DEAD box RNA helicase, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DEAD box RNA helicase, putative

Species:

Leishmania donovani

UniProt:

A0A3S7XAN8_LEIDO

TriTrypDb:

LdBPK_361920.1 , LdCL_360024700 , LDHU3_36.2510

Length:

658

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3S7XAN8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XAN8

Function

Biological processes
Term	Name	Level	Count
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	10	1
GO:0000470	maturation of LSU-rRNA	9	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006364	rRNA processing	8	1
GO:0006396	RNA processing	6	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009987	cellular process	1	1
GO:0016070	RNA metabolic process	5	1
GO:0016072	rRNA metabolic process	7	1
GO:0034470	ncRNA processing	7	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0034660	ncRNA metabolic process	6	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0046483	heterocycle metabolic process	3	1
GO:0071704	organic substance metabolic process	2	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003723	RNA binding	4	11
GO:0003724	RNA helicase activity	3	11
GO:0003743	translation initiation factor activity	4	7
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0008135	translation factor activity, RNA binding	3	7
GO:0008186	ATP-dependent activity, acting on RNA	2	11
GO:0016787	hydrolase activity	2	8
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0045182	translation regulator activity	1	7
GO:0090079	translation regulator activity, nucleic acid binding	2	7
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140098	catalytic activity, acting on RNA	3	11
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	98	102	PF00656	0.615
CLV_NRD_NRD_1	31	33	PF00675	0.572
CLV_NRD_NRD_1	639	641	PF00675	0.596
CLV_NRD_NRD_1	89	91	PF00675	0.710
CLV_PCSK_KEX2_1	116	118	PF00082	0.723
CLV_PCSK_KEX2_1	29	31	PF00082	0.579
CLV_PCSK_KEX2_1	638	640	PF00082	0.564
CLV_PCSK_KEX2_1	649	651	PF00082	0.526
CLV_PCSK_KEX2_1	83	85	PF00082	0.679
CLV_PCSK_KEX2_1	87	89	PF00082	0.666
CLV_PCSK_PC1ET2_1	116	118	PF00082	0.778
CLV_PCSK_PC1ET2_1	29	31	PF00082	0.581
CLV_PCSK_PC1ET2_1	638	640	PF00082	0.569
CLV_PCSK_PC1ET2_1	649	651	PF00082	0.523
CLV_PCSK_PC1ET2_1	83	85	PF00082	0.680
CLV_PCSK_PC1ET2_1	87	89	PF00082	0.644
CLV_PCSK_PC7_1	84	90	PF00082	0.673
CLV_PCSK_SKI1_1	185	189	PF00082	0.509
CLV_PCSK_SKI1_1	202	206	PF00082	0.165
CLV_PCSK_SKI1_1	258	262	PF00082	0.209
CLV_PCSK_SKI1_1	312	316	PF00082	0.209
CLV_PCSK_SKI1_1	409	413	PF00082	0.215
CLV_PCSK_SKI1_1	451	455	PF00082	0.220
CLV_PCSK_SKI1_1	584	588	PF00082	0.276
CLV_PCSK_SKI1_1	635	639	PF00082	0.569
DEG_SCF_FBW7_1	187	192	PF00400	0.389
DEG_SPOP_SBC_1	135	139	PF00917	0.577
DOC_ANK_TNKS_1	116	123	PF00023	0.569
DOC_CYCLIN_RxL_1	243	253	PF00134	0.420
DOC_CYCLIN_RxL_1	309	320	PF00134	0.512
DOC_CYCLIN_yClb1_LxF_4	510	516	PF00134	0.310
DOC_MAPK_gen_1	408	419	PF00069	0.409
DOC_MAPK_gen_1	505	515	PF00069	0.473
DOC_MAPK_MEF2A_6	284	293	PF00069	0.420
DOC_MAPK_MEF2A_6	312	319	PF00069	0.409
DOC_MAPK_MEF2A_6	368	375	PF00069	0.323
DOC_MAPK_MEF2A_6	412	419	PF00069	0.409
DOC_MAPK_NFAT4_5	312	320	PF00069	0.409
DOC_PP1_RVXF_1	212	219	PF00149	0.409
DOC_PP1_RVXF_1	361	367	PF00149	0.322
DOC_PP1_RVXF_1	412	419	PF00149	0.409
DOC_PP2B_LxvP_1	476	479	PF13499	0.409
DOC_PP4_FxxP_1	218	221	PF00568	0.409
DOC_PP4_FxxP_1	487	490	PF00568	0.420
DOC_PP4_FxxP_1	515	518	PF00568	0.313
DOC_USP7_MATH_1	104	108	PF00917	0.648
DOC_USP7_MATH_1	128	132	PF00917	0.751
DOC_USP7_MATH_1	134	138	PF00917	0.702
DOC_USP7_MATH_1	189	193	PF00917	0.525
DOC_USP7_MATH_1	23	27	PF00917	0.642
DOC_USP7_UBL2_3	153	157	PF12436	0.574
DOC_USP7_UBL2_3	408	412	PF12436	0.420
DOC_USP7_UBL2_3	645	649	PF12436	0.632
DOC_USP7_UBL2_3	83	87	PF12436	0.766
DOC_WW_Pin1_4	124	129	PF00397	0.603
DOC_WW_Pin1_4	130	135	PF00397	0.552
DOC_WW_Pin1_4	136	141	PF00397	0.755
DOC_WW_Pin1_4	185	190	PF00397	0.506
DOC_WW_Pin1_4	292	297	PF00397	0.409
DOC_WW_Pin1_4	366	371	PF00397	0.464
DOC_WW_Pin1_4	69	74	PF00397	0.523
LIG_14-3-3_CanoR_1	345	349	PF00244	0.413
LIG_14-3-3_CanoR_1	363	367	PF00244	0.403
LIG_14-3-3_CanoR_1	4	10	PF00244	0.515
LIG_14-3-3_CanoR_1	422	428	PF00244	0.409
LIG_14-3-3_CanoR_1	451	456	PF00244	0.409
LIG_14-3-3_CanoR_1	564	571	PF00244	0.261
LIG_Actin_WH2_2	549	566	PF00022	0.261
LIG_BIR_II_1	1	5	PF00653	0.693
LIG_BRCT_BRCA1_1	265	269	PF00533	0.409
LIG_BRCT_BRCA1_1	423	427	PF00533	0.476
LIG_Clathr_ClatBox_1	316	320	PF01394	0.512
LIG_deltaCOP1_diTrp_1	480	487	PF00928	0.416
LIG_FHA_1	235	241	PF00498	0.428
LIG_FHA_1	243	249	PF00498	0.442
LIG_FHA_1	309	315	PF00498	0.413
LIG_FHA_1	353	359	PF00498	0.409
LIG_FHA_1	466	472	PF00498	0.409
LIG_FHA_1	537	543	PF00498	0.422
LIG_FHA_2	354	360	PF00498	0.409
LIG_LIR_Apic_2	215	221	PF02991	0.409
LIG_LIR_Gen_1	430	440	PF02991	0.424
LIG_LIR_Gen_1	452	462	PF02991	0.411
LIG_LIR_Gen_1	50	60	PF02991	0.592
LIG_LIR_Nem_3	163	168	PF02991	0.369
LIG_LIR_Nem_3	181	187	PF02991	0.364
LIG_LIR_Nem_3	430	435	PF02991	0.424
LIG_LIR_Nem_3	452	458	PF02991	0.411
LIG_LIR_Nem_3	50	56	PF02991	0.593
LIG_LIR_Nem_3	520	526	PF02991	0.308
LIG_NRBOX	255	261	PF00104	0.409
LIG_PCNA_yPIPBox_3	544	557	PF02747	0.389
LIG_Pex14_1	483	487	PF04695	0.409
LIG_Rb_pABgroove_1	522	530	PF01858	0.370
LIG_REV1ctd_RIR_1	416	426	PF16727	0.409
LIG_SH2_CRK	165	169	PF00017	0.379
LIG_SH2_CRK	404	408	PF00017	0.409
LIG_SH2_PTP2	434	437	PF00017	0.409
LIG_SH2_SRC	434	437	PF00017	0.409
LIG_SH2_SRC	528	531	PF00017	0.378
LIG_SH2_STAP1	53	57	PF00017	0.593
LIG_SH2_STAP1	538	542	PF00017	0.399
LIG_SH2_STAT5	391	394	PF00017	0.289
LIG_SH2_STAT5	434	437	PF00017	0.416
LIG_SH2_STAT5	496	499	PF00017	0.409
LIG_SH2_STAT5	526	529	PF00017	0.332
LIG_SH2_STAT5	538	541	PF00017	0.381
LIG_SH2_STAT5	562	565	PF00017	0.261
LIG_SH2_STAT5	574	577	PF00017	0.261
LIG_SH3_2	111	116	PF14604	0.576
LIG_SH3_2	490	495	PF14604	0.420
LIG_SH3_3	108	114	PF00018	0.641
LIG_SH3_3	137	143	PF00018	0.700
LIG_SH3_3	290	296	PF00018	0.512
LIG_SH3_3	487	493	PF00018	0.420
LIG_SUMO_SIM_anti_2	336	342	PF11976	0.409
LIG_SUMO_SIM_par_1	289	295	PF11976	0.434
LIG_SUMO_SIM_par_1	315	321	PF11976	0.409
LIG_TRAF2_1	518	521	PF00917	0.457
LIG_TRAF2_1	68	71	PF00917	0.701
LIG_TYR_ITIM	402	407	PF00017	0.409
LIG_UBA3_1	256	261	PF00899	0.409
LIG_UBA3_1	299	304	PF00899	0.409
LIG_UBA3_1	371	379	PF00899	0.358
LIG_UBA3_1	400	408	PF00899	0.436
MOD_CDC14_SPxK_1	295	298	PF00782	0.434
MOD_CDK_SPxK_1	292	298	PF00069	0.409
MOD_CK1_1	126	132	PF00069	0.795
MOD_CK1_1	234	240	PF00069	0.508
MOD_CK1_1	374	380	PF00069	0.546
MOD_CK1_1	421	427	PF00069	0.487
MOD_CK1_1	577	583	PF00069	0.271
MOD_CK2_1	173	179	PF00069	0.381
MOD_CK2_1	353	359	PF00069	0.419
MOD_CK2_1	621	627	PF00069	0.498
MOD_CK2_1	65	71	PF00069	0.716
MOD_GlcNHglycan	1	4	PF01048	0.669
MOD_GlcNHglycan	107	110	PF01048	0.773
MOD_GlcNHglycan	128	131	PF01048	0.738
MOD_GlcNHglycan	175	178	PF01048	0.461
MOD_GlcNHglycan	228	231	PF01048	0.305
MOD_GlcNHglycan	350	353	PF01048	0.209
MOD_GlcNHglycan	451	454	PF01048	0.225
MOD_GlcNHglycan	462	465	PF01048	0.199
MOD_GlcNHglycan	565	568	PF01048	0.269
MOD_GlcNHglycan	615	618	PF01048	0.480
MOD_GlcNHglycan	627	631	PF01048	0.473
MOD_GlcNHglycan	654	657	PF01048	0.533
MOD_GSK3_1	122	129	PF00069	0.655
MOD_GSK3_1	130	137	PF00069	0.586
MOD_GSK3_1	160	167	PF00069	0.502
MOD_GSK3_1	185	192	PF00069	0.354
MOD_GSK3_1	304	311	PF00069	0.444
MOD_GSK3_1	344	351	PF00069	0.413
MOD_GSK3_1	362	369	PF00069	0.482
MOD_GSK3_1	417	424	PF00069	0.488
MOD_GSK3_1	536	543	PF00069	0.400
MOD_GSK3_1	65	72	PF00069	0.731
MOD_GSK3_1	74	81	PF00069	0.714
MOD_LATS_1	302	308	PF00433	0.435
MOD_LATS_1	449	455	PF00433	0.409
MOD_N-GLC_1	234	239	PF02516	0.256
MOD_N-GLC_1	263	268	PF02516	0.209
MOD_N-GLC_1	652	657	PF02516	0.540
MOD_NEK2_1	155	160	PF00069	0.595
MOD_NEK2_1	263	268	PF00069	0.449
MOD_NEK2_1	348	353	PF00069	0.413
MOD_NEK2_1	418	423	PF00069	0.409
MOD_NEK2_1	540	545	PF00069	0.408
MOD_NEK2_1	556	561	PF00069	0.287
MOD_NEK2_1	563	568	PF00069	0.239
MOD_NEK2_1	576	581	PF00069	0.117
MOD_NEK2_1	611	616	PF00069	0.458
MOD_NEK2_2	362	367	PF00069	0.324
MOD_PIKK_1	146	152	PF00454	0.644
MOD_PIKK_1	350	356	PF00454	0.431
MOD_PIKK_1	611	617	PF00454	0.458
MOD_PKA_2	231	237	PF00069	0.489
MOD_PKA_2	344	350	PF00069	0.409
MOD_PKA_2	362	368	PF00069	0.329
MOD_PKA_2	421	427	PF00069	0.476
MOD_PKA_2	563	569	PF00069	0.261
MOD_PKA_2	631	637	PF00069	0.681
MOD_Plk_1	536	542	PF00069	0.377
MOD_Plk_1	626	632	PF00069	0.639
MOD_Plk_2-3	380	386	PF00069	0.415
MOD_Plk_2-3	65	71	PF00069	0.609
MOD_Plk_2-3	91	97	PF00069	0.751
MOD_Plk_4	265	271	PF00069	0.476
MOD_Plk_4	344	350	PF00069	0.444
MOD_Plk_4	451	457	PF00069	0.409
MOD_Plk_4	5	11	PF00069	0.508
MOD_ProDKin_1	124	130	PF00069	0.603
MOD_ProDKin_1	136	142	PF00069	0.751
MOD_ProDKin_1	185	191	PF00069	0.401
MOD_ProDKin_1	292	298	PF00069	0.409
MOD_ProDKin_1	366	372	PF00069	0.460
MOD_ProDKin_1	69	75	PF00069	0.522
MOD_SUMO_rev_2	158	168	PF00179	0.429
MOD_SUMO_rev_2	176	184	PF00179	0.351
MOD_SUMO_rev_2	203	210	PF00179	0.409
MOD_SUMO_rev_2	529	533	PF00179	0.460
MOD_SUMO_rev_2	61	69	PF00179	0.657
TRG_DiLeu_BaEn_1	336	341	PF01217	0.409
TRG_DiLeu_BaEn_1	397	402	PF01217	0.301
TRG_DiLeu_BaLyEn_6	295	300	PF01217	0.409
TRG_DiLeu_BaLyEn_6	396	401	PF01217	0.288
TRG_ENDOCYTIC_2	165	168	PF00928	0.359
TRG_ENDOCYTIC_2	404	407	PF00928	0.409
TRG_ENDOCYTIC_2	434	437	PF00928	0.416
TRG_ENDOCYTIC_2	455	458	PF00928	0.409
TRG_ENDOCYTIC_2	53	56	PF00928	0.593
TRG_ER_diArg_1	30	32	PF00400	0.629
TRG_ER_diArg_1	88	90	PF00400	0.675
TRG_NES_CRM1_1	593	605	PF08389	0.256
TRG_NLS_MonoCore_2	27	32	PF00514	0.584
TRG_NLS_MonoExtC_3	27	32	PF00514	0.609
TRG_NLS_MonoExtC_3	621	627	PF00514	0.479
TRG_NLS_MonoExtN_4	28	33	PF00514	0.586
TRG_NLS_MonoExtN_4	409	416	PF00514	0.409
TRG_Pf-PMV_PEXEL_1	202	207	PF00026	0.220
TRG_Pf-PMV_PEXEL_1	246	251	PF00026	0.209

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7J1	Leptomonas seymouri	37%	73%
A0A0N0P942	Leptomonas seymouri	28%	76%
A0A0N1I6K5	Leptomonas seymouri	80%	100%
A0A0N1IKV7	Leptomonas seymouri	31%	96%
A0A0N1PCZ7	Leptomonas seymouri	24%	100%
A0A0N1PDE7	Leptomonas seymouri	27%	100%
A0A0S4IWD0	Bodo saltans	72%	100%
A0A0S4JSZ9	Bodo saltans	30%	100%
A0A0S4KKU4	Bodo saltans	37%	95%
A0A1X0NJH3	Trypanosomatidae	25%	100%
A0A1X0NMD6	Trypanosomatidae	27%	80%
A0A1X0P5E1	Trypanosomatidae	33%	92%
A0A1X0P7S4	Trypanosomatidae	83%	100%
A0A3Q8IC45	Leishmania donovani	30%	100%
A0A3Q8ID91	Leishmania donovani	31%	100%
A0A3R7M1K3	Trypanosoma rangeli	35%	92%
A0A3R7NGQ1	Trypanosoma rangeli	71%	100%
A0A3S5H5G1	Leishmania donovani	31%	97%
A0A3S5H7C7	Leishmania donovani	24%	100%
A0A3S7X5R1	Leishmania donovani	33%	100%
A0A3S7XAT8	Leishmania donovani	33%	100%
A0A422NYB4	Trypanosoma rangeli	37%	78%
A1CB55	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	29%	87%
A1CIQ5	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	47%	100%
A1CKJ0	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	31%	100%
A1CL59	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	32%	100%
A1CTZ2	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	40%	80%
A1CW14	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	43%	100%
A1D699	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	32%	100%
A1DE84	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	30%	87%
A2Q9T6	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	53%	100%
A2QE29	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	31%	100%
A2RA55	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	31%	85%
A3GGE9	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	35%	86%
A3LNR6	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	52%	100%
A3LWH3	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	29%	90%
A3LX02	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	30%	100%
A4HGH8	Leishmania braziliensis	38%	73%
A4HGR1	Leishmania braziliensis	30%	100%
A4HKL3	Leishmania braziliensis	36%	85%
A4HP48	Leishmania braziliensis	87%	99%
A4HP49	Leishmania braziliensis	33%	100%
A4HT33	Leishmania infantum	35%	100%
A4HZF8	Leishmania infantum	29%	100%
A4I3T6	Leishmania infantum	31%	100%
A4I846	Leishmania infantum	34%	100%
A4IDF5	Leishmania infantum	100%	100%
A4IDF6	Leishmania infantum	33%	100%
A4R8B5	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	49%	100%
A4RGU2	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	38%	82%
A4RK80	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	30%	98%
A5DAR2	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	30%	88%
A5DGM4	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	32%	100%
A5DID7	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	49%	100%
A5DLF4	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	34%	87%
A5E2I8	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	30%	100%
A5E2Z9	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	53%	100%
A5E3K3	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	36%	85%
A6R918	Ajellomyces capsulatus (strain NAm1 / WU24)	31%	97%
A6RMZ2	Botryotinia fuckeliana (strain B05.10)	31%	100%
A6RSH5	Botryotinia fuckeliana (strain B05.10)	30%	75%
A6ZPU3	Saccharomyces cerevisiae (strain YJM789)	39%	85%
A6ZZY8	Saccharomyces cerevisiae (strain YJM789)	29%	89%
A7A237	Saccharomyces cerevisiae (strain YJM789)	32%	100%
A7ESL8	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	38%	81%
A7F2S3	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	30%	100%
A7F8V8	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	31%	75%
A7TJ71	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	38%	86%
A7TJS7	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	30%	100%
C9ZPV9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	80%
D0A331	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	72%	100%
D0A6Z3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
E9AH36	Leishmania infantum	24%	100%
E9AJG4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9AKB8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	96%
E9ASV6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
E9ASV7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9AVE1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9AWL4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9B028	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9B2I0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9B304	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
O60173	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	31%	93%
O74764	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	100%
P0CQ82	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	38%	77%
P0CQ83	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	38%	77%
P0CQ84	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	50%	100%
P0CQ85	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	50%	100%
P0CR02	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	30%	100%
P0CR03	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	30%	100%
P20448	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	39%	85%
P25808	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	32%	100%
P34640	Caenorhabditis elegans	32%	100%
P36120	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	29%	89%
P57453	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	33%	100%
Q03532	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	52%	100%
Q09916	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	51%	100%
Q0CF43	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	30%	86%
Q0CMM5	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	41%	82%
Q0CQF3	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	32%	100%
Q0CZS8	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	49%	100%
Q0D622	Oryza sativa subsp. japonica	39%	85%
Q0D8N0	Oryza sativa subsp. japonica	32%	100%
Q0DBS1	Oryza sativa subsp. japonica	46%	100%
Q0DBU5	Oryza sativa subsp. japonica	32%	100%
Q0DLB9	Oryza sativa subsp. japonica	32%	100%
Q0U8V9	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	32%	100%
Q0UMB9	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	39%	82%
Q0UP45	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	32%	100%
Q0UR48	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	51%	100%
Q13206	Homo sapiens	39%	75%
Q1E1R7	Coccidioides immitis (strain RS)	32%	100%
Q1E2B2	Coccidioides immitis (strain RS)	31%	78%
Q1E9T9	Coccidioides immitis (strain RS)	29%	86%
Q1EA54	Coccidioides immitis (strain RS)	52%	100%
Q1EB31	Coccidioides immitis (strain RS)	38%	82%
Q2GMX1	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	51%	100%
Q2GV49	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	33%	100%
Q2GZU7	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	32%	82%
Q2H2J1	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	40%	80%
Q2NL08	Bos taurus	39%	100%
Q2UBZ5	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	32%	100%
Q2UE66	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	30%	87%
Q2UST1	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	30%	100%
Q2UUN6	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	46%	100%
Q4HVW2	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	31%	100%
Q4HZ68	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	30%	88%
Q4IAS1	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	36%	83%
Q4IEK8	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	52%	100%
Q4P5U4	Ustilago maydis (strain 521 / FGSC 9021)	36%	72%
Q4PEX7	Ustilago maydis (strain 521 / FGSC 9021)	30%	100%
Q4Q1N9	Leishmania major	33%	100%
Q4Q1P0	Leishmania major	95%	100%
Q4Q552	Leishmania major	34%	85%
Q4Q858	Leishmania major	32%	100%
Q4QC38	Leishmania major	30%	100%
Q4QJI9	Leishmania major	31%	98%
Q4WM60	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	38%	84%
Q4WQM4	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	44%	100%
Q4WV71	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	31%	87%
Q4WYJ7	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	32%	100%
Q54EC2	Dictyostelium discoideum	33%	99%
Q54Q94	Dictyostelium discoideum	38%	75%
Q54S03	Dictyostelium discoideum	51%	100%
Q59N29	Candida albicans (strain SC5314 / ATCC MYA-2876)	30%	100%
Q59S50	Candida albicans (strain SC5314 / ATCC MYA-2876)	28%	91%
Q5AF95	Candida albicans (strain SC5314 / ATCC MYA-2876)	37%	86%
Q5AK59	Candida albicans (strain SC5314 / ATCC MYA-2876)	53%	100%
Q5APM7	Candida albicans (strain SC5314 / ATCC MYA-2876)	32%	99%
Q5B8F4	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	32%	100%
Q5BBY1	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	53%	100%
Q5BFU1	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	38%	81%
Q5BGX6	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	31%	85%
Q5VQL1	Oryza sativa subsp. japonica	30%	93%
Q5ZJF6	Gallus gallus	38%	75%
Q5ZLN8	Gallus gallus	39%	100%
Q61R02	Caenorhabditis briggsae	31%	100%
Q65N62	Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46)	31%	100%
Q6AZV7	Xenopus laevis	38%	100%
Q6BH93	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	45%	100%
Q6BKH3	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	28%	82%
Q6BSM3	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	31%	100%
Q6BXG0	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	38%	86%
Q6C193	Yarrowia lipolytica (strain CLIB 122 / E 150)	32%	100%
Q6C7D2	Yarrowia lipolytica (strain CLIB 122 / E 150)	52%	100%
Q6C835	Yarrowia lipolytica (strain CLIB 122 / E 150)	31%	82%
Q6CGD1	Yarrowia lipolytica (strain CLIB 122 / E 150)	38%	89%
Q6CK32	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	28%	89%
Q6CN92	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	33%	100%
Q6CRF4	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	38%	85%
Q6CXB7	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	52%	100%
Q6FIL3	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	53%	100%
Q6FKS8	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	31%	100%
Q6FPT7	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	37%	86%
Q6K7R9	Oryza sativa subsp. japonica	30%	81%
Q6NZQ2	Mus musculus	31%	96%
Q6ZPL9	Mus musculus	39%	100%
Q74Z73	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	51%	100%
Q750F8	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	32%	100%
Q754J2	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	29%	93%
Q75C76	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	38%	86%
Q7RYZ7	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	33%	100%
Q7RZ35	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	39%	80%
Q7S2N9	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	48%	100%
Q7S873	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	30%	81%
Q7XJN0	Arabidopsis thaliana	32%	100%
Q80Y44	Mus musculus	40%	75%
Q84T03	Oryza sativa subsp. japonica	48%	100%
Q86B47	Drosophila melanogaster	31%	67%
Q873H9	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	32%	100%
Q8GXD6	Arabidopsis thaliana	34%	100%
Q8H136	Arabidopsis thaliana	32%	100%
Q8JHJ2	Danio rerio	38%	100%
Q8K363	Mus musculus	54%	100%
Q8NHQ9	Homo sapiens	39%	100%
Q8SR49	Encephalitozoon cuniculi (strain GB-M1)	32%	100%
Q94C75	Arabidopsis thaliana	32%	100%
Q9FFQ1	Arabidopsis thaliana	32%	92%
Q9FLB0	Arabidopsis thaliana	32%	100%
Q9FNM7	Arabidopsis thaliana	33%	77%
Q9H8H2	Homo sapiens	33%	77%
Q9LIH9	Arabidopsis thaliana	46%	100%
Q9LYJ9	Arabidopsis thaliana	30%	100%
Q9NVP1	Homo sapiens	53%	98%
Q9SB89	Arabidopsis thaliana	46%	100%
Q9VD51	Drosophila melanogaster	54%	97%
Q9VHU1	Drosophila melanogaster	34%	100%
Q9Y7C4	Candida albicans (strain SC5314 / ATCC MYA-2876)	30%	100%
V5DAZ9	Trypanosoma cruzi	37%	69%
V5DCA1	Trypanosoma cruzi	36%	92%
V5DKV2	Trypanosoma cruzi	69%	100%