Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7X9X7_LEIDO

TriTrypDb:

LdBPK_354510.1 , LdCL_350050200 , LDHU3_35.5940

Length:

238

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X9X7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X9X7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	230	234	PF00656	0.471
CLV_C14_Caspase3-7	4	8	PF00656	0.553
CLV_NRD_NRD_1	202	204	PF00675	0.393
CLV_PCSK_KEX2_1	202	204	PF00082	0.393
CLV_PCSK_SKI1_1	24	28	PF00082	0.396
DEG_APCC_DBOX_1	202	210	PF00400	0.412
DEG_APCC_DBOX_1	221	229	PF00400	0.275
DEG_Nend_UBRbox_3	1	3	PF02207	0.661
DOC_ANK_TNKS_1	166	173	PF00023	0.437
DOC_CYCLIN_RxL_1	21	29	PF00134	0.423
DOC_PP1_RVXF_1	22	28	PF00149	0.439
DOC_PP4_FxxP_1	178	181	PF00568	0.521
DOC_PP4_FxxP_1	27	30	PF00568	0.511
DOC_USP7_MATH_1	113	117	PF00917	0.644
DOC_USP7_MATH_1	51	55	PF00917	0.597
DOC_USP7_MATH_1	6	10	PF00917	0.514
DOC_USP7_MATH_1	89	93	PF00917	0.616
DOC_USP7_MATH_2	42	48	PF00917	0.515
DOC_WW_Pin1_4	173	178	PF00397	0.511
DOC_WW_Pin1_4	2	7	PF00397	0.560
DOC_WW_Pin1_4	26	31	PF00397	0.541
LIG_14-3-3_CanoR_1	122	131	PF00244	0.559
LIG_14-3-3_CanoR_1	24	30	PF00244	0.452
LIG_14-3-3_CanoR_1	45	51	PF00244	0.612
LIG_AP2alpha_1	231	235	PF02296	0.479
LIG_APCC_ABBA_1	175	180	PF00400	0.489
LIG_BRCT_BRCA1_1	231	235	PF00533	0.398
LIG_EH_1	40	44	PF12763	0.548
LIG_eIF4E_1	93	99	PF01652	0.486
LIG_FHA_1	126	132	PF00498	0.586
LIG_FHA_1	147	153	PF00498	0.598
LIG_FHA_1	193	199	PF00498	0.438
LIG_LIR_Apic_2	176	181	PF02991	0.522
LIG_Pex14_2	231	235	PF04695	0.479
LIG_Pex14_2	99	103	PF04695	0.449
LIG_SH2_CRK	104	108	PF00017	0.451
LIG_SH2_STAP1	104	108	PF00017	0.451
LIG_WRC_WIRS_1	228	233	PF05994	0.456
MOD_CK1_1	116	122	PF00069	0.670
MOD_CK1_1	125	131	PF00069	0.616
MOD_CK1_1	192	198	PF00069	0.453
MOD_CK1_1	227	233	PF00069	0.517
MOD_CK1_1	29	35	PF00069	0.531
MOD_CK1_1	74	80	PF00069	0.702
MOD_CK2_1	29	35	PF00069	0.556
MOD_CK2_1	8	14	PF00069	0.450
MOD_GlcNHglycan	10	13	PF01048	0.503
MOD_GlcNHglycan	118	121	PF01048	0.643
MOD_GlcNHglycan	58	61	PF01048	0.570
MOD_GlcNHglycan	76	79	PF01048	0.610
MOD_GSK3_1	112	119	PF00069	0.695
MOD_GSK3_1	122	129	PF00069	0.579
MOD_GSK3_1	2	9	PF00069	0.574
MOD_GSK3_1	227	234	PF00069	0.453
MOD_GSK3_1	25	32	PF00069	0.545
MOD_GSK3_1	74	81	PF00069	0.726
MOD_N-GLC_1	1	6	PF02516	0.586
MOD_N-GLC_1	7	12	PF02516	0.456
MOD_NEK2_1	1	6	PF00069	0.662
MOD_NEK2_1	107	112	PF00069	0.511
MOD_NEK2_1	123	128	PF00069	0.562
MOD_NEK2_1	131	136	PF00069	0.518
MOD_NEK2_1	215	220	PF00069	0.393
MOD_NEK2_1	231	236	PF00069	0.481
MOD_NEK2_1	25	30	PF00069	0.503
MOD_PIKK_1	107	113	PF00454	0.475
MOD_PIKK_1	131	137	PF00454	0.593
MOD_PKA_2	126	132	PF00069	0.688
MOD_PKA_2	146	152	PF00069	0.566
MOD_PKA_2	44	50	PF00069	0.621
MOD_PKA_2	71	77	PF00069	0.582
MOD_PKB_1	151	159	PF00069	0.478
MOD_Plk_1	192	198	PF00069	0.391
MOD_Plk_1	34	40	PF00069	0.608
MOD_Plk_4	127	133	PF00069	0.649
MOD_Plk_4	29	35	PF00069	0.515
MOD_ProDKin_1	173	179	PF00069	0.506
MOD_ProDKin_1	2	8	PF00069	0.554
MOD_ProDKin_1	26	32	PF00069	0.546
MOD_SUMO_for_1	181	184	PF00179	0.486
MOD_SUMO_rev_2	176	183	PF00179	0.456
TRG_DiLeu_BaEn_1	21	26	PF01217	0.423
TRG_DiLeu_BaEn_2	192	198	PF01217	0.432
TRG_DiLeu_BaLyEn_6	103	108	PF01217	0.453
TRG_DiLeu_LyEn_5	21	26	PF01217	0.423
TRG_ENDOCYTIC_2	104	107	PF00928	0.397
TRG_ER_diArg_1	201	203	PF00400	0.369
TRG_ER_diArg_1	22	25	PF00400	0.429
TRG_NES_CRM1_1	189	200	PF08389	0.311
TRG_Pf-PMV_PEXEL_1	106	111	PF00026	0.598

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFH5	Leptomonas seymouri	46%	100%
A0A3R7L7B9	Trypanosoma rangeli	26%	100%
C9ZYM1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	100%