BSD domain containing protein, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

BSD domain containing protein, putative

Species:

Leishmania donovani

UniProt:

A0A451EJ65_LEIDO

TriTrypDb:

LdBPK_010070.1 , LdCL_010005700 , LDHU3_01.0090

Length:

580

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A451EJ65

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A451EJ65

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	134	138	PF00656	0.558
CLV_NRD_NRD_1	140	142	PF00675	0.511
CLV_NRD_NRD_1	464	466	PF00675	0.582
CLV_PCSK_KEX2_1	428	430	PF00082	0.462
CLV_PCSK_PC1ET2_1	428	430	PF00082	0.462
CLV_PCSK_SKI1_1	142	146	PF00082	0.455
CLV_PCSK_SKI1_1	181	185	PF00082	0.491
CLV_PCSK_SKI1_1	234	238	PF00082	0.723
CLV_PCSK_SKI1_1	411	415	PF00082	0.459
CLV_PCSK_SKI1_1	448	452	PF00082	0.549
CLV_PCSK_SKI1_1	477	481	PF00082	0.482
CLV_PCSK_SKI1_1	51	55	PF00082	0.342
CLV_Separin_Metazoa	408	412	PF03568	0.516
DEG_APCC_DBOX_1	288	296	PF00400	0.315
DEG_SPOP_SBC_1	143	147	PF00917	0.467
DEG_SPOP_SBC_1	95	99	PF00917	0.743
DOC_CKS1_1	403	408	PF01111	0.464
DOC_CYCLIN_yCln2_LP_2	237	243	PF00134	0.481
DOC_CYCLIN_yCln2_LP_2	403	409	PF00134	0.452
DOC_MAPK_gen_1	29	38	PF00069	0.379
DOC_MAPK_HePTP_8	380	392	PF00069	0.411
DOC_MAPK_MEF2A_6	181	189	PF00069	0.489
DOC_MAPK_MEF2A_6	383	392	PF00069	0.477
DOC_PP1_RVXF_1	475	482	PF00149	0.391
DOC_PP2B_LxvP_1	237	240	PF13499	0.480
DOC_PP2B_LxvP_1	392	395	PF13499	0.363
DOC_PP2B_LxvP_1	75	78	PF13499	0.390
DOC_PP4_FxxP_1	38	41	PF00568	0.388
DOC_USP7_MATH_1	116	120	PF00917	0.635
DOC_USP7_MATH_1	143	147	PF00917	0.449
DOC_USP7_MATH_1	157	161	PF00917	0.306
DOC_USP7_MATH_1	259	263	PF00917	0.663
DOC_USP7_MATH_1	327	331	PF00917	0.484
DOC_USP7_MATH_1	395	399	PF00917	0.519
DOC_USP7_MATH_1	508	512	PF00917	0.615
DOC_USP7_MATH_1	86	90	PF00917	0.712
DOC_USP7_MATH_1	94	98	PF00917	0.671
DOC_WW_Pin1_4	118	123	PF00397	0.582
DOC_WW_Pin1_4	176	181	PF00397	0.508
DOC_WW_Pin1_4	247	252	PF00397	0.637
DOC_WW_Pin1_4	305	310	PF00397	0.446
DOC_WW_Pin1_4	402	407	PF00397	0.630
DOC_WW_Pin1_4	519	524	PF00397	0.669
DOC_WW_Pin1_4	530	535	PF00397	0.737
DOC_WW_Pin1_4	547	552	PF00397	0.628
DOC_WW_Pin1_4	60	65	PF00397	0.616
LIG_14-3-3_CanoR_1	141	151	PF00244	0.603
LIG_14-3-3_CanoR_1	383	389	PF00244	0.281
LIG_14-3-3_CanoR_1	562	570	PF00244	0.679
LIG_AP2alpha_2	67	69	PF02296	0.417
LIG_BIR_II_1	1	5	PF00653	0.503
LIG_BRCT_BRCA1_1	100	104	PF00533	0.581
LIG_BRCT_BRCA1_1	2	6	PF00533	0.543
LIG_BRCT_BRCA1_1	34	38	PF00533	0.356
LIG_BRCT_BRCA1_1	65	69	PF00533	0.391
LIG_Clathr_ClatBox_1	331	335	PF01394	0.458
LIG_CSL_BTD_1	38	41	PF09270	0.403
LIG_deltaCOP1_diTrp_1	275	284	PF00928	0.432
LIG_deltaCOP1_diTrp_1	324	332	PF00928	0.501
LIG_deltaCOP1_diTrp_1	362	371	PF00928	0.247
LIG_FHA_1	109	115	PF00498	0.356
LIG_FHA_1	171	177	PF00498	0.499
LIG_FHA_1	182	188	PF00498	0.379
LIG_FHA_1	200	206	PF00498	0.621
LIG_FHA_1	220	226	PF00498	0.577
LIG_FHA_1	385	391	PF00498	0.526
LIG_FHA_1	83	89	PF00498	0.590
LIG_FHA_2	121	127	PF00498	0.678
LIG_FHA_2	403	409	PF00498	0.499
LIG_FXI_DFP_1	331	335	PF00024	0.458
LIG_LIR_Apic_2	35	41	PF02991	0.375
LIG_LIR_Gen_1	283	292	PF02991	0.510
LIG_LIR_Gen_1	434	444	PF02991	0.505
LIG_LIR_Nem_3	160	164	PF02991	0.459
LIG_LIR_Nem_3	283	287	PF02991	0.438
LIG_LIR_Nem_3	363	369	PF02991	0.287
LIG_LIR_Nem_3	434	439	PF02991	0.475
LIG_LIR_Nem_3	66	72	PF02991	0.414
LIG_PDZ_Class_3	575	580	PF00595	0.592
LIG_Pex14_1	366	370	PF04695	0.289
LIG_Rb_pABgroove_1	326	334	PF01858	0.441
LIG_SH2_CRK	353	357	PF00017	0.274
LIG_SH2_STAT5	175	178	PF00017	0.533
LIG_SH2_STAT5	369	372	PF00017	0.304
LIG_SH3_3	156	162	PF00018	0.438
LIG_SH3_3	404	410	PF00018	0.363
LIG_SH3_3	486	492	PF00018	0.587
LIG_SH3_3	567	573	PF00018	0.526
LIG_SH3_3	75	81	PF00018	0.504
LIG_SUMO_SIM_anti_2	145	153	PF11976	0.329
LIG_TRAF2_1	124	127	PF00917	0.574
LIG_TRAF2_1	273	276	PF00917	0.569
LIG_TRAF2_1	573	576	PF00917	0.539
LIG_TRFH_1	353	357	PF08558	0.274
LIG_WW_3	522	526	PF00397	0.724
MOD_CDK_SPK_2	176	181	PF00069	0.350
MOD_CDK_SPxK_1	519	525	PF00069	0.749
MOD_CDK_SPxxK_3	547	554	PF00069	0.590
MOD_CK1_1	179	185	PF00069	0.484
MOD_CK1_1	209	215	PF00069	0.537
MOD_CK1_1	232	238	PF00069	0.553
MOD_CK1_1	470	476	PF00069	0.385
MOD_CK1_1	89	95	PF00069	0.686
MOD_CK1_1	97	103	PF00069	0.631
MOD_CK2_1	120	126	PF00069	0.667
MOD_CK2_1	305	311	PF00069	0.406
MOD_CK2_1	402	408	PF00069	0.564
MOD_CK2_1	470	476	PF00069	0.514
MOD_CK2_1	541	547	PF00069	0.697
MOD_GlcNHglycan	100	103	PF01048	0.671
MOD_GlcNHglycan	165	168	PF01048	0.452
MOD_GlcNHglycan	2	5	PF01048	0.540
MOD_GlcNHglycan	234	237	PF01048	0.661
MOD_GlcNHglycan	344	347	PF01048	0.350
MOD_GlcNHglycan	42	45	PF01048	0.598
MOD_GlcNHglycan	511	514	PF01048	0.727
MOD_GlcNHglycan	543	546	PF01048	0.734
MOD_GlcNHglycan	557	560	PF01048	0.645
MOD_GlcNHglycan	88	91	PF01048	0.701
MOD_GSK3_1	116	123	PF00069	0.524
MOD_GSK3_1	181	188	PF00069	0.487
MOD_GSK3_1	206	213	PF00069	0.518
MOD_GSK3_1	247	254	PF00069	0.721
MOD_GSK3_1	467	474	PF00069	0.486
MOD_GSK3_1	530	537	PF00069	0.727
MOD_GSK3_1	541	548	PF00069	0.686
MOD_GSK3_1	82	89	PF00069	0.595
MOD_GSK3_1	94	101	PF00069	0.649
MOD_N-GLC_1	244	249	PF02516	0.594
MOD_N-GLC_1	401	406	PF02516	0.464
MOD_N-GLC_1	86	91	PF02516	0.538
MOD_NEK2_1	170	175	PF00069	0.462
MOD_NEK2_1	207	212	PF00069	0.534
MOD_NEK2_1	219	224	PF00069	0.576
MOD_NEK2_1	295	300	PF00069	0.496
MOD_NEK2_1	517	522	PF00069	0.564
MOD_NEK2_1	58	63	PF00069	0.454
MOD_NEK2_2	12	17	PF00069	0.509
MOD_NEK2_2	229	234	PF00069	0.472
MOD_NEK2_2	327	332	PF00069	0.491
MOD_NEK2_2	395	400	PF00069	0.449
MOD_PIKK_1	452	458	PF00454	0.539
MOD_PIKK_1	517	523	PF00454	0.785
MOD_PIKK_1	562	568	PF00454	0.683
MOD_PKA_2	12	18	PF00069	0.460
MOD_PKA_2	229	235	PF00069	0.604
MOD_Plk_1	303	309	PF00069	0.490
MOD_Plk_1	361	367	PF00069	0.417
MOD_Plk_1	468	474	PF00069	0.381
MOD_Plk_4	12	18	PF00069	0.441
MOD_Plk_4	283	289	PF00069	0.483
MOD_Plk_4	327	333	PF00069	0.441
MOD_Plk_4	361	367	PF00069	0.400
MOD_Plk_4	384	390	PF00069	0.312
MOD_ProDKin_1	118	124	PF00069	0.589
MOD_ProDKin_1	176	182	PF00069	0.499
MOD_ProDKin_1	247	253	PF00069	0.637
MOD_ProDKin_1	305	311	PF00069	0.438
MOD_ProDKin_1	402	408	PF00069	0.624
MOD_ProDKin_1	519	525	PF00069	0.672
MOD_ProDKin_1	530	536	PF00069	0.739
MOD_ProDKin_1	547	553	PF00069	0.626
MOD_ProDKin_1	60	66	PF00069	0.613
MOD_SUMO_for_1	360	363	PF00179	0.264
TRG_DiLeu_BaEn_1	283	288	PF01217	0.389
TRG_ENDOCYTIC_2	353	356	PF00928	0.274
TRG_Pf-PMV_PEXEL_1	411	415	PF00026	0.495
TRG_Pf-PMV_PEXEL_1	56	60	PF00026	0.414

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILJ7	Leptomonas seymouri	48%	93%
A0A0S4JIQ1	Bodo saltans	29%	76%
A0A1X0P2Y2	Trypanosomatidae	31%	100%
A0A3R7LAJ1	Trypanosoma rangeli	31%	100%
A4H322	Leishmania braziliensis	70%	100%
A4HRC8	Leishmania infantum	99%	100%
C9ZXG8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	100%
E9ABZ6	Leishmania major	85%	100%
E9AJ93	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	99%
V5AME8	Trypanosoma cruzi	31%	100%