Protein_C21orf2_homolog_putative/GeneDB:LmjF.36.0 710

Quick info Annotations Localization Abundance Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Protein C21orf2 homolog, putative

Species:

Leishmania donovani

UniProt:

A0A3S7XAD6_LEIDO

TriTrypDb:

LdBPK_360770.1 , LdCL_360012600 , LDHU3_36.0960

Length:

259

Annotations

Annotations by Jardim et al.

Membrane associated proteins, C21orf2 homolog Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Show entries

Cellular components
Term	Name	Level	Count
GO:0005929	cilium	4	10
GO:0042995	cell projection	2	10
GO:0043226	organelle	2	10
GO:0043227	membrane-bounded organelle	3	10
GO:0110165	cellular anatomical entity	1	10
GO:0120025	plasma membrane bounded cell projection	3	10

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Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A0A3S7XAD6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XAD6

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	132	134	PF00675	0.303
CLV_NRD_NRD_1	73	75	PF00675	0.244
CLV_PCSK_KEX2_1	138	140	PF00082	0.305
CLV_PCSK_PC1ET2_1	138	140	PF00082	0.305
CLV_PCSK_SKI1_1	10	14	PF00082	0.476
CLV_PCSK_SKI1_1	138	142	PF00082	0.285
CLV_PCSK_SKI1_1	203	207	PF00082	0.627
CLV_PCSK_SKI1_1	214	218	PF00082	0.418
CLV_PCSK_SKI1_1	82	86	PF00082	0.253
DEG_APCC_DBOX_1	213	221	PF00400	0.542

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7V8	Leptomonas seymouri	65%	100%
A0A0S4JS78	Bodo saltans	45%	100%
A4HNT1	Leishmania braziliensis	83%	100%
A4ICR3	Leishmania infantum	100%	100%
D0A2P1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	94%
E9ASJ1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
O43822	Homo sapiens	31%	100%
Q4Q205	Leishmania major	97%	100%
Q8C6G1	Mus musculus	36%	100%
Q9BV99	Homo sapiens	31%	100%

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