PABS domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7XBN4_LEIDO

TriTrypDb:

LdBPK_365030.1 , LdCL_360057500 , LDHU3_36.6750

Length:

511

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7XBN4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XBN4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	137	141	PF00656	0.692
CLV_NRD_NRD_1	10	12	PF00675	0.704
CLV_NRD_NRD_1	101	103	PF00675	0.751
CLV_NRD_NRD_1	211	213	PF00675	0.513
CLV_NRD_NRD_1	23	25	PF00675	0.632
CLV_PCSK_FUR_1	7	11	PF00082	0.686
CLV_PCSK_KEX2_1	10	12	PF00082	0.643
CLV_PCSK_KEX2_1	162	164	PF00082	0.616
CLV_PCSK_KEX2_1	21	23	PF00082	0.582
CLV_PCSK_KEX2_1	31	33	PF00082	0.528
CLV_PCSK_KEX2_1	7	9	PF00082	0.652
CLV_PCSK_KEX2_1	78	80	PF00082	0.496
CLV_PCSK_PC1ET2_1	162	164	PF00082	0.616
CLV_PCSK_PC1ET2_1	21	23	PF00082	0.656
CLV_PCSK_PC1ET2_1	31	33	PF00082	0.528
CLV_PCSK_PC1ET2_1	78	80	PF00082	0.496
CLV_PCSK_PC7_1	18	24	PF00082	0.534
CLV_PCSK_SKI1_1	323	327	PF00082	0.466
CLV_PCSK_SKI1_1	403	407	PF00082	0.564
CLV_PCSK_SKI1_1	75	79	PF00082	0.499
DEG_COP1_1	54	61	PF00400	0.410
DEG_ODPH_VHL_1	4	17	PF01847	0.718
DEG_SPOP_SBC_1	268	272	PF00917	0.751
DOC_MAPK_gen_1	7	17	PF00069	0.631
DOC_MAPK_JIP1_4	407	413	PF00069	0.556
DOC_MAPK_MEF2A_6	46	53	PF00069	0.582
DOC_MAPK_NFAT4_5	46	54	PF00069	0.590
DOC_USP7_MATH_1	109	113	PF00917	0.741
DOC_USP7_MATH_1	238	242	PF00917	0.679
DOC_WW_Pin1_4	131	136	PF00397	0.721
DOC_WW_Pin1_4	212	217	PF00397	0.409
LIG_14-3-3_CanoR_1	110	114	PF00244	0.735
LIG_14-3-3_CanoR_1	129	136	PF00244	0.489
LIG_14-3-3_CanoR_1	245	254	PF00244	0.647
LIG_14-3-3_CanoR_1	276	280	PF00244	0.697
LIG_14-3-3_CanoR_1	443	451	PF00244	0.536
LIG_14-3-3_CanoR_1	52	59	PF00244	0.422
LIG_14-3-3_CanoR_1	64	72	PF00244	0.429
LIG_14-3-3_CanoR_1	8	17	PF00244	0.692
LIG_14-3-3_CanoR_1	86	90	PF00244	0.510
LIG_14-3-3_CterR_2	507	511	PF00244	0.474
LIG_Actin_WH2_2	190	206	PF00022	0.440
LIG_Actin_WH2_2	76	94	PF00022	0.476
LIG_FHA_1	10	16	PF00498	0.669
LIG_FHA_1	303	309	PF00498	0.573
LIG_FHA_1	400	406	PF00498	0.487
LIG_FHA_1	53	59	PF00498	0.536
LIG_FHA_1	64	70	PF00498	0.482
LIG_FHA_1	86	92	PF00498	0.544
LIG_FHA_2	137	143	PF00498	0.774
LIG_FHA_2	226	232	PF00498	0.615
LIG_FHA_2	348	354	PF00498	0.523
LIG_FHA_2	373	379	PF00498	0.441
LIG_FHA_2	468	474	PF00498	0.487
LIG_FHA_2	96	102	PF00498	0.727
LIG_GBD_Chelix_1	474	482	PF00786	0.467
LIG_LIR_Apic_2	112	116	PF02991	0.754
LIG_LIR_Gen_1	194	203	PF02991	0.431
LIG_LIR_Gen_1	375	385	PF02991	0.517
LIG_LIR_Nem_3	194	198	PF02991	0.432
LIG_LIR_Nem_3	375	380	PF02991	0.515
LIG_LIR_Nem_3	473	479	PF02991	0.509
LIG_MYND_1	2	6	PF01753	0.736
LIG_Pex14_2	44	48	PF04695	0.562
LIG_SH2_CRK	200	204	PF00017	0.537
LIG_SH2_CRK	377	381	PF00017	0.425
LIG_SH2_CRK	428	432	PF00017	0.569
LIG_SH2_NCK_1	428	432	PF00017	0.569
