Zinc-finger_of_a_C2HC-type_putative/Pfam:PF13913

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

zinc-finger of a C2HC-type, putative

Species:

Leishmania donovani

UniProt:

A0A3S7XAD7_LEIDO

TriTrypDb:

LdBPK_360520.1 , LdCL_360010100 , LDHU3_36.0680

Length:

349

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7XAD7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XAD7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	128	130	PF00675	0.534
CLV_NRD_NRD_1	159	161	PF00675	0.757
CLV_NRD_NRD_1	253	255	PF00675	0.745
CLV_PCSK_KEX2_1	127	129	PF00082	0.540
CLV_PCSK_KEX2_1	159	161	PF00082	0.660
CLV_PCSK_KEX2_1	200	202	PF00082	0.558
CLV_PCSK_KEX2_1	253	255	PF00082	0.760
CLV_PCSK_KEX2_1	34	36	PF00082	0.472
CLV_PCSK_PC1ET2_1	127	129	PF00082	0.540
CLV_PCSK_PC1ET2_1	200	202	PF00082	0.601
CLV_PCSK_PC1ET2_1	34	36	PF00082	0.472
CLV_PCSK_SKI1_1	128	132	PF00082	0.531
CLV_PCSK_SKI1_1	197	201	PF00082	0.571
CLV_PCSK_SKI1_1	31	35	PF00082	0.452
DEG_SPOP_SBC_1	169	173	PF00917	0.715
DOC_PP4_FxxP_1	152	155	PF00568	0.755
DOC_PP4_FxxP_1	294	297	PF00568	0.728
DOC_USP7_MATH_1	195	199	PF00917	0.498
DOC_USP7_MATH_1	215	219	PF00917	0.438
DOC_USP7_MATH_1	233	237	PF00917	0.750
DOC_USP7_MATH_1	242	246	PF00917	0.754
DOC_USP7_MATH_1	56	60	PF00917	0.664
DOC_USP7_MATH_1	75	79	PF00917	0.697
DOC_USP7_UBL2_3	123	127	PF12436	0.502
DOC_USP7_UBL2_3	53	57	PF12436	0.755
DOC_WW_Pin1_4	173	178	PF00397	0.680
DOC_WW_Pin1_4	217	222	PF00397	0.559
DOC_WW_Pin1_4	295	300	PF00397	0.688
LIG_14-3-3_CanoR_1	247	257	PF00244	0.762
LIG_ActinCP_TwfCPI_2	294	303	PF01115	0.576
LIG_BRCT_BRCA1_1	309	313	PF00533	0.615
LIG_FHA_1	161	167	PF00498	0.700
LIG_FHA_1	250	256	PF00498	0.758
LIG_FHA_1	296	302	PF00498	0.645
LIG_FHA_1	6	12	PF00498	0.376
LIG_LIR_Gen_1	109	117	PF02991	0.408
LIG_LIR_Nem_3	109	115	PF02991	0.408
LIG_SH2_NCK_1	175	179	PF00017	0.705
LIG_SH2_STAP1	29	33	PF00017	0.420
LIG_SH2_STAT5	175	178	PF00017	0.707
LIG_SH3_3	211	217	PF00018	0.691
LIG_SH3_3	294	300	PF00018	0.777
LIG_SH3_3	37	43	PF00018	0.531
LIG_SH3_4	53	60	PF00018	0.745
MOD_CDC14_SPxK_1	220	223	PF00782	0.562
MOD_CDK_SPxK_1	217	223	PF00069	0.561
MOD_CK1_1	173	179	PF00069	0.637
MOD_CK1_1	249	255	PF00069	0.736
MOD_GlcNHglycan	17	20	PF01048	0.408
MOD_GlcNHglycan	197	200	PF01048	0.550
MOD_GlcNHglycan	235	238	PF01048	0.741
MOD_GlcNHglycan	244	247	PF01048	0.772
MOD_GlcNHglycan	248	251	PF01048	0.739
MOD_GlcNHglycan	63	66	PF01048	0.669
MOD_GlcNHglycan	77	80	PF01048	0.603
MOD_GSK3_1	165	172	PF00069	0.664
MOD_GSK3_1	205	212	PF00069	0.559
MOD_GSK3_1	215	222	PF00069	0.705
MOD_GSK3_1	242	249	PF00069	0.772
MOD_GSK3_1	56	63	PF00069	0.609
MOD_GSK3_1	75	82	PF00069	0.701
MOD_N-GLC_1	169	174	PF02516	0.707
MOD_N-GLC_1	262	267	PF02516	0.659
MOD_N-GLC_1	335	340	PF02516	0.599
MOD_NEK2_1	131	136	PF00069	0.564
MOD_NEK2_1	209	214	PF00069	0.648
MOD_NEK2_1	231	236	PF00069	0.711
MOD_PKA_2	246	252	PF00069	0.768
MOD_PKA_2	302	308	PF00069	0.673
MOD_Plk_1	262	268	PF00069	0.707
MOD_Plk_1	335	341	PF00069	0.616
MOD_Plk_4	205	211	PF00069	0.584
MOD_ProDKin_1	173	179	PF00069	0.678
MOD_ProDKin_1	217	223	PF00069	0.561
MOD_ProDKin_1	295	301	PF00069	0.690
TRG_ER_diArg_1	128	130	PF00400	0.617
TRG_ER_diArg_1	158	160	PF00400	0.694
TRG_ER_diArg_1	253	255	PF00400	0.748
TRG_NLS_MonoExtC_3	126	132	PF00514	0.546
TRG_Pf-PMV_PEXEL_1	331	335	PF00026	0.710
TRG_Pf-PMV_PEXEL_1	81	86	PF00026	0.626

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HYW4	Leptomonas seymouri	59%	95%
A0A0S4JLV6	Bodo saltans	36%	100%
A0A1X0P958	Trypanosomatidae	42%	100%
A0A3R7MA87	Trypanosoma rangeli	43%	100%
A4HNQ7	Leishmania braziliensis	78%	98%
A4ICT8	Leishmania infantum	99%	100%
E9ASG6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
Q4Q229	Leishmania major	94%	100%
V5BQI1	Trypanosoma cruzi	42%	100%