KREPA4, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

KREPA4, putative

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7XAG1_LEIDO

TriTrypDb:

LdBPK_360750.1 , LdCL_360012400 , LDHU3_36.0940

Length:

268

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7XAG1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XAG1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	209	211	PF00675	0.566
CLV_NRD_NRD_1	51	53	PF00675	0.699
CLV_NRD_NRD_1	61	63	PF00675	0.688
CLV_NRD_NRD_1	76	78	PF00675	0.596
CLV_PCSK_KEX2_1	132	134	PF00082	0.653
CLV_PCSK_KEX2_1	209	211	PF00082	0.566
CLV_PCSK_KEX2_1	51	53	PF00082	0.699
CLV_PCSK_KEX2_1	75	77	PF00082	0.632
CLV_PCSK_PC1ET2_1	132	134	PF00082	0.754
CLV_PCSK_PC1ET2_1	75	77	PF00082	0.717
CLV_PCSK_SKI1_1	12	16	PF00082	0.607
CLV_PCSK_SKI1_1	163	167	PF00082	0.574
CLV_PCSK_SKI1_1	209	213	PF00082	0.515
CLV_PCSK_SKI1_1	242	246	PF00082	0.569
CLV_PCSK_SKI1_1	27	31	PF00082	0.644
CLV_PCSK_SKI1_1	6	10	PF00082	0.596
CLV_PCSK_SKI1_1	62	66	PF00082	0.667
CLV_PCSK_SKI1_1	85	89	PF00082	0.657
DEG_Nend_UBRbox_1	1	4	PF02207	0.767
DEG_SPOP_SBC_1	64	68	PF00917	0.653
DOC_ANK_TNKS_1	260	267	PF00023	0.454
DOC_MAPK_DCC_7	242	251	PF00069	0.525
DOC_MAPK_MEF2A_6	242	251	PF00069	0.525
DOC_USP7_MATH_1	122	126	PF00917	0.721
DOC_USP7_MATH_1	17	21	PF00917	0.793
DOC_USP7_MATH_1	180	184	PF00917	0.686
DOC_USP7_MATH_1	196	200	PF00917	0.784
DOC_USP7_MATH_1	22	26	PF00917	0.691
DOC_USP7_MATH_1	42	46	PF00917	0.608
DOC_WW_Pin1_4	153	158	PF00397	0.548
DOC_WW_Pin1_4	164	169	PF00397	0.496
LIG_14-3-3_CanoR_1	12	22	PF00244	0.653
LIG_14-3-3_CanoR_1	51	56	PF00244	0.678
LIG_14-3-3_CanoR_1	62	71	PF00244	0.686
LIG_14-3-3_CanoR_1	85	93	PF00244	0.763
LIG_FHA_1	135	141	PF00498	0.622
LIG_FHA_1	21	27	PF00498	0.628
LIG_FHA_1	243	249	PF00498	0.500
LIG_LIR_Nem_3	68	74	PF02991	0.625
LIG_MYND_3	246	250	PF01753	0.600
LIG_PCNA_yPIPBox_3	222	236	PF02747	0.518
LIG_SH2_SRC	108	111	PF00017	0.555
LIG_SH2_STAT5	108	111	PF00017	0.573
LIG_SH3_3	241	247	PF00018	0.562
LIG_TRAF2_1	70	73	PF00917	0.604
MOD_CK1_1	153	159	PF00069	0.648
MOD_CK1_1	183	189	PF00069	0.716
MOD_CK1_1	20	26	PF00069	0.668
MOD_CK1_1	200	206	PF00069	0.699
MOD_CK1_1	45	51	PF00069	0.668
MOD_CK1_1	67	73	PF00069	0.652
MOD_CK2_1	22	28	PF00069	0.766
MOD_CK2_1	67	73	PF00069	0.643
MOD_Cter_Amidation	130	133	PF01082	0.668
MOD_GlcNHglycan	124	127	PF01048	0.602
MOD_GlcNHglycan	19	22	PF01048	0.744
MOD_GlcNHglycan	226	229	PF01048	0.483
MOD_GlcNHglycan	40	43	PF01048	0.771
MOD_GlcNHglycan	67	70	PF01048	0.735
MOD_GSK3_1	134	141	PF00069	0.578
MOD_GSK3_1	16	23	PF00069	0.682
MOD_GSK3_1	180	187	PF00069	0.769
MOD_GSK3_1	192	199	PF00069	0.676
MOD_GSK3_1	38	45	PF00069	0.662
MOD_GSK3_1	63	70	PF00069	0.643
MOD_GSK3_1	8	15	PF00069	0.760
MOD_N-GLC_1	12	17	PF02516	0.712
MOD_N-GLC_1	141	146	PF02516	0.572
MOD_N-GLC_1	42	47	PF02516	0.616
MOD_NEK2_1	150	155	PF00069	0.598
MOD_NEK2_1	256	261	PF00069	0.615
MOD_NEK2_1	8	13	PF00069	0.717
MOD_NEK2_2	103	108	PF00069	0.521
MOD_NEK2_2	22	27	PF00069	0.695
MOD_PIKK_1	190	196	PF00454	0.638
MOD_PKA_1	51	57	PF00069	0.691
MOD_PKA_1	62	68	PF00069	0.679
MOD_PKA_2	51	57	PF00069	0.691
MOD_Plk_1	216	222	PF00069	0.351
MOD_Plk_1	27	33	PF00069	0.624
MOD_Plk_4	103	109	PF00069	0.515
MOD_Plk_4	197	203	PF00069	0.703
MOD_Plk_4	45	51	PF00069	0.776
MOD_ProDKin_1	153	159	PF00069	0.543
MOD_ProDKin_1	164	170	PF00069	0.493
MOD_SUMO_rev_2	55	65	PF00179	0.571
TRG_ENDOCYTIC_2	5	8	PF00928	0.558
TRG_ER_diArg_1	208	210	PF00400	0.580
TRG_ER_diArg_1	50	52	PF00400	0.698
TRG_NES_CRM1_1	239	250	PF08389	0.550
TRG_NLS_Bipartite_1	62	79	PF00514	0.530
TRG_Pf-PMV_PEXEL_1	85	90	PF00026	0.661

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFQ8	Leptomonas seymouri	38%	89%
A4HNS9	Leishmania braziliensis	77%	100%
A4ICR5	Leishmania infantum	99%	100%
E9ASI9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q207	Leishmania major	90%	100%