Methyltransf_11 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3S7XA23_LEIDO

TriTrypDb:

LdBPK_355110.1 , LdCL_350056800 , LDHU3_35.6800

Length:

286

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7XA23

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XA23

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	237	241	PF00656	0.327
CLV_NRD_NRD_1	34	36	PF00675	0.670
CLV_PCSK_SKI1_1	172	176	PF00082	0.443
DEG_Nend_UBRbox_3	1	3	PF02207	0.640
DEG_SPOP_SBC_1	106	110	PF00917	0.650
DOC_MAPK_gen_1	212	222	PF00069	0.359
DOC_MAPK_JIP1_4	215	221	PF00069	0.478
DOC_MAPK_MEF2A_6	112	121	PF00069	0.468
DOC_USP7_MATH_1	105	109	PF00917	0.647
DOC_USP7_MATH_1	155	159	PF00917	0.623
DOC_WW_Pin1_4	148	153	PF00397	0.492
DOC_WW_Pin1_4	229	234	PF00397	0.448
LIG_14-3-3_CanoR_1	170	175	PF00244	0.352
LIG_14-3-3_CanoR_1	271	279	PF00244	0.412
LIG_Actin_WH2_2	200	217	PF00022	0.367
LIG_BRCT_BRCA1_1	152	156	PF00533	0.532
LIG_deltaCOP1_diTrp_1	14	19	PF00928	0.465
LIG_FAT_LD_1	96	104	PF03623	0.487
LIG_FHA_1	111	117	PF00498	0.413
LIG_FHA_1	78	84	PF00498	0.521
LIG_HCF-1_HBM_1	17	20	PF13415	0.542
LIG_LIR_Gen_1	14	20	PF02991	0.541
LIG_LIR_Nem_3	14	19	PF02991	0.545
LIG_LIR_Nem_3	270	275	PF02991	0.378
LIG_LIR_Nem_3	51	56	PF02991	0.399
LIG_PCNA_yPIPBox_3	200	212	PF02747	0.371
LIG_Pex14_1	16	20	PF04695	0.422
LIG_Pex14_1	52	56	PF04695	0.385
LIG_Pex14_2	15	19	PF04695	0.426
LIG_SH2_CRK	277	281	PF00017	0.371
LIG_SH2_NCK_1	277	281	PF00017	0.371
LIG_SH2_SRC	249	252	PF00017	0.332
LIG_SH2_STAP1	249	253	PF00017	0.444
LIG_SH2_STAP1	277	281	PF00017	0.489
LIG_SH2_STAP1	50	54	PF00017	0.383
LIG_SH2_STAP1	59	63	PF00017	0.375
LIG_SH2_STAT5	206	209	PF00017	0.290
LIG_SH2_STAT5	234	237	PF00017	0.372
LIG_SH3_3	149	155	PF00018	0.635
LIG_SH3_3	210	216	PF00018	0.397
LIG_SH3_3	227	233	PF00018	0.401
LIG_SUMO_SIM_anti_2	177	184	PF11976	0.361
LIG_SUMO_SIM_par_1	221	229	PF11976	0.500
LIG_TYR_ITIM	247	252	PF00017	0.508
LIG_WRC_WIRS_1	192	197	PF05994	0.526
LIG_WRC_WIRS_1	242	247	PF05994	0.502
MOD_CK1_1	108	114	PF00069	0.632
MOD_CK1_1	150	156	PF00069	0.579
MOD_CK1_1	164	170	PF00069	0.322
MOD_CK1_1	224	230	PF00069	0.520
MOD_CK1_1	270	276	PF00069	0.478
MOD_GlcNHglycan	236	239	PF01048	0.415
MOD_GlcNHglycan	281	284	PF01048	0.465
MOD_GSK3_1	106	113	PF00069	0.630
MOD_GSK3_1	146	153	PF00069	0.510
MOD_GSK3_1	170	177	PF00069	0.341
MOD_LATS_1	262	268	PF00433	0.572
MOD_NEK2_1	146	151	PF00069	0.417
MOD_NEK2_1	191	196	PF00069	0.504
MOD_NEK2_1	221	226	PF00069	0.480
MOD_PKA_2	270	276	PF00069	0.427
MOD_PKA_2	42	48	PF00069	0.446
MOD_Plk_4	42	48	PF00069	0.451
MOD_Plk_4	69	75	PF00069	0.503
MOD_ProDKin_1	148	154	PF00069	0.500
MOD_ProDKin_1	229	235	PF00069	0.442
TRG_DiLeu_BaEn_1	42	47	PF01217	0.430
TRG_ENDOCYTIC_2	249	252	PF00928	0.507
TRG_ENDOCYTIC_2	277	280	PF00928	0.359
TRG_ENDOCYTIC_2	50	53	PF00928	0.387
TRG_ER_diArg_1	169	172	PF00400	0.453
TRG_Pf-PMV_PEXEL_1	261	266	PF00026	0.436
TRG_Pf-PMV_PEXEL_1	38	42	PF00026	0.490

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HTH2	Leptomonas seymouri	63%	100%
A4HNH6	Leishmania braziliensis	77%	100%
A4IC32	Leishmania infantum	99%	100%
E9AFY7	Leishmania major	92%	100%
E9B740	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%