Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3S7X9Z1_LEIDO

TriTrypDb:

LdBPK_354840.1 , LdCL_350053400 , LDHU3_35.6360

Length:

162

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X9Z1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X9Z1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	144	148	PF00082	0.659
DEG_SPOP_SBC_1	135	139	PF00917	0.649
DOC_CYCLIN_yCln2_LP_2	120	123	PF00134	0.566
DOC_PP2B_LxvP_1	108	111	PF13499	0.542
DOC_PP2B_LxvP_1	120	123	PF13499	0.566
DOC_USP7_MATH_1	135	139	PF00917	0.649
DOC_USP7_MATH_1	44	48	PF00917	0.573
DOC_USP7_MATH_1	51	55	PF00917	0.521
DOC_WW_Pin1_4	144	149	PF00397	0.642
LIG_14-3-3_CanoR_1	124	130	PF00244	0.559
LIG_14-3-3_CanoR_1	13	20	PF00244	0.661
LIG_14-3-3_CanoR_1	82	86	PF00244	0.524
LIG_BIR_II_1	1	5	PF00653	0.633
LIG_FHA_1	103	109	PF00498	0.393
LIG_FHA_1	155	161	PF00498	0.589
LIG_FHA_1	24	30	PF00498	0.645
LIG_FHA_1	48	54	PF00498	0.623
LIG_FHA_1	85	91	PF00498	0.526
LIG_LIR_Gen_1	105	115	PF02991	0.537
LIG_LIR_Gen_1	49	60	PF02991	0.577
LIG_LIR_Nem_3	105	110	PF02991	0.539
LIG_LIR_Nem_3	147	153	PF02991	0.592
LIG_LIR_Nem_3	49	55	PF02991	0.584
LIG_SH2_STAP1	31	35	PF00017	0.564
LIG_SH3_3	145	151	PF00018	0.683
LIG_WRC_WIRS_1	6	11	PF05994	0.623
LIG_WW_3	121	125	PF00397	0.566
MOD_CK1_1	2	8	PF00069	0.646
MOD_CK1_1	42	48	PF00069	0.666
MOD_CK2_1	13	19	PF00069	0.628
MOD_GlcNHglycan	141	144	PF01048	0.590
MOD_GlcNHglycan	15	18	PF01048	0.714
MOD_GlcNHglycan	157	160	PF01048	0.587
MOD_GlcNHglycan	76	79	PF01048	0.591
MOD_GlcNHglycan	97	100	PF01048	0.608
MOD_GSK3_1	1	8	PF00069	0.670
MOD_GSK3_1	135	142	PF00069	0.596
MOD_GSK3_1	18	25	PF00069	0.519
MOD_GSK3_1	35	42	PF00069	0.541
MOD_GSK3_1	43	50	PF00069	0.560
MOD_GSK3_1	65	72	PF00069	0.559
MOD_GSK3_1	81	88	PF00069	0.390
MOD_GSK3_1	9	16	PF00069	0.595
MOD_NEK2_1	1	6	PF00069	0.680
MOD_NEK2_1	136	141	PF00069	0.572
MOD_NEK2_1	154	159	PF00069	0.435
MOD_NEK2_1	85	90	PF00069	0.542
MOD_NEK2_1	9	14	PF00069	0.601
MOD_PKA_2	81	87	PF00069	0.527
MOD_Plk_4	102	108	PF00069	0.552
MOD_Plk_4	2	8	PF00069	0.630
MOD_Plk_4	51	57	PF00069	0.516
MOD_Plk_4	69	75	PF00069	0.404
MOD_Plk_4	81	87	PF00069	0.422
MOD_ProDKin_1	144	150	PF00069	0.639
TRG_DiLeu_BaLyEn_6	108	113	PF01217	0.535

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4IC15	Leishmania infantum	100%	100%
E9B706	Leishmania mexicana (strain MHOM/GT/2001/U1103)	71%	100%