Calponin homology (CH) domain containing protein, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7XBQ1_LEIDO

TriTrypDb:

LdBPK_365150.1 , LdCL_360058700 , LDHU3_36.6890

Length:

696

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005929	cilium	4	1
GO:0005938	cell cortex	3	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0042995	cell projection	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043233	organelle lumen	3	1

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Expansion

Sequence features

A0A3S7XBQ1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XBQ1

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	276	280	PF00656	0.509
CLV_C14_Caspase3-7	287	291	PF00656	0.370
CLV_C14_Caspase3-7	313	317	PF00656	0.444
CLV_C14_Caspase3-7	536	540	PF00656	0.775
CLV_C14_Caspase3-7	551	555	PF00656	0.572
CLV_C14_Caspase3-7	93	97	PF00656	0.664
CLV_NRD_NRD_1	102	104	PF00675	0.669
CLV_NRD_NRD_1	112	114	PF00675	0.635
CLV_NRD_NRD_1	273	275	PF00675	0.433
CLV_NRD_NRD_1	546	548	PF00675	0.799

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A4HQ09	Leishmania braziliensis	65%	100%
A4IDS0	Leishmania infantum	99%	100%
E9ATS6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%
Q4Q0S0	Leishmania major	87%	100%

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