L6202.3-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

l6202.3-like protein

Species:

Leishmania donovani

UniProt:

A0A3S7XC59_LEIDO

TriTrypDb:

LdBPK_366260.1 , LdCL_360070000 , LDHU3_36.8300

Length:

851

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7XC59

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XC59

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	160	164	PF00656	0.487
CLV_C14_Caspase3-7	250	254	PF00656	0.493
CLV_C14_Caspase3-7	313	317	PF00656	0.527
CLV_C14_Caspase3-7	841	845	PF00656	0.522
CLV_MEL_PAP_1	528	534	PF00089	0.493
CLV_NRD_NRD_1	186	188	PF00675	0.529
CLV_NRD_NRD_1	232	234	PF00675	0.550
CLV_NRD_NRD_1	245	247	PF00675	0.386
CLV_NRD_NRD_1	274	276	PF00675	0.499
CLV_NRD_NRD_1	301	303	PF00675	0.471
CLV_NRD_NRD_1	477	479	PF00675	0.645
CLV_NRD_NRD_1	530	532	PF00675	0.510
CLV_NRD_NRD_1	614	616	PF00675	0.559
CLV_NRD_NRD_1	618	620	PF00675	0.537
CLV_NRD_NRD_1	691	693	PF00675	0.593
CLV_NRD_NRD_1	736	738	PF00675	0.655
CLV_NRD_NRD_1	746	748	PF00675	0.577
CLV_NRD_NRD_1	755	757	PF00675	0.522
CLV_PCSK_FUR_1	230	234	PF00082	0.546
CLV_PCSK_FUR_1	692	696	PF00082	0.573
CLV_PCSK_KEX2_1	185	187	PF00082	0.540
CLV_PCSK_KEX2_1	232	234	PF00082	0.550
CLV_PCSK_KEX2_1	245	247	PF00082	0.386
CLV_PCSK_KEX2_1	274	276	PF00082	0.517
CLV_PCSK_KEX2_1	301	303	PF00082	0.448
CLV_PCSK_KEX2_1	477	479	PF00082	0.647
CLV_PCSK_KEX2_1	530	532	PF00082	0.509
CLV_PCSK_KEX2_1	614	616	PF00082	0.526
CLV_PCSK_KEX2_1	620	622	PF00082	0.459
CLV_PCSK_KEX2_1	691	693	PF00082	0.641
CLV_PCSK_KEX2_1	694	696	PF00082	0.661
CLV_PCSK_KEX2_1	704	706	PF00082	0.601
CLV_PCSK_KEX2_1	736	738	PF00082	0.655
CLV_PCSK_KEX2_1	746	748	PF00082	0.577
CLV_PCSK_KEX2_1	755	757	PF00082	0.522
CLV_PCSK_PC1ET2_1	185	187	PF00082	0.480
CLV_PCSK_PC1ET2_1	620	622	PF00082	0.461
CLV_PCSK_PC1ET2_1	694	696	PF00082	0.660
CLV_PCSK_PC1ET2_1	704	706	PF00082	0.588
CLV_PCSK_PC7_1	182	188	PF00082	0.508
CLV_PCSK_PC7_1	732	738	PF00082	0.646
CLV_PCSK_SKI1_1	182	186	PF00082	0.473
CLV_PCSK_SKI1_1	260	264	PF00082	0.462
CLV_PCSK_SKI1_1	293	297	PF00082	0.555
CLV_PCSK_SKI1_1	301	305	PF00082	0.608
CLV_PCSK_SKI1_1	327	331	PF00082	0.506
CLV_PCSK_SKI1_1	33	37	PF00082	0.632
CLV_PCSK_SKI1_1	407	411	PF00082	0.593
CLV_PCSK_SKI1_1	505	509	PF00082	0.607
CLV_PCSK_SKI1_1	694	698	PF00082	0.715
CLV_PCSK_SKI1_1	705	709	PF00082	0.709
CLV_PCSK_SKI1_1	747	751	PF00082	0.684
DEG_SPOP_SBC_1	428	432	PF00917	0.604
DEG_SPOP_SBC_1	667	671	PF00917	0.601
DOC_CDC14_PxL_1	773	781	PF14671	0.587
DOC_CKS1_1	759	764	PF01111	0.700
DOC_CYCLIN_RxL_1	182	193	PF00134	0.550
DOC_CYCLIN_RxL_1	298	307	PF00134	0.466
DOC_MAPK_gen_1	182	190	PF00069	0.549
DOC_MAPK_gen_1	337	346	PF00069	0.589
DOC_MAPK_gen_1	383	391	PF00069	0.532
DOC_MAPK_gen_1	530	536	PF00069	0.567
DOC_MAPK_gen_1	582	590	PF00069	0.593
DOC_MAPK_MEF2A_6	337	346	PF00069	0.557
DOC_MAPK_MEF2A_6	385	393	PF00069	0.532
DOC_MAPK_MEF2A_6	59	68	PF00069	0.577
DOC_PP1_RVXF_1	258	264	PF00149	0.472
DOC_PP2B_LxvP_1	843	846	PF13499	0.518
DOC_PP4_MxPP_1	699	702	PF00568	0.522
DOC_USP7_MATH_1	197	201	PF00917	0.507
DOC_USP7_MATH_1	335	339	PF00917	0.539
DOC_USP7_MATH_1	374	378	PF00917	0.608
DOC_USP7_MATH_1	4	8	PF00917	0.710
DOC_USP7_MATH_1	421	425	PF00917	0.612
DOC_USP7_MATH_1	428	432	PF00917	0.579
DOC_USP7_MATH_1	50	54	PF00917	0.530
DOC_USP7_MATH_1	509	513	PF00917	0.630
DOC_USP7_MATH_1	538	542	PF00917	0.542
DOC_USP7_MATH_1	684	688	PF00917	0.629
DOC_USP7_MATH_1	720	724	PF00917	0.605
DOC_USP7_MATH_1	788	792	PF00917	0.754
DOC_USP7_MATH_1	800	804	PF00917	0.640
DOC_USP7_UBL2_3	694	698	PF12436	0.651
DOC_USP7_UBL2_3	704	708	PF12436	0.580
DOC_WW_Pin1_4	357	362	PF00397	0.661
DOC_WW_Pin1_4	424	429	PF00397	0.661
DOC_WW_Pin1_4	675	680	PF00397	0.714
DOC_WW_Pin1_4	707	712	PF00397	0.711
DOC_WW_Pin1_4	758	763	PF00397	0.612
LIG_14-3-3_CanoR_1	10	18	PF00244	0.576
LIG_14-3-3_CanoR_1	186	191	PF00244	0.577
LIG_14-3-3_CanoR_1	222	227	PF00244	0.528
LIG_14-3-3_CanoR_1	245	249	PF00244	0.524
LIG_14-3-3_CanoR_1	355	359	PF00244	0.658
LIG_14-3-3_CanoR_1	444	450	PF00244	0.613
LIG_14-3-3_CanoR_1	45	54	PF00244	0.511
LIG_14-3-3_CanoR_1	457	465	PF00244	0.510
LIG_14-3-3_CanoR_1	505	514	PF00244	0.558
LIG_14-3-3_CanoR_1	537	543	PF00244	0.551
LIG_14-3-3_CanoR_1	546	556	PF00244	0.472
LIG_14-3-3_CanoR_1	73	79	PF00244	0.533
LIG_14-3-3_CanoR_1	756	762	PF00244	0.763
LIG_Actin_WH2_2	442	459	PF00022	0.510
LIG_Actin_WH2_2	528	545	PF00022	0.502
LIG_APCC_ABBA_1	832	837	PF00400	0.521
LIG_BIR_II_1	1	5	PF00653	0.621
LIG_BIR_III_3	1	5	PF00653	0.584
LIG_CaM_IQ_9	174	189	PF13499	0.506
LIG_FHA_1	13	19	PF00498	0.599
LIG_FHA_1	144	150	PF00498	0.542
LIG_FHA_1	328	334	PF00498	0.531
LIG_FHA_1	408	414	PF00498	0.681
LIG_FHA_1	477	483	PF00498	0.459
LIG_FHA_1	520	526	PF00498	0.589
LIG_FHA_1	548	554	PF00498	0.671
LIG_FHA_1	565	571	PF00498	0.397
LIG_FHA_1	668	674	PF00498	0.562
LIG_FHA_1	708	714	PF00498	0.694
LIG_FHA_1	728	734	PF00498	0.626
LIG_FHA_1	748	754	PF00498	0.718
LIG_FHA_1	759	765	PF00498	0.564
LIG_FHA_1	828	834	PF00498	0.603
LIG_FHA_2	136	142	PF00498	0.406
LIG_FHA_2	223	229	PF00498	0.616
LIG_FHA_2	245	251	PF00498	0.550
LIG_FHA_2	311	317	PF00498	0.523
LIG_FHA_2	758	764	PF00498	0.676
LIG_LIR_Gen_1	168	177	PF02991	0.468
LIG_LIR_Gen_1	573	581	PF02991	0.481
LIG_LIR_Nem_3	168	173	PF02991	0.473
LIG_LIR_Nem_3	573	578	PF02991	0.596
LIG_LIR_Nem_3	771	776	PF02991	0.585
LIG_LYPXL_S_1	772	776	PF13949	0.522
LIG_LYPXL_yS_3	773	776	PF13949	0.523
LIG_MYND_1	646	650	PF01753	0.579
LIG_MYND_3	776	780	PF01753	0.588
LIG_SH2_STAP1	470	474	PF00017	0.559
LIG_SH2_STAP1	785	789	PF00017	0.546
LIG_SH2_STAT3	120	123	PF00017	0.527
LIG_SH2_STAT3	470	473	PF00017	0.559
LIG_SH2_STAT5	203	206	PF00017	0.666
LIG_SH3_3	355	361	PF00018	0.654
LIG_SH3_3	362	368	PF00018	0.641
LIG_SH3_3	673	679	PF00018	0.525
LIG_SH3_3	771	777	PF00018	0.524
LIG_Sin3_3	682	689	PF02671	0.616
LIG_SUMO_SIM_anti_2	763	769	PF11976	0.642
LIG_SUMO_SIM_par_1	61	67	PF11976	0.490
LIG_TRAF2_1	138	141	PF00917	0.492
LIG_TRAF2_1	24	27	PF00917	0.550
LIG_TRAF2_1	247	250	PF00917	0.486
LIG_TRAF2_1	370	373	PF00917	0.644
LIG_TRAF2_1	817	820	PF00917	0.692
MOD_CK1_1	165	171	PF00069	0.536
MOD_CK1_1	357	363	PF00069	0.756
MOD_CK1_1	401	407	PF00069	0.577
MOD_CK1_1	424	430	PF00069	0.649
MOD_CK1_1	431	437	PF00069	0.631
MOD_CK1_1	445	451	PF00069	0.447
MOD_CK1_1	452	458	PF00069	0.525
MOD_CK1_1	48	54	PF00069	0.531
MOD_CK1_1	541	547	PF00069	0.508
MOD_CK1_1	725	731	PF00069	0.626
MOD_CK1_1	735	741	PF00069	0.614
MOD_CK1_1	77	83	PF00069	0.506
MOD_CK1_1	791	797	PF00069	0.604
MOD_CK1_1	826	832	PF00069	0.636
MOD_CK2_1	135	141	PF00069	0.404
MOD_CK2_1	165	171	PF00069	0.576
MOD_CK2_1	222	228	PF00069	0.571
MOD_CK2_1	244	250	PF00069	0.551
MOD_CK2_1	284	290	PF00069	0.492
MOD_CK2_1	335	341	PF00069	0.465
MOD_CK2_1	38	44	PF00069	0.600
MOD_CK2_1	66	72	PF00069	0.502
MOD_GlcNHglycan	18	21	PF01048	0.570
MOD_GlcNHglycan	253	256	PF01048	0.556
MOD_GlcNHglycan	417	420	PF01048	0.593
MOD_GlcNHglycan	423	426	PF01048	0.557
MOD_GlcNHglycan	438	441	PF01048	0.485
MOD_GlcNHglycan	670	673	PF01048	0.726
MOD_GlcNHglycan	790	793	PF01048	0.547
MOD_GlcNHglycan	796	799	PF01048	0.524
MOD_GlcNHglycan	803	806	PF01048	0.675
MOD_GlcNHglycan	808	812	PF01048	0.753
MOD_GSK3_1	12	19	PF00069	0.574
MOD_GSK3_1	186	193	PF00069	0.477
MOD_GSK3_1	218	225	PF00069	0.412
MOD_GSK3_1	34	41	PF00069	0.641
MOD_GSK3_1	357	364	PF00069	0.746
MOD_GSK3_1	4	11	PF00069	0.707
MOD_GSK3_1	424	431	PF00069	0.634
MOD_GSK3_1	445	452	PF00069	0.666
MOD_GSK3_1	501	508	PF00069	0.549
MOD_GSK3_1	541	548	PF00069	0.576
MOD_GSK3_1	552	559	PF00069	0.484
MOD_GSK3_1	636	643	PF00069	0.601
MOD_GSK3_1	654	661	PF00069	0.705
MOD_GSK3_1	703	710	PF00069	0.664
MOD_GSK3_1	735	742	PF00069	0.604
MOD_GSK3_1	747	754	PF00069	0.807
MOD_GSK3_1	790	797	PF00069	0.606
MOD_GSK3_1	823	830	PF00069	0.600
MOD_N-GLC_1	216	221	PF02516	0.464
MOD_N-GLC_1	526	531	PF02516	0.536
MOD_N-GLC_1	667	672	PF02516	0.597
MOD_N-GLC_1	739	744	PF02516	0.582
MOD_NEK2_1	135	140	PF00069	0.405
MOD_NEK2_1	190	195	PF00069	0.553
MOD_NEK2_1	34	39	PF00069	0.623
MOD_NEK2_1	389	394	PF00069	0.584
MOD_NEK2_1	456	461	PF00069	0.517
MOD_NEK2_1	634	639	PF00069	0.598
MOD_NEK2_2	104	109	PF00069	0.515
MOD_NEK2_2	145	150	PF00069	0.360
MOD_NEK2_2	538	543	PF00069	0.579
MOD_NEK2_2	768	773	PF00069	0.554
MOD_PIKK_1	310	316	PF00454	0.520
MOD_PIKK_1	34	40	PF00454	0.522
MOD_PIKK_1	359	365	PF00454	0.706
MOD_PIKK_1	476	482	PF00454	0.514
MOD_PIKK_1	48	54	PF00454	0.553
MOD_PIKK_1	509	515	PF00454	0.567
MOD_PIKK_1	658	664	PF00454	0.594
MOD_PIKK_1	739	745	PF00454	0.721
MOD_PK_1	582	588	PF00069	0.516
MOD_PKA_1	186	192	PF00069	0.516
MOD_PKA_2	186	192	PF00069	0.573
MOD_PKA_2	244	250	PF00069	0.520
MOD_PKA_2	354	360	PF00069	0.652
MOD_PKA_2	452	458	PF00069	0.578
MOD_PKA_2	476	482	PF00069	0.573
MOD_PKA_2	545	551	PF00069	0.517
MOD_PKA_2	735	741	PF00069	0.587
MOD_PKA_2	754	760	PF00069	0.580
MOD_PKA_2	838	844	PF00069	0.524
MOD_PKA_2	9	15	PF00069	0.578
MOD_PKB_1	652	660	PF00069	0.560
MOD_PKB_1	737	745	PF00069	0.583
MOD_Plk_1	165	171	PF00069	0.536
MOD_Plk_1	197	203	PF00069	0.510
MOD_Plk_1	582	588	PF00069	0.531
MOD_Plk_1	590	596	PF00069	0.494
MOD_Plk_4	165	171	PF00069	0.566
MOD_Plk_4	50	56	PF00069	0.643
MOD_Plk_4	722	728	PF00069	0.682
MOD_Plk_4	768	774	PF00069	0.597
MOD_Plk_4	838	844	PF00069	0.649
MOD_ProDKin_1	357	363	PF00069	0.662
MOD_ProDKin_1	424	430	PF00069	0.660
MOD_ProDKin_1	675	681	PF00069	0.712
MOD_ProDKin_1	707	713	PF00069	0.712
MOD_ProDKin_1	758	764	PF00069	0.612
MOD_SUMO_for_1	395	398	PF00179	0.602
MOD_SUMO_rev_2	458	466	PF00179	0.596
MOD_SUMO_rev_2	486	491	PF00179	0.497
TRG_AP2beta_CARGO_1	573	582	PF09066	0.543
TRG_DiLeu_BaLyEn_6	299	304	PF01217	0.502
TRG_DiLeu_BaLyEn_6	566	571	PF01217	0.473
TRG_DiLeu_BaLyEn_6	644	649	PF01217	0.621
TRG_ENDOCYTIC_2	773	776	PF00928	0.585
TRG_ER_diArg_1	186	188	PF00400	0.529
TRG_ER_diArg_1	230	233	PF00400	0.548
TRG_ER_diArg_1	274	277	PF00400	0.501
TRG_ER_diArg_1	300	302	PF00400	0.471
TRG_ER_diArg_1	336	339	PF00400	0.586
TRG_ER_diArg_1	383	386	PF00400	0.560
TRG_ER_diArg_1	530	532	PF00400	0.511
TRG_ER_diArg_1	614	616	PF00400	0.529
TRG_ER_diArg_1	618	621	PF00400	0.499
TRG_ER_diArg_1	736	739	PF00400	0.592
TRG_NES_CRM1_1	568	583	PF08389	0.542
TRG_NLS_MonoExtC_3	618	624	PF00514	0.553
TRG_NLS_MonoExtN_4	182	189	PF00514	0.510
TRG_Pf-PMV_PEXEL_1	186	191	PF00026	0.555
TRG_Pf-PMV_PEXEL_1	224	228	PF00026	0.553
TRG_Pf-PMV_PEXEL_1	301	305	PF00026	0.573
TRG_Pf-PMV_PEXEL_1	45	49	PF00026	0.593
TRG_Pf-PMV_PEXEL_1	569	573	PF00026	0.494

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFI1	Leptomonas seymouri	40%	88%
A4HQB9	Leishmania braziliensis	57%	100%
A4IE13	Leishmania infantum	100%	100%
E9AU35	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	100%
Q4Q0G0	Leishmania major	87%	100%