LeishMANIAdb
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Tartrate-sensitive acid phosphatase acp-3.2, putative

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Tartrate-sensitive acid phosphatase acp-3.2, putative
Gene product:
histidine secretory acid phosphatase, putative (fragment)
Species:
Leishmania donovani
UniProt:
A0A3S7XC60_LEIDO
TriTrypDb:
LdBPK_366770.1 , LdCL_360076000 , LDHU3_36.8990
Length:
1026

Annotations

LeishMANIAdb annotations

An extensively expanded family of exophosphatase enzymes presumed to be active at acidic pH

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 9
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 yes yes: 1, no: 0
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7XC60
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XC60

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 154 158 PF00656 0.275
CLV_C14_Caspase3-7 320 324 PF00656 0.288
CLV_C14_Caspase3-7 406 410 PF00656 0.342
CLV_NRD_NRD_1 1011 1013 PF00675 0.537
CLV_NRD_NRD_1 1019 1021 PF00675 0.532
CLV_NRD_NRD_1 376 378 PF00675 0.262
CLV_NRD_NRD_1 855 857 PF00675 0.486
CLV_NRD_NRD_1 863 865 PF00675 0.485
CLV_NRD_NRD_1 871 873 PF00675 0.492
CLV_NRD_NRD_1 879 881 PF00675 0.516
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Homologs

ProteinTaxonomySequence identityCoverage
P13821 PLAFW 25% 100%
Q86X53 HUMAN 31% 100%
Q9JM99 MOUSE 27% 97%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS