Serine/threonine_protein_phosphatase_2B_catalytic _subunit_A2_putative/GeneDB:LmjF.36.1980

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

serine/threonine protein phosphatase 2B catalytic subunit A2, putative

Species:

Leishmania donovani

UniProt:

A0A3S7XAY3_LEIDO

TriTrypDb:

LdBPK_362090.1 , LdCL_360026400 , LDHU3_36.2710

Length:

407

Annotations

LeishMANIAdb annotations

A large collection of various protein phosphatases. Very highly expanded in kinetoplastids.

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 18
NetGPI	no	yes: 0, no: 18

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0005955	calcineurin complex	3	2
GO:0008287	protein serine/threonine phosphatase complex	4	2
GO:0032991	protein-containing complex	1	2
GO:0110165	cellular anatomical entity	1	2
GO:0140535	intracellular protein-containing complex	2	2
GO:1902494	catalytic complex	2	2
GO:1903293	phosphatase complex	3	2

Expansion

Sequence features

A0A3S7XAY3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XAY3

Function

Biological processes
Term	Name	Level	Count
GO:0007165	signal transduction	2	19
GO:0009987	cellular process	1	19
GO:0019722	calcium-mediated signaling	5	19
GO:0019932	second-messenger-mediated signaling	4	19
GO:0035556	intracellular signal transduction	3	19
GO:0050789	regulation of biological process	2	19
GO:0050794	regulation of cellular process	3	19
GO:0065007	biological regulation	1	19
GO:0097720	calcineurin-mediated signaling	6	19

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	19
GO:0004721	phosphoprotein phosphatase activity	3	19
GO:0004722	protein serine/threonine phosphatase activity	4	19
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	5	19
GO:0016787	hydrolase activity	2	19
GO:0016788	hydrolase activity, acting on ester bonds	3	19
GO:0016791	phosphatase activity	5	19
GO:0017018	myosin phosphatase activity	5	18
GO:0033192	calmodulin-dependent protein phosphatase activity	6	19
GO:0042578	phosphoric ester hydrolase activity	4	19
GO:0140096	catalytic activity, acting on a protein	2	19
GO:0005488	binding	1	7
GO:0005515	protein binding	2	7
GO:0005516	calmodulin binding	3	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	182	184	PF00675	0.318
CLV_PCSK_KEX2_1	277	279	PF00082	0.422
CLV_PCSK_PC1ET2_1	277	279	PF00082	0.422
CLV_PCSK_SKI1_1	103	107	PF00082	0.340
CLV_PCSK_SKI1_1	184	188	PF00082	0.341
CLV_PCSK_SKI1_1	256	260	PF00082	0.352
CLV_PCSK_SKI1_1	357	361	PF00082	0.571
DOC_PP4_FxxP_1	317	320	PF00568	0.313
DOC_USP7_MATH_1	10	14	PF00917	0.493
DOC_USP7_MATH_1	195	199	PF00917	0.337
DOC_USP7_MATH_1	389	393	PF00917	0.553
DOC_USP7_MATH_1	95	99	PF00917	0.318
DOC_WW_Pin1_4	191	196	PF00397	0.304
DOC_WW_Pin1_4	345	350	PF00397	0.412
DOC_WW_Pin1_4	401	406	PF00397	0.717
LIG_14-3-3_CanoR_1	23	27	PF00244	0.624
LIG_14-3-3_CanoR_1	265	270	PF00244	0.315
LIG_14-3-3_CanoR_1	278	286	PF00244	0.315
LIG_14-3-3_CanoR_1	357	363	PF00244	0.434
LIG_Actin_WH2_2	144	162	PF00022	0.318
LIG_BIR_II_1	1	5	PF00653	0.546
LIG_BRCT_BRCA1_1	267	271	PF00533	0.268
LIG_BRCT_BRCA1_1	362	366	PF00533	0.421
LIG_deltaCOP1_diTrp_1	220	228	PF00928	0.293
LIG_FHA_1	100	106	PF00498	0.328
LIG_FHA_1	253	259	PF00498	0.422
LIG_FHA_1	67	73	PF00498	0.454
LIG_FHA_2	17	23	PF00498	0.695
LIG_FHA_2	385	391	PF00498	0.514
LIG_LIR_Apic_2	220	226	PF02991	0.311
LIG_LIR_Apic_2	315	320	PF02991	0.289
LIG_LIR_Apic_2	361	365	PF02991	0.474
LIG_LIR_Gen_1	101	111	PF02991	0.280
LIG_LIR_Gen_1	171	181	PF02991	0.339
LIG_LIR_Gen_1	373	379	PF02991	0.432
LIG_LIR_Nem_3	101	107	PF02991	0.280
LIG_LIR_Nem_3	171	176	PF02991	0.335
LIG_LIR_Nem_3	296	302	PF02991	0.394
LIG_LIR_Nem_3	339	345	PF02991	0.490
LIG_LIR_Nem_3	373	378	PF02991	0.465
LIG_MYND_3	364	368	PF01753	0.518
LIG_Pex14_1	362	366	PF04695	0.413
LIG_PTB_Apo_2	110	117	PF02174	0.393
LIG_SH2_CRK	87	91	PF00017	0.305
LIG_SH2_NCK_1	235	239	PF00017	0.422
LIG_SH2_STAP1	161	165	PF00017	0.362
LIG_SH2_STAP1	51	55	PF00017	0.445
LIG_SH2_STAT5	104	107	PF00017	0.299
LIG_SH2_STAT5	110	113	PF00017	0.300
LIG_SH2_STAT5	246	249	PF00017	0.309
LIG_SH2_STAT5	269	272	PF00017	0.326
LIG_SH2_STAT5	322	325	PF00017	0.397
LIG_SH3_3	126	132	PF00018	0.405
LIG_SH3_3	235	241	PF00018	0.311
LIG_SUMO_SIM_anti_2	201	207	PF11976	0.345
LIG_SUMO_SIM_anti_2	74	81	PF11976	0.295
LIG_SUMO_SIM_par_1	312	318	PF11976	0.363
LIG_SUMO_SIM_par_1	331	336	PF11976	0.213
LIG_SUMO_SIM_par_1	68	75	PF11976	0.344
LIG_UBA3_1	121	128	PF00899	0.342
MOD_CK1_1	141	147	PF00069	0.422
MOD_CK1_1	191	197	PF00069	0.422
MOD_CK1_1	242	248	PF00069	0.346
MOD_CK1_1	315	321	PF00069	0.298
MOD_CK1_1	336	342	PF00069	0.483
MOD_CK1_1	98	104	PF00069	0.409
MOD_CK2_1	16	22	PF00069	0.719
MOD_CK2_1	394	400	PF00069	0.763
MOD_GlcNHglycan	170	173	PF01048	0.433
MOD_GlcNHglycan	190	193	PF01048	0.182
MOD_GlcNHglycan	239	244	PF01048	0.371
MOD_GlcNHglycan	280	283	PF01048	0.422
MOD_GlcNHglycan	317	320	PF01048	0.313
MOD_GlcNHglycan	379	382	PF01048	0.547
MOD_GlcNHglycan	8	11	PF01048	0.678
MOD_GSK3_1	191	198	PF00069	0.328
MOD_GSK3_1	366	373	PF00069	0.490
MOD_GSK3_1	389	396	PF00069	0.709
MOD_GSK3_1	6	13	PF00069	0.613
MOD_GSK3_1	62	69	PF00069	0.387
MOD_GSK3_1	95	102	PF00069	0.386
MOD_N-GLC_1	141	146	PF02516	0.401
MOD_N-GLC_1	16	21	PF02516	0.707
MOD_N-GLC_1	72	77	PF02516	0.450
MOD_N-GLC_2	321	323	PF02516	0.362
MOD_NEK2_1	159	164	PF00069	0.434
MOD_NEK2_1	16	21	PF00069	0.652
MOD_NEK2_1	252	257	PF00069	0.303
MOD_NEK2_1	258	263	PF00069	0.387
MOD_NEK2_1	360	365	PF00069	0.417
MOD_NEK2_1	366	371	PF00069	0.404
MOD_NEK2_1	99	104	PF00069	0.352
MOD_NEK2_2	312	317	PF00069	0.322
MOD_PKA_2	138	144	PF00069	0.399
MOD_PKA_2	22	28	PF00069	0.645
MOD_Plk_1	16	22	PF00069	0.580
MOD_Plk_1	195	201	PF00069	0.321
MOD_Plk_1	72	78	PF00069	0.346
MOD_Plk_4	131	137	PF00069	0.351
MOD_Plk_4	161	167	PF00069	0.333
MOD_Plk_4	242	248	PF00069	0.318
MOD_Plk_4	265	271	PF00069	0.316
MOD_Plk_4	370	376	PF00069	0.404
MOD_Plk_4	72	78	PF00069	0.431
MOD_ProDKin_1	191	197	PF00069	0.304
MOD_ProDKin_1	345	351	PF00069	0.415
MOD_ProDKin_1	401	407	PF00069	0.705
MOD_SUMO_rev_2	141	147	PF00179	0.415
MOD_SUMO_rev_2	28	33	PF00179	0.509
TRG_DiLeu_BaEn_2	118	124	PF01217	0.382
TRG_DiLeu_BaLyEn_6	402	407	PF01217	0.475
TRG_ENDOCYTIC_2	104	107	PF00928	0.304
TRG_ENDOCYTIC_2	235	238	PF00928	0.400
TRG_ENDOCYTIC_2	86	89	PF00928	0.311

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7S7	Leptomonas seymouri	32%	100%
A0A0N0P7Y2	Leptomonas seymouri	38%	74%
A0A0N1HSR2	Leptomonas seymouri	31%	100%
A0A0N1I0V3	Leptomonas seymouri	29%	100%
A0A0N1IBK9	Leptomonas seymouri	31%	100%
A0A0N1ILH2	Leptomonas seymouri	79%	96%
A0A0N1P9X9	Leptomonas seymouri	29%	100%
A0A0N1PAV9	Leptomonas seymouri	30%	100%
A0A0N1PBN9	Leptomonas seymouri	30%	87%
A0A0N1PCC5	Leptomonas seymouri	31%	100%
A0A0N1PD03	Leptomonas seymouri	22%	92%
A0A0N1PDK9	Leptomonas seymouri	30%	100%
A0A0S4IIW0	Bodo saltans	47%	100%
A0A0S4ILF8	Bodo saltans	31%	100%
A0A0S4IS15	Bodo saltans	30%	84%
A0A0S4IYE4	Bodo saltans	25%	73%
A0A0S4J1J1	Bodo saltans	29%	100%
A0A0S4J323	Bodo saltans	31%	71%
A0A0S4JDD1	Bodo saltans	40%	90%
A0A0S4JEU6	Bodo saltans	31%	86%
A0A0S4JJ52	Bodo saltans	30%	100%
A0A0S4JJ96	Bodo saltans	31%	100%
A0A0S4JJH3	Bodo saltans	29%	100%
A0A0S4JKZ6	Bodo saltans	40%	82%
A0A0S4KGD7	Bodo saltans	30%	100%
A0A0S4KKU2	Bodo saltans	31%	100%
A0A0S4KLF4	Bodo saltans	28%	99%
A0A1X0NJI7	Trypanosomatidae	29%	73%
A0A1X0NK88	Trypanosomatidae	30%	100%
A0A1X0NMS7	Trypanosomatidae	25%	99%
A0A1X0NNN6	Trypanosomatidae	30%	100%
A0A1X0NS37	Trypanosomatidae	29%	100%
A0A1X0NS65	Trypanosomatidae	29%	100%
A0A1X0NUA6	Trypanosomatidae	30%	100%
A0A1X0NYR5	Trypanosomatidae	32%	100%
A0A1X0P6J3	Trypanosomatidae	39%	100%
A0A1X0P6Y9	Trypanosomatidae	30%	86%
A0A1X0P7H9	Trypanosomatidae	34%	91%
A0A1X0P7Q5	Trypanosomatidae	50%	100%
A0A1X0P982	Trypanosomatidae	29%	100%
A0A1X0P9R6	Trypanosomatidae	27%	90%
A0A1X0PA67	Trypanosomatidae	28%	100%
A0A1X0PAK9	Trypanosomatidae	28%	100%
A0A1X0PBJ2	Trypanosomatidae	32%	100%
A0A3Q8I8M6	Leishmania donovani	31%	100%
A0A3Q8ID20	Leishmania donovani	39%	100%
A0A3Q8IFB2	Leishmania donovani	29%	100%
A0A3Q8IH18	Leishmania donovani	31%	100%
A0A3Q8II54	Leishmania donovani	31%	69%
A0A3R7KQR6	Trypanosoma rangeli	30%	100%
A0A3R7LPS5	Trypanosoma rangeli	24%	98%
A0A3R7M399	Trypanosoma rangeli	27%	94%
A0A3R7MBA3	Trypanosoma rangeli	36%	91%
A0A3R7MFZ7	Trypanosoma rangeli	30%	100%
A0A3R7MM48	Trypanosoma rangeli	29%	100%
A0A3R7N275	Trypanosoma rangeli	33%	100%
A0A3R7NP99	Trypanosoma rangeli	31%	100%
A0A3S5H6K2	Leishmania donovani	22%	100%
A0A3S5H6T9	Leishmania donovani	29%	100%
A0A3S5H7Q6	Leishmania donovani	32%	100%
A0A3S7WUR2	Leishmania donovani	30%	100%
A0A3S7WZ39	Leishmania donovani	29%	95%
A0A3S7X190	Leishmania donovani	32%	90%
A0A3S7X1Y0	Leishmania donovani	30%	100%
A0A3S7X7I6	Leishmania donovani	29%	100%
A0A3S7X7J8	Leishmania donovani	29%	100%
A0A3S7X7K2	Leishmania donovani	29%	100%
A0A3S7X8K6	Leishmania donovani	31%	97%
A0A422N1U7	Trypanosoma rangeli	30%	68%
A0A422N8P1	Trypanosoma rangeli	28%	100%
A0A422N9D5	Trypanosoma rangeli	49%	100%
A0A422NKG0	Trypanosoma rangeli	26%	100%
A0A422NPG1	Trypanosoma rangeli	32%	100%
A0A422NWG6	Trypanosoma rangeli	29%	86%
A0A422NYN7	Trypanosoma rangeli	30%	100%
A0A422P483	Trypanosoma rangeli	30%	96%
A0C1E4	Paramecium tetraurelia	34%	100%
A0CCD2	Paramecium tetraurelia	34%	100%
A0CNL9	Paramecium tetraurelia	29%	100%
A0DJ90	Paramecium tetraurelia	32%	100%
A2X2G3	Oryza sativa subsp. indica	32%	100%
A2XN40	Oryza sativa subsp. indica	31%	100%
A2YEB4	Oryza sativa subsp. indica	32%	100%
A3C4N5	Oryza sativa subsp. japonica	31%	100%
A4H6S0	Leishmania braziliensis	22%	100%
A4H7D2	Leishmania braziliensis	31%	75%
A4H7E7	Leishmania braziliensis	31%	70%
A4H7Z3	Leishmania braziliensis	29%	100%
A4H9C0	Leishmania braziliensis	31%	100%
A4HAI7	Leishmania braziliensis	29%	100%
A4HAI8	Leishmania braziliensis	29%	100%
A4HAI9	Leishmania braziliensis	29%	100%
A4HAJ8	Leishmania braziliensis	30%	100%
A4HBE2	Leishmania braziliensis	31%	100%
A4HF98	Leishmania braziliensis	37%	100%
A4HGA9	Leishmania braziliensis	32%	90%
A4HGX0	Leishmania braziliensis	31%	100%
A4HJQ1	Leishmania braziliensis	32%	100%
A4HKU9	Leishmania braziliensis	31%	100%
A4HP65	Leishmania braziliensis	87%	100%
A4HV49	Leishmania infantum	22%	100%
A4HVT0	Leishmania infantum	31%	100%
A4HVT6	Leishmania infantum	31%	69%
A4HWC1	Leishmania infantum	29%	100%
A4HXP1	Leishmania infantum	30%	100%
A4I1H6	Leishmania infantum	29%	95%
A4I2J0	Leishmania infantum	39%	100%
A4I3E3	Leishmania infantum	32%	90%
A4I400	Leishmania infantum	30%	100%
A4I768	Leishmania infantum	32%	100%
A4I8C8	Leishmania infantum	31%	100%
A4I9P2	Leishmania infantum	29%	100%
A4IAJ0	Leishmania infantum	31%	97%
A4IDH0	Leishmania infantum	100%	100%
A6H772	Bos taurus	34%	100%
A8WGP3	Danio rerio	35%	100%
A8XE00	Caenorhabditis briggsae	34%	100%
A9JRC7	Danio rerio	35%	100%
B0XUR7	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	34%	75%
C9ZJZ6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	100%
C9ZM48	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	96%
C9ZMF3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	100%
C9ZN02	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	100%
C9ZN06	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	100%
C9ZQD6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	91%
C9ZWN3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	100%
C9ZX13	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	94%
D0A019	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	86%
D0A358	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	100%
D0A805	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	100%
D0A970	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	100%
D0AAU4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	100%
E9AHS8	Leishmania infantum	30%	95%
E9AHS9	Leishmania infantum	30%	100%
E9AHT0	Leishmania infantum	29%	100%
E9AHT1	Leishmania infantum	29%	100%
E9ANT1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9APH5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9API1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	69%
E9AQ21	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9ARF2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9ASX3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
E9AXL1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	95%
E9AYN4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	37%	100%
E9AZN0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	90%
E9B090	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9B262	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9B387	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9B4P8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9B4P9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9B4Q0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9B4Q1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9B4Q6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9B5L4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	97%
G5EGK8	Caenorhabditis elegans	30%	100%
O00743	Homo sapiens	33%	100%
O02658	Caenorhabditis elegans	28%	100%
O04856	Nicotiana tabacum	31%	100%
O04857	Nicotiana tabacum	32%	100%
O04858	Nicotiana tabacum	32%	100%
O04860	Nicotiana tabacum	30%	100%
O04951	Arabidopsis thaliana	32%	100%
O15757	Dictyostelium discoideum	33%	100%
O43049	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	86%
O74789	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	30%	100%
O76932	Drosophila melanogaster	35%	100%
O82733	Arabidopsis thaliana	34%	100%
O82734	Arabidopsis thaliana	32%	100%
P0C5D7	Oryza sativa subsp. indica	31%	100%
P11084	Oryctolagus cuniculus	33%	100%
P11493	Sus scrofa	30%	100%
P11611	Oryctolagus cuniculus	30%	100%
P11612	Drosophila melanogaster	32%	100%
P12982	Drosophila melanogaster	33%	100%
P13681	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	31%	100%
P14747	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	67%
P16298	Homo sapiens	37%	78%
P20604	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	32%	100%
P20651	Rattus norvegicus	37%	78%
P20654	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	33%	100%
P22198	Zea mays	30%	100%
P23287	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	74%
P23594	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	30%	100%
P23595	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	30%	100%
P23635	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	31%	100%
P23636	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	31%	100%
P23696	Drosophila melanogaster	29%	100%
P23733	Trypanosoma brucei brucei	31%	100%
P23734	Trypanosoma brucei brucei	31%	100%
P23778	Brassica napus	29%	100%
P23880	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	33%	100%
P30366	Arabidopsis thaliana	31%	100%
P32345	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	31%	100%
P32598	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	32%	100%
P32838	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	33%	100%
P32945	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	33%	74%
P34350	Caenorhabditis elegans	23%	100%
P36614	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	31%	100%
P36873	Homo sapiens	34%	100%
P36874	Xenopus laevis	32%	100%
P48452	Bos taurus	36%	78%
P48453	Mus musculus	37%	78%
P48454	Homo sapiens	35%	79%
P48455	Mus musculus	33%	79%
P48457	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	36%	74%
P48458	Caenorhabditis elegans	28%	100%
P48459	Caenorhabditis elegans	26%	90%
P48460	Caenorhabditis elegans	27%	90%
P48461	Drosophila melanogaster	33%	100%
P48462	Drosophila melanogaster	33%	100%
P48463	Gallus gallus	30%	100%
P48480	Acetabularia peniculus	32%	100%
P48481	Acetabularia peniculus	33%	100%
P48482	Arabidopsis thaliana	33%	100%
P48483	Arabidopsis thaliana	32%	100%
P48484	Arabidopsis thaliana	31%	100%
P48485	Arabidopsis thaliana	32%	100%
P48486	Arabidopsis thaliana	31%	100%
P48487	Brassica oleracea	32%	100%
P48488	Medicago sativa subsp. varia	31%	100%
P48489	Oryza sativa subsp. japonica	32%	100%
P48490	Phaseolus vulgaris	31%	100%
P48528	Arabidopsis thaliana	33%	100%
P48529	Arabidopsis thaliana	33%	100%
P48577	Acetabularia peniculus	32%	100%
P48578	Arabidopsis thaliana	30%	100%
P48579	Helianthus annuus	32%	100%
P48580	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	30%	100%
P48726	Paramecium tetraurelia	29%	100%
P48727	Caenorhabditis elegans	31%	100%
P49576	Paramecium tetraurelia	33%	100%
P53041	Homo sapiens	31%	82%
P53042	Rattus norvegicus	30%	82%
P53043	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	79%
P60510	Homo sapiens	34%	100%
P61287	Bos taurus	34%	100%
P61292	Sus scrofa	31%	100%
P62136	Homo sapiens	33%	100%
P62137	Mus musculus	33%	100%
P62138	Rattus norvegicus	33%	100%
P62139	Oryctolagus cuniculus	33%	100%
P62140	Homo sapiens	31%	100%
P62141	Mus musculus	31%	100%
P62142	Rattus norvegicus	31%	100%
P62143	Oryctolagus cuniculus	31%	100%
P62207	Gallus gallus	31%	100%
P62714	Homo sapiens	30%	100%
P62715	Mus musculus	30%	100%
P62716	Rattus norvegicus	30%	100%
P63087	Mus musculus	34%	100%
P63088	Rattus norvegicus	34%	100%
P63328	Mus musculus	36%	78%
P63329	Rattus norvegicus	36%	78%
P63330	Mus musculus	29%	100%
P63331	Rattus norvegicus	29%	100%
P67774	Bos taurus	29%	100%
P67775	Homo sapiens	29%	100%
P67776	Sus scrofa	29%	100%
P67777	Oryctolagus cuniculus	29%	100%
P78968	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	79%
P91420	Caenorhabditis elegans	28%	100%
P97470	Mus musculus	34%	100%
Q05547	Drosophila melanogaster	33%	100%
Q05681	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	38%	73%
Q06009	Medicago sativa	30%	100%
Q07098	Arabidopsis thaliana	32%	100%
Q07099	Arabidopsis thaliana	32%	100%
Q07100	Arabidopsis thaliana	29%	100%
Q08209	Homo sapiens	36%	78%
Q09496	Caenorhabditis elegans	30%	100%
Q0DBD3	Oryza sativa subsp. japonica	32%	100%
Q0E2S4	Oryza sativa subsp. japonica	32%	100%
Q0G819	Caenorhabditis elegans	36%	75%
Q0P594	Bos taurus	30%	100%
Q10298	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	100%
Q10BT5	Oryza sativa subsp. japonica	31%	100%
Q12705	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	36%	73%
Q27497	Caenorhabditis elegans	31%	100%
Q27884	Drosophila melanogaster	32%	100%
Q27889	Drosophila melanogaster	36%	71%
Q3SWW9	Bos taurus	31%	100%
Q3T0E7	Bos taurus	33%	100%
Q4Q1M5	Leishmania major	95%	100%
Q4Q2C2	Leishmania major	31%	97%
Q4Q3C0	Leishmania major	29%	100%
Q4Q3C5	Leishmania major	29%	100%
Q4Q3C6	Leishmania major	29%	100%
Q4Q3C7	Leishmania major	29%	100%
Q4Q3C8	Leishmania major	29%	100%
Q4Q4W8	Leishmania major	31%	100%
Q4Q5Z8	Leishmania major	32%	100%
Q4Q7Z5	Leishmania major	29%	100%
Q4Q8K1	Leishmania major	32%	90%
Q4Q8T8	Leishmania major	39%	100%
Q4Q9W1	Leishmania major	29%	95%
Q4QE27	Leishmania major	30%	100%
Q4QFG0	Leishmania major	29%	100%
Q4QFZ7	Leishmania major	32%	69%
Q4QG03	Leishmania major	30%	100%
Q4QGT8	Leishmania major	23%	100%
Q4WUR1	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	37%	76%
Q54RD6	Dictyostelium discoideum	33%	100%
Q59KY8	Candida albicans (strain SC5314 / ATCC MYA-2876)	33%	100%
Q5A6B6	Candida albicans (strain SC5314 / ATCC MYA-2876)	36%	98%
Q5BJ92	Rattus norvegicus	34%	100%
Q5I085	Xenopus tropicalis	31%	100%
Q5R6K8	Pongo abelii	34%	100%
Q5R740	Pongo abelii	31%	100%
Q60676	Mus musculus	30%	82%
Q61JR3	Caenorhabditis briggsae	31%	100%
Q627N3	Caenorhabditis briggsae	31%	100%
Q64620	Rattus norvegicus	33%	100%
Q6BFF6	Paramecium tetraurelia	31%	100%
Q6CNT6	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	31%	100%
Q6FM81	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	30%	100%
Q6GQL2	Xenopus laevis	31%	100%
Q6IP91	Xenopus laevis	35%	100%
Q6NVU2	Xenopus tropicalis	32%	100%
Q6P861	Xenopus tropicalis	35%	100%
Q74ZR2	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	30%	100%
Q7SZ10	Xenopus laevis	32%	100%
Q84K11	Solanum lycopersicum	33%	73%
Q84XU2	Arabidopsis thaliana	33%	76%
Q8LSN3	Pisum sativum	32%	100%
Q8MJ46	Canis lupus familiaris	34%	100%
Q8MJ47	Canis lupus familiaris	31%	100%
Q8WMS6	Canis lupus familiaris	33%	100%
Q8X178	Blumeria hordei	29%	100%
Q9CQR6	Mus musculus	33%	100%
Q9FN02	Arabidopsis thaliana	28%	99%
Q9HFQ2	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	29%	100%
Q9LHE7	Arabidopsis thaliana	33%	100%
Q9M9W3	Arabidopsis thaliana	32%	100%
Q9NES8	Caenorhabditis elegans	26%	82%
Q9SX52	Arabidopsis thaliana	33%	100%
Q9U9A3	Dictyostelium discoideum	31%	100%
Q9UW86	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	32%	100%
Q9VXF1	Drosophila melanogaster	36%	70%
Q9XGH7	Nicotiana tabacum	31%	100%
Q9XTT8	Caenorhabditis elegans	33%	100%
Q9XW79	Caenorhabditis elegans	33%	100%
Q9XZE5	Dictyostelium discoideum	31%	100%
Q9Y0B7	Dictyostelium discoideum	33%	100%
Q9ZSE4	Hevea brasiliensis	31%	100%
V5AUW3	Trypanosoma cruzi	30%	100%
V5B3V2	Trypanosoma cruzi	34%	100%
V5B5K9	Trypanosoma cruzi	30%	100%
V5B8G5	Trypanosoma cruzi	30%	100%
V5BBR3	Trypanosoma cruzi	50%	100%
V5BBS3	Trypanosoma cruzi	30%	68%
V5BGM0	Trypanosoma cruzi	28%	100%
V5BKU4	Trypanosoma cruzi	33%	100%
V5BQD7	Trypanosoma cruzi	27%	93%
V5D2G9	Trypanosoma cruzi	30%	100%
V5D5S2	Trypanosoma cruzi	30%	86%
V5DCW3	Trypanosoma cruzi	26%	100%
V5DIG8	Trypanosoma cruzi	29%	94%
V5DMS5	Trypanosoma cruzi	32%	100%