Transmembrane amino acid transporter family protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

amino acid permease, putative

Species:

Leishmania donovani

UniProt:

A0A3S7XA86_LEIDO

TriTrypDb:

LdBPK_355320.1 , LdCL_350059000 , LDHU3_35.7080

Length:

410

Annotations

LeishMANIAdb annotations

An enormously expanded group of various amino acid transporters.. Localization: Cell surface (by feature)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 2
Forrest at al. (procyclic)	no	yes: 2
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 39

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 1, no: 100
NetGPI	no	yes: 0, no: 101

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	90
GO:0110165	cellular anatomical entity	1	90
GO:0005634	nucleus	5	1
GO:0005737	cytoplasm	2	1
GO:0005886	plasma membrane	3	1
GO:0020016	ciliary pocket	2	1
GO:0020023	kinetoplast	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1

Expansion

Sequence features

A0A3S7XA86

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XA86

Function

Biological processes
Term	Name	Level	Count
GO:0003333	amino acid transmembrane transport	5	12
GO:0006810	transport	3	12
GO:0006865	amino acid transport	5	12
GO:0009987	cellular process	1	12
GO:0015849	organic acid transport	5	12
GO:0051179	localization	1	12
GO:0051234	establishment of localization	2	12
GO:0055085	transmembrane transport	2	12
GO:0071702	organic substance transport	4	12
GO:0071705	nitrogen compound transport	4	12
GO:1903825	organic acid transmembrane transport	3	12
GO:1905039	carboxylic acid transmembrane transport	4	12
GO:0006811	monoatomic ion transport	4	1
GO:0006812	monoatomic cation transport	5	1
GO:0006820	monoatomic anion transport	5	1
GO:0015711	organic anion transport	5	1
GO:0015802	basic amino acid transport	6	1
GO:0015819	lysine transport	6	1
GO:0046942	carboxylic acid transport	6	1

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	11
GO:0016787	hydrolase activity	2	11
GO:0005215	transporter activity	1	12
GO:0005342	organic acid transmembrane transporter activity	3	12
GO:0015171	amino acid transmembrane transporter activity	5	12
GO:0015179	L-amino acid transmembrane transporter activity	6	12
GO:0022857	transmembrane transporter activity	2	12
GO:0046943	carboxylic acid transmembrane transporter activity	4	12
GO:0008324	monoatomic cation transmembrane transporter activity	4	1
GO:0008509	monoatomic anion transmembrane transporter activity	4	1
GO:0008514	organic anion transmembrane transporter activity	5	1
GO:0015075	monoatomic ion transmembrane transporter activity	3	1
GO:0015174	basic amino acid transmembrane transporter activity	6	1
GO:0015189	L-lysine transmembrane transporter activity	5	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	34	38	PF00656	0.168
CLV_PCSK_SKI1_1	196	200	PF00082	0.502
CLV_PCSK_SKI1_1	222	226	PF00082	0.267
CLV_PCSK_SKI1_1	370	374	PF00082	0.332
CLV_PCSK_SKI1_1	78	82	PF00082	0.266
CLV_PCSK_SKI1_1	90	94	PF00082	0.296
DEG_Nend_UBRbox_1	1	4	PF02207	0.509
DEG_SCF_FBW7_1	253	260	PF00400	0.332
DOC_CKS1_1	111	116	PF01111	0.292
DOC_CYCLIN_yCln2_LP_2	118	124	PF00134	0.286
DOC_CYCLIN_yCln2_LP_2	199	205	PF00134	0.323
DOC_MAPK_FxFP_2	363	366	PF00069	0.327
DOC_MAPK_gen_1	149	158	PF00069	0.360
DOC_MAPK_HePTP_8	193	205	PF00069	0.278
DOC_MAPK_MEF2A_6	196	205	PF00069	0.246
DOC_MAPK_MEF2A_6	231	239	PF00069	0.471
DOC_MAPK_MEF2A_6	298	305	PF00069	0.445
DOC_PP2B_LxvP_1	199	202	PF13499	0.323
DOC_PP2B_LxvP_1	29	32	PF13499	0.324
DOC_PP4_FxxP_1	363	366	PF00568	0.323
DOC_WW_Pin1_4	110	115	PF00397	0.292
DOC_WW_Pin1_4	253	258	PF00397	0.298
LIG_14-3-3_CanoR_1	231	236	PF00244	0.533
LIG_AP2alpha_2	268	270	PF02296	0.155
LIG_BRCT_BRCA1_1	211	215	PF00533	0.338
LIG_CtBP_PxDLS_1	383	387	PF00389	0.355
LIG_DLG_GKlike_1	231	239	PF00625	0.354
LIG_EH1_1	164	172	PF00400	0.339
LIG_EH1_1	41	49	PF00400	0.303
LIG_eIF4E_1	244	250	PF01652	0.382
LIG_FHA_1	111	117	PF00498	0.338
LIG_FHA_1	162	168	PF00498	0.304
LIG_FHA_1	238	244	PF00498	0.331
LIG_FHA_1	254	260	PF00498	0.197
LIG_FHA_1	310	316	PF00498	0.457
LIG_FHA_1	326	332	PF00498	0.257
LIG_FHA_1	342	348	PF00498	0.472
LIG_FHA_2	32	38	PF00498	0.323
LIG_GBD_Chelix_1	213	221	PF00786	0.358
LIG_GBD_Chelix_1	245	253	PF00786	0.312
LIG_GBD_Chelix_1	348	356	PF00786	0.350
LIG_LIR_Apic_2	360	366	PF02991	0.300
LIG_LIR_Gen_1	189	198	PF02991	0.333
LIG_LIR_Gen_1	283	292	PF02991	0.266
LIG_LIR_Gen_1	299	306	PF02991	0.450
LIG_LIR_Gen_1	336	346	PF02991	0.312
LIG_LIR_Gen_1	404	410	PF02991	0.305
LIG_LIR_Gen_1	72	81	PF02991	0.446
LIG_LIR_Nem_3	110	115	PF02991	0.239
LIG_LIR_Nem_3	189	193	PF02991	0.329
LIG_LIR_Nem_3	212	218	PF02991	0.311
LIG_LIR_Nem_3	299	305	PF02991	0.462
LIG_LIR_Nem_3	404	408	PF02991	0.311
LIG_LIR_Nem_3	72	76	PF02991	0.451
LIG_MYND_1	117	121	PF01753	0.147
LIG_PDZ_Class_2	405	410	PF00595	0.415
LIG_Pex14_1	91	95	PF04695	0.318
LIG_SH2_CRK	173	177	PF00017	0.445
LIG_SH2_CRK	218	222	PF00017	0.434
LIG_SH2_NCK_1	73	77	PF00017	0.436
LIG_SH2_PTP2	104	107	PF00017	0.288
LIG_SH2_PTP2	290	293	PF00017	0.330
LIG_SH2_SRC	73	76	PF00017	0.472
LIG_SH2_STAP1	282	286	PF00017	0.288
LIG_SH2_STAT5	104	107	PF00017	0.292
LIG_SH2_STAT5	122	125	PF00017	0.269
LIG_SH2_STAT5	155	158	PF00017	0.393
LIG_SH2_STAT5	175	178	PF00017	0.274
LIG_SH2_STAT5	190	193	PF00017	0.234
LIG_SH2_STAT5	244	247	PF00017	0.308
LIG_SH2_STAT5	252	255	PF00017	0.316
LIG_SH2_STAT5	290	293	PF00017	0.340
LIG_SH2_STAT5	60	63	PF00017	0.317
LIG_SH3_3	111	117	PF00018	0.244
LIG_SH3_3	118	124	PF00018	0.244
LIG_SH3_3	137	143	PF00018	0.330
LIG_SH3_3	290	296	PF00018	0.269
LIG_SUMO_SIM_anti_2	127	136	PF11976	0.361
LIG_SUMO_SIM_anti_2	344	350	PF11976	0.277
LIG_SUMO_SIM_par_1	104	110	PF11976	0.326
LIG_SUMO_SIM_par_1	27	34	PF11976	0.292
LIG_SUMO_SIM_par_1	54	59	PF11976	0.300
LIG_SxIP_EBH_1	140	152	PF03271	0.358
LIG_TYR_ITIM	171	176	PF00017	0.433
LIG_TYR_ITIM	188	193	PF00017	0.278
LIG_TYR_ITIM	242	247	PF00017	0.294
LIG_UBA3_1	141	149	PF00899	0.335
LIG_WRC_WIRS_1	205	210	PF05994	0.320
LIG_WRC_WIRS_1	281	286	PF05994	0.335
LIG_WRC_WIRS_1	402	407	PF05994	0.397
MOD_CK1_1	20	26	PF00069	0.328
MOD_CK1_1	333	339	PF00069	0.256
MOD_CK1_1	401	407	PF00069	0.316
MOD_CK2_1	189	195	PF00069	0.330
MOD_GlcNHglycan	167	170	PF01048	0.341
MOD_GlcNHglycan	332	335	PF01048	0.271
MOD_GlcNHglycan	7	10	PF01048	0.353
MOD_GSK3_1	161	168	PF00069	0.312
MOD_GSK3_1	231	238	PF00069	0.484
MOD_GSK3_1	253	260	PF00069	0.285
MOD_GSK3_1	326	333	PF00069	0.304
MOD_GSK3_1	357	364	PF00069	0.296
MOD_N-GLC_1	17	22	PF02516	0.354
MOD_N-GLC_1	257	262	PF02516	0.520
MOD_NEK2_1	126	131	PF00069	0.291
MOD_NEK2_1	165	170	PF00069	0.330
MOD_NEK2_1	17	22	PF00069	0.325
MOD_NEK2_1	235	240	PF00069	0.344
MOD_NEK2_1	326	331	PF00069	0.264
MOD_NEK2_1	341	346	PF00069	0.247
MOD_NEK2_1	356	361	PF00069	0.295
MOD_NEK2_1	398	403	PF00069	0.292
MOD_Plk_1	127	133	PF00069	0.318
MOD_Plk_1	17	23	PF00069	0.460
MOD_Plk_4	161	167	PF00069	0.297
MOD_Plk_4	186	192	PF00069	0.264
MOD_Plk_4	209	215	PF00069	0.329
MOD_Plk_4	326	332	PF00069	0.313
MOD_Plk_4	333	339	PF00069	0.344
MOD_Plk_4	401	407	PF00069	0.278
MOD_Plk_4	51	57	PF00069	0.321
MOD_ProDKin_1	110	116	PF00069	0.292
MOD_ProDKin_1	253	259	PF00069	0.298
TRG_DiLeu_BaLyEn_6	114	119	PF01217	0.258
TRG_ENDOCYTIC_2	104	107	PF00928	0.297
TRG_ENDOCYTIC_2	122	125	PF00928	0.306
TRG_ENDOCYTIC_2	155	158	PF00928	0.337
TRG_ENDOCYTIC_2	173	176	PF00928	0.371
TRG_ENDOCYTIC_2	190	193	PF00928	0.295
TRG_ENDOCYTIC_2	218	221	PF00928	0.442
TRG_ENDOCYTIC_2	244	247	PF00928	0.293
TRG_ENDOCYTIC_2	267	270	PF00928	0.273
TRG_ENDOCYTIC_2	290	293	PF00928	0.331
TRG_ENDOCYTIC_2	73	76	PF00928	0.436
TRG_NES_CRM1_1	59	74	PF08389	0.252

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P285	Leptomonas seymouri	24%	83%
A0A0N0P5D2	Leptomonas seymouri	24%	85%
A0A0N0P613	Leptomonas seymouri	52%	100%
A0A0N0P6F5	Leptomonas seymouri	72%	100%
A0A0N0P6F6	Leptomonas seymouri	26%	85%
A0A0N0P8T9	Leptomonas seymouri	26%	82%
A0A0N0P955	Leptomonas seymouri	25%	86%
A0A0N1I2L5	Leptomonas seymouri	25%	86%
A0A0N1I3F8	Leptomonas seymouri	26%	77%
A0A0N1I3H4	Leptomonas seymouri	28%	75%
A0A0N1I8K7	Leptomonas seymouri	21%	84%
A0A0N1I8W4	Leptomonas seymouri	27%	84%
A0A0N1I9T3	Leptomonas seymouri	26%	85%
A0A0N1IAJ0	Leptomonas seymouri	26%	86%
A0A0N1IJ81	Leptomonas seymouri	38%	86%
A0A0N1IMP2	Leptomonas seymouri	26%	81%
A0A0N1PA98	Leptomonas seymouri	24%	67%
A0A0N1PBP2	Leptomonas seymouri	25%	83%
A0A0N1PFD1	Leptomonas seymouri	28%	82%
A0A0S4IV32	Bodo saltans	32%	84%
A0A0S4JBX6	Bodo saltans	27%	77%
A0A0S4JCF0	Bodo saltans	24%	99%
A0A0S4JHM8	Bodo saltans	23%	86%
A0A0S4JPU4	Bodo saltans	25%	84%
A0A0S4JQ87	Bodo saltans	25%	91%
A0A0S4JU02	Bodo saltans	27%	85%
A0A1X0NJR7	Trypanosomatidae	28%	83%
A0A1X0NKS5	Trypanosomatidae	23%	86%
A0A1X0NKV2	Trypanosomatidae	28%	82%
A0A1X0NKW7	Trypanosomatidae	24%	87%
A0A1X0NLA5	Trypanosomatidae	26%	89%
A0A1X0NNX9	Trypanosomatidae	24%	91%
A0A1X0NPV3	Trypanosomatidae	28%	90%
A0A1X0NQH3	Trypanosomatidae	24%	92%
A0A1X0NR26	Trypanosomatidae	25%	89%
A0A1X0NRL3	Trypanosomatidae	29%	88%
A0A1X0NRL7	Trypanosomatidae	22%	86%
A0A1X0NYI3	Trypanosomatidae	27%	82%
A0A1X0P1N2	Trypanosomatidae	42%	89%
A0A1X0P4S1	Trypanosomatidae	54%	100%
A0A1X0P814	Trypanosomatidae	24%	84%
A0A1X0P9N8	Trypanosomatidae	26%	90%
A0A3Q8ICL1	Leishmania donovani	23%	68%
A0A3Q8ID74	Leishmania donovani	27%	100%
A0A3Q8IDG8	Leishmania donovani	24%	100%
A0A3Q8IEP8	Leishmania donovani	24%	100%
A0A3Q8IFZ0	Leishmania donovani	27%	100%
A0A3Q8IG00	Leishmania donovani	26%	100%
A0A3Q8IGE6	Leishmania donovani	23%	70%
A0A3Q8IHG8	Leishmania donovani	25%	100%
A0A3Q8IHH7	Leishmania donovani	36%	100%
A0A3Q8IJH2	Leishmania donovani	26%	100%
A0A3Q8IJX8	Leishmania donovani	23%	100%
A0A3Q8ILE0	Leishmania donovani	24%	100%
A0A3Q8IN54	Leishmania donovani	51%	100%
A0A3Q8IQG8	Leishmania donovani	25%	100%
A0A3R7JSA0	Trypanosoma rangeli	23%	86%
A0A3R7KDS3	Trypanosoma rangeli	23%	100%
A0A3R7MQD8	Trypanosoma rangeli	27%	88%
A0A3R7MWF1	Trypanosoma rangeli	44%	94%
A0A3R7N1H9	Trypanosoma rangeli	23%	84%
A0A3R7N2A2	Trypanosoma rangeli	27%	94%
A0A3R7R2W8	Trypanosoma rangeli	29%	88%
A0A3R7RFB5	Trypanosoma rangeli	24%	81%
A0A3R7RQX3	Trypanosoma rangeli	23%	86%
A0A3S5H6T4	Leishmania donovani	26%	100%
A0A3S5H7P4	Leishmania donovani	29%	100%
A0A3S5ISG3	Trypanosoma rangeli	27%	83%
A0A3S7WQ39	Leishmania donovani	26%	100%
A0A3S7X443	Leishmania donovani	25%	100%
A0A3S7X458	Leishmania donovani	25%	100%
A0A3S7X4A1	Leishmania donovani	23%	100%
A0A3S7X4L2	Leishmania donovani	23%	68%
A0A3S7X4N4	Leishmania donovani	23%	68%
A0A3S7X4P0	Leishmania donovani	23%	68%
A0A3S7XCE3	Leishmania donovani	25%	86%
A0A422MW74	Trypanosoma rangeli	21%	80%
A0A422N5W8	Trypanosoma rangeli	54%	100%
A0A422N608	Trypanosoma rangeli	23%	84%
A0A422NBM3	Trypanosoma rangeli	27%	87%
A0A422NBQ2	Trypanosoma rangeli	26%	93%
A0A422NZS1	Trypanosoma rangeli	26%	87%
A0A451EJH9	Leishmania donovani	24%	100%
A2VCW5	Rattus norvegicus	23%	86%
A2VE31	Bos taurus	22%	81%
A4H565	Leishmania braziliensis	26%	100%
A4HC75	Leishmania braziliensis	26%	100%
A4HFJ2	Leishmania braziliensis	27%	100%
A4HFT5	Leishmania braziliensis	23%	100%
A4HJ06	Leishmania braziliensis	26%	100%
A4HJ07	Leishmania braziliensis	25%	100%
A4HJ09	Leishmania braziliensis	25%	100%
A4HJ10	Leishmania braziliensis	26%	100%
A4HJ35	Leishmania braziliensis	26%	100%
A4HJ36	Leishmania braziliensis	28%	100%
A4HJ37	Leishmania braziliensis	25%	100%
A4HJ63	Leishmania braziliensis	23%	100%
A4HJF8	Leishmania braziliensis	25%	67%
A4HJF9	Leishmania braziliensis	25%	70%
A4HJG1	Leishmania braziliensis	24%	70%
A4HJG3	Leishmania braziliensis	26%	67%
A4HJG5	Leishmania braziliensis	26%	67%
A4HKQ7	Leishmania braziliensis	26%	100%
A4HLK3	Leishmania braziliensis	38%	100%
A4HNJ6	Leishmania braziliensis	81%	100%
A4HNJ7	Leishmania braziliensis	52%	100%
A4HNQ0	Leishmania braziliensis	26%	100%
A4HTE2	Leishmania infantum	26%	100%
A4HZQ0	Leishmania infantum	24%	100%
A4I2V2	Leishmania infantum	24%	69%
A4I6F1	Leishmania infantum	29%	100%
A4I6F2	Leishmania infantum	24%	100%
A4I6I1	Leishmania infantum	23%	100%
A4I6J8	Leishmania infantum	26%	100%
A4I6J9	Leishmania infantum	25%	100%
A4I6K0	Leishmania infantum	27%	100%
A4I6L3	Leishmania infantum	26%	100%
A4I6L4	Leishmania infantum	23%	100%
A4I6W4	Leishmania infantum	23%	68%
A4I887	Leishmania infantum	26%	100%
A4I914	Leishmania infantum	36%	100%
A4IC53	Leishmania infantum	100%	100%
A4IC66	Leishmania infantum	51%	99%
A4ICC3	Leishmania infantum	25%	100%
A4ICU5	Leishmania infantum	25%	100%
A6NNN8	Homo sapiens	21%	94%
A7E3U5	Bos taurus	24%	89%
A8KBL5	Danio rerio	25%	92%
C9ZMB9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	87%
C9ZMD1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	84%
C9ZMD2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	21%	87%
C9ZMD3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	22%	84%
C9ZMD4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	21%	87%
C9ZN51	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	91%
C9ZN59	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	85%
C9ZN60	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	87%
C9ZVS1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	78%
C9ZVS2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	76%
C9ZVS3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	77%
C9ZWQ7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	21%	88%
C9ZWQ8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	20%	88%
C9ZWQ9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	21%	88%
C9ZWR0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	88%
C9ZWR1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	75%
C9ZWR7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	88%
C9ZWX2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	89%
C9ZWX3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	89%
C9ZWX4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	89%
C9ZWX5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	89%
C9ZWX6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	89%
C9ZWX7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	89%
C9ZWY0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	22%	87%
D0A362	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	21%	100%
D0AAF6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	89%
D0AAF8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	89%
D0AAG7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	83%
D0AAG8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	83%
D3Z813	Rattus norvegicus	25%	91%
E8NHF9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E8NHS7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	71%
E9AD44	Leishmania major	25%	100%
E9AD45	Leishmania major	27%	100%
E9ADD7	Leishmania major	24%	100%
E9AG08	Leishmania major	93%	100%
E9AG09	Leishmania major	52%	100%
E9AHD7	Leishmania infantum	25%	100%
E9AHD9	Leishmania infantum	27%	100%
E9AHK8	Leishmania infantum	24%	100%
E9AHL1	Leishmania infantum	23%	68%
E9AHL2	Leishmania infantum	24%	100%
E9AHL3	Leishmania infantum	23%	68%
E9ALD5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9ASF9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9AUB8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9AVK6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9AYW8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9AYW9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9AZ62	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9B1I3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	99%
E9B1I4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9B1I6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9B1K7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9B1K8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	100%
E9B1K9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9B1N8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9B1N9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9B1Y0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	67%
E9B345	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9B3X9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	45%	84%
E9B761	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
E9B762	Leishmania mexicana (strain MHOM/GT/2001/U1103)	51%	100%
F4KBM7	Arabidopsis thaliana	23%	90%
G3UVW3	Mus musculus	24%	90%
O74327	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	24%	98%
P38176	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	22%	89%
P39981	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	20%	85%
P40074	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	26%	92%
Q28HE5	Xenopus tropicalis	25%	92%
Q3U1J0	Mus musculus	22%	86%
Q3USY0	Mus musculus	23%	91%
Q4Q072	Leishmania major	25%	100%
Q4Q236	Leishmania major	26%	100%
Q4Q445	Leishmania major	37%	100%
Q4Q509	Leishmania major	26%	100%
Q4Q680	Leishmania major	22%	68%
Q4Q682	Leishmania major	22%	70%
Q4Q683	Leishmania major	22%	68%
Q4Q6H5	Leishmania major	23%	100%
Q4Q6K5	Leishmania major	24%	100%
Q4Q6K6	Leishmania major	26%	100%
Q4Q6M8	Leishmania major	27%	100%
Q4Q6M9	Leishmania major	25%	100%
Q4Q6N0	Leishmania major	25%	100%
Q4Q6N1	Leishmania major	26%	100%
Q4QBX3	Leishmania major	23%	100%
Q4QIH0	Leishmania major	25%	100%
Q503G8	Danio rerio	25%	91%
Q5E9S9	Bos taurus	22%	86%
Q5EA97	Bos taurus	25%	89%
Q5F468	Gallus gallus	23%	82%
Q5HZH7	Mus musculus	23%	95%
Q5R443	Pongo abelii	20%	84%
Q5R9F5	Pongo abelii	23%	89%
Q5SPB1	Danio rerio	22%	81%
Q5XH90	Xenopus tropicalis	22%	83%
Q6DEL1	Danio rerio	21%	88%
Q6DFE7	Xenopus laevis	21%	91%
Q6JWR2	Rattus norvegicus	24%	89%
Q6WWW3	Rattus norvegicus	25%	90%
Q8BWH0	Mus musculus	24%	89%
Q8CFE6	Mus musculus	22%	81%
Q8IZM9	Homo sapiens	23%	90%
Q8K2P7	Mus musculus	20%	85%
Q8WUX1	Homo sapiens	21%	87%
Q99624	Homo sapiens	24%	81%
Q9DCP2	Mus musculus	24%	81%
Q9H2H9	Homo sapiens	20%	84%
Q9JHE5	Rattus norvegicus	22%	81%
Q9JHZ9	Rattus norvegicus	24%	81%
Q9JM15	Rattus norvegicus	22%	85%
Q9LI61	Arabidopsis thaliana	25%	89%
Q9M8L9	Arabidopsis thaliana	22%	84%
Q9NVC3	Homo sapiens	23%	89%
V5AXD0	Trypanosoma cruzi	43%	94%
V5AZP2	Trypanosoma cruzi	27%	68%
V5B9A6	Trypanosoma cruzi	27%	89%
V5BA72	Trypanosoma cruzi	27%	89%
V5BH70	Trypanosoma cruzi	23%	92%
V5BIJ1	Trypanosoma cruzi	28%	73%
V5BMG4	Trypanosoma cruzi	22%	86%
V5BTX5	Trypanosoma cruzi	54%	81%
V5D7K9	Trypanosoma cruzi	28%	91%
V5DCG4	Trypanosoma cruzi	24%	90%
V5DKR4	Trypanosoma cruzi	25%	92%