Enriched in surface-labeled proteome protein 18

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Enriched in surface-labeled proteome protein 18

Species:

Leishmania donovani

UniProt:

A0A3S7XAF9_LEIDO

TriTrypDb:

LdBPK_360720.1 , LdCL_360012100 , LDHU3_36.0880

Length:

202

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 5, no: 3
NetGPI	no	yes: 0, no: 8

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Cellular components
Term	Name	Level	Count
GO:0005768	endosome	7	1
GO:0009986	cell surface	2	1
GO:0031410	cytoplasmic vesicle	6	1
GO:0031982	vesicle	4	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0097708	intracellular vesicle	5	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A0A3S7XAF9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XAF9

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	149	153	PF00656	0.434
CLV_NRD_NRD_1	113	115	PF00675	0.654
CLV_PCSK_KEX2_1	113	115	PF00082	0.655
CLV_PCSK_SKI1_1	103	107	PF00082	0.589
CLV_PCSK_SKI1_1	113	117	PF00082	0.598
CLV_PCSK_SKI1_1	17	21	PF00082	0.270
CLV_PCSK_SKI1_1	57	61	PF00082	0.781
CLV_PCSK_SKI1_1	6	10	PF00082	0.553
DEG_APCC_DBOX_1	153	161	PF00400	0.355
DEG_APCC_DBOX_1	16	24	PF00400	0.184

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I8L4	Leptomonas seymouri	49%	97%
A0A1X0P888	Trypanosomatidae	28%	100%
A4HNS6	Leishmania braziliensis	72%	100%
A4ICR8	Leishmania infantum	96%	100%
D0A2N6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	100%
E9ASI6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%
Q4Q210	Leishmania major	88%	100%

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