LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7XBB0_LEIDO
TriTrypDb:
LdBPK_363530.1 , LdCL_360042300 , LDHU3_36.4810
Length:
102

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7XBB0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XBB0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 22 24 PF00675 0.436
CLV_NRD_NRD_1 40 42 PF00675 0.536
CLV_PCSK_KEX2_1 22 24 PF00082 0.439
CLV_PCSK_KEX2_1 39 41 PF00082 0.564
CLV_PCSK_KEX2_1 4 6 PF00082 0.468
CLV_PCSK_PC1ET2_1 4 6 PF00082 0.508
CLV_PCSK_SKI1_1 15 19 PF00082 0.411
CLV_PCSK_SKI1_1 27 31 PF00082 0.533
CLV_PCSK_SKI1_1 5 9 PF00082 0.467
DOC_USP7_MATH_1 28 32 PF00917 0.518
DOC_USP7_UBL2_3 11 15 PF12436 0.448
DOC_USP7_UBL2_3 4 8 PF12436 0.542
LIG_LIR_Nem_3 24 29 PF02991 0.526
LIG_Pex14_2 97 101 PF04695 0.431
LIG_SH2_CRK 26 30 PF00017 0.533
LIG_SH3_1 22 28 PF00018 0.399
LIG_SH3_3 22 28 PF00018 0.399
LIG_SH3_3 51 57 PF00018 0.552
LIG_SH3_3 92 98 PF00018 0.422
MOD_CK1_1 67 73 PF00069 0.492
MOD_GSK3_1 7 14 PF00069 0.522
MOD_PIKK_1 74 80 PF00454 0.522
MOD_SUMO_rev_2 43 50 PF00179 0.460
TRG_DiLeu_BaEn_2 50 56 PF01217 0.434
TRG_ENDOCYTIC_2 26 29 PF00928 0.526
TRG_ER_diArg_1 39 41 PF00400 0.522
TRG_ER_diArg_1 84 87 PF00400 0.433
TRG_Pf-PMV_PEXEL_1 40 44 PF00026 0.442

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PCP3 Leptomonas seymouri 85% 100%
A0A0S4JHJ6 Bodo saltans 47% 96%
A0A1X0P4C1 Trypanosomatidae 67% 100%
A0A3R7L800 Trypanosoma rangeli 68% 100%
A4HPK4 Leishmania braziliensis 93% 100%
A4ID60 Leishmania infantum 100% 100%
D0A8K9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 63% 100%
E9ATB6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 98% 100%
Q4Q181 Leishmania major 99% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS