EamA-like transporter family/Triose-phosphate Transporter family/UAA transporter family, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

UAA transporter family, putative

Species:

Leishmania donovani

UniProt:

A0A451EJH0_LEIDO

TriTrypDb:

LdBPK_020310.1 , LdCL_020008500 , LDHU3_02.0420

Length:

972

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	5
GO:0110165	cellular anatomical entity	1	5

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Expansion

Sequence features

A0A451EJH0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A451EJH0

Function

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Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	5
GO:0009987	cellular process	1	5
GO:0051179	localization	1	5
GO:0051234	establishment of localization	2	5
GO:0055085	transmembrane transport	2	5

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Molecular functions
Term	Name	Level	Count
GO:0005215	transporter activity	1	1
GO:0022857	transmembrane transporter activity	2	1

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	307	311	PF00656	0.806
CLV_C14_Caspase3-7	323	327	PF00656	0.663
CLV_C14_Caspase3-7	331	335	PF00656	0.672
CLV_C14_Caspase3-7	543	547	PF00656	0.445
CLV_NRD_NRD_1	105	107	PF00675	0.534
CLV_NRD_NRD_1	230	232	PF00675	0.477
CLV_NRD_NRD_1	324	326	PF00675	0.513
CLV_NRD_NRD_1	357	359	PF00675	0.599
CLV_NRD_NRD_1	397	399	PF00675	0.616
CLV_NRD_NRD_1	509	511	PF00675	0.447

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A4H3D0	Leishmania braziliensis	59%	98%
A4HRN1	Leishmania infantum	99%	100%
E9ACA9	Leishmania major	85%	100%
E9AJJ7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	78%	96%

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