LeishMANIAdb
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D-aminoacyl-tRNA deacylase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
D-aminoacyl-tRNA deacylase
Gene product:
D-tyrosyl-tRNA deacylase, putative
Species:
Leishmania donovani
UniProt:
A0A3S7XAZ2_LEIDO
TriTrypDb:
LdBPK_362870.1 * , LdCL_360035100 , LDHU3_36.3990
Length:
152

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
TermNameLevelCount
GO:0005737 cytoplasm 2 11
GO:0110165 cellular anatomical entity 1 11
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Expansion

Sequence features

A0A3S7XAZ2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XAZ2

Function

Biological processes
TermNameLevelCount
GO:0006139 nucleobase-containing compound metabolic process 3 1
GO:0006399 tRNA metabolic process 7 1
GO:0006725 cellular aromatic compound metabolic process 3 1
GO:0006807 nitrogen compound metabolic process 2 1
GO:0008152 metabolic process 1 1
GO:0009987 cellular process 1 1
GO:0016070 RNA metabolic process 5 1
GO:0034641 cellular nitrogen compound metabolic process 3 1
GO:0034660 ncRNA metabolic process 6 1
GO:0043170 macromolecule metabolic process 3 1
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Molecular functions
TermNameLevelCount
GO:0000049 tRNA binding 5 11
GO:0002161 aminoacyl-tRNA editing activity 5 11
GO:0003676 nucleic acid binding 3 11
GO:0003723 RNA binding 4 11
GO:0003824 catalytic activity 1 11
GO:0005488 binding 1 11
GO:0016787 hydrolase activity 2 11
GO:0016788 hydrolase activity, acting on ester bonds 3 11
GO:0051499 D-aminoacyl-tRNA deacylase activity 6 11
GO:0051500 D-tyrosyl-tRNA(Tyr) deacylase activity 7 1
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 46 48 PF00675 0.263
CLV_PCSK_KEX2_1 150 152 PF00082 0.638
CLV_PCSK_PC1ET2_1 150 152 PF00082 0.638
CLV_PCSK_SKI1_1 122 126 PF00082 0.282
CLV_PCSK_SKI1_1 47 51 PF00082 0.267
CLV_PCSK_SKI1_1 66 70 PF00082 0.263
DEG_Nend_UBRbox_1 1 4 PF02207 0.286
DOC_MAPK_gen_1 47 54 PF00069 0.454
DOC_MAPK_MEF2A_6 25 33 PF00069 0.463
DOC_MAPK_MEF2A_6 47 54 PF00069 0.454
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Homologs

ProteinTaxonomySequence identityCoverage
A0A023W421 Bacillus amyloliquefaciens 42% 100%
A0A0N1PFD2 Leptomonas seymouri 83% 100%
A0A1X0NK85 Trypanosomatidae 64% 100%
A0A1X0NKG6 Trypanosomatidae 65% 100%
A0A422MUI5 Trypanosoma rangeli 61% 100%
A0AIX1 Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / CIP 8149 / NCTC 11857 / SLCC 5334 / V8) 36% 100%
A0K4L0 Burkholderia cenocepacia (strain HI2424) 38% 100%
A0KEZ2 Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049) 39% 100%
A0KRY8 Shewanella sp. (strain ANA-3) 38% 100%
A0L7S8 Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1) 41% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS