LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7XBV2_LEIDO
TriTrypDb:
LdBPK_365990.1 * , LdCL_360067300 , LDHU3_36.7910
Length:
727

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7XBV2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XBV2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 487 491 PF00656 0.643
CLV_NRD_NRD_1 102 104 PF00675 0.843
CLV_NRD_NRD_1 122 124 PF00675 0.543
CLV_NRD_NRD_1 296 298 PF00675 0.806
CLV_NRD_NRD_1 309 311 PF00675 0.620
CLV_NRD_NRD_1 348 350 PF00675 0.740
CLV_NRD_NRD_1 658 660 PF00675 0.647
CLV_PCSK_FUR_1 100 104 PF00082 0.787
CLV_PCSK_KEX2_1 100 102 PF00082 0.830
CLV_PCSK_KEX2_1 122 124 PF00082 0.757
CLV_PCSK_KEX2_1 296 298 PF00082 0.803
CLV_PCSK_KEX2_1 336 338 PF00082 0.752
CLV_PCSK_KEX2_1 348 350 PF00082 0.727
CLV_PCSK_KEX2_1 384 386 PF00082 0.713
CLV_PCSK_KEX2_1 658 660 PF00082 0.647
CLV_PCSK_PC1ET2_1 336 338 PF00082 0.752
CLV_PCSK_PC1ET2_1 384 386 PF00082 0.713
CLV_PCSK_PC7_1 292 298 PF00082 0.728
CLV_PCSK_SKI1_1 203 207 PF00082 0.642
CLV_PCSK_SKI1_1 284 288 PF00082 0.681
CLV_PCSK_SKI1_1 73 77 PF00082 0.694
CLV_Separin_Metazoa 16 20 PF03568 0.564
DEG_Nend_Nbox_1 1 3 PF02207 0.629
DEG_SCF_FBW7_1 243 248 PF00400 0.722
DEG_SPOP_SBC_1 124 128 PF00917 0.738
DEG_SPOP_SBC_1 174 178 PF00917 0.690
DEG_SPOP_SBC_1 476 480 PF00917 0.839
DEG_SPOP_SBC_1 576 580 PF00917 0.740
DOC_CYCLIN_yClb5_NLxxxL_5 560 567 PF00134 0.743
DOC_PP4_FxxP_1 587 590 PF00568 0.808
DOC_PP4_FxxP_1 675 678 PF00568 0.579
DOC_PP4_MxPP_1 676 679 PF00568 0.670
DOC_USP7_MATH_1 118 122 PF00917 0.850
DOC_USP7_MATH_1 124 128 PF00917 0.781
DOC_USP7_MATH_1 135 139 PF00917 0.588
DOC_USP7_MATH_1 174 178 PF00917 0.730
DOC_USP7_MATH_1 270 274 PF00917 0.778
DOC_USP7_MATH_1 282 286 PF00917 0.621
DOC_USP7_MATH_1 290 294 PF00917 0.516
DOC_USP7_MATH_1 321 325 PF00917 0.839
DOC_USP7_MATH_1 326 330 PF00917 0.757
DOC_USP7_MATH_1 351 355 PF00917 0.627
DOC_USP7_MATH_1 380 384 PF00917 0.797
DOC_USP7_MATH_1 398 402 PF00917 0.512
DOC_USP7_MATH_1 414 418 PF00917 0.629
DOC_USP7_MATH_1 446 450 PF00917 0.713
DOC_USP7_MATH_1 476 480 PF00917 0.806
DOC_USP7_MATH_1 497 501 PF00917 0.576
DOC_USP7_MATH_1 538 542 PF00917 0.616
DOC_USP7_MATH_1 56 60 PF00917 0.787
DOC_USP7_MATH_1 569 573 PF00917 0.814
DOC_USP7_MATH_1 576 580 PF00917 0.712
DOC_USP7_MATH_1 633 637 PF00917 0.790
DOC_USP7_MATH_1 94 98 PF00917 0.681
DOC_WW_Pin1_4 129 134 PF00397 0.803
DOC_WW_Pin1_4 175 180 PF00397 0.840
DOC_WW_Pin1_4 184 189 PF00397 0.657
DOC_WW_Pin1_4 241 246 PF00397 0.748
DOC_WW_Pin1_4 266 271 PF00397 0.770
DOC_WW_Pin1_4 278 283 PF00397 0.628
DOC_WW_Pin1_4 286 291 PF00397 0.520
DOC_WW_Pin1_4 305 310 PF00397 0.578
DOC_WW_Pin1_4 337 342 PF00397 0.837
DOC_WW_Pin1_4 376 381 PF00397 0.728
DOC_WW_Pin1_4 418 423 PF00397 0.813
DOC_WW_Pin1_4 440 445 PF00397 0.692
DOC_WW_Pin1_4 467 472 PF00397 0.740
DOC_WW_Pin1_4 501 506 PF00397 0.640
DOC_WW_Pin1_4 58 63 PF00397 0.690
DOC_WW_Pin1_4 626 631 PF00397 0.654
DOC_WW_Pin1_4 710 715 PF00397 0.758
DOC_WW_Pin1_4 719 724 PF00397 0.714
LIG_14-3-3_CanoR_1 123 133 PF00244 0.748
LIG_14-3-3_CanoR_1 144 152 PF00244 0.727
LIG_14-3-3_CanoR_1 164 173 PF00244 0.563
LIG_14-3-3_CanoR_1 175 179 PF00244 0.695
LIG_14-3-3_CanoR_1 26 32 PF00244 0.744
LIG_14-3-3_CanoR_1 284 290 PF00244 0.678
LIG_14-3-3_CanoR_1 296 300 PF00244 0.661
LIG_14-3-3_CanoR_1 385 389 PF00244 0.697
LIG_14-3-3_CanoR_1 41 47 PF00244 0.597
LIG_14-3-3_CanoR_1 515 521 PF00244 0.681
LIG_14-3-3_CanoR_1 624 630 PF00244 0.846
LIG_14-3-3_CanoR_1 670 679 PF00244 0.682
LIG_BRCT_BRCA1_1 521 525 PF00533 0.507
LIG_FHA_1 161 167 PF00498 0.717
LIG_FHA_1 187 193 PF00498 0.785
LIG_FHA_1 246 252 PF00498 0.679
LIG_FHA_1 433 439 PF00498 0.733
LIG_FHA_1 464 470 PF00498 0.651
LIG_FHA_1 687 693 PF00498 0.696
LIG_FHA_2 229 235 PF00498 0.821
LIG_FHA_2 480 486 PF00498 0.847
LIG_Integrin_RGD_1 551 553 PF01839 0.614
LIG_LIR_Apic_2 416 422 PF02991 0.651
LIG_LIR_Apic_2 673 678 PF02991 0.596
LIG_LIR_LC3C_4 187 192 PF02991 0.637
LIG_LIR_Nem_3 602 608 PF02991 0.831
LIG_LIR_Nem_3 70 75 PF02991 0.709
LIG_LYPXL_SIV_4 641 649 PF13949 0.730
LIG_PCNA_yPIPBox_3 495 507 PF02747 0.717
LIG_Pex14_2 525 529 PF04695 0.500
LIG_SH2_CRK 412 416 PF00017 0.800
LIG_SH2_CRK 419 423 PF00017 0.702
LIG_SH2_NCK_1 419 423 PF00017 0.721
LIG_SH2_NCK_1 642 646 PF00017 0.632
LIG_SH2_STAP1 608 612 PF00017 0.840
LIG_SH2_STAT3 634 637 PF00017 0.774
LIG_SH2_STAT3 647 650 PF00017 0.650
LIG_SH2_STAT5 299 302 PF00017 0.673
LIG_SH2_STAT5 634 637 PF00017 0.611
LIG_SH3_3 198 204 PF00018 0.570
LIG_SH3_3 303 309 PF00018 0.762
LIG_SH3_3 627 633 PF00018 0.673
LIG_SUMO_SIM_anti_2 189 194 PF11976 0.651
LIG_SUMO_SIM_par_1 145 155 PF11976 0.633
LIG_SUMO_SIM_par_1 516 522 PF11976 0.688
LIG_SxIP_EBH_1 495 507 PF03271 0.581
LIG_TRAF2_1 231 234 PF00917 0.873
LIG_TRAF2_1 342 345 PF00917 0.845
LIG_TRAF2_1 471 474 PF00917 0.672
LIG_TRAF2_1 482 485 PF00917 0.845
MOD_CDC14_SPxK_1 281 284 PF00782 0.715
MOD_CDC14_SPxK_1 289 292 PF00782 0.688
MOD_CDC14_SPxK_1 308 311 PF00782 0.580
MOD_CDC14_SPxK_1 504 507 PF00782 0.719
MOD_CDK_SPK_2 305 310 PF00069 0.765
MOD_CDK_SPK_2 58 63 PF00069 0.690
MOD_CDK_SPxK_1 266 272 PF00069 0.774
MOD_CDK_SPxK_1 278 284 PF00069 0.630
MOD_CDK_SPxK_1 286 292 PF00069 0.521
MOD_CDK_SPxK_1 305 311 PF00069 0.579
MOD_CDK_SPxK_1 501 507 PF00069 0.795
MOD_CDK_SPxxK_3 305 312 PF00069 0.768
MOD_CDK_SPxxK_3 710 717 PF00069 0.723
MOD_CK1_1 126 132 PF00069 0.742
MOD_CK1_1 142 148 PF00069 0.591
MOD_CK1_1 177 183 PF00069 0.678
MOD_CK1_1 186 192 PF00069 0.659
MOD_CK1_1 249 255 PF00069 0.653
MOD_CK1_1 285 291 PF00069 0.673
MOD_CK1_1 331 337 PF00069 0.694
MOD_CK1_1 355 361 PF00069 0.627
MOD_CK1_1 362 368 PF00069 0.624
MOD_CK1_1 379 385 PF00069 0.667
MOD_CK1_1 397 403 PF00069 0.528
MOD_CK1_1 413 419 PF00069 0.521
MOD_CK1_1 442 448 PF00069 0.759
MOD_CK1_1 467 473 PF00069 0.726
MOD_CK1_1 477 483 PF00069 0.635
MOD_CK1_1 519 525 PF00069 0.679
MOD_CK1_1 54 60 PF00069 0.715
MOD_CK1_1 556 562 PF00069 0.665
MOD_CK1_1 572 578 PF00069 0.642
MOD_CK1_1 579 585 PF00069 0.618
MOD_CK1_1 611 617 PF00069 0.824
MOD_CK1_1 626 632 PF00069 0.604
MOD_CK1_1 643 649 PF00069 0.610
MOD_CK1_1 662 668 PF00069 0.820
MOD_CK1_1 686 692 PF00069 0.769
MOD_CK1_1 715 721 PF00069 0.823
MOD_CK2_1 228 234 PF00069 0.849
MOD_CK2_1 288 294 PF00069 0.800
MOD_CK2_1 337 343 PF00069 0.834
MOD_CK2_1 478 484 PF00069 0.756
MOD_CK2_1 68 74 PF00069 0.644
MOD_Cter_Amidation 98 101 PF01082 0.706
MOD_GlcNHglycan 13 16 PF01048 0.652
MOD_GlcNHglycan 236 239 PF01048 0.643
MOD_GlcNHglycan 284 287 PF01048 0.653
MOD_GlcNHglycan 328 331 PF01048 0.798
MOD_GlcNHglycan 396 399 PF01048 0.629
MOD_GlcNHglycan 412 415 PF01048 0.705
MOD_GlcNHglycan 416 419 PF01048 0.645
MOD_GlcNHglycan 448 451 PF01048 0.748
MOD_GlcNHglycan 466 469 PF01048 0.631
MOD_GlcNHglycan 526 529 PF01048 0.692
MOD_GlcNHglycan 555 558 PF01048 0.642
MOD_GlcNHglycan 573 577 PF01048 0.596
MOD_GlcNHglycan 58 61 PF01048 0.814
MOD_GlcNHglycan 610 613 PF01048 0.763
MOD_GlcNHglycan 698 701 PF01048 0.749
MOD_GSK3_1 124 131 PF00069 0.720
MOD_GSK3_1 135 142 PF00069 0.766
MOD_GSK3_1 148 155 PF00069 0.719
MOD_GSK3_1 160 167 PF00069 0.777
MOD_GSK3_1 173 180 PF00069 0.631
MOD_GSK3_1 182 189 PF00069 0.653
MOD_GSK3_1 234 241 PF00069 0.785
MOD_GSK3_1 245 252 PF00069 0.568
MOD_GSK3_1 266 273 PF00069 0.785
MOD_GSK3_1 278 285 PF00069 0.794
MOD_GSK3_1 286 293 PF00069 0.606
MOD_GSK3_1 301 308 PF00069 0.575
MOD_GSK3_1 326 333 PF00069 0.681
MOD_GSK3_1 351 358 PF00069 0.734
MOD_GSK3_1 376 383 PF00069 0.820
MOD_GSK3_1 394 401 PF00069 0.568
MOD_GSK3_1 410 417 PF00069 0.536
MOD_GSK3_1 418 425 PF00069 0.686
MOD_GSK3_1 442 449 PF00069 0.778
MOD_GSK3_1 463 470 PF00069 0.654
MOD_GSK3_1 474 481 PF00069 0.690
MOD_GSK3_1 497 504 PF00069 0.600
MOD_GSK3_1 51 58 PF00069 0.809
MOD_GSK3_1 524 531 PF00069 0.803
MOD_GSK3_1 571 578 PF00069 0.825
MOD_GSK3_1 588 595 PF00069 0.533
MOD_GSK3_1 606 613 PF00069 0.608
MOD_GSK3_1 645 652 PF00069 0.666
MOD_GSK3_1 654 661 PF00069 0.667
MOD_GSK3_1 662 669 PF00069 0.561
MOD_GSK3_1 683 690 PF00069 0.767
MOD_GSK3_1 715 722 PF00069 0.820
MOD_LATS_1 108 114 PF00433 0.643
MOD_LATS_1 599 605 PF00433 0.833
MOD_N-GLC_1 238 243 PF02516 0.751
MOD_N-GLC_1 301 306 PF02516 0.801
MOD_N-GLC_1 410 415 PF02516 0.797
MOD_N-GLC_1 606 611 PF02516 0.736
MOD_N-GLC_1 666 671 PF02516 0.741
MOD_NEK2_1 150 155 PF00069 0.807
MOD_NEK2_1 166 171 PF00069 0.597
MOD_NEK2_1 181 186 PF00069 0.710
MOD_NEK2_1 301 306 PF00069 0.760
MOD_NEK2_1 464 469 PF00069 0.703
MOD_NEK2_1 649 654 PF00069 0.646
MOD_NEK2_1 681 686 PF00069 0.690
MOD_NEK2_1 687 692 PF00069 0.609
MOD_PIKK_1 137 143 PF00454 0.761
MOD_PIKK_1 25 31 PF00454 0.728
MOD_PIKK_1 452 458 PF00454 0.679
MOD_PIKK_1 611 617 PF00454 0.835
MOD_PIKK_1 633 639 PF00454 0.778
MOD_PIKK_1 662 668 PF00454 0.676
MOD_PIKK_1 712 718 PF00454 0.769
MOD_PKA_1 384 390 PF00069 0.708
MOD_PKA_1 658 664 PF00069 0.636
MOD_PKA_2 143 149 PF00069 0.663
MOD_PKA_2 174 180 PF00069 0.686
MOD_PKA_2 218 224 PF00069 0.861
MOD_PKA_2 25 31 PF00069 0.728
MOD_PKA_2 295 301 PF00069 0.728
MOD_PKA_2 384 390 PF00069 0.764
MOD_PKA_2 40 46 PF00069 0.596
MOD_PKA_2 592 598 PF00069 0.793
MOD_PKA_2 600 606 PF00069 0.713
MOD_PKA_2 623 629 PF00069 0.853
MOD_PKA_2 654 660 PF00069 0.657
MOD_PKB_1 101 109 PF00069 0.749
MOD_Plk_1 301 307 PF00069 0.801
MOD_Plk_1 410 416 PF00069 0.799
MOD_Plk_1 601 607 PF00069 0.762
MOD_Plk_2-3 484 490 PF00069 0.654
MOD_Plk_4 186 192 PF00069 0.677
MOD_Plk_4 210 216 PF00069 0.769
MOD_Plk_4 246 252 PF00069 0.679
MOD_Plk_4 398 404 PF00069 0.803
MOD_Plk_4 497 503 PF00069 0.603
MOD_ProDKin_1 129 135 PF00069 0.804
MOD_ProDKin_1 175 181 PF00069 0.841
MOD_ProDKin_1 184 190 PF00069 0.657
MOD_ProDKin_1 241 247 PF00069 0.745
MOD_ProDKin_1 266 272 PF00069 0.774
MOD_ProDKin_1 278 284 PF00069 0.630
MOD_ProDKin_1 286 292 PF00069 0.521
MOD_ProDKin_1 305 311 PF00069 0.579
MOD_ProDKin_1 337 343 PF00069 0.836
MOD_ProDKin_1 376 382 PF00069 0.726
MOD_ProDKin_1 418 424 PF00069 0.816
MOD_ProDKin_1 440 446 PF00069 0.690
MOD_ProDKin_1 467 473 PF00069 0.742
MOD_ProDKin_1 501 507 PF00069 0.644
MOD_ProDKin_1 58 64 PF00069 0.685
MOD_ProDKin_1 626 632 PF00069 0.654
MOD_ProDKin_1 710 716 PF00069 0.761
MOD_ProDKin_1 719 725 PF00069 0.712
TRG_ENDOCYTIC_2 2 5 PF00928 0.708
TRG_ENDOCYTIC_2 412 415 PF00928 0.798
TRG_ENDOCYTIC_2 72 75 PF00928 0.707
TRG_ER_diArg_1 100 103 PF00400 0.776
TRG_ER_diArg_1 18 21 PF00400 0.511
TRG_ER_diArg_1 295 297 PF00400 0.808
TRG_NES_CRM1_1 74 87 PF08389 0.622
TRG_NLS_Bipartite_1 296 314 PF00514 0.728
TRG_NLS_MonoExtN_4 309 314 PF00514 0.773

Homologs

Protein Taxonomy Sequence identity Coverage
A4HQ90 Leishmania braziliensis 52% 94%
A4IDY8 Leishmania infantum 99% 100%
E9AU08 Leishmania mexicana (strain MHOM/GT/2001/U1103) 72% 93%
Q4Q0I7 Leishmania major 85% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS