Small acidic protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Small acidic protein family, putative

Species:

Leishmania donovani

UniProt:

A0A3S7XB92_LEIDO

TriTrypDb:

LdBPK_363640.1 , LdCL_360043400 , LDHU3_36.4930

Length:

209

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7XB92

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XB92

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	100	102	PF00675	0.805
CLV_NRD_NRD_1	76	78	PF00675	0.620
CLV_PCSK_KEX2_1	147	149	PF00082	0.357
CLV_PCSK_KEX2_1	185	187	PF00082	0.430
CLV_PCSK_KEX2_1	57	59	PF00082	0.707
CLV_PCSK_KEX2_1	98	100	PF00082	0.691
CLV_PCSK_PC1ET2_1	147	149	PF00082	0.357
CLV_PCSK_PC1ET2_1	185	187	PF00082	0.515
CLV_PCSK_PC1ET2_1	57	59	PF00082	0.745
CLV_PCSK_PC1ET2_1	98	100	PF00082	0.691
CLV_PCSK_SKI1_1	147	151	PF00082	0.376
CLV_PCSK_SKI1_1	77	81	PF00082	0.569
DEG_SPOP_SBC_1	109	113	PF00917	0.723
DOC_USP7_MATH_1	109	113	PF00917	0.669
DOC_USP7_MATH_1	121	125	PF00917	0.477
DOC_USP7_MATH_1	79	83	PF00917	0.581
DOC_USP7_UBL2_3	74	78	PF12436	0.592
LIG_14-3-3_CanoR_1	173	178	PF00244	0.501
LIG_BRCT_BRCA1_1	137	141	PF00533	0.501
LIG_FHA_1	124	130	PF00498	0.637
LIG_FHA_1	14	20	PF00498	0.622
LIG_FHA_1	40	46	PF00498	0.518
LIG_PDZ_Class_2	204	209	PF00595	0.376
LIG_SUMO_SIM_anti_2	41	47	PF11976	0.544
LIG_TRAF2_1	105	108	PF00917	0.614
LIG_TRAF2_1	161	164	PF00917	0.326
LIG_TRAF2_1	35	38	PF00917	0.636
LIG_WRC_WIRS_1	1	6	PF05994	0.600
MOD_CK1_1	111	117	PF00069	0.700
MOD_CK1_1	124	130	PF00069	0.629
MOD_CK1_1	84	90	PF00069	0.702
MOD_CK2_1	102	108	PF00069	0.606
MOD_CK2_1	177	183	PF00069	0.397
MOD_CK2_1	190	196	PF00069	0.333
MOD_CK2_1	62	68	PF00069	0.630
MOD_Cter_Amidation	202	205	PF01082	0.376
MOD_GlcNHglycan	122	126	PF01048	0.689
MOD_GlcNHglycan	83	86	PF01048	0.711
MOD_GSK3_1	107	114	PF00069	0.690
MOD_GSK3_1	117	124	PF00069	0.510
MOD_GSK3_1	169	176	PF00069	0.388
MOD_GSK3_1	99	106	PF00069	0.768
MOD_LATS_1	171	177	PF00433	0.501
MOD_NEK2_1	177	182	PF00069	0.501
MOD_NEK2_1	197	202	PF00069	0.171
MOD_PIKK_1	190	196	PF00454	0.444
MOD_PIKK_1	62	68	PF00454	0.643
MOD_PKA_1	99	105	PF00069	0.729
MOD_PKA_2	115	121	PF00069	0.584
MOD_PKA_2	99	105	PF00069	0.741
MOD_Plk_2-3	103	109	PF00069	0.592
MOD_SUMO_rev_2	139	149	PF00179	0.426
MOD_SUMO_rev_2	180	187	PF00179	0.501
TRG_DiLeu_BaLyEn_6	46	51	PF01217	0.591
TRG_ER_diArg_1	99	101	PF00400	0.809
TRG_NES_CRM1_1	38	52	PF08389	0.590
TRG_NLS_MonoCore_2	97	102	PF00514	0.727
TRG_NLS_MonoExtC_3	97	103	PF00514	0.731
TRG_NLS_MonoExtN_4	97	102	PF00514	0.736
TRG_Pf-PMV_PEXEL_1	49	53	PF00026	0.543

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDM8	Leptomonas seymouri	55%	100%
A0A1X0P3N2	Trypanosomatidae	37%	100%
A4HPL5	Leishmania braziliensis	74%	100%
A4ID49	Leishmania infantum	100%	100%
E9ATC7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
Q4Q170	Leishmania major	89%	100%