LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7XAI1_LEIDO
TriTrypDb:
LdBPK_361280.1 * , LdCL_360017900 , LDHU3_36.1620
Length:
496

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7XAI1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XAI1

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 192 196 PF00656 0.637
CLV_C14_Caspase3-7 343 347 PF00656 0.593
CLV_C14_Caspase3-7 360 364 PF00656 0.654
CLV_NRD_NRD_1 388 390 PF00675 0.554
CLV_NRD_NRD_1 451 453 PF00675 0.573
CLV_PCSK_KEX2_1 388 390 PF00082 0.558
CLV_PCSK_SKI1_1 333 337 PF00082 0.620
DEG_Nend_UBRbox_2 1 3 PF02207 0.656
DEG_SPOP_SBC_1 286 290 PF00917 0.638
DOC_CKS1_1 233 238 PF01111 0.640
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Homologs

ProteinTaxonomySequence identityCoverage
A4HNY2 Leishmania braziliensis 53% 100%
A4ICL2 Leishmania infantum 99% 100%
E9ASP2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 78% 100%
Q4Q1V4 Leishmania major 81% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS