Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3S7XBS3_LEIDO

TriTrypDb:

LdCL_360061500 , LDHU3_36.7250

Length:

987

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7XBS3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XBS3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	485	489	PF00656	0.489
CLV_C14_Caspase3-7	604	608	PF00656	0.392
CLV_C14_Caspase3-7	899	903	PF00656	0.600
CLV_NRD_NRD_1	371	373	PF00675	0.534
CLV_NRD_NRD_1	482	484	PF00675	0.677
CLV_NRD_NRD_1	752	754	PF00675	0.603
CLV_NRD_NRD_1	955	957	PF00675	0.611
CLV_PCSK_KEX2_1	185	187	PF00082	0.569
CLV_PCSK_KEX2_1	206	208	PF00082	0.543
CLV_PCSK_KEX2_1	309	311	PF00082	0.595
CLV_PCSK_KEX2_1	371	373	PF00082	0.534
CLV_PCSK_KEX2_1	481	483	PF00082	0.645
CLV_PCSK_KEX2_1	510	512	PF00082	0.508
CLV_PCSK_KEX2_1	752	754	PF00082	0.603
CLV_PCSK_KEX2_1	87	89	PF00082	0.469
CLV_PCSK_KEX2_1	954	956	PF00082	0.623
CLV_PCSK_PC1ET2_1	185	187	PF00082	0.569
CLV_PCSK_PC1ET2_1	206	208	PF00082	0.543
CLV_PCSK_PC1ET2_1	309	311	PF00082	0.687
CLV_PCSK_PC1ET2_1	510	512	PF00082	0.508
CLV_PCSK_PC1ET2_1	87	89	PF00082	0.469
CLV_PCSK_PC7_1	748	754	PF00082	0.461
CLV_PCSK_PC7_1	83	89	PF00082	0.568
CLV_PCSK_SKI1_1	119	123	PF00082	0.468
CLV_PCSK_SKI1_1	83	87	PF00082	0.492
CLV_PCSK_SKI1_1	955	959	PF00082	0.524
CLV_Separin_Metazoa	745	749	PF03568	0.519
CLV_Separin_Metazoa	758	762	PF03568	0.495
DEG_APCC_DBOX_1	954	962	PF00400	0.441
DEG_SCF_FBW7_1	104	109	PF00400	0.698
DEG_SPOP_SBC_1	698	702	PF00917	0.582
DOC_CDC14_PxL_1	456	464	PF14671	0.470
DOC_CDC14_PxL_1	619	627	PF14671	0.587
DOC_CKS1_1	103	108	PF01111	0.701
DOC_CKS1_1	289	294	PF01111	0.460
DOC_CKS1_1	546	551	PF01111	0.683
DOC_CKS1_1	723	728	PF01111	0.479
DOC_CYCLIN_yCln2_LP_2	801	807	PF00134	0.481
DOC_MAPK_gen_1	34	42	PF00069	0.625
DOC_MAPK_gen_1	371	378	PF00069	0.516
DOC_MAPK_gen_1	765	773	PF00069	0.583
DOC_MAPK_gen_1	954	960	PF00069	0.526
DOC_MAPK_MEF2A_6	34	42	PF00069	0.560
DOC_MAPK_MEF2A_6	371	378	PF00069	0.516
DOC_MAPK_MEF2A_6	639	648	PF00069	0.703
DOC_MAPK_MEF2A_6	765	773	PF00069	0.570
DOC_PP1_RVXF_1	191	198	PF00149	0.572
DOC_PP1_RVXF_1	759	765	PF00149	0.574
DOC_PP2B_LxvP_1	221	224	PF13499	0.556
DOC_PP2B_LxvP_1	504	507	PF13499	0.468
DOC_SPAK_OSR1_1	411	415	PF12202	0.573
DOC_USP7_MATH_1	106	110	PF00917	0.708
DOC_USP7_MATH_1	17	21	PF00917	0.425
DOC_USP7_MATH_1	230	234	PF00917	0.741
DOC_USP7_MATH_1	29	33	PF00917	0.567
DOC_USP7_MATH_1	3	7	PF00917	0.559
DOC_USP7_MATH_1	334	338	PF00917	0.640
DOC_USP7_MATH_1	353	357	PF00917	0.707
DOC_USP7_MATH_1	533	537	PF00917	0.746
DOC_USP7_MATH_1	697	701	PF00917	0.602
DOC_USP7_MATH_1	873	877	PF00917	0.609
DOC_USP7_MATH_1	895	899	PF00917	0.436
DOC_USP7_MATH_1	913	917	PF00917	0.739
DOC_WW_Pin1_4	102	107	PF00397	0.686
DOC_WW_Pin1_4	288	293	PF00397	0.499
DOC_WW_Pin1_4	405	410	PF00397	0.568
DOC_WW_Pin1_4	440	445	PF00397	0.581
DOC_WW_Pin1_4	463	468	PF00397	0.614
DOC_WW_Pin1_4	51	56	PF00397	0.467
DOC_WW_Pin1_4	545	550	PF00397	0.682
DOC_WW_Pin1_4	574	579	PF00397	0.671
DOC_WW_Pin1_4	640	645	PF00397	0.703
DOC_WW_Pin1_4	722	727	PF00397	0.548
LIG_14-3-3_CanoR_1	142	148	PF00244	0.544
LIG_14-3-3_CanoR_1	16	26	PF00244	0.591
LIG_14-3-3_CanoR_1	170	178	PF00244	0.522
LIG_14-3-3_CanoR_1	186	192	PF00244	0.371
LIG_14-3-3_CanoR_1	28	34	PF00244	0.417
LIG_14-3-3_CanoR_1	336	341	PF00244	0.664
LIG_14-3-3_CanoR_1	360	365	PF00244	0.523
LIG_14-3-3_CanoR_1	436	446	PF00244	0.497
LIG_14-3-3_CanoR_1	475	481	PF00244	0.578
LIG_14-3-3_CanoR_1	511	521	PF00244	0.450
LIG_14-3-3_CanoR_1	537	546	PF00244	0.799
LIG_14-3-3_CanoR_1	686	693	PF00244	0.463
LIG_14-3-3_CanoR_1	69	74	PF00244	0.583
LIG_14-3-3_CanoR_1	831	838	PF00244	0.525
LIG_14-3-3_CanoR_1	847	851	PF00244	0.415
LIG_Actin_WH2_2	191	208	PF00022	0.529
LIG_Actin_WH2_2	20	36	PF00022	0.596
LIG_Actin_WH2_2	377	395	PF00022	0.527
LIG_Actin_WH2_2	559	577	PF00022	0.421
LIG_Actin_WH2_2	817	833	PF00022	0.392
LIG_Actin_WH2_2	890	908	PF00022	0.538
LIG_APCC_ABBA_1	960	965	PF00400	0.545
LIG_BIR_II_1	1	5	PF00653	0.507
LIG_BRCT_BRCA1_1	193	197	PF00533	0.487
LIG_BRCT_BRCA1_1	336	340	PF00533	0.685
LIG_BRCT_BRCA1_1	442	446	PF00533	0.482
LIG_BRCT_BRCA1_1	494	498	PF00533	0.506
LIG_BRCT_BRCA1_1	667	671	PF00533	0.581
LIG_BRCT_BRCA1_1	934	938	PF00533	0.436
LIG_CSL_BTD_1	801	804	PF09270	0.564
LIG_DLG_GKlike_1	336	343	PF00625	0.699
LIG_EH1_1	411	419	PF00400	0.466
LIG_EH1_1	659	667	PF00400	0.593
LIG_eIF4E_1	521	527	PF01652	0.480
LIG_EVH1_1	722	726	PF00568	0.502
LIG_EVH1_2	723	727	PF00568	0.614
LIG_FHA_1	105	111	PF00498	0.669
LIG_FHA_1	135	141	PF00498	0.478
LIG_FHA_1	170	176	PF00498	0.628
LIG_FHA_1	179	185	PF00498	0.532
LIG_FHA_1	284	290	PF00498	0.531
LIG_FHA_1	541	547	PF00498	0.807
LIG_FHA_1	616	622	PF00498	0.709
LIG_FHA_1	641	647	PF00498	0.695
LIG_FHA_1	686	692	PF00498	0.623
LIG_FHA_1	862	868	PF00498	0.514
LIG_FHA_1	870	876	PF00498	0.422
LIG_FHA_2	144	150	PF00498	0.524
LIG_FHA_2	602	608	PF00498	0.491
LIG_FHA_2	723	729	PF00498	0.664
LIG_FHA_2	847	853	PF00498	0.574
LIG_FHA_2	897	903	PF00498	0.462
LIG_FHA_2	906	912	PF00498	0.595
LIG_GBD_Chelix_1	212	220	PF00786	0.450
LIG_GBD_Chelix_1	566	574	PF00786	0.580
LIG_GBD_Chelix_1	842	850	PF00786	0.428
LIG_LIR_Gen_1	337	346	PF02991	0.687
LIG_LIR_Gen_1	849	858	PF02991	0.596
LIG_LIR_Gen_1	935	945	PF02991	0.460
LIG_LIR_Nem_3	247	252	PF02991	0.608
LIG_LIR_Nem_3	337	343	PF02991	0.673
LIG_LIR_Nem_3	443	448	PF02991	0.580
LIG_LIR_Nem_3	668	674	PF02991	0.363
LIG_LIR_Nem_3	849	854	PF02991	0.572
LIG_LIR_Nem_3	935	941	PF02991	0.441
LIG_NRBOX	143	149	PF00104	0.487
LIG_NRBOX	215	221	PF00104	0.445
LIG_NRBOX	593	599	PF00104	0.579
LIG_PCNA_PIPBox_1	629	638	PF02747	0.593
LIG_PCNA_yPIPBox_3	629	639	PF02747	0.598
LIG_Pex14_2	249	253	PF04695	0.592
LIG_Pex14_2	270	274	PF04695	0.453
LIG_SH2_CRK	523	527	PF00017	0.494
LIG_SH2_GRB2like	165	168	PF00017	0.535
LIG_SH2_GRB2like	742	745	PF00017	0.594
LIG_SH2_PTP2	161	164	PF00017	0.438
LIG_SH2_SRC	165	168	PF00017	0.535
LIG_SH2_SRC	521	524	PF00017	0.558
LIG_SH2_SRC	809	812	PF00017	0.434
LIG_SH2_STAP1	171	175	PF00017	0.560
LIG_SH2_STAP1	523	527	PF00017	0.516
LIG_SH2_STAT3	171	174	PF00017	0.533
LIG_SH2_STAT3	18	21	PF00017	0.490
LIG_SH2_STAT5	161	164	PF00017	0.438
LIG_SH2_STAT5	165	168	PF00017	0.443
LIG_SH2_STAT5	171	174	PF00017	0.533
LIG_SH2_STAT5	252	255	PF00017	0.610
LIG_SH2_STAT5	267	270	PF00017	0.307
LIG_SH2_STAT5	503	506	PF00017	0.576
LIG_SH2_STAT5	539	542	PF00017	0.774
LIG_SH2_STAT5	636	639	PF00017	0.631
LIG_SH2_STAT5	809	812	PF00017	0.434
LIG_SH3_3	219	225	PF00018	0.463
LIG_SH3_3	403	409	PF00018	0.697
LIG_SH3_3	543	549	PF00018	0.672
LIG_SH3_3	720	726	PF00018	0.515
LIG_SH3_3	875	881	PF00018	0.594
LIG_SH3_3	98	104	PF00018	0.611
LIG_SUMO_SIM_anti_2	22	28	PF11976	0.483
LIG_SUMO_SIM_anti_2	286	291	PF11976	0.439
LIG_SUMO_SIM_anti_2	728	734	PF11976	0.474
LIG_SUMO_SIM_anti_2	852	859	PF11976	0.484
LIG_SUMO_SIM_anti_2	972	978	PF11976	0.510
LIG_SUMO_SIM_par_1	285	291	PF11976	0.437
LIG_TYR_ITIM	159	164	PF00017	0.532
LIG_UBA3_1	289	298	PF00899	0.638
LIG_UBA3_1	593	602	PF00899	0.584
LIG_Vh1_VBS_1	886	904	PF01044	0.576
LIG_WRC_WIRS_1	271	276	PF05994	0.455
MOD_CDC14_SPxK_1	408	411	PF00782	0.608
MOD_CDK_SPxK_1	405	411	PF00069	0.650
MOD_CDK_SPxK_1	545	551	PF00069	0.683
MOD_CDK_SPxxK_3	288	295	PF00069	0.468
MOD_CK1_1	169	175	PF00069	0.615
MOD_CK1_1	187	193	PF00069	0.330
MOD_CK1_1	226	232	PF00069	0.596
MOD_CK1_1	233	239	PF00069	0.653
MOD_CK1_1	273	279	PF00069	0.542
MOD_CK1_1	356	362	PF00069	0.611
MOD_CK1_1	440	446	PF00069	0.550
MOD_CK1_1	463	469	PF00069	0.492
MOD_CK1_1	476	482	PF00069	0.508
MOD_CK1_1	50	56	PF00069	0.493
MOD_CK1_1	538	544	PF00069	0.741
MOD_CK1_1	615	621	PF00069	0.635
MOD_CK1_1	669	675	PF00069	0.659
MOD_CK1_1	869	875	PF00069	0.591
MOD_CK1_1	94	100	PF00069	0.572
MOD_CK2_1	143	149	PF00069	0.516
MOD_CK2_1	33	39	PF00069	0.651
MOD_CK2_1	51	57	PF00069	0.344
MOD_CK2_1	512	518	PF00069	0.469
MOD_CK2_1	846	852	PF00069	0.570
MOD_CK2_1	943	949	PF00069	0.596
MOD_CK2_1	964	970	PF00069	0.589
MOD_Cter_Amidation	750	753	PF01082	0.644
MOD_GlcNHglycan	1	4	PF01048	0.563
MOD_GlcNHglycan	208	211	PF01048	0.501
MOD_GlcNHglycan	228	231	PF01048	0.389
MOD_GlcNHglycan	236	239	PF01048	0.642
MOD_GlcNHglycan	254	257	PF01048	0.375
MOD_GlcNHglycan	262	265	PF01048	0.450
MOD_GlcNHglycan	320	323	PF01048	0.539
MOD_GlcNHglycan	336	339	PF01048	0.418
MOD_GlcNHglycan	430	433	PF01048	0.613
MOD_GlcNHglycan	448	451	PF01048	0.445
MOD_GlcNHglycan	452	455	PF01048	0.459
MOD_GlcNHglycan	493	497	PF01048	0.427
MOD_GlcNHglycan	553	556	PF01048	0.623
MOD_GlcNHglycan	560	563	PF01048	0.548
MOD_GlcNHglycan	607	610	PF01048	0.624
MOD_GlcNHglycan	675	678	PF01048	0.601
MOD_GlcNHglycan	74	77	PF01048	0.507
MOD_GlcNHglycan	786	790	PF01048	0.565
MOD_GlcNHglycan	832	835	PF01048	0.529
MOD_GlcNHglycan	902	905	PF01048	0.571
MOD_GlcNHglycan	946	949	PF01048	0.632
MOD_GlcNHglycan	96	99	PF01048	0.532
MOD_GlcNHglycan	965	969	PF01048	0.419
MOD_GSK3_1	102	109	PF00069	0.700
MOD_GSK3_1	165	172	PF00069	0.569
MOD_GSK3_1	187	194	PF00069	0.488
MOD_GSK3_1	226	233	PF00069	0.619
MOD_GSK3_1	248	255	PF00069	0.439
MOD_GSK3_1	29	36	PF00069	0.610
MOD_GSK3_1	314	321	PF00069	0.562
MOD_GSK3_1	325	332	PF00069	0.445
MOD_GSK3_1	356	363	PF00069	0.600
MOD_GSK3_1	446	453	PF00069	0.604
MOD_GSK3_1	47	54	PF00069	0.439
MOD_GSK3_1	512	519	PF00069	0.466
MOD_GSK3_1	533	540	PF00069	0.769
MOD_GSK3_1	601	608	PF00069	0.500
MOD_GSK3_1	665	672	PF00069	0.601
MOD_GSK3_1	685	692	PF00069	0.342
MOD_GSK3_1	718	725	PF00069	0.701
MOD_GSK3_1	825	832	PF00069	0.605
MOD_GSK3_1	869	876	PF00069	0.497
MOD_GSK3_1	896	903	PF00069	0.578
MOD_N-GLC_1	166	171	PF02516	0.437
MOD_N-GLC_1	794	799	PF02516	0.680
MOD_N-GLC_1	869	874	PF02516	0.594
MOD_NEK2_1	127	132	PF00069	0.498
MOD_NEK2_1	143	148	PF00069	0.352
MOD_NEK2_1	184	189	PF00069	0.532
MOD_NEK2_1	191	196	PF00069	0.447
MOD_NEK2_1	270	275	PF00069	0.450
MOD_NEK2_1	283	288	PF00069	0.472
MOD_NEK2_1	302	307	PF00069	0.719
MOD_NEK2_1	33	38	PF00069	0.629
MOD_NEK2_1	376	381	PF00069	0.429
MOD_NEK2_1	392	397	PF00069	0.594
MOD_NEK2_1	402	407	PF00069	0.639
MOD_NEK2_1	417	422	PF00069	0.388
MOD_NEK2_1	438	443	PF00069	0.663
MOD_NEK2_1	446	451	PF00069	0.505
MOD_NEK2_1	462	467	PF00069	0.408
MOD_NEK2_1	473	478	PF00069	0.452
MOD_NEK2_1	492	497	PF00069	0.486
MOD_NEK2_1	593	598	PF00069	0.447
MOD_NEK2_1	628	633	PF00069	0.571
MOD_NEK2_1	665	670	PF00069	0.441
MOD_NEK2_1	731	736	PF00069	0.555
MOD_NEK2_1	785	790	PF00069	0.701
MOD_NEK2_1	830	835	PF00069	0.565
MOD_NEK2_1	846	851	PF00069	0.459
MOD_NEK2_1	866	871	PF00069	0.246
MOD_NEK2_1	900	905	PF00069	0.610
MOD_NEK2_1	92	97	PF00069	0.483
MOD_NEK2_1	932	937	PF00069	0.557
MOD_NEK2_1	964	969	PF00069	0.648
MOD_NEK2_2	29	34	PF00069	0.416
MOD_OFUCOSY	808	815	PF10250	0.596
MOD_OFUCOSY	90	96	PF10250	0.435
MOD_PIKK_1	17	23	PF00454	0.587
MOD_PIKK_1	170	176	PF00454	0.628
MOD_PIKK_1	224	230	PF00454	0.656
MOD_PIKK_1	302	308	PF00454	0.723
MOD_PIKK_1	353	359	PF00454	0.667
MOD_PIKK_1	666	672	PF00454	0.451
MOD_PIKK_1	777	783	PF00454	0.527
MOD_PIKK_1	794	800	PF00454	0.559
MOD_PIKK_1	825	831	PF00454	0.556
MOD_PIKK_1	873	879	PF00454	0.510
MOD_PIKK_1	932	938	PF00454	0.448
MOD_PK_1	360	366	PF00069	0.489
MOD_PKA_1	206	212	PF00069	0.541
MOD_PKA_1	481	487	PF00069	0.490
MOD_PKA_2	169	175	PF00069	0.430
MOD_PKA_2	206	212	PF00069	0.499
MOD_PKA_2	33	39	PF00069	0.638
MOD_PKA_2	392	398	PF00069	0.632
MOD_PKA_2	438	444	PF00069	0.623
MOD_PKA_2	481	487	PF00069	0.516
MOD_PKA_2	685	691	PF00069	0.515
MOD_PKA_2	830	836	PF00069	0.542
MOD_PKA_2	846	852	PF00069	0.517
MOD_Plk_1	166	172	PF00069	0.447
MOD_Plk_4	143	149	PF00069	0.578
MOD_Plk_4	248	254	PF00069	0.537
MOD_Plk_4	3	9	PF00069	0.524
MOD_Plk_4	402	408	PF00069	0.670
MOD_Plk_4	465	471	PF00069	0.588
MOD_Plk_4	516	522	PF00069	0.453
MOD_Plk_4	593	599	PF00069	0.452
MOD_Plk_4	699	705	PF00069	0.412
MOD_Plk_4	846	852	PF00069	0.489
MOD_Plk_4	896	902	PF00069	0.482
MOD_ProDKin_1	102	108	PF00069	0.686
MOD_ProDKin_1	288	294	PF00069	0.500
MOD_ProDKin_1	405	411	PF00069	0.558
MOD_ProDKin_1	440	446	PF00069	0.579
MOD_ProDKin_1	463	469	PF00069	0.606
MOD_ProDKin_1	51	57	PF00069	0.472
MOD_ProDKin_1	545	551	PF00069	0.683
MOD_ProDKin_1	574	580	PF00069	0.680
MOD_ProDKin_1	640	646	PF00069	0.707
MOD_ProDKin_1	722	728	PF00069	0.541
MOD_SUMO_for_1	296	299	PF00179	0.670
TRG_DiLeu_BaLyEn_6	139	144	PF01217	0.482
TRG_DiLeu_BaLyEn_6	236	241	PF01217	0.514
TRG_DiLeu_BaLyEn_6	38	43	PF01217	0.597
TRG_DiLeu_BaLyEn_6	522	527	PF01217	0.447
TRG_DiLeu_BaLyEn_6	862	867	PF01217	0.471
TRG_DiLeu_LyEn_5	620	625	PF01217	0.656
TRG_ENDOCYTIC_2	161	164	PF00928	0.438
TRG_ENDOCYTIC_2	267	270	PF00928	0.453
TRG_ENDOCYTIC_2	503	506	PF00928	0.472
TRG_ENDOCYTIC_2	523	526	PF00928	0.340
TRG_ER_diArg_1	370	372	PF00400	0.539
TRG_ER_diArg_1	480	483	PF00400	0.567
TRG_ER_diArg_1	764	767	PF00400	0.487
TRG_ER_diArg_1	953	956	PF00400	0.615
TRG_NES_CRM1_1	837	852	PF08389	0.416
TRG_NLS_MonoExtN_4	507	513	PF00514	0.607
TRG_Pf-PMV_PEXEL_1	41	45	PF00026	0.584
TRG_Pf-PMV_PEXEL_1	511	516	PF00026	0.549
TRG_Pf-PMV_PEXEL_1	767	772	PF00026	0.397

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P493	Leptomonas seymouri	36%	98%
E9AHY3	Leishmania infantum	100%	100%
E9ATV4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%
Q4Q0P2	Leishmania major	88%	100%