Elongation factor 1-alpha, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

elongation factor 1-alpha, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X9T0_LEIDO

TriTrypDb:

LdBPK_354220.1 , LdCL_350047300 , LDHU3_35.5440

Length:

646

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3S7X9T0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X9T0

Function

Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	1
GO:0006414	translational elongation	5	1
GO:0006518	peptide metabolic process	4	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009058	biosynthetic process	2	1
GO:0009059	macromolecule biosynthetic process	4	1
GO:0009987	cellular process	1	1
GO:0019538	protein metabolic process	3	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	1
GO:0043043	peptide biosynthetic process	5	1
GO:0043170	macromolecule metabolic process	3	1
GO:0043603	amide metabolic process	3	1
GO:0043604	amide biosynthetic process	4	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044249	cellular biosynthetic process	3	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0044271	cellular nitrogen compound biosynthetic process	4	1
GO:0071704	organic substance metabolic process	2	1
GO:1901564	organonitrogen compound metabolic process	3	1
GO:1901566	organonitrogen compound biosynthetic process	4	1
GO:1901576	organic substance biosynthetic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	11
GO:0003676	nucleic acid binding	3	10
GO:0003746	translation elongation factor activity	4	10
GO:0003824	catalytic activity	1	11
GO:0003924	GTPase activity	7	11
GO:0005488	binding	1	11
GO:0005525	GTP binding	5	11
GO:0008135	translation factor activity, RNA binding	3	10
GO:0016462	pyrophosphatase activity	5	11
GO:0016787	hydrolase activity	2	11
GO:0016817	hydrolase activity, acting on acid anhydrides	3	11
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	11
GO:0017076	purine nucleotide binding	4	11
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	11
GO:0019001	guanyl nucleotide binding	5	11
GO:0032553	ribonucleotide binding	3	11
GO:0032555	purine ribonucleotide binding	4	11
GO:0032561	guanyl ribonucleotide binding	5	11
GO:0035639	purine ribonucleoside triphosphate binding	4	11
GO:0036094	small molecule binding	2	11
GO:0043167	ion binding	2	11
GO:0043168	anion binding	3	11
GO:0045182	translation regulator activity	1	10
GO:0090079	translation regulator activity, nucleic acid binding	2	10
GO:0097159	organic cyclic compound binding	2	11
GO:0097367	carbohydrate derivative binding	2	11
GO:1901265	nucleoside phosphate binding	3	11
GO:1901363	heterocyclic compound binding	2	11

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	179	183	PF00656	0.560
CLV_C14_Caspase3-7	326	330	PF00656	0.445
CLV_C14_Caspase3-7	578	582	PF00656	0.507
CLV_MEL_PAP_1	249	255	PF00089	0.268
CLV_NRD_NRD_1	210	212	PF00675	0.576
CLV_NRD_NRD_1	268	270	PF00675	0.173
CLV_NRD_NRD_1	287	289	PF00675	0.212
CLV_NRD_NRD_1	304	306	PF00675	0.212
CLV_PCSK_FUR_1	144	148	PF00082	0.619
CLV_PCSK_KEX2_1	139	141	PF00082	0.488
CLV_PCSK_KEX2_1	146	148	PF00082	0.581
CLV_PCSK_KEX2_1	210	212	PF00082	0.595
CLV_PCSK_KEX2_1	286	288	PF00082	0.245
CLV_PCSK_KEX2_1	304	306	PF00082	0.232
CLV_PCSK_PC1ET2_1	139	141	PF00082	0.541
CLV_PCSK_PC1ET2_1	146	148	PF00082	0.632
CLV_PCSK_SKI1_1	213	217	PF00082	0.569
CLV_PCSK_SKI1_1	288	292	PF00082	0.212
CLV_PCSK_SKI1_1	420	424	PF00082	0.312
CLV_PCSK_SKI1_1	471	475	PF00082	0.318
CLV_PCSK_SKI1_1	548	552	PF00082	0.267
CLV_PCSK_SKI1_1	624	628	PF00082	0.212
DEG_APCC_DBOX_1	451	459	PF00400	0.353
DEG_Nend_UBRbox_3	1	3	PF02207	0.499
DOC_CYCLIN_RxL_1	445	457	PF00134	0.335
DOC_CYCLIN_yCln2_LP_2	447	453	PF00134	0.322
DOC_MAPK_gen_1	144	154	PF00069	0.591
DOC_MAPK_gen_1	286	292	PF00069	0.437
DOC_MAPK_JIP1_4	449	455	PF00069	0.251
DOC_PP2B_LxvP_1	309	312	PF13499	0.412
DOC_USP7_MATH_1	188	192	PF00917	0.683
DOC_USP7_MATH_1	237	241	PF00917	0.423
DOC_USP7_MATH_1	337	341	PF00917	0.426
DOC_USP7_MATH_1	441	445	PF00917	0.400
DOC_USP7_MATH_1	46	50	PF00917	0.770
DOC_USP7_MATH_1	488	492	PF00917	0.390
DOC_USP7_MATH_1	556	560	PF00917	0.491
DOC_USP7_MATH_1	56	60	PF00917	0.670
DOC_USP7_MATH_1	65	69	PF00917	0.477
DOC_USP7_UBL2_3	270	274	PF12436	0.429
DOC_USP7_UBL2_3	490	494	PF12436	0.373
DOC_USP7_UBL2_3	579	583	PF12436	0.437
DOC_USP7_UBL2_3	589	593	PF12436	0.407
DOC_WW_Pin1_4	169	174	PF00397	0.614
DOC_WW_Pin1_4	186	191	PF00397	0.666
DOC_WW_Pin1_4	422	427	PF00397	0.412
DOC_WW_Pin1_4	606	611	PF00397	0.493
DOC_WW_Pin1_4	79	84	PF00397	0.558
LIG_14-3-3_CanoR_1	123	131	PF00244	0.438
LIG_14-3-3_CanoR_1	163	168	PF00244	0.597
LIG_14-3-3_CanoR_1	196	202	PF00244	0.647
LIG_14-3-3_CanoR_1	452	456	PF00244	0.297
LIG_Actin_WH2_2	439	454	PF00022	0.319
LIG_BIR_III_4	310	314	PF00653	0.412
LIG_BRCT_BRCA1_1	293	297	PF00533	0.417
LIG_BRCT_BRCA1_1	536	540	PF00533	0.412
LIG_eIF4E_1	428	434	PF01652	0.426
LIG_FHA_1	196	202	PF00498	0.638
LIG_FHA_1	226	232	PF00498	0.256
LIG_FHA_1	357	363	PF00498	0.444
LIG_FHA_1	549	555	PF00498	0.455
LIG_FHA_1	559	565	PF00498	0.386
LIG_FHA_1	566	572	PF00498	0.354
LIG_FHA_1	638	644	PF00498	0.459
LIG_FHA_2	324	330	PF00498	0.440
LIG_FHA_2	536	542	PF00498	0.443
LIG_GBD_Chelix_1	385	393	PF00786	0.226
LIG_IBAR_NPY_1	76	78	PF08397	0.578
LIG_LIR_Gen_1	130	138	PF02991	0.408
LIG_LIR_Gen_1	272	279	PF02991	0.430
LIG_LIR_Gen_1	380	389	PF02991	0.412
LIG_LIR_Gen_1	425	436	PF02991	0.427
LIG_LIR_Gen_1	461	472	PF02991	0.325
LIG_LIR_Gen_1	559	567	PF02991	0.458
LIG_LIR_Gen_1	86	97	PF02991	0.394
LIG_LIR_Nem_3	130	136	PF02991	0.400
LIG_LIR_Nem_3	165	170	PF02991	0.524
LIG_LIR_Nem_3	272	278	PF02991	0.430
LIG_LIR_Nem_3	380	385	PF02991	0.435
LIG_LIR_Nem_3	425	431	PF02991	0.427
LIG_LIR_Nem_3	461	467	PF02991	0.331
LIG_LIR_Nem_3	546	550	PF02991	0.430
LIG_LIR_Nem_3	559	563	PF02991	0.412
LIG_LIR_Nem_3	86	92	PF02991	0.385
LIG_NRBOX	242	248	PF00104	0.426
LIG_NRBOX	388	394	PF00104	0.410
LIG_Pex14_2	273	277	PF04695	0.398
LIG_SH2_CRK	382	386	PF00017	0.443
LIG_SH2_CRK	78	82	PF00017	0.577
LIG_SH2_NCK_1	39	43	PF00017	0.639
LIG_SH2_NCK_1	464	468	PF00017	0.445
LIG_SH2_NCK_1	78	82	PF00017	0.502
LIG_SH2_NCK_1	8	12	PF00017	0.597
LIG_SH2_SRC	382	385	PF00017	0.443
LIG_SH2_SRC	39	42	PF00017	0.711
LIG_SH2_SRC	8	11	PF00017	0.597
LIG_SH2_STAP1	275	279	PF00017	0.426
LIG_SH2_STAP1	29	33	PF00017	0.622
LIG_SH2_STAP1	382	386	PF00017	0.426
LIG_SH2_STAP1	39	43	PF00017	0.718
LIG_SH2_STAP1	44	48	PF00017	0.739
LIG_SH2_STAP1	8	12	PF00017	0.574
LIG_SH2_STAT5	384	387	PF00017	0.451
LIG_SH2_STAT5	78	81	PF00017	0.627
LIG_SH3_3	167	173	PF00018	0.631
LIG_SH3_3	49	55	PF00018	0.551
LIG_SH3_3	494	500	PF00018	0.530
LIG_SH3_3	640	646	PF00018	0.498
LIG_Sin3_3	330	337	PF02671	0.412
LIG_SUMO_SIM_anti_2	352	359	PF11976	0.427
LIG_SUMO_SIM_anti_2	430	435	PF11976	0.499
LIG_SUMO_SIM_par_1	331	336	PF11976	0.426
LIG_SUMO_SIM_par_1	352	359	PF11976	0.476
LIG_SUMO_SIM_par_1	508	514	PF11976	0.325
LIG_SUMO_SIM_par_1	572	578	PF11976	0.406
LIG_SUMO_SIM_par_1	608	614	PF11976	0.507
LIG_TYR_ITSM	460	467	PF00017	0.453
LIG_UBA3_1	215	222	PF00899	0.584
LIG_UBA3_1	354	358	PF00899	0.243
LIG_UBA3_1	433	439	PF00899	0.354
LIG_UBA3_1	576	583	PF00899	0.360
LIG_UBA3_1	95	104	PF00899	0.441
LIG_Vh1_VBS_1	562	580	PF01044	0.290
LIG_WRC_WIRS_1	544	549	PF05994	0.266
MOD_CK1_1	106	112	PF00069	0.434
MOD_CK1_1	191	197	PF00069	0.672
MOD_CK1_1	204	210	PF00069	0.665
MOD_CK1_1	320	326	PF00069	0.318
MOD_CK1_1	513	519	PF00069	0.418
MOD_CK1_1	59	65	PF00069	0.663
MOD_CK2_1	111	117	PF00069	0.466
MOD_CK2_1	178	184	PF00069	0.751
MOD_CK2_1	337	343	PF00069	0.294
MOD_CK2_1	429	435	PF00069	0.312
MOD_CK2_1	535	541	PF00069	0.325
MOD_DYRK1A_RPxSP_1	606	610	PF00069	0.360
MOD_GlcNHglycan	105	108	PF01048	0.547
MOD_GlcNHglycan	186	189	PF01048	0.706
MOD_GlcNHglycan	190	193	PF01048	0.659
MOD_GlcNHglycan	293	296	PF01048	0.290
MOD_GlcNHglycan	323	326	PF01048	0.264
MOD_GlcNHglycan	409	412	PF01048	0.287
MOD_GlcNHglycan	468	471	PF01048	0.321
MOD_GlcNHglycan	48	51	PF01048	0.730
MOD_GlcNHglycan	67	70	PF01048	0.479
MOD_GSK3_1	184	191	PF00069	0.620
MOD_GSK3_1	197	204	PF00069	0.556
MOD_GSK3_1	205	212	PF00069	0.612
MOD_GSK3_1	317	324	PF00069	0.268
MOD_GSK3_1	333	340	PF00069	0.228
MOD_GSK3_1	510	517	PF00069	0.436
MOD_GSK3_1	546	553	PF00069	0.256
MOD_GSK3_1	581	588	PF00069	0.389
MOD_GSK3_1	59	66	PF00069	0.610
MOD_N-GLC_1	415	420	PF02516	0.312
MOD_N-GLC_1	514	519	PF02516	0.358
MOD_N-GLC_1	585	590	PF02516	0.267
MOD_NEK2_1	152	157	PF00069	0.626
MOD_NEK2_1	201	206	PF00069	0.590
MOD_NEK2_1	317	322	PF00069	0.296
MOD_NEK2_1	333	338	PF00069	0.294
MOD_NEK2_1	393	398	PF00069	0.466
MOD_NEK2_1	451	456	PF00069	0.306
MOD_NEK2_1	533	538	PF00069	0.308
MOD_NEK2_1	550	555	PF00069	0.163
MOD_NEK2_1	58	63	PF00069	0.590
MOD_PIKK_1	205	211	PF00454	0.686
MOD_PIKK_1	323	329	PF00454	0.283
MOD_PIKK_1	375	381	PF00454	0.350
MOD_PIKK_1	415	421	PF00454	0.325
MOD_PKA_1	269	275	PF00069	0.295
MOD_PKA_2	122	128	PF00069	0.446
MOD_PKA_2	162	168	PF00069	0.766
MOD_PKA_2	195	201	PF00069	0.673
MOD_PKA_2	209	215	PF00069	0.540
MOD_PKA_2	251	257	PF00069	0.325
MOD_PKA_2	451	457	PF00069	0.302
MOD_PKB_1	286	294	PF00069	0.247
MOD_Plk_1	225	231	PF00069	0.259
MOD_Plk_1	429	435	PF00069	0.294
MOD_Plk_1	514	520	PF00069	0.395
MOD_Plk_2-3	178	184	PF00069	0.616
MOD_Plk_4	106	112	PF00069	0.506
MOD_Plk_4	225	231	PF00069	0.247
MOD_Plk_4	317	323	PF00069	0.351
MOD_Plk_4	361	367	PF00069	0.380
MOD_Plk_4	429	435	PF00069	0.266
MOD_Plk_4	459	465	PF00069	0.409
MOD_Plk_4	550	556	PF00069	0.267
MOD_ProDKin_1	169	175	PF00069	0.613
MOD_ProDKin_1	186	192	PF00069	0.666
MOD_ProDKin_1	422	428	PF00069	0.247
MOD_ProDKin_1	606	612	PF00069	0.360
MOD_ProDKin_1	79	85	PF00069	0.559
MOD_SUMO_for_1	465	468	PF00179	0.439
MOD_SUMO_rev_2	578	584	PF00179	0.364
TRG_AP2beta_CARGO_1	130	140	PF09066	0.411
TRG_DiLeu_BaEn_1	388	393	PF01217	0.247
TRG_DiLeu_BaEn_1	529	534	PF01217	0.407
TRG_DiLeu_BaLyEn_6	442	447	PF01217	0.333
TRG_ENDOCYTIC_2	275	278	PF00928	0.266
TRG_ENDOCYTIC_2	382	385	PF00928	0.295
TRG_ENDOCYTIC_2	428	431	PF00928	0.268
TRG_ENDOCYTIC_2	464	467	PF00928	0.446
TRG_ENDOCYTIC_2	78	81	PF00928	0.517
TRG_ENDOCYTIC_2	8	11	PF00928	0.483
TRG_ENDOCYTIC_2	89	92	PF00928	0.327
TRG_ER_diArg_1	286	288	PF00400	0.247
TRG_ER_diArg_1	304	306	PF00400	0.247
TRG_ER_FFAT_1	34	45	PF00635	0.474

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5B5	Leptomonas seymouri	72%	100%
A0A0N1PAZ5	Leptomonas seymouri	32%	85%
A0A0S4IUT7	Bodo saltans	35%	100%
A0A0S4IX91	Bodo saltans	33%	96%
A0A0S4JRG2	Bodo saltans	34%	100%
A0A1X0NXE4	Trypanosomatidae	36%	100%
A0A1X0P591	Trypanosomatidae	58%	97%
A0A3Q8ICH2	Leishmania donovani	30%	86%
A0A3R7MLL0	Trypanosoma rangeli	33%	98%
A0A422NK97	Trypanosoma rangeli	53%	98%
A0KP35	Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049)	26%	100%
A0RUM4	Cenarchaeum symbiosum (strain A)	33%	100%
A1AEU5	Escherichia coli O1:K1 / APEC	26%	100%
A1JJT0	Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)	24%	100%
A1RRJ3	Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)	36%	100%
A1RXW9	Thermofilum pendens (strain DSM 2475 / Hrk 5)	35%	100%
A2BN41	Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5)	35%	100%
A2Q0Z0	Equus caballus	34%	100%
A3DMQ1	Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1)	34%	100%
A3MV69	Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1)	36%	100%
A4H6P3	Leishmania braziliensis	32%	100%
A4H8V4	Leishmania braziliensis	34%	100%
A4HN87	Leishmania braziliensis	83%	100%
A4HV24	Leishmania infantum	32%	85%
A4HX73	Leishmania infantum	34%	100%
A4IBV5	Leishmania infantum	100%	100%
A4WKK8	Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321 / PZ6)	36%	100%
A4YCR6	Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)	32%	100%
A5DPE3	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	33%	100%
A7FLY2	Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)	26%	100%
A7MJ69	Cronobacter sakazakii (strain ATCC BAA-894)	26%	100%
A7ZQJ5	Escherichia coli O139:H28 (strain E24377A / ETEC)	26%	100%
A8A3N0	Escherichia coli O9:H4 (strain HS)	26%	100%
A8ABM5	Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125)	37%	100%
A8ANW5	Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)	25%	100%
A9MF24	Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)	26%	100%
A9N2D8	Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)	26%	100%
A9W4X1	Methylorubrum extorquens (strain PA1)	27%	100%
B1IUS8	Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks)	26%	100%
B1LQ72	Escherichia coli (strain SMS-3-5 / SECEC)	26%	100%
B1XCS7	Escherichia coli (strain K12 / DH10B)	26%	100%
B1Z7C0	Methylorubrum populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001)	27%	100%
B2TZI0	Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)	26%	100%
B2VG01	Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99)	24%	100%
B4T461	Salmonella newport (strain SL254)	26%	100%
B4TFX1	Salmonella heidelberg (strain SL476)	26%	100%
B4TTW5	Salmonella schwarzengrund (strain CVM19633)	26%	100%
B5BEY8	Salmonella paratyphi A (strain AKU_12601)	26%	100%
B5F415	Salmonella agona (strain SL483)	26%	100%
B5FTS9	Salmonella dublin (strain CT_02021853)	26%	100%
B5QW22	Salmonella enteritidis PT4 (strain P125109)	26%	100%
B5RDQ7	Salmonella gallinarum (strain 287/91 / NCTC 13346)	26%	100%
B5Z3B3	Escherichia coli O157:H7 (strain EC4115 / EHEC)	26%	100%
B6I6E1	Escherichia coli (strain SE11)	26%	100%
B7L0X9	Methylorubrum extorquens (strain CM4 / NCIMB 13688)	26%	100%
B7LEG9	Escherichia coli (strain 55989 / EAEC)	26%	100%
B7LXG3	Escherichia coli O8 (strain IAI1)	26%	100%
B7MKM5	Escherichia coli O45:K1 (strain S88 / ExPEC)	26%	100%
B7MZ52	Escherichia coli O81 (strain ED1a)	26%	100%
B7NT95	Escherichia coli O7:K1 (strain IAI39 / ExPEC)	26%	100%
B7UHH0	Escherichia coli O127:H6 (strain E2348/69 / EPEC)	26%	100%
B7VKY2	Vibrio atlanticus (strain LGP32)	26%	100%
B8D7V3	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain Tuc7)	24%	100%
B8D9K1	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain 5A)	24%	100%
B9JB95	Agrobacterium radiobacter (strain K84 / ATCC BAA-868)	26%	100%
C0PXB1	Salmonella paratyphi C (strain RKS4594)	26%	100%
C4ZZQ5	Escherichia coli (strain K12 / MC4100 / BW2952)	26%	100%
C9ZYQ4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	54%	100%
D0A1M7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
D0A1M9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	100%
D0A7C5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	93%
E9AFP2	Leishmania major	92%	100%
E9AGP5	Leishmania infantum	34%	100%
E9AGP7	Leishmania infantum	32%	100%
E9ANQ6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	84%
E9ARD0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
E9B6U5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
O13354	Candida albicans	34%	90%
O24534	Vicia faba	34%	100%
O33581	Rhizobium tropici	27%	100%
O42820	Schizophyllum commune	33%	100%
O49169	Manihot esculenta	34%	100%
O50274	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	26%	100%
O59949	Yarrowia lipolytica (strain CLIB 122 / E 150)	34%	100%
O64937	Oryza sativa subsp. japonica	35%	100%
O74718	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	98%
O74774	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	33%	100%
P02993	Artemia salina	33%	100%
P02994	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	100%
P05303	Drosophila melanogaster	35%	100%
P05453	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	94%
P06805	Mucor circinelloides f. lusitanicus	33%	100%
P08736	Drosophila melanogaster	33%	100%
P0CN30	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	34%	100%
P0CN31	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	34%	100%
P0CT31	Dictyostelium discoideum	36%	100%
P0CT32	Dictyostelium discoideum	36%	100%
P0CT53	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	33%	100%
P0CT54	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	33%	100%
P0CT55	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	33%	100%
P0CY35	Candida albicans (strain SC5314 / ATCC MYA-2876)	33%	100%
P0DH99	Arabidopsis thaliana	34%	100%
P10126	Mus musculus	34%	100%
P13442	Rhizobium meliloti (strain 1021)	27%	100%
P13549	Xenopus laevis	34%	100%
P14864	Mucor circinelloides f. lusitanicus	33%	100%
P14865	Mucor circinelloides f. lusitanicus	33%	100%
P14963	Euglena gracilis	34%	100%
P15170	Homo sapiens	35%	100%
P17196	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	32%	100%
P17506	Xenopus laevis	35%	100%
P17507	Xenopus laevis	33%	100%
P17508	Xenopus laevis	33%	100%
P17786	Solanum lycopersicum	34%	100%
P19039	Apis mellifera	35%	100%
P23637	Ogataea pini	34%	87%
P23845	Escherichia coli (strain K12)	26%	100%
P25166	Stylonychia lemnae	33%	100%
P25698	Glycine max	34%	100%
P27592	Onchocerca volvulus	33%	100%
P28295	Absidia glauca	33%	100%
P28604	Azospirillum brasilense	28%	100%
P29520	Bombyx mori	35%	100%
P29521	Daucus carota	34%	100%
P32186	Puccinia graminis	32%	100%
P32769	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	29%	100%
P34823	Daucus carota	33%	100%
P34824	Hordeum vulgare	33%	100%
P34825	Hypocrea jecorina	33%	100%
P40911	Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)	33%	100%
P41203	Desulfurococcus mucosus	35%	100%
P41745	Blastobotrys adeninivorans	34%	100%
P41752	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	34%	100%
P43643	Nicotiana tabacum	34%	100%
P46280	Glycine max	26%	100%
P50256	Porphyra purpurea	36%	100%
P51554	Hydra vulgaris	32%	100%
P52978	Rhizobium tropici	26%	100%
P53013	Caenorhabditis elegans	33%	100%
P54959	Blastocystis hominis	35%	100%
P56893	Rhizobium meliloti (strain 1021)	27%	100%
P57498	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	24%	100%
P62629	Cricetulus griseus	34%	100%
P62630	Rattus norvegicus	34%	100%