LIG_SH2_SRC	230	233	PF00017	0.435
LIG_SH2_STAP1	377	381	PF00017	0.425
LIG_SH2_STAP1	428	432	PF00017	0.569
LIG_SH2_STAP1	463	467	PF00017	0.478
LIG_SH2_STAP1	479	483	PF00017	0.444
LIG_SH2_STAT5	148	151	PF00017	0.464
LIG_SH2_STAT5	200	203	PF00017	0.533
LIG_SH3_1	103	109	PF00018	0.703
LIG_SH3_2	3	8	PF14604	0.734
LIG_SH3_3	103	109	PF00018	0.575
LIG_SH3_3	91	97	PF00018	0.548
LIG_SUMO_SIM_par_1	329	336	PF11976	0.451
LIG_TRAF2_1	98	101	PF00917	0.751
LIG_TYR_ITIM	198	203	PF00017	0.532
LIG_TYR_ITSM	373	380	PF00017	0.437
LIG_WRC_WIRS_1	192	197	PF05994	0.433
LIG_WW_3	107	111	PF00397	0.810
MOD_CK1_1	167	173	PF00069	0.565
MOD_CK1_1	191	197	PF00069	0.540
MOD_CK1_1	233	239	PF00069	0.731
MOD_CK2_1	284	290	PF00069	0.523
MOD_CK2_1	95	101	PF00069	0.716
MOD_GlcNHglycan	136	139	PF01048	0.729
MOD_GlcNHglycan	25	28	PF01048	0.429
MOD_GlcNHglycan	250	253	PF01048	0.720
MOD_GlcNHglycan	420	423	PF01048	0.469
MOD_GSK3_1	232	239	PF00069	0.621
MOD_GSK3_1	347	354	PF00069	0.578
MOD_GSK3_1	457	464	PF00069	0.455
MOD_N-GLC_1	246	251	PF02516	0.706
MOD_N-GLC_1	465	470	PF02516	0.458
MOD_NEK2_1	17	22	PF00069	0.655
MOD_NEK2_1	38	43	PF00069	0.470
MOD_NEK2_1	388	393	PF00069	0.569
MOD_NEK2_1	465	470	PF00069	0.433
MOD_NEK2_1	51	56	PF00069	0.510
MOD_PIKK_1	240	246	PF00454	0.596
MOD_PIKK_1	269	275	PF00454	0.726
MOD_PIKK_1	63	69	PF00454	0.603
MOD_PKA_1	23	29	PF00069	0.600
MOD_PKA_1	9	15	PF00069	0.684
MOD_PKA_2	109	115	PF00069	0.810
MOD_PKA_2	128	134	PF00069	0.493
MOD_PKA_2	164	170	PF00069	0.604
MOD_PKA_2	17	23	PF00069	0.656
MOD_PKA_2	275	281	PF00069	0.705
MOD_PKA_2	51	57	PF00069	0.515
MOD_PKA_2	63	69	PF00069	0.501
MOD_PKA_2	85	91	PF00069	0.532
MOD_PKA_2	9	15	PF00069	0.679
MOD_PKB_1	7	15	PF00069	0.701
MOD_Plk_1	167	173	PF00069	0.565
MOD_Plk_1	38	44	PF00069	0.474
MOD_Plk_4	172	178	PF00069	0.490
MOD_Plk_4	188	194	PF00069	0.454
MOD_Plk_4	445	451	PF00069	0.424
MOD_Plk_4	478	484	PF00069	0.553
MOD_Plk_4	488	494	PF00069	0.414
MOD_ProDKin_1	131	137	PF00069	0.720
MOD_ProDKin_1	212	218	PF00069	0.409
MOD_SUMO_rev_2	13	17	PF00179	0.772
MOD_SUMO_rev_2	278	288	PF00179	0.644
MOD_SUMO_rev_2	353	358	PF00179	0.629
TRG_ENDOCYTIC_2	200	203	PF00928	0.533
TRG_ENDOCYTIC_2	377	380	PF00928	0.426
TRG_ENDOCYTIC_2	381	384	PF00928	0.441
TRG_ENDOCYTIC_2	428	431	PF00928	0.474
TRG_ENDOCYTIC_2	479	482	PF00928	0.445
TRG_ER_diArg_1	22	24	PF00400	0.638
TRG_ER_diArg_1	504	507	PF00400	0.462
TRG_ER_diArg_1	6	9	PF00400	0.698
TRG_NLS_Bipartite_1	7	25	PF00514	0.664
TRG_NLS_MonoCore_2	20	25	PF00514	0.714
TRG_NLS_MonoExtN_4	18	25	PF00514	0.562

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDJ0	Leptomonas seymouri	55%	100%
A4HPZ7	Leishmania braziliensis	77%	100%
A4IDQ8	Leishmania infantum	100%	100%
E9ATR4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q0T3	Leishmania major	92%	100%