LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7XA57_LEIDO
TriTrypDb:
LdBPK_360120.1 * , LdCL_360006000 , LDHU3_36.0180
Length:
849

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 5
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 2
GO:0110165 cellular anatomical entity 1 2
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Expansion

Sequence features

A0A3S7XA57
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XA57

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 160 164 PF00656 0.464
CLV_C14_Caspase3-7 186 190 PF00656 0.481
CLV_C14_Caspase3-7 659 663 PF00656 0.637
CLV_NRD_NRD_1 106 108 PF00675 0.550
CLV_NRD_NRD_1 134 136 PF00675 0.480
CLV_NRD_NRD_1 182 184 PF00675 0.498
CLV_NRD_NRD_1 219 221 PF00675 0.459
CLV_NRD_NRD_1 340 342 PF00675 0.521
CLV_NRD_NRD_1 347 349 PF00675 0.558
CLV_NRD_NRD_1 372 374 PF00675 0.477
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1HVC9 Leptomonas seymouri 43% 100%
A4HNL8 Leishmania braziliensis 72% 100%
A4ICX6 Leishmania infantum 99% 100%
E9ASC9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 86% 100%
Q4Q267 Leishmania major 90% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS