Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A451EJR9_LEIDO

TriTrypDb:

LdBPK_030680.1 , LdCL_030012000 , LDHU3_03.0770

Length:

2887

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A451EJR9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

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Biological processes
Term	Name	Level	Count
GO:0007015	actin filament organization	5	2
GO:0009987	cellular process	1	2
GO:0016043	cellular component organization	3	2
GO:0045010	actin nucleation	6	2
GO:0071840	cellular component organization or biogenesis	2	2
GO:0097435	supramolecular fiber organization	4	2

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Molecular functions
Term	Name	Level	Count
GO:0003779	actin binding	4	2
GO:0005488	binding	1	2
GO:0005515	protein binding	2	2
GO:0008092	cytoskeletal protein binding	3	2
GO:0044877	protein-containing complex binding	2	2
GO:0051015	actin filament binding	3	2

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1362	1366	PF00656	0.538
CLV_C14_Caspase3-7	1404	1408	PF00656	0.388
CLV_C14_Caspase3-7	1485	1489	PF00656	0.500
CLV_C14_Caspase3-7	1723	1727	PF00656	0.677
CLV_C14_Caspase3-7	1830	1834	PF00656	0.481
CLV_C14_Caspase3-7	190	194	PF00656	0.636
CLV_C14_Caspase3-7	2022	2026	PF00656	0.342
CLV_C14_Caspase3-7	254	258	PF00656	0.556
CLV_C14_Caspase3-7	2609	2613	PF00656	0.636
CLV_C14_Caspase3-7	2674	2678	PF00656	0.434

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IHS7	Leptomonas seymouri	44%	100%
A4H3N1	Leishmania braziliensis	69%	99%
A4HRV8	Leishmania infantum	99%	100%
E9ACL5	Leishmania major	88%	97%
E9AJV3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	99%

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