Glycosyl_transferase-like_protein/GeneDB:LmjF.36. 3450

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

glycosyl transferase-like protein

Species:

Leishmania donovani

UniProt:

A0A3S7XB94_LEIDO

TriTrypDb:

LdBPK_363610.1 , LdCL_360043100 , LDHU3_36.4890

Length:

285

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 21
NetGPI	no	yes: 0, no: 21

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0110165	cellular anatomical entity	1	2
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1

Expansion

Sequence features

A0A3S7XB94

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XB94

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	22
GO:0016740	transferase activity	2	22

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	142	146	PF00656	0.348
CLV_NRD_NRD_1	168	170	PF00675	0.553
CLV_NRD_NRD_1	221	223	PF00675	0.490
CLV_NRD_NRD_1	28	30	PF00675	0.436
CLV_NRD_NRD_1	78	80	PF00675	0.539
CLV_PCSK_KEX2_1	168	170	PF00082	0.522
CLV_PCSK_KEX2_1	221	223	PF00082	0.466
CLV_PCSK_KEX2_1	28	30	PF00082	0.435
CLV_PCSK_KEX2_1	78	80	PF00082	0.543
CLV_PCSK_SKI1_1	221	225	PF00082	0.455
CLV_PCSK_SKI1_1	78	82	PF00082	0.464
CLV_PCSK_SKI1_1	95	99	PF00082	0.408
DEG_Nend_UBRbox_1	1	4	PF02207	0.536
DEG_SCF_TRCP1_1	148	153	PF00400	0.190
DOC_CKS1_1	214	219	PF01111	0.319
DOC_PP2B_LxvP_1	268	271	PF13499	0.395
DOC_USP7_MATH_1	156	160	PF00917	0.232
DOC_WW_Pin1_4	1	6	PF00397	0.690
DOC_WW_Pin1_4	121	126	PF00397	0.179
DOC_WW_Pin1_4	150	155	PF00397	0.237
DOC_WW_Pin1_4	213	218	PF00397	0.319
LIG_14-3-3_CanoR_1	14	19	PF00244	0.408
LIG_14-3-3_CanoR_1	168	174	PF00244	0.349
LIG_14-3-3_CanoR_1	222	232	PF00244	0.382
LIG_BRCT_BRCA1_1	12	16	PF00533	0.500
LIG_BRCT_BRCA1_1	158	162	PF00533	0.346
LIG_FHA_1	1	7	PF00498	0.535
LIG_FHA_1	229	235	PF00498	0.269
LIG_FHA_1	237	243	PF00498	0.298
LIG_FHA_1	48	54	PF00498	0.346
LIG_FHA_2	140	146	PF00498	0.237
LIG_LIR_Gen_1	176	185	PF02991	0.262
LIG_LIR_Gen_1	31	41	PF02991	0.293
LIG_LIR_Nem_3	176	180	PF02991	0.261
LIG_LIR_Nem_3	31	36	PF02991	0.305
LIG_Pex14_1	177	181	PF04695	0.247
LIG_SH2_STAT3	266	269	PF00017	0.339
LIG_SH2_STAT5	181	184	PF00017	0.264
LIG_SH2_STAT5	213	216	PF00017	0.223
LIG_SH2_STAT5	266	269	PF00017	0.347
LIG_SH3_3	155	161	PF00018	0.377
LIG_SH3_3	239	245	PF00018	0.483
LIG_SH3_3	257	263	PF00018	0.359
LIG_TRFH_1	266	270	PF08558	0.381
MOD_CDK_SPxxK_3	1	8	PF00069	0.491
MOD_CK1_1	118	124	PF00069	0.353
MOD_CK1_1	141	147	PF00069	0.339
MOD_GlcNHglycan	120	123	PF01048	0.437
MOD_GlcNHglycan	147	151	PF01048	0.580
MOD_GlcNHglycan	182	185	PF01048	0.488
MOD_GlcNHglycan	72	75	PF01048	0.437
MOD_GSK3_1	10	17	PF00069	0.563
MOD_GSK3_1	139	146	PF00069	0.391
MOD_GSK3_1	150	157	PF00069	0.232
MOD_GSK3_1	180	187	PF00069	0.266
MOD_N-GLC_1	118	123	PF02516	0.437
MOD_NEK2_1	223	228	PF00069	0.285
MOD_PK_1	169	175	PF00069	0.237
MOD_PKA_2	207	213	PF00069	0.258
MOD_Plk_1	138	144	PF00069	0.272
MOD_Plk_2-3	139	145	PF00069	0.237
MOD_ProDKin_1	1	7	PF00069	0.692
MOD_ProDKin_1	121	127	PF00069	0.179
MOD_ProDKin_1	150	156	PF00069	0.237
MOD_ProDKin_1	213	219	PF00069	0.319
TRG_DiLeu_BaLyEn_6	219	224	PF01217	0.272
TRG_ER_diArg_1	168	170	PF00400	0.349
TRG_ER_diArg_1	221	223	PF00400	0.290
TRG_ER_diArg_1	28	30	PF00400	0.237
TRG_ER_diArg_1	77	79	PF00400	0.308
TRG_Pf-PMV_PEXEL_1	78	82	PF00026	0.467

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P896	Leptomonas seymouri	35%	100%
A0A0N1PCD6	Leptomonas seymouri	60%	99%
A0A0S4IK22	Bodo saltans	32%	100%
A0A1X0NN04	Trypanosomatidae	32%	100%
A0A1X0P3F1	Trypanosomatidae	43%	83%
A0A3Q8I9N9	Leishmania donovani	32%	100%
A0A3R7K9Z6	Trypanosoma rangeli	47%	95%
A0A3R7MES7	Trypanosoma rangeli	34%	100%
A4H781	Leishmania braziliensis	32%	100%
A4HPL2	Leishmania braziliensis	86%	100%
A4HVM1	Leishmania infantum	32%	100%
A4ID52	Leishmania infantum	100%	100%
D0A6N3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	80%
D0A8K2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	47%	93%
E9APB7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9ATC4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
Q4Q173	Leishmania major	93%	100%
Q4QG61	Leishmania major	32%	100%
V5BK55	Trypanosoma cruzi	34%	100%
V5BS52	Trypanosoma cruzi	48%	94%