Guanylate cyclase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Guanylate cyclase

Gene product:

mitogen-activated protein kinase-like protein

Species:

Leishmania donovani

UniProt:

A0A3S7XAH3_LEIDO

TriTrypDb:

LdBPK_360970.1 , LdCL_360014700 , LDHU3_36.1290

Length:

1563

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6

Expansion

Sequence features

A0A3S7XAH3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	7
GO:0006163	purine nucleotide metabolic process	5	7
GO:0006164	purine nucleotide biosynthetic process	6	7
GO:0006171	cAMP biosynthetic process	8	7
GO:0006182	cGMP biosynthetic process	8	7
GO:0006468	protein phosphorylation	5	7
GO:0006725	cellular aromatic compound metabolic process	3	7
GO:0006753	nucleoside phosphate metabolic process	4	7
GO:0006793	phosphorus metabolic process	3	7
GO:0006796	phosphate-containing compound metabolic process	4	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0008152	metabolic process	1	7
GO:0009058	biosynthetic process	2	7
GO:0009117	nucleotide metabolic process	5	7
GO:0009150	purine ribonucleotide metabolic process	6	7
GO:0009152	purine ribonucleotide biosynthetic process	7	7
GO:0009165	nucleotide biosynthetic process	6	7
GO:0009187	cyclic nucleotide metabolic process	6	7
GO:0009190	cyclic nucleotide biosynthetic process	7	7
GO:0009259	ribonucleotide metabolic process	5	7
GO:0009260	ribonucleotide biosynthetic process	6	7
GO:0009987	cellular process	1	7
GO:0016310	phosphorylation	5	7
GO:0018130	heterocycle biosynthetic process	4	7
GO:0019438	aromatic compound biosynthetic process	4	7
GO:0019538	protein metabolic process	3	7
GO:0019637	organophosphate metabolic process	3	7
GO:0019693	ribose phosphate metabolic process	4	7
GO:0034641	cellular nitrogen compound metabolic process	3	7
GO:0034654	nucleobase-containing compound biosynthetic process	4	7
GO:0036211	protein modification process	4	7
GO:0043170	macromolecule metabolic process	3	7
GO:0043412	macromolecule modification	4	7
GO:0044237	cellular metabolic process	2	7
GO:0044238	primary metabolic process	2	7
GO:0044249	cellular biosynthetic process	3	7
GO:0044271	cellular nitrogen compound biosynthetic process	4	7
GO:0044281	small molecule metabolic process	2	7
GO:0046058	cAMP metabolic process	7	7
GO:0046068	cGMP metabolic process	7	7
GO:0046390	ribose phosphate biosynthetic process	5	7
GO:0046483	heterocycle metabolic process	3	7
GO:0052652	cyclic purine nucleotide metabolic process	6	7
GO:0055086	nucleobase-containing small molecule metabolic process	3	7
GO:0071704	organic substance metabolic process	2	7
GO:0072521	purine-containing compound metabolic process	4	7
GO:0072522	purine-containing compound biosynthetic process	5	7
