Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7XBQ9_LEIDO

TriTrypDb:

LdBPK_365020.1 , LdCL_360057400 , LDHU3_36.6740

Length:

926

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A0A3S7XBQ9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XBQ9

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	565	569	PF00656	0.657
CLV_C14_Caspase3-7	89	93	PF00656	0.585
CLV_NRD_NRD_1	141	143	PF00675	0.528
CLV_NRD_NRD_1	149	151	PF00675	0.493
CLV_NRD_NRD_1	199	201	PF00675	0.457
CLV_NRD_NRD_1	234	236	PF00675	0.570
CLV_NRD_NRD_1	320	322	PF00675	0.551
CLV_NRD_NRD_1	394	396	PF00675	0.561
CLV_NRD_NRD_1	452	454	PF00675	0.562
CLV_NRD_NRD_1	531	533	PF00675	0.665

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I6T1	Leptomonas seymouri	43%	97%
A4HPZ6	Leishmania braziliensis	69%	99%
A4IDQ7	Leishmania infantum	100%	100%
D0A4F0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	100%
E9ATR3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%
Q4Q0T4	Leishmania major	88%	100%
V5BQ47	Trypanosoma cruzi	27%	100%

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