601
CLV_PCSK_KEX2_1	456	458	PF00082	0.632
CLV_PCSK_KEX2_1	490	492	PF00082	0.566
CLV_PCSK_KEX2_1	600	602	PF00082	0.662
CLV_PCSK_KEX2_1	753	755	PF00082	0.507
CLV_PCSK_KEX2_1	809	811	PF00082	0.578
CLV_PCSK_PC7_1	749	755	PF00082	0.411
CLV_PCSK_SKI1_1	301	305	PF00082	0.351
CLV_PCSK_SKI1_1	327	331	PF00082	0.496
CLV_PCSK_SKI1_1	352	356	PF00082	0.567
CLV_PCSK_SKI1_1	54	58	PF00082	0.587
CLV_PCSK_SKI1_1	606	610	PF00082	0.564
DEG_APCC_DBOX_1	300	308	PF00400	0.393
DEG_COP1_1	183	194	PF00400	0.579
DEG_COP1_1	553	563	PF00400	0.566
DEG_SCF_FBW7_2	418	423	PF00400	0.554
DOC_ANK_TNKS_1	839	846	PF00023	0.535
DOC_CDC14_PxL_1	729	737	PF14671	0.492
DOC_CKS1_1	344	349	PF01111	0.551
DOC_CKS1_1	552	557	PF01111	0.593
DOC_CKS1_1	861	866	PF01111	0.550
DOC_CYCLIN_RxL_1	600	613	PF00134	0.561
DOC_PP2B_LxvP_1	161	164	PF13499	0.604
DOC_PP4_FxxP_1	162	165	PF00568	0.562
DOC_PP4_FxxP_1	638	641	PF00568	0.577
DOC_USP7_MATH_1	125	129	PF00917	0.553
DOC_USP7_MATH_1	130	134	PF00917	0.554
DOC_USP7_MATH_1	16	20	PF00917	0.604
DOC_USP7_MATH_1	248	252	PF00917	0.629
DOC_USP7_MATH_1	30	34	PF00917	0.585
DOC_USP7_MATH_1	364	368	PF00917	0.542
DOC_USP7_MATH_1	561	565	PF00917	0.622
DOC_USP7_MATH_1	572	576	PF00917	0.597
DOC_USP7_MATH_1	619	623	PF00917	0.600
DOC_USP7_MATH_1	634	638	PF00917	0.519
DOC_USP7_MATH_1	67	71	PF00917	0.576
DOC_USP7_MATH_1	677	681	PF00917	0.641
DOC_USP7_MATH_1	796	800	PF00917	0.567
DOC_USP7_MATH_1	911	915	PF00917	0.517
DOC_WW_Pin1_4	146	151	PF00397	0.585
DOC_WW_Pin1_4	18	23	PF00397	0.605
DOC_WW_Pin1_4	343	348	PF00397	0.571
DOC_WW_Pin1_4	374	379	PF00397	0.535
DOC_WW_Pin1_4	38	43	PF00397	0.543
DOC_WW_Pin1_4	396	401	PF00397	0.683
DOC_WW_Pin1_4	416	421	PF00397	0.528
DOC_WW_Pin1_4	490	495	PF00397	0.575
DOC_WW_Pin1_4	551	556	PF00397	0.598
DOC_WW_Pin1_4	610	615	PF00397	0.663
DOC_WW_Pin1_4	632	637	PF00397	0.556
DOC_WW_Pin1_4	642	647	PF00397	0.537
DOC_WW_Pin1_4	719	724	PF00397	0.623
DOC_WW_Pin1_4	790	795	PF00397	0.677
DOC_WW_Pin1_4	860	865	PF00397	0.549
DOC_WW_Pin1_4	947	952	PF00397	0.663
DOC_WW_Pin1_4	97	102	PF00397	0.569
LIG_14-3-3_CanoR_1	15	21	PF00244	0.623
LIG_14-3-3_CanoR_1	156	162	PF00244	0.603
LIG_14-3-3_CanoR_1	270	278	PF00244	0.454
LIG_14-3-3_CanoR_1	290	295	PF00244	0.317
LIG_14-3-3_CanoR_1	368	375	PF00244	0.551
LIG_14-3-3_CanoR_1	394	398	PF00244	0.561
LIG_14-3-3_CanoR_1	514	522	PF00244	0.602
LIG_14-3-3_CanoR_1	580	586	PF00244	0.566
LIG_14-3-3_CanoR_1	600	605	PF00244	0.554
LIG_14-3-3_CanoR_1	606	615	PF00244	0.546
LIG_14-3-3_CanoR_1	664	670	PF00244	0.575
LIG_14-3-3_CanoR_1	683	688	PF00244	0.581
LIG_14-3-3_CanoR_1	701	710	PF00244	0.511
LIG_14-3-3_CanoR_1	759	768	PF00244	0.484
LIG_14-3-3_CanoR_1	776	784	PF00244	0.497
LIG_14-3-3_CanoR_1	787	795	PF00244	0.621
LIG_14-3-3_CanoR_1	97	101	PF00244	0.567
LIG_BIR_II_1	1	5	PF00653	0.590
LIG_BIR_III_4	567	571	PF00653	0.556
LIG_BRCT_BRCA1_1	530	534	PF00533	0.647
LIG_CSL_BTD_1	403	406	PF09270	0.624
LIG_EVH1_1	44	48	PF00568	0.568
LIG_FHA_1	156	162	PF00498	0.607
LIG_FHA_1	210	216	PF00498	0.523
LIG_FHA_1	223	229	PF00498	0.462
LIG_FHA_1	294	300	PF00498	0.462
LIG_FHA_1	443	449	PF00498	0.547
LIG_FHA_1	480	486	PF00498	0.598
LIG_FHA_1	555	561	PF00498	0.587
LIG_FHA_1	580	586	PF00498	0.566
LIG_FHA_1	720	726	PF00498	0.571
LIG_FHA_1	763	769	PF00498	0.401
LIG_FHA_1	816	822	PF00498	0.541
LIG_FHA_1	824	830	PF00498	0.510
LIG_FHA_1	87	93	PF00498	0.570
LIG_FHA_2	149	155	PF00498	0.579
LIG_FHA_2	164	170	PF00498	0.555
LIG_FHA_2	182	188	PF00498	0.549
LIG_FHA_2	417	423	PF00498	0.556
LIG_FHA_2	714	720	PF00498	0.639
LIG_LIR_Apic_2	107	112	PF02991	0.566
LIG_LIR_Apic_2	159	165	PF02991	0.568
LIG_LIR_Apic_2	374	378	PF02991	0.533
LIG_LIR_Apic_2	635	641	PF02991	0.571
LIG_LIR_Gen_1	122	132	PF02991	0.541
LIG_LIR_Gen_1	531	540	PF02991	0.592
LIG_LIR_Nem_3	122	127	PF02991	0.542
LIG_LIR_Nem_3	531	537	PF02991	0.593
LIG_LIR_Nem_3	704	710	PF02991	0.652
LIG_MYND_1	42	46	PF01753	0.597
LIG_PCNA_PIPBox_1	761	770	PF02747	0.401
LIG_PCNA_yPIPBox_3	276	286	PF02747	0.514
LIG_SH2_CRK	109	113	PF00017	0.560
LIG_SH2_NCK_1	109	113	PF00017	0.560
LIG_SH2_SRC	109	112	PF00017	0.563
LIG_SH2_SRC	474	477	PF00017	0.565
LIG_SH2_STAP1	205	209	PF00017	0.520
LIG_SH2_STAP1	827	831	PF00017	0.524
LIG_SH2_STAT3	690	693	PF00017	0.576
LIG_SH2_STAT5	203	206	PF00017	0.537
LIG_SH2_STAT5	266	269	PF00017	0.530
LIG_SH2_STAT5	474	477	PF00017	0.565
LIG_SH2_STAT5	690	693	PF00017	0.576
LIG_SH3_1	10	16	PF00018	0.587
LIG_SH3_1	147	153	PF00018	0.579
LIG_SH3_3	10	16	PF00018	0.587
LIG_SH3_3	124	130	PF00018	0.541
LIG_SH3_3	147	153	PF00018	0.579
LIG_SH3_3	186	192	PF00018	0.578
LIG_SH3_3	196	202	PF00018	0.512
LIG_SH3_3	259	265	PF00018	0.528
LIG_SH3_3	39	45	PF00018	0.613
LIG_SH3_3	493	499	PF00018	0.603
LIG_SH3_3	549	555	PF00018	0.628
LIG_SH3_3	575	581	PF00018	0.565
LIG_SH3_3	74	80	PF00018	0.576
LIG_SH3_3	858	864	PF00018	0.544
LIG_SH3_3	919	925	PF00018	0.552
LIG_SH3_3	943	949	PF00018	0.602
LIG_SUMO_SIM_par_1	166	172	PF11976	0.569
LIG_SUMO_SIM_par_1	556	562	PF11976	0.565
LIG_SUMO_SIM_par_1	924	931	PF11976	0.562
LIG_TRAF2_1	748	751	PF00917	0.519
LIG_TRAF2_1	931	934	PF00917	0.545
LIG_UBA3_1	167	173	PF00899	0.571
LIG_WRC_WIRS_1	291	296	PF05994	0.363
LIG_WW_2	45	48	PF00397	0.561
LIG_WW_3	7	11	PF00397	0.583
MOD_CDK_SPK_2	860	865	PF00069	0.549
MOD_CDK_SPxxK_3	610	617	PF00069	0.568
MOD_CK1_1	133	139	PF00069	0.598
MOD_CK1_1	141	147	PF00069	0.601
MOD_CK1_1	155	161	PF00069	0.554
MOD_CK1_1	18	24	PF00069	0.581
MOD_CK1_1	208	214	PF00069	0.527
MOD_CK1_1	235	241	PF00069	0.596
MOD_CK1_1	253	259	PF00069	0.488
MOD_CK1_1	269	275	PF00069	0.448
MOD_CK1_1	293	299	PF00069	0.380
MOD_CK1_1	331	337	PF00069	0.533
MOD_CK1_1	367	373	PF00069	0.577
MOD_CK1_1	38	44	PF00069	0.545
MOD_CK1_1	462	468	PF00069	0.643
MOD_CK1_1	513	519	PF00069	0.600
MOD_CK1_1	523	529	PF00069	0.564
MOD_CK1_1	550	556	PF00069	0.567
MOD_CK1_1	610	616	PF00069	0.664
MOD_CK1_1	63	69	PF00069	0.569
MOD_CK1_1	697	703	PF00069	0.594
MOD_CK1_1	715	721	PF00069	0.534
MOD_CK1_1	762	768	PF00069	0.398
MOD_CK1_1	785	791	PF00069	0.649
MOD_CK1_1	799	805	PF00069	0.559
MOD_CK1_1	846	852	PF00069	0.630
MOD_CK1_1	880	886	PF00069	0.577
MOD_CK1_1	905	911	PF00069	0.534
MOD_CK1_1	96	102	PF00069	0.556
MOD_CK2_1	148	154	PF00069	0.579
MOD_CK2_1	181	187	PF00069	0.582
MOD_CK2_1	556	562	PF00069	0.643
MOD_CK2_1	644	650	PF00069	0.681
MOD_CK2_1	675	681	PF00069	0.664
MOD_CK2_1	928	934	PF00069	0.545
MOD_Cter_Amidation	488	491	PF01082	0.561
MOD_DYRK1A_RPxSP_1	860	864	PF00069	0.544
MOD_DYRK1A_RPxSP_1	947	951	PF00069	0.559
MOD_DYRK1A_RPxSP_1	97	101	PF00069	0.569
MOD_GlcNHglycan	1	4	PF01048	0.589
MOD_GlcNHglycan	121	124	PF01048	0.559
MOD_GlcNHglycan	127	130	PF01048	0.550
MOD_GlcNHglycan	176	179	PF01048	0.622
MOD_GlcNHglycan	22	25	PF01048	0.582
MOD_GlcNHglycan	240	243	PF01048	0.526
MOD_GlcNHglycan	256	259	PF01048	0.554
MOD_GlcNHglycan	334	337	PF01048	0.550
MOD_GlcNHglycan	37	41	PF01048	0.575
MOD_GlcNHglycan	370	373	PF01048	0.549
MOD_GlcNHglycan	461	464	PF01048	0.580
MOD_GlcNHglycan	522	525	PF01048	0.651
MOD_GlcNHglycan	574	577	PF01048	0.595
MOD_GlcNHglycan	628	631	PF01048	0.643
MOD_GlcNHglycan	632	635	PF01048	0.601
MOD_GlcNHglycan	704	707	PF01048	0.650
MOD_GlcNHglycan	74	77	PF01048	0.577
MOD_GlcNHglycan	761	764	PF01048	0.497
MOD_GlcNHglycan	788	791	PF01048	0.590
MOD_GlcNHglycan	800	805	PF01048	0.533
MOD_GlcNHglycan	869	872	PF01048	0.663
MOD_GlcNHglycan	930	933	PF01048	0.542
MOD_GlcNHglycan	960	963	PF01048	0.530
MOD_GSK3_1	119	126	PF00069	0.540
MOD_GSK3_1	136	143	PF00069	0.551
MOD_GSK3_1	14	21	PF00069	0.600
MOD_GSK3_1	148	155	PF00069	0.588
MOD_GSK3_1	168	175	PF00069	0.520
MOD_GSK3_1	183	190	PF00069	0.564
MOD_GSK3_1	205	212	PF00069	0.549
MOD_GSK3_1	231	238	PF00069	0.533
MOD_GSK3_1	242	249	PF00069	0.580
MOD_GSK3_1	250	257	PF00069	0.566
MOD_GSK3_1	266	273	PF00069	0.456
MOD_GSK3_1	328	335	PF00069	0.556
MOD_GSK3_1	360	367	PF00069	0.551
MOD_GSK3_1	385	392	PF00069	0.575
MOD_GSK3_1	459	466	PF00069	0.675
MOD_GSK3_1	475	482	PF00069	0.515
MOD_GSK3_1	510	517	PF00069	0.659
MOD_GSK3_1	526	533	PF00069	0.515
MOD_GSK3_1	54	61	PF00069	0.584
MOD_GSK3_1	546	553	PF00069	0.674
MOD_GSK3_1	615	622	PF00069	0.563
MOD_GSK3_1	626	633	PF00069	0.592
MOD_GSK3_1	63	70	PF00069	0.546
MOD_GSK3_1	640	647	PF00069	0.609
MOD_GSK3_1	677	684	PF00069	0.635
MOD_GSK3_1	697	704	PF00069	0.505
MOD_GSK3_1	713	720	PF00069	0.504
MOD_GSK3_1	724	731	PF00069	0.551
MOD_GSK3_1	782	789	PF00069	0.634
MOD_GSK3_1	796	803	PF00069	0.558
MOD_GSK3_1	843	850	PF00069	0.590
MOD_GSK3_1	924	931	PF00069	0.628
MOD_GSK3_1	93	100	PF00069	0.576
MOD_N-GLC_1	209	214	PF02516	0.515
MOD_N-GLC_1	526	531	PF02516	0.637
MOD_N-GLC_1	615	620	PF02516	0.664
MOD_N-GLC_1	737	742	PF02516	0.455
MOD_N-GLC_1	86	91	PF02516	0.567
MOD_N-GLC_1	940	945	PF02516	0.573
MOD_NEK2_1	231	236	PF00069	0.499
MOD_NEK2_1	330	335	PF00069	0.514
MOD_NEK2_1	385	390	PF00069	0.558
MOD_NEK2_1	530	535	PF00069	0.602
MOD_NEK2_1	546	551	PF00069	0.618
MOD_NEK2_1	608	613	PF00069	0.567
MOD_NEK2_1	62	67	PF00069	0.568
MOD_NEK2_1	649	654	PF00069	0.611
MOD_NEK2_1	662	667	PF00069	0.545
MOD_NEK2_1	717	722	PF00069	0.540
MOD_NEK2_1	724	729	PF00069	0.528
MOD_NEK2_1	786	791	PF00069	0.630
MOD_NEK2_1	823	828	PF00069	0.534
MOD_NEK2_1	85	90	PF00069	0.565
MOD_NEK2_1	867	872	PF00069	0.672
MOD_NEK2_1	912	917	PF00069	0.592
MOD_NEK2_2	224	229	PF00069	0.519
MOD_PIKK_1	104	110	PF00454	0.572
MOD_PIKK_1	141	147	PF00454	0.587
MOD_PIKK_1	23	29	PF00454	0.580
MOD_PIKK_1	271	277	PF00454	0.447
MOD_PIKK_1	913	919	PF00454	0.595
MOD_PK_1	514	520	PF00069	0.664
MOD_PK_1	600	606	PF00069	0.556
MOD_PKA_1	600	606	PF00069	0.556
MOD_PKA_2	14	20	PF00069	0.626
MOD_PKA_2	155	161	PF00069	0.588
MOD_PKA_2	269	275	PF00069	0.471
MOD_PKA_2	331	337	PF00069	0.547
MOD_PKA_2	367	373	PF00069	0.553
MOD_PKA_2	393	399	PF00069	0.590
MOD_PKA_2	513	519	PF00069	0.600
MOD_PKA_2	579	585	PF00069	0.567
MOD_PKA_2	600	606	PF00069	0.556
MOD_PKA_2	665	671	PF00069	0.593
MOD_PKA_2	694	700	PF00069	0.643
MOD_PKA_2	775	781	PF00069	0.540
MOD_PKA_2	78	84	PF00069	0.574
MOD_PKA_2	786	792	PF00069	0.628
MOD_PKA_2	96	102	PF00069	0.522
MOD_PKB_1	288	296	PF00069	0.369
MOD_Plk_1	205	211	PF00069	0.551
MOD_Plk_1	364	370	PF00069	0.548
MOD_Plk_1	463	469	PF00069	0.654
MOD_Plk_1	475	481	PF00069	0.551
MOD_Plk_1	526	532	PF00069	0.586
MOD_Plk_1	561	567	PF00069	0.559
MOD_Plk_1	649	655	PF00069	0.585
MOD_Plk_1	713	719	PF00069	0.536
MOD_Plk_1	905	911	PF00069	0.504
MOD_Plk_2-3	464	470	PF00069	0.555
MOD_Plk_2-3	562	568	PF00069	0.560
MOD_Plk_4	157	163	PF00069	0.575
MOD_Plk_4	600	606	PF00069	0.556
MOD_Plk_4	924	930	PF00069	0.585
MOD_ProDKin_1	146	152	PF00069	0.584
MOD_ProDKin_1	18	24	PF00069	0.604
MOD_ProDKin_1	343	349	PF00069	0.571
MOD_ProDKin_1	374	380	PF00069	0.536
MOD_ProDKin_1	38	44	PF00069	0.545
MOD_ProDKin_1	396	402	PF00069	0.680
MOD_ProDKin_1	416	422	PF00069	0.527
MOD_ProDKin_1	490	496	PF00069	0.573
MOD_ProDKin_1	551	557	PF00069	0.599
MOD_ProDKin_1	610	616	PF00069	0.664
MOD_ProDKin_1	632	638	PF00069	0.559
MOD_ProDKin_1	642	648	PF00069	0.538
MOD_ProDKin_1	719	725	PF00069	0.625
MOD_ProDKin_1	790	796	PF00069	0.673
MOD_ProDKin_1	860	866	PF00069	0.552
MOD_ProDKin_1	947	953	PF00069	0.560
MOD_ProDKin_1	97	103	PF00069	0.570
TRG_DiLeu_BaEn_4	750	756	PF01217	0.511
TRG_DiLeu_BaEn_4	874	880	PF01217	0.561
TRG_DiLeu_BaLyEn_6	504	509	PF01217	0.568
TRG_ER_diArg_1	308	311	PF00400	0.456
TRG_ER_diArg_1	415	418	PF00400	0.561
TRG_ER_diArg_1	490	492	PF00400	0.571
TRG_ER_diArg_1	502	505	PF00400	0.566
TRG_ER_diArg_1	599	601	PF00400	0.652
TRG_ER_diArg_1	753	756	PF00400	0.510
TRG_ER_diArg_1	809	811	PF00400	0.578
TRG_ER_diArg_1	851	854	PF00400	0.580
TRG_ER_diArg_1	9	11	PF00400	0.589
TRG_Pf-PMV_PEXEL_1	753	758	PF00026	0.488

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H4W2	Leishmania donovani	46%	100%
A4HRI6	Leishmania infantum	47%	100%
E9AJF0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	45%	93%