LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7XA93_LEIDO
TriTrypDb:
LdBPK_360410.1 , LdCL_360008900 , LDHU3_36.0530
Length:
153

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 1, no: 10
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0016020 membrane 2 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A0A3S7XA93
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XA93

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 101 103 PF00675 0.486
CLV_NRD_NRD_1 147 149 PF00675 0.615
CLV_NRD_NRD_1 150 152 PF00675 0.658
CLV_NRD_NRD_1 30 32 PF00675 0.490
CLV_PCSK_KEX2_1 29 31 PF00082 0.504
CLV_PCSK_KEX2_1 99 101 PF00082 0.496
CLV_PCSK_PC1ET2_1 99 101 PF00082 0.496
CLV_PCSK_PC7_1 26 32 PF00082 0.510
CLV_PCSK_SKI1_1 31 35 PF00082 0.512
DOC_USP7_MATH_1 112 116 PF00917 0.705
DOC_USP7_MATH_1 62 66 PF00917 0.720
DOC_USP7_MATH_1 70 74 PF00917 0.619
DOC_USP7_MATH_1 86 90 PF00917 0.568
DOC_USP7_UBL2_3 145 149 PF12436 0.578
DOC_WW_Pin1_4 113 118 PF00397 0.757
DOC_WW_Pin1_4 44 49 PF00397 0.713
DOC_WW_Pin1_4 60 65 PF00397 0.665
LIG_BIR_II_1 1 5 PF00653 0.619
LIG_SH2_STAT3 75 78 PF00017 0.743
LIG_SH2_STAT3 90 93 PF00017 0.419
LIG_SH2_STAT5 53 56 PF00017 0.712
LIG_SH2_STAT5 90 93 PF00017 0.513
LIG_SH3_3 118 124 PF00018 0.745
LIG_UBA3_1 91 99 PF00899 0.581
MOD_CK1_1 63 69 PF00069 0.701
MOD_CK1_1 71 77 PF00069 0.674
MOD_CK2_1 138 144 PF00069 0.590
MOD_GlcNHglycan 110 113 PF01048 0.687
MOD_GlcNHglycan 65 68 PF01048 0.654
MOD_GlcNHglycan 70 73 PF01048 0.636
MOD_GlcNHglycan 75 78 PF01048 0.596
MOD_GSK3_1 104 111 PF00069 0.655
MOD_GSK3_1 49 56 PF00069 0.670
MOD_PIKK_1 123 129 PF00454 0.771
MOD_PIKK_1 132 138 PF00454 0.751
MOD_PIKK_1 80 86 PF00454 0.627
MOD_Plk_1 138 144 PF00069 0.650
MOD_Plk_1 56 62 PF00069 0.761
MOD_Plk_4 49 55 PF00069 0.727
MOD_Plk_4 86 92 PF00069 0.621
MOD_ProDKin_1 113 119 PF00069 0.759
MOD_ProDKin_1 44 50 PF00069 0.713
MOD_ProDKin_1 60 66 PF00069 0.663
TRG_ER_diArg_1 100 102 PF00400 0.501
TRG_ER_diArg_1 29 31 PF00400 0.519
TRG_NLS_MonoExtC_3 147 152 PF00514 0.635
TRG_NLS_MonoExtN_4 145 152 PF00514 0.636

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P7D8 Leptomonas seymouri 50% 81%
A0A0S4JKZ0 Bodo saltans 40% 100%
A0A1X0P8A6 Trypanosomatidae 32% 100%
A0A422P2F7 Trypanosoma rangeli 43% 100%
A4HNP6 Leishmania braziliensis 73% 96%
A4ICU9 Leishmania infantum 100% 100%
D0A2K4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 42% 100%
E9ASF5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
Q4Q240 Leishmania major 92% 100%
V5BV99 Trypanosoma cruzi 44% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS