LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7XBF2_LEIDO
TriTrypDb:
LdBPK_364110.1 , LdCL_360048100 , LDHU3_36.5520
Length:
133

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0016020 membrane 2 10
GO:0110165 cellular anatomical entity 1 10

Expansion

Sequence features

A0A3S7XBF2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XBF2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_SKI1_1 34 38 PF00082 0.369
CLV_PCSK_SKI1_1 76 80 PF00082 0.442
DEG_APCC_DBOX_1 33 41 PF00400 0.496
DEG_APCC_DBOX_1 75 83 PF00400 0.255
DOC_USP7_MATH_1 124 128 PF00917 0.623
LIG_BRCT_BRCA1_1 46 50 PF00533 0.409
LIG_EVH1_2 70 74 PF00568 0.471
LIG_FHA_1 51 57 PF00498 0.355
LIG_FHA_1 86 92 PF00498 0.395
LIG_LIR_Nem_3 60 64 PF02991 0.433
LIG_NRBOX 36 42 PF00104 0.355
LIG_Pex14_2 74 78 PF04695 0.476
LIG_SH3_3 65 71 PF00018 0.427
LIG_SUMO_SIM_anti_2 45 51 PF11976 0.355
LIG_SUMO_SIM_anti_2 94 100 PF11976 0.319
LIG_SUMO_SIM_par_1 55 60 PF11976 0.391
LIG_SUMO_SIM_par_1 94 100 PF11976 0.421
LIG_TRFH_1 64 68 PF08558 0.402
LIG_UBA3_1 98 105 PF00899 0.402
LIG_WRC_WIRS_1 58 63 PF05994 0.540
LIG_WRC_WIRS_1 75 80 PF05994 0.485
MOD_CK1_1 127 133 PF00069 0.644
MOD_GlcNHglycan 50 53 PF01048 0.373
MOD_GlcNHglycan 7 10 PF01048 0.350
MOD_GSK3_1 44 51 PF00069 0.298
MOD_GSK3_1 97 104 PF00069 0.355
MOD_NEK2_1 101 106 PF00069 0.559
MOD_NEK2_1 116 121 PF00069 0.501
MOD_NEK2_1 42 47 PF00069 0.381
MOD_NEK2_1 50 55 PF00069 0.436
MOD_NEK2_1 57 62 PF00069 0.516
MOD_NEK2_1 74 79 PF00069 0.462
MOD_Plk_4 23 29 PF00069 0.374
MOD_Plk_4 44 50 PF00069 0.322
MOD_Plk_4 91 97 PF00069 0.392
TRG_DiLeu_BaEn_1 112 117 PF01217 0.656

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IKW4 Leptomonas seymouri 72% 100%
A0A0S4JIM1 Bodo saltans 38% 100%
A0A1X0P3L7 Trypanosomatidae 40% 100%
A0A422NKK4 Trypanosoma rangeli 39% 100%
A4HPR0 Leishmania braziliensis 86% 100%
A4ID04 Leishmania infantum 100% 100%
D0A8F5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 93%
E9ATH4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 100%
Q4Q123 Leishmania major 95% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS