Calmodulin-binding, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Calmodulin-binding, putative

Species:

Leishmania donovani

UniProt:

A0A451EJ82_LEIDO

TriTrypDb:

LdBPK_010260.1 , LdCL_010007600 , LDHU3_01.0290

Length:

281

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005815	microtubule organizing center	2	1
GO:0005874	microtubule	6	1
GO:0005881	cytoplasmic microtubule	7	1
GO:0005930	axoneme	2	1
GO:0036064	ciliary basal body	3	1
GO:0097542	ciliary tip	2	1
GO:0099080	supramolecular complex	2	1
GO:0099081	supramolecular polymer	3	1
GO:0099512	supramolecular fiber	4	1
GO:0099513	polymeric cytoskeletal fiber	5	1
GO:0110165	cellular anatomical entity	1	3
GO:0005929	cilium	4	2
GO:0031514	motile cilium	5	2
GO:0042995	cell projection	2	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0120025	plasma membrane bounded cell projection	3	2

Expansion

Sequence features

A0A451EJ82

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A451EJ82

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	122	124	PF00675	0.626
CLV_NRD_NRD_1	182	184	PF00675	0.267
CLV_NRD_NRD_1	212	214	PF00675	0.292
CLV_NRD_NRD_1	23	25	PF00675	0.579
CLV_NRD_NRD_1	253	255	PF00675	0.288
CLV_NRD_NRD_1	32	34	PF00675	0.487
CLV_NRD_NRD_1	39	41	PF00675	0.322
CLV_PCSK_FUR_1	21	25	PF00082	0.578
CLV_PCSK_KEX2_1	122	124	PF00082	0.626
CLV_PCSK_KEX2_1	212	214	PF00082	0.342
CLV_PCSK_KEX2_1	23	25	PF00082	0.579
CLV_PCSK_KEX2_1	252	254	PF00082	0.267
CLV_PCSK_KEX2_1	32	34	PF00082	0.487
CLV_PCSK_KEX2_1	39	41	PF00082	0.322
DEG_SPOP_SBC_1	98	102	PF00917	0.605
DOC_MAPK_RevD_3	238	253	PF00069	0.399
DOC_PP2B_LxvP_1	138	141	PF13499	0.503
DOC_PP2B_LxvP_1	276	279	PF13499	0.384
DOC_USP7_MATH_1	110	114	PF00917	0.740
DOC_USP7_MATH_1	115	119	PF00917	0.729
DOC_USP7_MATH_1	131	135	PF00917	0.624
DOC_USP7_MATH_1	61	65	PF00917	0.728
DOC_USP7_MATH_1	86	90	PF00917	0.710
DOC_USP7_MATH_1	97	101	PF00917	0.696
DOC_USP7_UBL2_3	269	273	PF12436	0.345
DOC_WW_Pin1_4	111	116	PF00397	0.747
LIG_14-3-3_CanoR_1	107	115	PF00244	0.601
LIG_14-3-3_CanoR_1	202	207	PF00244	0.399
LIG_14-3-3_CanoR_1	67	75	PF00244	0.578
LIG_14-3-3_CanoR_1	88	93	PF00244	0.584
LIG_BRCT_BRCA1_1	86	90	PF00533	0.580
LIG_FHA_1	154	160	PF00498	0.533
LIG_FHA_1	244	250	PF00498	0.267
LIG_LIR_Nem_3	275	280	PF02991	0.542
LIG_SH2_NCK_1	45	49	PF00017	0.497
LIG_SH2_SRC	45	48	PF00017	0.604
LIG_SH2_STAT3	179	182	PF00017	0.285
LIG_SH2_STAT5	179	182	PF00017	0.267
LIG_SH2_STAT5	78	81	PF00017	0.588
LIG_SH3_3	138	144	PF00018	0.652
LIG_SH3_3	165	171	PF00018	0.649
LIG_SxIP_EBH_1	200	213	PF03271	0.399
LIG_TRAF2_1	215	218	PF00917	0.267
LIG_TRAF2_1	255	258	PF00917	0.333
LIG_WW_3	139	143	PF00397	0.503
MOD_CK1_1	108	114	PF00069	0.739
MOD_CK1_1	157	163	PF00069	0.735
MOD_CK2_1	212	218	PF00069	0.267
MOD_CK2_1	88	94	PF00069	0.532
MOD_GlcNHglycan	107	110	PF01048	0.673
MOD_GlcNHglycan	134	137	PF01048	0.677
MOD_GlcNHglycan	149	152	PF01048	0.636
MOD_GlcNHglycan	158	162	PF01048	0.570
MOD_GlcNHglycan	57	60	PF01048	0.709
MOD_GlcNHglycan	63	66	PF01048	0.760
MOD_GSK3_1	101	108	PF00069	0.615
MOD_GSK3_1	111	118	PF00069	0.763
MOD_GSK3_1	153	160	PF00069	0.665
MOD_GSK3_1	63	70	PF00069	0.692
MOD_GSK3_1	84	91	PF00069	0.577
MOD_GSK3_1	93	100	PF00069	0.534
MOD_N-GLC_1	98	103	PF02516	0.692
MOD_NEK2_1	38	43	PF00069	0.513
MOD_PIKK_1	243	249	PF00454	0.298
MOD_PKA_1	212	218	PF00069	0.311
MOD_PKA_2	212	218	PF00069	0.399
MOD_PKA_2	38	44	PF00069	0.541
MOD_Plk_4	202	208	PF00069	0.449
MOD_Plk_4	272	278	PF00069	0.473
MOD_ProDKin_1	111	117	PF00069	0.747
MOD_SUMO_rev_2	215	220	PF00179	0.287
TRG_ENDOCYTIC_2	45	48	PF00928	0.490
TRG_ER_diArg_1	173	176	PF00400	0.586
TRG_ER_diArg_1	21	24	PF00400	0.594
TRG_ER_diArg_1	212	214	PF00400	0.379
TRG_ER_diArg_1	252	254	PF00400	0.352
TRG_ER_diArg_1	38	40	PF00400	0.579
TRG_Pf-PMV_PEXEL_1	178	182	PF00026	0.333
TRG_Pf-PMV_PEXEL_1	224	228	PF00026	0.357
TRG_Pf-PMV_PEXEL_1	254	258	PF00026	0.401

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6N2	Leptomonas seymouri	55%	96%
A0A0S4J2X9	Bodo saltans	36%	100%
A0A1X0P2S2	Trypanosomatidae	40%	100%
A0A422NYA8	Trypanosoma rangeli	38%	100%
A4HRE7	Leishmania infantum	99%	100%
C9ZXF2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
E9AC15	Leishmania major	93%	100%
E9AJB2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	99%