A very conserved component of the ER translocon. Localization: ER (by homology)
Uncharacterized Protein, Uncharacterized
Source | Evidence on protein | Close homologs |
---|---|---|
Cuervo et al. | no | yes: 0 |
Hassani et al. | no | yes: 0 |
Forrest at al. (metacyclic) | no | yes: 0 |
Forrest at al. (procyclic) | no | yes: 0 |
Silverman et al. | no | yes: 0 |
Pissara et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
Pires et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
Silverman et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
Jamdhade et al. | yes | yes: 18 |
Source | Evidence on protein | Close homologs |
---|---|---|
DeepLoc | ||
SignalP6 | no | yes: 0, no: 11 |
NetGPI | no | yes: 0, no: 11 |
Term | Name | Level | Count |
---|---|---|---|
GO:0016020 | membrane | 2 | 11 |
GO:0110165 | cellular anatomical entity | 1 | 11 |
GO:0032991 | protein-containing complex | 1 | 1 |
GO:0072546 | EMC complex | 3 | 1 |
GO:0098796 | membrane protein complex | 2 | 1 |
GO:0140534 | endoplasmic reticulum protein-containing complex | 2 | 1 |
Related structures:
AlphaFold database: A0A3S7XAB1
Leishmania | From | To | Domain/Motif | Score |
---|---|---|---|---|
CLV_PCSK_KEX2_1 | 249 | 251 | PF00082 | 0.626 |
CLV_PCSK_KEX2_1 | 257 | 259 | PF00082 | 0.721 |
CLV_PCSK_PC1ET2_1 | 249 | 251 | PF00082 | 0.629 |
CLV_PCSK_PC1ET2_1 | 257 | 259 | PF00082 | 0.721 |
CLV_PCSK_SKI1_1 | 214 | 218 | PF00082 | 0.503 |
CLV_PCSK_SKI1_1 | 249 | 253 | PF00082 | 0.611 |
CLV_PCSK_SKI1_1 | 60 | 64 | PF00082 | 0.459 |
DOC_CYCLIN_RxL_1 | 57 | 64 | PF00134 | 0.272 |
DOC_MAPK_DCC_7 | 14 | 24 | PF00069 | 0.357 |
DOC_MAPK_FxFP_2 | 138 | 141 | PF00069 | 0.552 |
DOC_MAPK_MEF2A_6 | 14 | 23 | PF00069 | 0.385 |
DOC_MAPK_MEF2A_6 | 32 | 39 | PF00069 | 0.404 |
DOC_PP2B_PxIxI_1 | 19 | 25 | PF00149 | 0.335 |
DOC_PP4_FxxP_1 | 138 | 141 | PF00568 | 0.552 |
DOC_USP7_MATH_1 | 203 | 207 | PF00917 | 0.512 |
DOC_WW_Pin1_4 | 38 | 43 | PF00397 | 0.244 |
DOC_WW_Pin1_4 | 67 | 72 | PF00397 | 0.272 |
LIG_BRCT_BRCA1_1 | 126 | 130 | PF00533 | 0.300 |
LIG_BRCT_BRCA1_1 | 142 | 146 | PF00533 | 0.447 |
LIG_BRCT_BRCA1_1 | 167 | 171 | PF00533 | 0.300 |
LIG_EH1_1 | 32 | 40 | PF00400 | 0.408 |
LIG_LIR_Gen_1 | 15 | 24 | PF02991 | 0.300 |
LIG_LIR_Gen_1 | 211 | 219 | PF02991 | 0.351 |
LIG_LIR_Nem_3 | 127 | 133 | PF02991 | 0.293 |
LIG_LIR_Nem_3 | 15 | 19 | PF02991 | 0.288 |
LIG_LIR_Nem_3 | 168 | 173 | PF02991 | 0.300 |
LIG_LIR_Nem_3 | 211 | 215 | PF02991 | 0.318 |
LIG_MLH1_MIPbox_1 | 126 | 130 | PF16413 | 0.300 |
LIG_MLH1_MIPbox_1 | 167 | 171 | PF16413 | 0.300 |
LIG_NRBOX | 179 | 185 | PF00104 | 0.303 |
LIG_NRP_CendR_1 | 257 | 259 | PF00754 | 0.744 |
LIG_PCNA_PIPBox_1 | 122 | 131 | PF02747 | 0.300 |
LIG_Pex14_2 | 129 | 133 | PF04695 | 0.300 |
LIG_Pex14_2 | 212 | 216 | PF04695 | 0.395 |
LIG_PTB_Apo_2 | 157 | 164 | PF02174 | 0.533 |
LIG_PTB_Phospho_1 | 157 | 163 | PF10480 | 0.533 |
LIG_SH2_CRK | 58 | 62 | PF00017 | 0.259 |
LIG_SH2_GRB2like | 234 | 237 | PF00017 | 0.349 |
LIG_SH2_NCK_1 | 234 | 238 | PF00017 | 0.360 |
LIG_SH2_PTP2 | 34 | 37 | PF00017 | 0.408 |
LIG_SH2_SRC | 234 | 237 | PF00017 | 0.373 |
LIG_SH2_STAT5 | 128 | 131 | PF00017 | 0.286 |
LIG_SH2_STAT5 | 163 | 166 | PF00017 | 0.300 |
LIG_SH2_STAT5 | 170 | 173 | PF00017 | 0.300 |
LIG_SH2_STAT5 | 34 | 37 | PF00017 | 0.408 |
LIG_SH3_3 | 14 | 20 | PF00018 | 0.300 |
LIG_SH3_3 | 39 | 45 | PF00018 | 0.325 |
LIG_SH3_3 | 89 | 95 | PF00018 | 0.336 |
LIG_SUMO_SIM_anti_2 | 155 | 160 | PF11976 | 0.533 |
LIG_UBA3_1 | 105 | 110 | PF00899 | 0.274 |
LIG_UBA3_1 | 81 | 88 | PF00899 | 0.352 |
MOD_CDC14_SPxK_1 | 41 | 44 | PF00782 | 0.325 |
MOD_CDK_SPxK_1 | 38 | 44 | PF00069 | 0.325 |
MOD_CK1_1 | 70 | 76 | PF00069 | 0.356 |
MOD_GlcNHglycan | 130 | 133 | PF01048 | 0.300 |
MOD_GlcNHglycan | 174 | 177 | PF01048 | 0.420 |
MOD_GlcNHglycan | 194 | 197 | PF01048 | 0.471 |
MOD_GlcNHglycan | 205 | 208 | PF01048 | 0.635 |
MOD_GlcNHglycan | 63 | 66 | PF01048 | 0.503 |
MOD_GSK3_1 | 124 | 131 | PF00069 | 0.309 |
MOD_GSK3_1 | 188 | 195 | PF00069 | 0.455 |
MOD_N-GLC_1 | 192 | 197 | PF02516 | 0.637 |
MOD_NEK2_1 | 124 | 129 | PF00069 | 0.325 |
MOD_NEK2_1 | 172 | 177 | PF00069 | 0.301 |
MOD_PIKK_1 | 244 | 250 | PF00454 | 0.450 |
MOD_Plk_1 | 192 | 198 | PF00069 | 0.469 |
MOD_Plk_4 | 124 | 130 | PF00069 | 0.322 |
MOD_Plk_4 | 165 | 171 | PF00069 | 0.304 |
MOD_Plk_4 | 33 | 39 | PF00069 | 0.336 |
MOD_ProDKin_1 | 38 | 44 | PF00069 | 0.244 |
MOD_ProDKin_1 | 67 | 73 | PF00069 | 0.272 |
MOD_SUMO_for_1 | 86 | 89 | PF00179 | 0.297 |
TRG_DiLeu_BaEn_1 | 4 | 9 | PF01217 | 0.533 |
TRG_DiLeu_BaLyEn_6 | 17 | 22 | PF01217 | 0.300 |
TRG_ENDOCYTIC_2 | 170 | 173 | PF00928 | 0.300 |
TRG_ENDOCYTIC_2 | 34 | 37 | PF00928 | 0.300 |
TRG_ENDOCYTIC_2 | 58 | 61 | PF00928 | 0.259 |
TRG_NLS_MonoExtN_4 | 246 | 253 | PF00514 | 0.440 |
TRG_Pf-PMV_PEXEL_1 | 152 | 157 | PF00026 | 0.314 |
Protein | Taxonomy | Sequence identity | Coverage |
---|---|---|---|
A0A0N0P702 | Leptomonas seymouri | 78% | 100% |
A0A0S4JI82 | Bodo saltans | 52% | 100% |
A0A1X0P9P9 | Trypanosomatidae | 62% | 100% |
A0A422P2C0 | Trypanosoma rangeli | 60% | 100% |
A4HNP4 | Leishmania braziliensis | 89% | 100% |
A4ICV1 | Leishmania infantum | 100% | 100% |
A7A082 | Saccharomyces cerevisiae (strain YJM789) | 30% | 100% |
B3LQQ2 | Saccharomyces cerevisiae (strain RM11-1a) | 28% | 100% |
B5VLV9 | Saccharomyces cerevisiae (strain AWRI1631) | 28% | 100% |
D0A2K0 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 58% | 100% |
E9ASF3 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 97% | 100% |
P36039 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 30% | 100% |
Q3ZCB8 | Bos taurus | 34% | 99% |
Q4Q242 | Leishmania major | 99% | 100% |
Q54YN3 | Dictyostelium discoideum | 29% | 82% |
Q5R7C1 | Pongo abelii | 34% | 99% |
Q5U2V8 | Rattus norvegicus | 34% | 99% |
Q7SXW4 | Danio rerio | 35% | 99% |
Q99KI3 | Mus musculus | 34% | 99% |
Q9P0I2 | Homo sapiens | 34% | 99% |
Q9P787 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 35% | 100% |
V5DRR4 | Trypanosoma cruzi | 60% | 100% |