Amastin surface glycoprotein, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Amastin surface glycoprotein, putative

Species:

Leishmania donovani

UniProt:

A0A3S7XBG4_LEIDO

TriTrypDb:

LdBPK_364330.1 , LdCL_360050400 , LDHU3_36.5850

Length:

237

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6

Expansion

Sequence features

A0A3S7XBG4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XBG4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	11	13	PF00082	0.437
CLV_PCSK_PC1ET2_1	11	13	PF00082	0.452
CLV_PCSK_PC7_1	7	13	PF00082	0.452
CLV_PCSK_SKI1_1	133	137	PF00082	0.464
CLV_PCSK_SKI1_1	164	168	PF00082	0.264
CLV_PCSK_SKI1_1	29	33	PF00082	0.344
DEG_APCC_DBOX_1	163	171	PF00400	0.452
DEG_APCC_DBOX_1	28	36	PF00400	0.344
DOC_CKS1_1	210	215	PF01111	0.320
DOC_CKS1_1	52	57	PF01111	0.438
DOC_MAPK_DCC_7	164	172	PF00069	0.493
DOC_MAPK_MEF2A_6	102	109	PF00069	0.395
DOC_MAPK_MEF2A_6	164	172	PF00069	0.452
DOC_MAPK_MEF2A_6	93	100	PF00069	0.494
DOC_PP2B_PxIxI_1	54	60	PF00149	0.429
DOC_PP4_FxxP_1	52	55	PF00568	0.400
DOC_USP7_MATH_1	21	25	PF00917	0.334
DOC_WW_Pin1_4	209	214	PF00397	0.320
DOC_WW_Pin1_4	51	56	PF00397	0.429
LIG_Actin_WH2_2	15	31	PF00022	0.493
LIG_BRCT_BRCA1_1	158	162	PF00533	0.336
LIG_EH1_1	226	234	PF00400	0.344
LIG_FHA_1	147	153	PF00498	0.431
LIG_FHA_1	224	230	PF00498	0.344
LIG_FHA_1	52	58	PF00498	0.489
LIG_FHA_1	89	95	PF00498	0.372
LIG_LIR_Apic_2	50	55	PF02991	0.385
LIG_LIR_Gen_1	159	170	PF02991	0.375
LIG_LIR_Nem_3	108	114	PF02991	0.486
LIG_LIR_Nem_3	131	135	PF02991	0.290
LIG_LIR_Nem_3	146	151	PF02991	0.335
LIG_LIR_Nem_3	163	169	PF02991	0.508
LIG_LIR_Nem_3	33	39	PF02991	0.361
LIG_LIR_Nem_3	76	81	PF02991	0.394
LIG_MLH1_MIPbox_1	158	162	PF16413	0.344
LIG_NRBOX	38	44	PF00104	0.348
LIG_PDZ_Class_2	232	237	PF00595	0.500
LIG_Pex14_2	132	136	PF04695	0.282
LIG_Pex14_2	162	166	PF04695	0.322
LIG_Pex14_2	217	221	PF04695	0.348
LIG_REV1ctd_RIR_1	133	141	PF16727	0.296
LIG_REV1ctd_RIR_1	159	167	PF16727	0.344
LIG_SH2_CRK	111	115	PF00017	0.449
LIG_SH2_STAT3	113	116	PF00017	0.462
LIG_SH2_STAT3	122	125	PF00017	0.279
LIG_SH2_STAT5	113	116	PF00017	0.479
LIG_SH2_STAT5	227	230	PF00017	0.344
LIG_SH2_STAT5	36	39	PF00017	0.344
LIG_SH3_3	104	110	PF00018	0.412
LIG_SUMO_SIM_par_1	143	149	PF11976	0.344
LIG_TYR_ITIM	109	114	PF00017	0.556
LIG_TYR_ITIM	34	39	PF00017	0.348
LIG_Vh1_VBS_1	178	196	PF01044	0.250
MOD_CDK_SPxxK_3	51	58	PF00069	0.545
MOD_CK1_1	143	149	PF00069	0.348
MOD_CK1_1	223	229	PF00069	0.453
MOD_CK1_1	231	237	PF00069	0.410
MOD_CK1_1	24	30	PF00069	0.250
MOD_CK1_1	50	56	PF00069	0.543
MOD_GSK3_1	156	163	PF00069	0.369
MOD_GSK3_1	174	181	PF00069	0.166
MOD_GSK3_1	205	212	PF00069	0.481
MOD_GSK3_1	223	230	PF00069	0.235
MOD_GSK3_1	47	54	PF00069	0.472
MOD_N-GLC_1	116	121	PF02516	0.348
MOD_N-GLC_1	88	93	PF02516	0.418
MOD_NEK2_1	156	161	PF00069	0.304
MOD_NEK2_1	174	179	PF00069	0.166
MOD_NEK2_1	180	185	PF00069	0.314
MOD_NEK2_1	228	233	PF00069	0.344
MOD_NEK2_1	98	103	PF00069	0.533
MOD_NEK2_2	21	26	PF00069	0.337
MOD_PIKK_1	116	122	PF00454	0.348
MOD_Plk_1	116	122	PF00069	0.428
MOD_Plk_1	47	53	PF00069	0.523
MOD_Plk_1	62	68	PF00069	0.407
MOD_Plk_1	81	87	PF00069	0.322
MOD_Plk_4	143	149	PF00069	0.344
MOD_Plk_4	21	27	PF00069	0.303
MOD_Plk_4	223	229	PF00069	0.354
MOD_Plk_4	231	237	PF00069	0.605
MOD_Plk_4	30	36	PF00069	0.361
MOD_Plk_4	69	75	PF00069	0.533
MOD_Plk_4	81	87	PF00069	0.458
MOD_ProDKin_1	209	215	PF00069	0.320
MOD_ProDKin_1	51	57	PF00069	0.529
MOD_SUMO_rev_2	5	13	PF00179	0.557
TRG_DiLeu_BaLyEn_6	165	170	PF01217	0.344
TRG_ENDOCYTIC_2	111	114	PF00928	0.612
TRG_ENDOCYTIC_2	198	201	PF00928	0.374
TRG_ENDOCYTIC_2	36	39	PF00928	0.359
TRG_Pf-PMV_PEXEL_1	190	194	PF00026	0.362

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PA59	Leptomonas seymouri	62%	100%
A0A1X0P3I9	Trypanosomatidae	33%	100%
A4IE61	Leishmania infantum	99%	100%
E9ATJ6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
Q4Q102	Leishmania major	93%	100%