Nascent polypeptide-associated complex subunit beta

Quick info Annotations Localization Abundance Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

transcription factor BTF3, putative

Species:

Leishmania donovani

UniProt:

A0A3S7XBD2_LEIDO

TriTrypDb:

LdBPK_363960.1 , LdCL_360046600 , LDHU3_36.5300

Length:

103

Annotations

Annotations by Jardim et al.

Transcription, Nascent polypeptide-associated complex subunit beta

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 16

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A0A3S7XBD2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XBD2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	96	100	PF00656	0.488
CLV_NRD_NRD_1	10	12	PF00675	0.463
CLV_NRD_NRD_1	24	26	PF00675	0.488
CLV_NRD_NRD_1	45	47	PF00675	0.320
CLV_PCSK_KEX2_1	24	26	PF00082	0.586
CLV_PCSK_KEX2_1	45	47	PF00082	0.224
CLV_PCSK_KEX2_1	9	11	PF00082	0.461
CLV_PCSK_PC1ET2_1	9	11	PF00082	0.477
CLV_Separin_Metazoa	13	17	PF03568	0.591
DOC_MAPK_gen_1	38	44	PF00069	0.460
DOC_PP4_FxxP_1	70	73	PF00568	0.413
DOC_USP7_UBL2_3	28	32	PF12436	0.570
DOC_WW_Pin1_4	47	52	PF00397	0.424
LIG_APCC_ABBA_1	49	54	PF00400	0.424
LIG_FHA_2	32	38	PF00498	0.514
LIG_LIR_Gen_1	50	60	PF02991	0.424
LIG_LIR_Nem_3	50	55	PF02991	0.424
LIG_SH2_STAT5	69	72	PF00017	0.425
LIG_SH3_4	72	79	PF00018	0.424
MOD_CK1_1	78	84	PF00069	0.437
MOD_CK2_1	91	97	PF00069	0.595
MOD_GlcNHglycan	64	68	PF01048	0.276
MOD_GlcNHglycan	86	89	PF01048	0.213
MOD_GlcNHglycan	93	96	PF01048	0.361
MOD_GSK3_1	19	26	PF00069	0.476
MOD_NEK2_1	14	19	PF00069	0.519
MOD_NEK2_1	23	28	PF00069	0.512
MOD_NEK2_2	19	24	PF00069	0.476
MOD_PIKK_1	1	7	PF00454	0.458
MOD_PIKK_1	78	84	PF00454	0.438
MOD_PKA_1	24	30	PF00069	0.540
MOD_PKA_2	23	29	PF00069	0.489
MOD_ProDKin_1	47	53	PF00069	0.424
MOD_SUMO_rev_2	33	40	PF00179	0.444
MOD_SUMO_rev_2	87	95	PF00179	0.413
TRG_ER_diArg_1	23	25	PF00400	0.554
TRG_ER_diArg_1	44	46	PF00400	0.517

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HWY6	Leptomonas seymouri	94%	100%
A0A0S4JL81	Bodo saltans	67%	89%
A0A1X0P4U0	Trypanosomatidae	75%	100%
A0A422MZD2	Trypanosoma rangeli	74%	100%
A2R091	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	41%	66%
A4HPP5	Leishmania braziliensis	98%	100%
A4ID19	Leishmania infantum	100%	100%
D0A8G9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	73%	100%
E9ATF9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
Q1DI23	Coccidioides immitis (strain RS)	43%	66%
Q2H4X9	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	37%	69%
Q4I283	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	38%	67%
Q4Q138	Leishmania major	99%	100%
Q54TR8	Dictyostelium discoideum	49%	73%
Q7SDU4	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	38%	68%
Q92371	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	33%	68%
V5BE97	Trypanosoma cruzi	74%	100%