F-box domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3S7XB84_LEIDO

TriTrypDb:

LdBPK_363770.1 , LdCL_360044700 , LDHU3_36.5080

Length:

537

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A0A3S7XB84

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XB84

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	429	433	PF00656	0.462
CLV_C14_Caspase3-7	473	477	PF00656	0.513
CLV_NRD_NRD_1	29	31	PF00675	0.594
CLV_PCSK_KEX2_1	200	202	PF00082	0.647
CLV_PCSK_PC1ET2_1	200	202	PF00082	0.647
CLV_PCSK_SKI1_1	131	135	PF00082	0.530
CLV_PCSK_SKI1_1	177	181	PF00082	0.593
CLV_PCSK_SKI1_1	394	398	PF00082	0.549
DEG_Nend_UBRbox_2	1	3	PF02207	0.443
DEG_ODPH_VHL_1	58	69	PF01847	0.404

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IJZ9	Leptomonas seymouri	60%	97%
A0A1X0P3D8	Trypanosomatidae	30%	100%
A4HPM8	Leishmania braziliensis	81%	100%
A4ID38	Leishmania infantum	100%	100%
E9ATE0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
Q4Q157	Leishmania major	92%	100%

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