GO:0090407	organophosphate biosynthetic process	4	7
GO:1901135	carbohydrate derivative metabolic process	3	7
GO:1901137	carbohydrate derivative biosynthetic process	4	7
GO:1901293	nucleoside phosphate biosynthetic process	5	7
GO:1901360	organic cyclic compound metabolic process	3	7
GO:1901362	organic cyclic compound biosynthetic process	4	7
GO:1901564	organonitrogen compound metabolic process	3	7
GO:1901566	organonitrogen compound biosynthetic process	4	7
GO:1901576	organic substance biosynthetic process	3	7
GO:0007165	signal transduction	2	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0065007	biological regulation	1	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	7
GO:0003824	catalytic activity	1	7
GO:0004672	protein kinase activity	3	7
GO:0005488	binding	1	7
GO:0005524	ATP binding	5	7
GO:0016301	kinase activity	4	7
GO:0016740	transferase activity	2	7
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	7
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	7
GO:0017076	purine nucleotide binding	4	7
GO:0030554	adenyl nucleotide binding	5	7
GO:0032553	ribonucleotide binding	3	7
GO:0032555	purine ribonucleotide binding	4	7
GO:0032559	adenyl ribonucleotide binding	5	7
GO:0035639	purine ribonucleoside triphosphate binding	4	7
GO:0036094	small molecule binding	2	7
GO:0043167	ion binding	2	7
GO:0043168	anion binding	3	7
GO:0097159	organic cyclic compound binding	2	7
GO:0097367	carbohydrate derivative binding	2	7
GO:0140096	catalytic activity, acting on a protein	2	7
GO:1901265	nucleoside phosphate binding	3	7
GO:1901363	heterocyclic compound binding	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1143	1147	PF00656	0.782
CLV_C14_Caspase3-7	1448	1452	PF00656	0.619
CLV_C14_Caspase3-7	196	200	PF00656	0.546
CLV_C14_Caspase3-7	777	781	PF00656	0.623
CLV_MEL_PAP_1	545	551	PF00089	0.525
CLV_MEL_PAP_1	560	566	PF00089	0.491
CLV_NRD_NRD_1	102	104	PF00675	0.445
CLV_NRD_NRD_1	1089	1091	PF00675	0.455
CLV_NRD_NRD_1	1209	1211	PF00675	0.450
CLV_NRD_NRD_1	1398	1400	PF00675	0.346
CLV_NRD_NRD_1	1551	1553	PF00675	0.394
CLV_NRD_NRD_1	172	174	PF00675	0.504
CLV_NRD_NRD_1	24	26	PF00675	0.422
CLV_NRD_NRD_1	290	292	PF00675	0.516
CLV_NRD_NRD_1	432	434	PF00675	0.585
CLV_NRD_NRD_1	489	491	PF00675	0.461
CLV_NRD_NRD_1	63	65	PF00675	0.492
CLV_NRD_NRD_1	67	69	PF00675	0.471
CLV_NRD_NRD_1	962	964	PF00675	0.508
CLV_NRD_NRD_1	971	973	PF00675	0.402
CLV_NRD_NRD_1	980	982	PF00675	0.282
CLV_NRD_NRD_1	998	1000	PF00675	0.255
CLV_PCSK_KEX2_1	1027	1029	PF00082	0.513
CLV_PCSK_KEX2_1	1089	1091	PF00082	0.455
CLV_PCSK_KEX2_1	1209	1211	PF00082	0.467
CLV_PCSK_KEX2_1	1551	1553	PF00082	0.394
CLV_PCSK_KEX2_1	171	173	PF00082	0.508
CLV_PCSK_KEX2_1	432	434	PF00082	0.600
CLV_PCSK_KEX2_1	488	490	PF00082	0.458
CLV_PCSK_KEX2_1	534	536	PF00082	0.660
CLV_PCSK_KEX2_1	638	640	PF00082	0.456
CLV_PCSK_KEX2_1	67	69	PF00082	0.474
CLV_PCSK_KEX2_1	962	964	PF00082	0.508
CLV_PCSK_KEX2_1	971	973	PF00082	0.402
CLV_PCSK_KEX2_1	980	982	PF00082	0.456
CLV_PCSK_KEX2_1	998	1000	PF00082	0.266
CLV_PCSK_PC1ET2_1	1027	1029	PF00082	0.512
CLV_PCSK_PC1ET2_1	534	536	PF00082	0.604
CLV_PCSK_PC1ET2_1	638	640	PF00082	0.456
CLV_PCSK_SKI1_1	109	113	PF00082	0.373
CLV_PCSK_SKI1_1	1151	1155	PF00082	0.562
CLV_PCSK_SKI1_1	1447	1451	PF00082	0.266
CLV_PCSK_SKI1_1	256	260	PF00082	0.532
CLV_PCSK_SKI1_1	278	282	PF00082	0.591
CLV_PCSK_SKI1_1	531	535	PF00082	0.613
CLV_PCSK_SKI1_1	570	574	PF00082	0.486
CLV_PCSK_SKI1_1	641	645	PF00082	0.428
CLV_PCSK_SKI1_1	654	658	PF00082	0.373
CLV_PCSK_SKI1_1	677	681	PF00082	0.368
CLV_PCSK_SKI1_1	943	947	PF00082	0.340
DEG_APCC_DBOX_1	1088	1096	PF00400	0.725
DEG_APCC_DBOX_1	277	285	PF00400	0.391
DEG_MDM2_SWIB_1	307	315	PF02201	0.349
DEG_SCF_FBW7_1	1455	1462	PF00400	0.619
DEG_SPOP_SBC_1	1180	1184	PF00917	0.582
DEG_SPOP_SBC_1	2	6	PF00917	0.693
DOC_CYCLIN_yCln2_LP_2	1174	1177	PF00134	0.656
DOC_CYCLIN_yCln2_LP_2	50	53	PF00134	0.552
DOC_MAPK_gen_1	1399	1407	PF00069	0.546
DOC_MAPK_gen_1	208	217	PF00069	0.629
DOC_MAPK_gen_1	291	298	PF00069	0.354
DOC_MAPK_gen_1	463	472	PF00069	0.413
DOC_MAPK_gen_1	758	766	PF00069	0.544
DOC_MAPK_gen_1	837	845	PF00069	0.509
DOC_MAPK_HePTP_8	209	221	PF00069	0.619
DOC_MAPK_MEF2A_6	210	219	PF00069	0.619
DOC_MAPK_MEF2A_6	43	51	PF00069	0.646
DOC_MAPK_MEF2A_6	587	595	PF00069	0.363
DOC_MAPK_MEF2A_6	760	768	PF00069	0.581
DOC_MAPK_MEF2A_6	839	847	PF00069	0.512
DOC_PP1_RVXF_1	999	1005	PF00149	0.607
DOC_PP2B_LxvP_1	1174	1177	PF13499	0.644
DOC_PP2B_LxvP_1	303	306	PF13499	0.422
DOC_PP2B_LxvP_1	50	53	PF13499	0.608
DOC_PP2B_LxvP_1	697	700	PF13499	0.519
DOC_PP2B_LxvP_1	90	93	PF13499	0.567
DOC_PP4_FxxP_1	1461	1464	PF00568	0.546
DOC_PP4_FxxP_1	32	35	PF00568	0.714
DOC_PP4_FxxP_1	816	819	PF00568	0.575
DOC_USP7_MATH_1	102	106	PF00917	0.634
DOC_USP7_MATH_1	1034	1038	PF00917	0.650
DOC_USP7_MATH_1	1094	1098	PF00917	0.669
DOC_USP7_MATH_1	1123	1127	PF00917	0.764
DOC_USP7_MATH_1	1140	1144	PF00917	0.750
DOC_USP7_MATH_1	122	126	PF00917	0.527
DOC_USP7_MATH_1	1256	1260	PF00917	0.681
DOC_USP7_MATH_1	2	6	PF00917	0.721
DOC_USP7_MATH_1	775	779	PF00917	0.643
DOC_USP7_UBL2_3	100	104	PF12436	0.559
DOC_USP7_UBL2_3	459	463	PF12436	0.307
DOC_USP7_UBL2_3	943	947	PF12436	0.571
DOC_WW_Pin1_4	1119	1124	PF00397	0.814
DOC_WW_Pin1_4	1181	1186	PF00397	0.718
DOC_WW_Pin1_4	1220	1225	PF00397	0.716
DOC_WW_Pin1_4	141	146	PF00397	0.727
DOC_WW_Pin1_4	1455	1460	PF00397	0.619
DOC_WW_Pin1_4	483	488	PF00397	0.469
DOC_WW_Pin1_4	491	496	PF00397	0.429
DOC_WW_Pin1_4	52	57	PF00397	0.545
DOC_WW_Pin1_4	933	938	PF00397	0.572
DOC_WW_Pin1_4	971	976	PF00397	0.583
LIG_14-3-3_CanoR_1	103	112	PF00244	0.712
LIG_14-3-3_CanoR_1	1031	1037	PF00244	0.652
LIG_14-3-3_CanoR_1	1293	1298	PF00244	0.599
LIG_14-3-3_CanoR_1	1447	1455	PF00244	0.572
LIG_14-3-3_CanoR_1	1460	1464	PF00244	0.531
LIG_14-3-3_CanoR_1	1513	1517	PF00244	0.619
LIG_14-3-3_CanoR_1	203	207	PF00244	0.611
LIG_14-3-3_CanoR_1	278	284	PF00244	0.384
LIG_14-3-3_CanoR_1	285	289	PF00244	0.314
LIG_14-3-3_CanoR_1	639	644	PF00244	0.684
LIG_14-3-3_CanoR_1	654	662	PF00244	0.526
LIG_14-3-3_CanoR_1	67	75	PF00244	0.740
LIG_14-3-3_CanoR_1	758	766	PF00244	0.572
LIG_APCC_ABBA_1	360	365	PF00400	0.352
LIG_APCC_ABBA_1	553	558	PF00400	0.300
LIG_APCC_ABBA_1	909	914	PF00400	0.556
LIG_BIR_III_4	445	449	PF00653	0.269
LIG_BRCT_BRCA1_1	1096	1100	PF00533	0.647
LIG_BRCT_BRCA1_1	1182	1186	PF00533	0.617
LIG_BRCT_BRCA1_1	446	450	PF00533	0.405
LIG_BRCT_BRCA1_1	468	472	PF00533	0.377
LIG_BRCT_BRCA1_1	688	692	PF00533	0.631
LIG_deltaCOP1_diTrp_1	309	316	PF00928	0.367
LIG_deltaCOP1_diTrp_1	451	457	PF00928	0.440
LIG_deltaCOP1_diTrp_1	747	756	PF00928	0.596
LIG_EH1_1	921	929	PF00400	0.568
LIG_eIF4E_1	1401	1407	PF01652	0.546
LIG_FHA_1	1036	1042	PF00498	0.666
LIG_FHA_1	1196	1202	PF00498	0.746
LIG_FHA_1	13	19	PF00498	0.728
LIG_FHA_1	1303	1309	PF00498	0.626
LIG_FHA_1	1322	1328	PF00498	0.404
LIG_FHA_1	1432	1438	PF00498	0.546
LIG_FHA_1	1448	1454	PF00498	0.546
LIG_FHA_1	300	306	PF00498	0.379
LIG_FHA_1	321	327	PF00498	0.366
LIG_FHA_1	426	432	PF00498	0.344
LIG_FHA_1	520	526	PF00498	0.353
LIG_FHA_1	544	550	PF00498	0.364
LIG_FHA_1	569	575	PF00498	0.411
LIG_FHA_1	760	766	PF00498	0.558
LIG_FHA_1	890	896	PF00498	0.585
LIG_FHA_2	1496	1502	PF00498	0.563
LIG_FHA_2	1552	1558	PF00498	0.546
LIG_FHA_2	403	409	PF00498	0.414
LIG_FHA_2	6	12	PF00498	0.679
LIG_FHA_2	655	661	PF00498	0.566
LIG_FHA_2	855	861	PF00498	0.604
LIG_GSK3_LRP6_1	52	57	PF00069	0.545
LIG_LIR_Apic_2	1287	1291	PF02991	0.574
LIG_LIR_Apic_2	1458	1464	PF02991	0.546
LIG_LIR_Apic_2	29	35	PF02991	0.699
LIG_LIR_Apic_2	814	819	PF02991	0.577
LIG_LIR_Apic_2	97	102	PF02991	0.641
LIG_LIR_Gen_1	1316	1323	PF02991	0.619
LIG_LIR_Gen_1	325	335	PF02991	0.453
LIG_LIR_Gen_1	451	461	PF02991	0.432
LIG_LIR_Gen_1	551	560	PF02991	0.350
LIG_LIR_Gen_1	588	598	PF02991	0.363
LIG_LIR_Gen_1	665	673	PF02991	0.559
LIG_LIR_Gen_1	804	812	PF02991	0.540
LIG_LIR_LC3C_4	761	766	PF02991	0.647
LIG_LIR_Nem_3	1103	1109	PF02991	0.588
LIG_LIR_Nem_3	1313	1317	PF02991	0.546
LIG_LIR_Nem_3	1368	1374	PF02991	0.546
LIG_LIR_Nem_3	302	307	PF02991	0.362
LIG_LIR_Nem_3	408	412	PF02991	0.337
LIG_LIR_Nem_3	451	457	PF02991	0.425
LIG_LIR_Nem_3	551	555	PF02991	0.348
LIG_LIR_Nem_3	558	562	PF02991	0.360
LIG_LIR_Nem_3	588	593	PF02991	0.407
LIG_LIR_Nem_3	665	669	PF02991	0.558
LIG_LIR_Nem_3	747	752	PF02991	0.606
LIG_LIR_Nem_3	804	808	PF02991	0.527
LIG_LIR_Nem_3	849	854	PF02991	0.571
LIG_LIR_Nem_3	944	949	PF02991	0.573
LIG_MLH1_MIPbox_1	446	450	PF16413	0.366
LIG_MYND_1	56	60	PF01753	0.559
LIG_NRBOX	1557	1563	PF00104	0.717
LIG_NRBOX	216	222	PF00104	0.513
LIG_PCNA_yPIPBox_3	432	441	PF02747	0.431
LIG_Pex14_1	453	457	PF04695	0.372
LIG_Pex14_2	307	311	PF04695	0.348
LIG_Pex14_2	449	453	PF04695	0.337
LIG_Pex14_2	812	816	PF04695	0.578
LIG_PTB_Apo_2	236	243	PF02174	0.378
LIG_PTB_Apo_2	298	305	PF02174	0.314
LIG_PTB_Apo_2	660	667	PF02174	0.614
LIG_PTB_Phospho_1	236	242	PF10480	0.377
LIG_PTB_Phospho_1	298	304	PF10480	0.315
LIG_Rb_LxCxE_1	55	72	PF01857	0.558
LIG_REV1ctd_RIR_1	447	456	PF16727	0.375
LIG_SH2_CRK	1288	1292	PF00017	0.601
LIG_SH2_CRK	242	246	PF00017	0.370
LIG_SH2_CRK	391	395	PF00017	0.330
LIG_SH2_CRK	577	581	PF00017	0.365
LIG_SH2_CRK	851	855	PF00017	0.575
LIG_SH2_CRK	932	936	PF00017	0.589
LIG_SH2_NCK_1	1497	1501	PF00017	0.619
LIG_SH2_PTP2	1318	1321	PF00017	0.536
LIG_SH2_PTP2	393	396	PF00017	0.302
LIG_SH2_PTP2	552	555	PF00017	0.271
LIG_SH2_SRC	250	253	PF00017	0.373
LIG_SH2_STAP1	1361	1365	PF00017	0.546
LIG_SH2_STAP1	1401	1405	PF00017	0.546
LIG_SH2_STAT3	1411	1414	PF00017	0.546
LIG_SH2_STAT3	997	1000	PF00017	0.590
LIG_SH2_STAT5	1318	1321	PF00017	0.546
LIG_SH2_STAT5	1377	1380	PF00017	0.555
LIG_SH2_STAT5	1411	1414	PF00017	0.546
LIG_SH2_STAT5	1497	1500	PF00017	0.573
LIG_SH2_STAT5	242	245	PF00017	0.427
LIG_SH2_STAT5	250	253	PF00017	0.315
LIG_SH2_STAT5	304	307	PF00017	0.349
LIG_SH2_STAT5	327	330	PF00017	0.461
LIG_SH2_STAT5	393	396	PF00017	0.357
LIG_SH2_STAT5	411	414	PF00017	0.365
LIG_SH2_STAT5	552	555	PF00017	0.396
LIG_SH2_STAT5	853	856	PF00017	0.596
LIG_SH2_STAT5	884	887	PF00017	0.541
LIG_SH3_1	972	978	PF00018	0.638
LIG_SH3_2	975	980	PF14604	0.707
LIG_SH3_3	1182	1188	PF00018	0.700
LIG_SH3_3	133	139	PF00018	0.617
LIG_SH3_3	1523	1529	PF00018	0.546
LIG_SH3_3	24	30	PF00018	0.672
LIG_SH3_3	336	342	PF00018	0.370
LIG_SH3_3	346	352	PF00018	0.295
LIG_SH3_3	4	10	PF00018	0.813
LIG_SH3_3	46	52	PF00018	0.707
LIG_SH3_3	489	495	PF00018	0.346
LIG_SH3_3	675	681	PF00018	0.567
LIG_SH3_3	693	699	PF00018	0.606
LIG_SH3_3	72	78	PF00018	0.700
LIG_SH3_3	722	728	PF00018	0.681
LIG_SH3_3	739	745	PF00018	0.511
LIG_SH3_3	931	937	PF00018	0.588
LIG_SH3_3	972	978	PF00018	0.708
LIG_SUMO_SIM_anti_2	1556	1563	PF11976	0.712
LIG_SUMO_SIM_anti_2	261	267	PF11976	0.389
LIG_SUMO_SIM_anti_2	294	300	PF11976	0.311
LIG_SUMO_SIM_anti_2	439	445	PF11976	0.423
LIG_SUMO_SIM_anti_2	761	767	PF11976	0.648
LIG_SUMO_SIM_par_1	1151	1157	PF11976	0.722
LIG_SUMO_SIM_par_1	154	159	PF11976	0.679
LIG_SUMO_SIM_par_1	1556	1563	PF11976	0.712
LIG_SUMO_SIM_par_1	439	445	PF11976	0.422
LIG_SUMO_SIM_par_1	620	626	PF11976	0.553
LIG_SUMO_SIM_par_1	761	767	PF11976	0.576
LIG_SUMO_SIM_par_1	798	804	PF11976	0.559
LIG_TRAF2_1	1554	1557	PF00917	0.546
LIG_WRC_WIRS_1	1477	1482	PF05994	0.411
LIG_WRC_WIRS_1	280	285	PF05994	0.479
LIG_WRC_WIRS_1	520	525	PF05994	0.472
LIG_WRC_WIRS_1	559	564	PF05994	0.405
LIG_WRC_WIRS_1	809	814	PF05994	0.443
LIG_WRPW_2	676	679	PF00400	0.418
LIG_WW_3	76	80	PF00397	0.524
MOD_CDK_SPK_2	1455	1460	PF00069	0.513
MOD_CDK_SPK_2	483	488	PF00069	0.293
MOD_CDK_SPxK_1	483	489	PF00069	0.539
MOD_CDK_SPxxK_3	483	490	PF00069	0.292
MOD_CK1_1	1023	1029	PF00069	0.598
MOD_CK1_1	1037	1043	PF00069	0.369
MOD_CK1_1	1083	1089	PF00069	0.604
MOD_CK1_1	1098	1104	PF00069	0.343
MOD_CK1_1	1122	1128	PF00069	0.828
MOD_CK1_1	1203	1209	PF00069	0.604
MOD_CK1_1	1254	1260	PF00069	0.677
MOD_CK1_1	1431	1437	PF00069	0.411
MOD_CK1_1	1515	1521	PF00069	0.513
MOD_CK1_1	175	181	PF00069	0.618
MOD_CK1_1	3	9	PF00069	0.789
MOD_CK1_1	322	328	PF00069	0.430
MOD_CK1_1	42	48	PF00069	0.574
MOD_CK1_1	494	500	PF00069	0.395
MOD_CK1_1	626	632	PF00069	0.571
MOD_CK1_1	683	689	PF00069	0.447
MOD_CK1_1	811	817	PF00069	0.453
MOD_CK1_1	877	883	PF00069	0.527
MOD_CK2_1	1067	1073	PF00069	0.560
MOD_CK2_1	1310	1316	PF00069	0.513
MOD_CK2_1	1459	1465	PF00069	0.411
MOD_CK2_1	1551	1557	PF00069	0.411
MOD_CK2_1	188	194	PF00069	0.569
MOD_CK2_1	5	11	PF00069	0.640
MOD_CK2_1	854	860	PF00069	0.490
MOD_CMANNOS	311	314	PF00535	0.518
MOD_Cter_Amidation	289	292	PF01082	0.331
MOD_GlcNHglycan	105	108	PF01048	0.552
MOD_GlcNHglycan	1061	1064	PF01048	0.547
MOD_GlcNHglycan	1141	1145	PF01048	0.765
MOD_GlcNHglycan	1211	1214	PF01048	0.714
MOD_GlcNHglycan	1237	1240	PF01048	0.603
MOD_GlcNHglycan	1244	1247	PF01048	0.655
MOD_GlcNHglycan	1258	1261	PF01048	0.672
MOD_GlcNHglycan	1268	1271	PF01048	0.590
MOD_GlcNHglycan	1461	1464	PF01048	0.411
MOD_GlcNHglycan	1538	1541	PF01048	0.513
MOD_GlcNHglycan	194	199	PF01048	0.436
MOD_GlcNHglycan	252	255	PF01048	0.461
MOD_GlcNHglycan	381	384	PF01048	0.327
MOD_GlcNHglycan	445	449	PF01048	0.387
MOD_GlcNHglycan	657	660	PF01048	0.539
MOD_GlcNHglycan	711	714	PF01048	0.436
MOD_GlcNHglycan	848	851	PF01048	0.438
MOD_GlcNHglycan	994	997	PF01048	0.466
MOD_GSK3_1	1	8	PF00069	0.616
MOD_GSK3_1	1094	1101	PF00069	0.531
MOD_GSK3_1	1107	1114	PF00069	0.454
MOD_GSK3_1	1119	1126	PF00069	0.748
MOD_GSK3_1	1140	1147	PF00069	0.757
MOD_GSK3_1	1176	1183	PF00069	0.570
MOD_GSK3_1	1195	1202	PF00069	0.593
MOD_GSK3_1	1205	1212	PF00069	0.608
MOD_GSK3_1	1226	1233	PF00069	0.505
MOD_GSK3_1	1242	1249	PF00069	0.543
MOD_GSK3_1	1251	1258	PF00069	0.663
MOD_GSK3_1	1319	1326	PF00069	0.509
MOD_GSK3_1	1427	1434	PF00069	0.485
MOD_GSK3_1	1441	1448	PF00069	0.309
MOD_GSK3_1	1451	1458	PF00069	0.411
MOD_GSK3_1	1476	1483	PF00069	0.411
MOD_GSK3_1	279	286	PF00069	0.516
MOD_GSK3_1	310	317	PF00069	0.434
MOD_GSK3_1	322	329	PF00069	0.416
MOD_GSK3_1	340	347	PF00069	0.242
MOD_GSK3_1	623	630	PF00069	0.459
MOD_GSK3_1	686	693	PF00069	0.523
MOD_GSK3_1	734	741	PF00069	0.557
MOD_GSK3_1	885	892	PF00069	0.418
MOD_N-GLC_1	1020	1025	PF02516	0.618
MOD_N-GLC_1	259	264	PF02516	0.443
MOD_N-GLC_1	379	384	PF02516	0.421
MOD_NEK2_1	1032	1037	PF00069	0.682
MOD_NEK2_1	1085	1090	PF00069	0.607
MOD_NEK2_1	1178	1183	PF00069	0.466
MOD_NEK2_1	1205	1210	PF00069	0.625
MOD_NEK2_1	1255	1260	PF00069	0.563
MOD_NEK2_1	1284	1289	PF00069	0.575
MOD_NEK2_1	1302	1307	PF00069	0.431
MOD_NEK2_1	1445	1450	PF00069	0.411
MOD_NEK2_1	1480	1485	PF00069	0.411
MOD_NEK2_1	167	172	PF00069	0.607
MOD_NEK2_1	259	264	PF00069	0.394
MOD_NEK2_1	283	288	PF00069	0.555
MOD_NEK2_1	315	320	PF00069	0.433
MOD_NEK2_1	344	349	PF00069	0.410
MOD_NEK2_1	581	586	PF00069	0.525
MOD_NEK2_1	66	71	PF00069	0.579
MOD_NEK2_1	685	690	PF00069	0.508
MOD_NEK2_1	709	714	PF00069	0.360
MOD_NEK2_1	738	743	PF00069	0.614
MOD_NEK2_1	756	761	PF00069	0.343
MOD_NEK2_1	764	769	PF00069	0.461
MOD_NEK2_1	785	790	PF00069	0.442
MOD_NEK2_1	868	873	PF00069	0.448
MOD_NEK2_1	885	890	PF00069	0.267
MOD_NEK2_1	941	946	PF00069	0.441
MOD_NEK2_1	992	997	PF00069	0.414
MOD_NEK2_2	1107	1112	PF00069	0.591
MOD_NEK2_2	269	274	PF00069	0.467
MOD_OFUCOSY	141	147	PF10250	0.520
MOD_PIKK_1	1127	1133	PF00454	0.730
MOD_PIKK_1	12	18	PF00454	0.640
MOD_PIKK_1	1303	1309	PF00454	0.513
MOD_PIKK_1	1348	1354	PF00454	0.383
MOD_PIKK_1	156	162	PF00454	0.541
MOD_PIKK_1	5	11	PF00454	0.686
MOD_PIKK_1	623	629	PF00454	0.488
MOD_PK_1	1293	1299	PF00069	0.489
MOD_PK_1	292	298	PF00069	0.369
MOD_PK_1	639	645	PF00069	0.516
MOD_PK_1	839	845	PF00069	0.324
MOD_PKA_1	103	109	PF00069	0.518
MOD_PKA_1	1209	1215	PF00069	0.532
MOD_PKA_1	1551	1557	PF00069	0.513
MOD_PKA_1	172	178	PF00069	0.623
MOD_PKA_1	464	470	PF00069	0.511
MOD_PKA_1	67	73	PF00069	0.619
MOD_PKA_2	102	108	PF00069	0.634
MOD_PKA_2	1126	1132	PF00069	0.623
MOD_PKA_2	1133	1139	PF00069	0.580
MOD_PKA_2	1209	1215	PF00069	0.615
MOD_PKA_2	1303	1309	PF00069	0.411
MOD_PKA_2	1310	1316	PF00069	0.411
MOD_PKA_2	1459	1465	PF00069	0.411
MOD_PKA_2	1512	1518	PF00069	0.513
MOD_PKA_2	1551	1557	PF00069	0.411
MOD_PKA_2	172	178	PF00069	0.623
MOD_PKA_2	202	208	PF00069	0.497
MOD_PKA_2	284	290	PF00069	0.385
MOD_PKA_2	66	72	PF00069	0.594
MOD_PKB_1	837	845	PF00069	0.321
MOD_Plk_1	1020	1026	PF00069	0.621
MOD_Plk_1	116	122	PF00069	0.560
MOD_Plk_1	259	265	PF00069	0.444
MOD_Plk_1	367	373	PF00069	0.495
MOD_Plk_1	581	587	PF00069	0.525
MOD_Plk_4	1200	1206	PF00069	0.618
MOD_Plk_4	1382	1388	PF00069	0.513
MOD_Plk_4	1413	1419	PF00069	0.513
MOD_Plk_4	1557	1563	PF00069	0.549
MOD_Plk_4	259	265	PF00069	0.542
MOD_Plk_4	279	285	PF00069	0.478
MOD_Plk_4	299	305	PF00069	0.191
MOD_Plk_4	310	316	PF00069	0.347
MOD_Plk_4	322	328	PF00069	0.551
MOD_Plk_4	344	350	PF00069	0.382
MOD_Plk_4	466	472	PF00069	0.462
MOD_Plk_4	474	480	PF00069	0.455
MOD_Plk_4	568	574	PF00069	0.430
MOD_Plk_4	680	686	PF00069	0.450
MOD_Plk_4	698	704	PF00069	0.496
MOD_Plk_4	759	765	PF00069	0.446
MOD_Plk_4	785	791	PF00069	0.440
MOD_Plk_4	868	874	PF00069	0.548
MOD_Plk_4	885	891	PF00069	0.272
MOD_Plk_4	941	947	PF00069	0.431
MOD_ProDKin_1	1119	1125	PF00069	0.790
MOD_ProDKin_1	1181	1187	PF00069	0.653
MOD_ProDKin_1	1220	1226	PF00069	0.645
MOD_ProDKin_1	141	147	PF00069	0.661
MOD_ProDKin_1	1455	1461	PF00069	0.513
MOD_ProDKin_1	483	489	PF00069	0.582
MOD_ProDKin_1	491	497	PF00069	0.527
MOD_ProDKin_1	52	58	PF00069	0.413
MOD_ProDKin_1	933	939	PF00069	0.445
MOD_ProDKin_1	971	977	PF00069	0.463
MOD_SUMO_for_1	1422	1425	PF00179	0.513
MOD_SUMO_rev_2	1416	1424	PF00179	0.411
MOD_SUMO_rev_2	175	181	PF00179	0.609
MOD_SUMO_rev_2	416	425	PF00179	0.379
MOD_SUMO_rev_2	566	572	PF00179	0.427
MOD_SUMO_rev_2	61	66	PF00179	0.600
TRG_DiLeu_BaEn_1	152	157	PF01217	0.563
TRG_DiLeu_BaEn_1	1557	1562	PF01217	0.655
TRG_DiLeu_BaEn_1	185	190	PF01217	0.583
TRG_DiLeu_BaEn_1	747	752	PF01217	0.510
TRG_DiLeu_BaEn_1	987	992	PF01217	0.483
TRG_DiLeu_LyEn_5	747	752	PF01217	0.510
TRG_ENDOCYTIC_2	1318	1321	PF00928	0.360
TRG_ENDOCYTIC_2	242	245	PF00928	0.465
TRG_ENDOCYTIC_2	304	307	PF00928	0.469
TRG_ENDOCYTIC_2	327	330	PF00928	0.572
TRG_ENDOCYTIC_2	391	394	PF00928	0.462
TRG_ENDOCYTIC_2	409	412	PF00928	0.324
TRG_ENDOCYTIC_2	552	555	PF00928	0.429
TRG_ENDOCYTIC_2	556	559	PF00928	0.414
TRG_ENDOCYTIC_2	676	679	PF00928	0.418
TRG_ENDOCYTIC_2	851	854	PF00928	0.449
TRG_ENDOCYTIC_2	932	935	PF00928	0.472
TRG_ER_diArg_1	1551	1553	PF00400	0.474
TRG_ER_diArg_1	171	173	PF00400	0.635
TRG_ER_diArg_1	369	372	PF00400	0.463
TRG_ER_diArg_1	431	433	PF00400	0.471
TRG_ER_diArg_1	487	490	PF00400	0.464
TRG_ER_diArg_1	66	68	PF00400	0.481
TRG_ER_diArg_1	78	81	PF00400	0.402
TRG_ER_diArg_1	961	963	PF00400	0.588
TRG_ER_diArg_1	979	981	PF00400	0.331
TRG_ER_diArg_1	997	999	PF00400	0.307
TRG_NES_CRM1_1	294	309	PF08389	0.352
TRG_NES_CRM1_1	514	528	PF08389	0.334
TRG_NES_CRM1_1	82	94	PF08389	0.505
TRG_Pf-PMV_PEXEL_1	1015	1019	PF00026	0.452
TRG_Pf-PMV_PEXEL_1	1076	1081	PF00026	0.681
TRG_Pf-PMV_PEXEL_1	1447	1451	PF00026	0.513

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P883	Leptomonas seymouri	49%	100%
A4HNV1	Leishmania braziliensis	63%	99%
A4ICP3	Leishmania infantum	99%	100%
E9ASL1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%
Q4Q1Y5	Leishmania major	88%	100%