Caltractin_putative/GeneDB:LmjF.36.2430

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

caltractin, putative

Species:

Leishmania donovani

UniProt:

A0A3S7XAY6_LEIDO

TriTrypDb:

LdBPK_362560.1 , LdCL_360031600 , LDHU3_36.3510

Length:

239

Annotations

Annotations by Jardim et al.

Structural Proteins, caltractin

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3S7XAY6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XAY6

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	2
GO:0005509	calcium ion binding	5	2
GO:0043167	ion binding	2	2
GO:0043169	cation binding	3	2
GO:0046872	metal ion binding	4	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	67	71	PF00656	0.630
CLV_NRD_NRD_1	156	158	PF00675	0.439
CLV_NRD_NRD_1	190	192	PF00675	0.413
CLV_NRD_NRD_1	233	235	PF00675	0.435
CLV_PCSK_KEX2_1	190	192	PF00082	0.430
CLV_PCSK_SKI1_1	157	161	PF00082	0.589
DEG_APCC_DBOX_1	17	25	PF00400	0.503
DEG_Nend_UBRbox_3	1	3	PF02207	0.499
DOC_CKS1_1	104	109	PF01111	0.538
DOC_MAPK_gen_1	15	24	PF00069	0.508
DOC_PP1_RVXF_1	21	28	PF00149	0.477
DOC_PP4_FxxP_1	132	135	PF00568	0.619
DOC_SPAK_OSR1_1	75	79	PF12202	0.584
DOC_USP7_MATH_1	105	109	PF00917	0.545
DOC_USP7_MATH_1	119	123	PF00917	0.493
DOC_USP7_MATH_1	125	129	PF00917	0.460
DOC_WW_Pin1_4	103	108	PF00397	0.602
DOC_WW_Pin1_4	117	122	PF00397	0.569
DOC_WW_Pin1_4	131	136	PF00397	0.500
DOC_WW_Pin1_4	96	101	PF00397	0.747
LIG_14-3-3_CanoR_1	15	25	PF00244	0.506
LIG_14-3-3_CanoR_1	6	12	PF00244	0.493
LIG_FHA_1	169	175	PF00498	0.397
LIG_FHA_1	216	222	PF00498	0.395
LIG_FHA_2	199	205	PF00498	0.449
LIG_FHA_2	223	229	PF00498	0.391
LIG_FHA_2	65	71	PF00498	0.721
LIG_LIR_Gen_1	149	159	PF02991	0.424
LIG_LIR_Gen_1	171	180	PF02991	0.431
LIG_LIR_Gen_1	224	233	PF02991	0.400
LIG_LIR_Nem_3	149	154	PF02991	0.432
LIG_LIR_Nem_3	171	175	PF02991	0.428
LIG_LIR_Nem_3	177	183	PF02991	0.439
LIG_LIR_Nem_3	207	212	PF02991	0.417
LIG_LIR_Nem_3	224	229	PF02991	0.424
LIG_Rb_pABgroove_1	203	211	PF01858	0.410
LIG_SH2_STAP1	164	168	PF00017	0.399
LIG_SH2_STAP1	170	174	PF00017	0.400
LIG_SH2_STAT5	170	173	PF00017	0.456
LIG_SH2_STAT5	9	12	PF00017	0.494
LIG_SH3_3	115	121	PF00018	0.706
LIG_TRAF2_1	163	166	PF00917	0.395
LIG_WRC_WIRS_1	223	228	PF05994	0.387
MOD_CK1_1	134	140	PF00069	0.633
MOD_CK1_1	224	230	PF00069	0.424
MOD_CK1_1	52	58	PF00069	0.634
MOD_CK1_1	59	65	PF00069	0.688
MOD_CK1_1	79	85	PF00069	0.618
MOD_CK1_1	91	97	PF00069	0.636
MOD_CK1_1	99	105	PF00069	0.719
MOD_CK2_1	160	166	PF00069	0.408
MOD_CK2_1	198	204	PF00069	0.464
MOD_CK2_1	91	97	PF00069	0.634
MOD_GlcNHglycan	112	115	PF01048	0.699
MOD_GlcNHglycan	121	124	PF01048	0.568
MOD_GlcNHglycan	55	58	PF01048	0.631
MOD_GSK3_1	119	126	PF00069	0.471
MOD_GSK3_1	211	218	PF00069	0.415
MOD_GSK3_1	45	52	PF00069	0.600
MOD_GSK3_1	59	66	PF00069	0.654
MOD_GSK3_1	76	83	PF00069	0.620
MOD_GSK3_1	91	98	PF00069	0.669
MOD_GSK3_1	99	106	PF00069	0.633
MOD_N-GLC_1	91	96	PF02516	0.573
MOD_NEK2_1	168	173	PF00069	0.392
MOD_NEK2_1	76	81	PF00069	0.603
MOD_PIKK_1	125	131	PF00454	0.658
MOD_PIKK_1	45	51	PF00454	0.548
MOD_PIKK_1	59	65	PF00454	0.620
MOD_PIKK_1	99	105	PF00454	0.605
MOD_PKA_2	80	86	PF00069	0.611
MOD_PKA_2	95	101	PF00069	0.510
MOD_Plk_1	176	182	PF00069	0.446
MOD_Plk_1	221	227	PF00069	0.384
MOD_Plk_1	63	69	PF00069	0.563
MOD_Plk_1	71	77	PF00069	0.552
MOD_Plk_1	91	97	PF00069	0.478
MOD_Plk_2-3	198	204	PF00069	0.439
MOD_Plk_2-3	222	228	PF00069	0.387
MOD_Plk_2-3	64	70	PF00069	0.539
MOD_ProDKin_1	103	109	PF00069	0.602
MOD_ProDKin_1	117	123	PF00069	0.569
MOD_ProDKin_1	131	137	PF00069	0.500
MOD_ProDKin_1	96	102	PF00069	0.746
TRG_DiLeu_BaEn_1	20	25	PF01217	0.423
TRG_ENDOCYTIC_2	180	183	PF00928	0.402
TRG_ER_diArg_1	189	191	PF00400	0.408

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5G8	Leptomonas seymouri	51%	100%
A4HPA9	Leishmania braziliensis	70%	97%
A4ICE9	Leishmania infantum	100%	100%
E9AT20	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
Q4Q1H8	Leishmania major	87%	100%