Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7XA03_LEIDO

TriTrypDb:

LdBPK_354820.1 , LdCL_350053200 , LDHU3_35.6340

Length:

148


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	8
GO:0110165	cellular anatomical entity	1	8
GO:0005634	nucleus	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1

A0A3S7XA03

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7XA03


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	50	52	PF00675	0.390
CLV_PCSK_KEX2_1	50	52	PF00082	0.389
DEG_Nend_UBRbox_2	1	3	PF02207	0.415
DOC_MAPK_MEF2A_6	75	82	PF00069	0.357
DOC_PP2B_PxIxI_1	59	65	PF00149	0.479
LIG_14-3-3_CanoR_1	108	114	PF00244	0.597
LIG_FHA_1	133	139	PF00498	0.381
LIG_FHA_2	124	130	PF00498	0.536
LIG_LIR_Gen_1	12	22	PF02991	0.303
LIG_LIR_LC3C_4	76	79	PF02991	0.306
LIG_LIR_Nem_3	57	62	PF02991	0.623
LIG_LYPXL_yS_3	59	62	PF13949	0.597
LIG_PDZ_Class_2	143	148	PF00595	0.354
LIG_PTB_Apo_2	3	10	PF02174	0.439
LIG_PTB_Phospho_1	3	9	PF10480	0.438
LIG_SH2_NCK_1	128	132	PF00017	0.297
LIG_SH2_STAP1	128	132	PF00017	0.297
LIG_SH2_STAT3	92	95	PF00017	0.350
LIG_SH2_STAT5	15	18	PF00017	0.404
LIG_SH2_STAT5	42	45	PF00017	0.556
LIG_SUMO_SIM_anti_2	76	81	PF11976	0.355
LIG_SUMO_SIM_par_1	76	81	PF11976	0.453
LIG_TYR_ITSM	55	62	PF00017	0.609
MOD_CK1_1	65	71	PF00069	0.355
MOD_CK2_1	123	129	PF00069	0.547
MOD_GlcNHglycan	18	21	PF01048	0.430
MOD_GlcNHglycan	64	67	PF01048	0.384
MOD_GlcNHglycan	95	98	PF01048	0.355
MOD_GSK3_1	65	72	PF00069	0.355
MOD_N-GLC_1	86	91	PF02516	0.528
MOD_NEK2_1	16	21	PF00069	0.440
MOD_NEK2_1	69	74	PF00069	0.355
MOD_Plk_1	86	92	PF00069	0.330
MOD_Plk_4	4	10	PF00069	0.374
MOD_Plk_4	69	75	PF00069	0.319
MOD_Plk_4	78	84	PF00069	0.376
MOD_Plk_4	87	93	PF00069	0.286
TRG_ENDOCYTIC_2	15	18	PF00928	0.425
TRG_ENDOCYTIC_2	59	62	PF00928	0.599
TRG_ER_diArg_1	49	51	PF00400	0.597
TRG_ER_diLys_1	144	148	PF00400	0.386


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I454	Leptomonas seymouri	59%	100%
A0A0S4J9A3	Bodo saltans	36%	97%
A0A1X0P5Z3	Trypanosomatidae	39%	98%
A0A422P158	Trypanosoma rangeli	39%	100%
A4HNE0	Leishmania braziliensis	87%	100%
A4IC13	Leishmania infantum	100%	100%
C9ZYI9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	97%
E9B704	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
Q9N6L8	Leishmania major	98%	100%