LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

RING-type E3 ubiquitin transferase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
RING-type E3 ubiquitin transferase
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7XBY8_LEIDO
TriTrypDb:
LdBPK_365570.1 , LdCL_360063000 , LDHU3_36.7400
Length:
863

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7XBY8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XBY8

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 483 487 PF00656 0.489
CLV_C14_Caspase3-7 777 781 PF00656 0.557
CLV_NRD_NRD_1 124 126 PF00675 0.426
CLV_NRD_NRD_1 158 160 PF00675 0.665
CLV_NRD_NRD_1 251 253 PF00675 0.493
CLV_NRD_NRD_1 297 299 PF00675 0.509
CLV_NRD_NRD_1 429 431 PF00675 0.555
CLV_NRD_NRD_1 525 527 PF00675 0.508
CLV_NRD_NRD_1 53 55 PF00675 0.480
CLV_NRD_NRD_1 560 562 PF00675 0.486
Previous12345…25Next

Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1IJ64 Leptomonas seymouri 53% 100%
A0A1X0P393 Trypanosomatidae 34% 100%
A0A422NT20 Trypanosoma rangeli 35% 100%
A4HQ48 Leishmania braziliensis 78% 99%
A4IC76 Leishmania infantum 100% 100%
D0A8R1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
E9ATW8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 94% 100%
Q4Q0M8 Leishmania major 93% 100%
Previous1Next

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS