Cytochrome_b5_1_putative/GeneDB:LmjF.36.4675

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

cytochrome b5 1, putative

Species:

Leishmania donovani

UniProt:

A0A3S7XBN0_LEIDO

TriTrypDb:

LdBPK_364910.1 , LdCL_360056200 , LDHU3_36.6590

Length:

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3S7XBN0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XBN0

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	1
GO:0020037	heme binding	4	1
GO:0046906	tetrapyrrole binding	3	1
GO:0097159	organic cyclic compound binding	2	1
GO:1901363	heterocyclic compound binding	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	66	70	PF00082	0.430
DEG_Nend_UBRbox_1	1	4	PF02207	0.614
LIG_BRCT_BRCA1_1	52	56	PF00533	0.430
LIG_Clathr_ClatBox_1	42	46	PF01394	0.424
LIG_FHA_2	12	18	PF00498	0.395
LIG_FHA_2	3	9	PF00498	0.376
LIG_LIR_Gen_1	17	27	PF02991	0.429
LIG_LIR_Nem_3	15	21	PF02991	0.395
LIG_SH2_STAT5	4	7	PF00017	0.376
LIG_SH2_STAT5	72	75	PF00017	0.501
LIG_SUMO_SIM_par_1	41	47	PF11976	0.410
LIG_TRAF2_1	5	8	PF00917	0.376
LIG_UBA3_1	42	50	PF00899	0.472
MOD_CK2_1	2	8	PF00069	0.376
MOD_GlcNHglycan	46	49	PF01048	0.460
MOD_NEK2_1	11	16	PF00069	0.491
MOD_NEK2_1	33	38	PF00069	0.346
MOD_PIKK_1	12	18	PF00454	0.465
MOD_PK_1	50	56	PF00069	0.501
MOD_Plk_4	50	56	PF00069	0.413
TRG_ENDOCYTIC_2	18	21	PF00928	0.385
TRG_ER_diArg_1	64	67	PF00400	0.326
TRG_Pf-PMV_PEXEL_1	66	70	PF00026	0.326

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFL2	Leptomonas seymouri	64%	99%
A0A0S4JHB7	Bodo saltans	43%	93%
A4HPY5	Leishmania braziliensis	80%	100%
A4IDP6	Leishmania infantum	100%	100%
E9ATQ2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
Q4Q0U6	Leishmania major	92%	100%