BRCT domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A451EJD8_LEIDO

TriTrypDb:

LdCL_010013800

Length:

739

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A451EJD8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A451EJD8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	148	152	PF00656	0.351
CLV_C14_Caspase3-7	242	246	PF00656	0.373
CLV_C14_Caspase3-7	269	273	PF00656	0.384
CLV_C14_Caspase3-7	296	300	PF00656	0.657
CLV_C14_Caspase3-7	53	57	PF00656	0.354
CLV_C14_Caspase3-7	80	84	PF00656	0.383
CLV_C14_Caspase3-7	94	98	PF00656	0.325
CLV_NRD_NRD_1	317	319	PF00675	0.553
CLV_NRD_NRD_1	428	430	PF00675	0.582
CLV_NRD_NRD_1	509	511	PF00675	0.582
CLV_NRD_NRD_1	590	592	PF00675	0.578
CLV_NRD_NRD_1	644	646	PF00675	0.579
CLV_PCSK_KEX2_1	317	319	PF00082	0.553
CLV_PCSK_KEX2_1	427	429	PF00082	0.576
CLV_PCSK_KEX2_1	508	510	PF00082	0.586
CLV_PCSK_KEX2_1	589	591	PF00082	0.584
CLV_PCSK_KEX2_1	643	645	PF00082	0.584
CLV_PCSK_KEX2_1	729	731	PF00082	0.533
CLV_PCSK_PC1ET2_1	729	731	PF00082	0.533
DEG_Nend_UBRbox_1	1	4	PF02207	0.501
DOC_CKS1_1	334	339	PF01111	0.557
DOC_CKS1_1	361	366	PF01111	0.554
DOC_CKS1_1	442	447	PF01111	0.564
DOC_CKS1_1	469	474	PF01111	0.600
DOC_CKS1_1	496	501	PF01111	0.597
DOC_CKS1_1	523	528	PF01111	0.594
DOC_CKS1_1	550	555	PF01111	0.595
DOC_CKS1_1	577	582	PF01111	0.566
DOC_CKS1_1	604	609	PF01111	0.566
DOC_CKS1_1	631	636	PF01111	0.562
DOC_CKS1_1	658	663	PF01111	0.565
DOC_CKS1_1	685	690	PF01111	0.542
DOC_CYCLIN_yCln2_LP_2	334	340	PF00134	0.552
DOC_CYCLIN_yCln2_LP_2	361	367	PF00134	0.549
DOC_CYCLIN_yCln2_LP_2	415	421	PF00134	0.564
DOC_CYCLIN_yCln2_LP_2	469	475	PF00134	0.597
DOC_CYCLIN_yCln2_LP_2	496	502	PF00134	0.594
DOC_CYCLIN_yCln2_LP_2	550	556	PF00134	0.590
DOC_CYCLIN_yCln2_LP_2	577	583	PF00134	0.565
DOC_CYCLIN_yCln2_LP_2	604	610	PF00134	0.563
DOC_CYCLIN_yCln2_LP_2	631	637	PF00134	0.559
DOC_CYCLIN_yCln2_LP_2	658	664	PF00134	0.564
DOC_CYCLIN_yCln2_LP_2	685	691	PF00134	0.536
DOC_MAPK_gen_1	729	736	PF00069	0.524
DOC_MAPK_RevD_3	413	429	PF00069	0.564
DOC_MAPK_RevD_3	494	510	PF00069	0.572
DOC_MAPK_RevD_3	575	591	PF00069	0.568
DOC_MAPK_RevD_3	629	645	PF00069	0.567
DOC_PP2B_LxvP_1	415	418	PF13499	0.573
DOC_USP7_MATH_1	447	451	PF00917	0.799
DOC_USP7_MATH_1	528	532	PF00917	0.601
DOC_WW_Pin1_4	333	338	PF00397	0.562
DOC_WW_Pin1_4	360	365	PF00397	0.688
DOC_WW_Pin1_4	441	446	PF00397	0.749
DOC_WW_Pin1_4	468	473	PF00397	0.783
DOC_WW_Pin1_4	495	500	PF00397	0.595
DOC_WW_Pin1_4	522	527	PF00397	0.803
DOC_WW_Pin1_4	549	554	PF00397	0.630
DOC_WW_Pin1_4	576	581	PF00397	0.567
DOC_WW_Pin1_4	603	608	PF00397	0.570
DOC_WW_Pin1_4	630	635	PF00397	0.792
DOC_WW_Pin1_4	657	662	PF00397	0.565
DOC_WW_Pin1_4	684	689	PF00397	0.545
LIG_14-3-3_CanoR_1	317	323	PF00244	0.695
LIG_14-3-3_CanoR_1	325	334	PF00244	0.607
LIG_14-3-3_CanoR_1	352	361	PF00244	0.784
LIG_14-3-3_CanoR_1	379	388	PF00244	0.670
LIG_14-3-3_CanoR_1	406	415	PF00244	0.614
LIG_14-3-3_CanoR_1	433	442	PF00244	0.566
LIG_14-3-3_CanoR_1	460	469	PF00244	0.597
LIG_14-3-3_CanoR_1	487	496	PF00244	0.601
LIG_14-3-3_CanoR_1	514	523	PF00244	0.731
LIG_14-3-3_CanoR_1	541	550	PF00244	0.586
LIG_14-3-3_CanoR_1	568	577	PF00244	0.767
LIG_14-3-3_CanoR_1	595	604	PF00244	0.596
LIG_14-3-3_CanoR_1	622	631	PF00244	0.574
LIG_14-3-3_CanoR_1	649	658	PF00244	0.770
LIG_14-3-3_CanoR_1	676	685	PF00244	0.569
LIG_FHA_2	240	246	PF00498	0.375
LIG_FHA_2	267	273	PF00498	0.392
LIG_FHA_2	294	300	PF00498	0.484
LIG_FHA_2	51	57	PF00498	0.359
LIG_FHA_2	700	706	PF00498	0.537
LIG_FHA_2	78	84	PF00498	0.389
LIG_SH2_STAP1	709	713	PF00017	0.545
LIG_SH3_3	334	340	PF00018	0.552
LIG_SH3_3	361	367	PF00018	0.549
LIG_SH3_3	415	421	PF00018	0.564
LIG_SH3_3	469	475	PF00018	0.765
LIG_SH3_3	496	502	PF00018	0.594
LIG_SH3_3	530	536	PF00018	0.678
LIG_SH3_3	550	556	PF00018	0.590
LIG_SH3_3	577	583	PF00018	0.565
LIG_SH3_3	604	610	PF00018	0.563
LIG_SH3_3	631	637	PF00018	0.559
LIG_SH3_3	658	664	PF00018	0.564
LIG_SH3_3	685	691	PF00018	0.536
LIG_SH3_3	731	737	PF00018	0.514
LIG_TRAF2_1	702	705	PF00917	0.533
LIG_WW_3	338	342	PF00397	0.551
LIG_WW_3	365	369	PF00397	0.549
LIG_WW_3	392	396	PF00397	0.554
LIG_WW_3	419	423	PF00397	0.558
LIG_WW_3	473	477	PF00397	0.596
LIG_WW_3	500	504	PF00397	0.594
LIG_WW_3	554	558	PF00397	0.595
LIG_WW_3	581	585	PF00397	0.561
LIG_WW_3	608	612	PF00397	0.560
LIG_WW_3	635	639	PF00397	0.554
LIG_WW_3	662	666	PF00397	0.561
LIG_WW_3	689	693	PF00397	0.529
MOD_CK1_1	321	327	PF00069	0.555
MOD_CK2_1	325	331	PF00069	0.564
MOD_CK2_1	352	358	PF00069	0.571
MOD_CK2_1	379	385	PF00069	0.579
MOD_CK2_1	406	412	PF00069	0.579
MOD_CK2_1	433	439	PF00069	0.574
MOD_CK2_1	460	466	PF00069	0.637
MOD_CK2_1	487	493	PF00069	0.605
MOD_CK2_1	514	520	PF00069	0.606
MOD_CK2_1	541	547	PF00069	0.588
MOD_CK2_1	568	574	PF00069	0.585
MOD_CK2_1	595	601	PF00069	0.580
MOD_CK2_1	622	628	PF00069	0.579
MOD_CK2_1	649	655	PF00069	0.571
MOD_CK2_1	676	682	PF00069	0.574
MOD_CK2_1	699	705	PF00069	0.540
MOD_Cter_Amidation	727	730	PF01082	0.537
MOD_GlcNHglycan	112	115	PF01048	0.371
MOD_GlcNHglycan	139	142	PF01048	0.376
MOD_GlcNHglycan	166	169	PF01048	0.380
MOD_GlcNHglycan	193	196	PF01048	0.382
MOD_GlcNHglycan	220	223	PF01048	0.385
MOD_GlcNHglycan	247	250	PF01048	0.412
MOD_GlcNHglycan	274	277	PF01048	0.557
MOD_GlcNHglycan	301	304	PF01048	0.563
MOD_GlcNHglycan	31	34	PF01048	0.388
MOD_GlcNHglycan	341	344	PF01048	0.597
MOD_GlcNHglycan	368	371	PF01048	0.597
MOD_GlcNHglycan	395	398	PF01048	0.601
MOD_GlcNHglycan	422	425	PF01048	0.746
MOD_GlcNHglycan	449	452	PF01048	0.803
MOD_GlcNHglycan	476	479	PF01048	0.612
MOD_GlcNHglycan	503	506	PF01048	0.689
MOD_GlcNHglycan	530	533	PF01048	0.606
MOD_GlcNHglycan	557	560	PF01048	0.699
MOD_GlcNHglycan	58	61	PF01048	0.372
MOD_GlcNHglycan	584	587	PF01048	0.617
MOD_GlcNHglycan	611	614	PF01048	0.633
MOD_GlcNHglycan	638	641	PF01048	0.603
MOD_GlcNHglycan	665	668	PF01048	0.574
MOD_GlcNHglycan	692	695	PF01048	0.552
MOD_GlcNHglycan	85	88	PF01048	0.374
MOD_GSK3_1	106	113	PF00069	0.352
MOD_GSK3_1	118	125	PF00069	0.350
MOD_GSK3_1	133	140	PF00069	0.343
MOD_GSK3_1	160	167	PF00069	0.369
MOD_GSK3_1	172	179	PF00069	0.350
MOD_GSK3_1	187	194	PF00069	0.348
MOD_GSK3_1	199	206	PF00069	0.349
MOD_GSK3_1	214	221	PF00069	0.370
MOD_GSK3_1	226	233	PF00069	0.353
MOD_GSK3_1	241	248	PF00069	0.356
MOD_GSK3_1	25	32	PF00069	0.388
MOD_GSK3_1	253	260	PF00069	0.502
MOD_GSK3_1	268	275	PF00069	0.515
MOD_GSK3_1	280	287	PF00069	0.388
MOD_GSK3_1	321	328	PF00069	0.670
MOD_GSK3_1	348	355	PF00069	0.580
MOD_GSK3_1	37	44	PF00069	0.348
MOD_GSK3_1	375	382	PF00069	0.611
MOD_GSK3_1	402	409	PF00069	0.729
MOD_GSK3_1	429	436	PF00069	0.599
MOD_GSK3_1	456	463	PF00069	0.674
MOD_GSK3_1	483	490	PF00069	0.606
MOD_GSK3_1	510	517	PF00069	0.607
MOD_GSK3_1	52	59	PF00069	0.336
MOD_GSK3_1	537	544	PF00069	0.692
MOD_GSK3_1	564	571	PF00069	0.610
MOD_GSK3_1	591	598	PF00069	0.579
MOD_GSK3_1	618	625	PF00069	0.670
MOD_GSK3_1	64	71	PF00069	0.351
MOD_GSK3_1	645	652	PF00069	0.631
MOD_GSK3_1	672	679	PF00069	0.677
MOD_GSK3_1	79	86	PF00069	0.339
MOD_N-GLC_1	447	452	PF02516	0.576
MOD_N-GLC_1	528	533	PF02516	0.602
MOD_N-GLC_1	715	720	PF02516	0.533
MOD_NEK2_1	715	720	PF00069	0.533
MOD_PIKK_1	387	393	PF00454	0.565
MOD_PKA_2	10	16	PF00069	0.406
MOD_PKA_2	118	124	PF00069	0.374
MOD_PKA_2	145	151	PF00069	0.377
MOD_PKA_2	172	178	PF00069	0.374
MOD_PKA_2	199	205	PF00069	0.374
MOD_PKA_2	226	232	PF00069	0.378
MOD_PKA_2	253	259	PF00069	0.487
MOD_PKA_2	280	286	PF00069	0.403
MOD_PKA_2	307	313	PF00069	0.639
MOD_PKA_2	37	43	PF00069	0.372
MOD_PKA_2	64	70	PF00069	0.376
MOD_PKA_2	91	97	PF00069	0.363
MOD_PKB_1	323	331	PF00069	0.562
MOD_PKB_1	350	358	PF00069	0.571
MOD_PKB_1	377	385	PF00069	0.579
MOD_PKB_1	404	412	PF00069	0.578
MOD_PKB_1	427	435	PF00069	0.580
MOD_PKB_1	458	466	PF00069	0.604
MOD_PKB_1	485	493	PF00069	0.606
MOD_PKB_1	508	516	PF00069	0.602
MOD_PKB_1	539	547	PF00069	0.594
MOD_PKB_1	566	574	PF00069	0.586
MOD_PKB_1	589	597	PF00069	0.580
MOD_PKB_1	620	628	PF00069	0.579
MOD_PKB_1	643	651	PF00069	0.579
MOD_PKB_1	674	682	PF00069	0.575
MOD_Plk_1	528	534	PF00069	0.576
MOD_Plk_4	10	16	PF00069	0.381
MOD_ProDKin_1	333	339	PF00069	0.557
MOD_ProDKin_1	360	366	PF00069	0.682
MOD_ProDKin_1	441	447	PF00069	0.750
MOD_ProDKin_1	468	474	PF00069	0.783
MOD_ProDKin_1	495	501	PF00069	0.595
MOD_ProDKin_1	522	528	PF00069	0.802
MOD_ProDKin_1	549	555	PF00069	0.631
MOD_ProDKin_1	576	582	PF00069	0.563
MOD_ProDKin_1	603	609	PF00069	0.565
MOD_ProDKin_1	630	636	PF00069	0.786
MOD_ProDKin_1	657	663	PF00069	0.564
MOD_ProDKin_1	684	690	PF00069	0.539
TRG_ER_diArg_1	322	325	PF00400	0.559
TRG_ER_diArg_1	349	352	PF00400	0.574
TRG_ER_diArg_1	376	379	PF00400	0.581
TRG_ER_diArg_1	403	406	PF00400	0.575
TRG_ER_diArg_1	427	429	PF00400	0.576
TRG_ER_diArg_1	430	433	PF00400	0.581
TRG_ER_diArg_1	457	460	PF00400	0.832
TRG_ER_diArg_1	484	487	PF00400	0.608
TRG_ER_diArg_1	508	510	PF00400	0.607
TRG_ER_diArg_1	511	514	PF00400	0.605
TRG_ER_diArg_1	538	541	PF00400	0.612
TRG_ER_diArg_1	565	568	PF00400	0.841
TRG_ER_diArg_1	589	591	PF00400	0.584
TRG_ER_diArg_1	592	595	PF00400	0.573
TRG_ER_diArg_1	619	622	PF00400	0.579
TRG_ER_diArg_1	643	645	PF00400	0.584
TRG_ER_diArg_1	646	649	PF00400	0.575
TRG_ER_diArg_1	673	676	PF00400	0.692

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WVR7	Leishmania donovani	65%	100%