P62631	Mus musculus	34%	100%
P62632	Rattus norvegicus	34%	100%
P68103	Bos taurus	34%	100%
P68104	Homo sapiens	34%	100%
P68105	Oryctolagus cuniculus	34%	100%
P68158	Nicotiana tabacum	27%	100%
P72339	Rhizobium sp. (strain N33)	26%	100%
P86933	Trypanosoma brucei brucei	35%	100%
P86934	Trypanosoma brucei brucei (strain 927/4 GUTat10.1)	36%	100%
P86939	Trypanosoma brucei brucei (strain 927/4 GUTat10.1)	36%	100%
P90519	Cryptosporidium parvum	35%	100%
P9WNM4	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	27%	100%
P9WNM5	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	27%	100%
Q00080	Plasmodium falciparum (isolate K1 / Thailand)	35%	100%
Q00251	Aureobasidium pullulans	34%	100%
Q01372	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	34%	100%
Q01520	Podospora anserina	33%	100%
Q01765	Podospora curvicolla	33%	100%
Q03033	Triticum aestivum	33%	100%
Q04634	Tetrahymena pyriformis	33%	100%
Q05639	Homo sapiens	34%	100%
Q09069	Sordaria macrospora	34%	100%
Q0T1I2	Shigella flexneri serotype 5b (strain 8401)	25%	100%
Q0TEA7	Escherichia coli O6:K15:H31 (strain 536 / UPEC)	26%	100%
Q0WL56	Arabidopsis thaliana	34%	100%
Q149F3	Mus musculus	35%	100%
Q14HG2	Francisella tularensis subsp. tularensis (strain FSC 198)	28%	100%
Q1R7U0	Escherichia coli (strain UTI89 / UPEC)	26%	100%
Q27139	Euplotes crassus	34%	100%
Q27140	Euplotes crassus	32%	100%
Q2HJN4	Oscheius tipulae	34%	100%
Q2HJN6	Oscheius tipulae	35%	100%
Q2HJN8	Oscheius tipulae	34%	100%
Q2HJN9	Oscheius tipulae	34%	100%
Q2KHZ2	Bos taurus	36%	94%
Q31XB3	Shigella boydii serotype 4 (strain Sb227)	25%	100%
Q32CH9	Shigella dysenteriae serotype 1 (strain Sd197)	25%	100%
Q32PH8	Bos taurus	34%	100%
Q3YYB1	Shigella sonnei (strain Ss046)	26%	100%
Q40034	Hordeum vulgare	33%	100%
Q40450	Nicotiana sylvestris	27%	100%
Q41011	Pisum sativum	34%	100%
Q41803	Zea mays	34%	100%
Q4QEI8	Leishmania major	34%	100%
Q4QEI9	Leishmania major	34%	100%
Q4QGW5	Leishmania major	30%	100%
Q57KJ0	Salmonella choleraesuis (strain SC-B67)	26%	100%
Q59QD6	Candida albicans (strain SC5314 / ATCC MYA-2876)	33%	100%
Q5LES3	Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow)	28%	100%
Q5NG10	Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)	28%	100%
Q5PEH2	Salmonella paratyphi A (strain ATCC 9150 / SARB42)	26%	100%
Q5R1X2	Pan troglodytes	34%	100%
Q5R4B3	Pongo abelii	35%	100%
Q5R4R8	Pongo abelii	34%	100%
Q5R6Y0	Pongo abelii	35%	94%
Q5VTE0	Homo sapiens	34%	100%
Q64VQ9	Bacteroides fragilis (strain YCH46)	28%	100%
Q66EC7	Yersinia pseudotuberculosis serotype I (strain IP32953)	26%	100%
Q66RN5	Felis catus	34%	100%
Q69ZS7	Mus musculus	36%	95%
Q6AXM7	Rattus norvegicus	37%	95%
Q71V39	Oryctolagus cuniculus	34%	100%
Q74MI6	Nanoarchaeum equitans (strain Kin4-M)	32%	100%
Q7MPF2	Vibrio vulnificus (strain YJ016)	25%	100%
Q7NVN5	Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)	27%	100%
Q7UMW2	Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)	25%	100%
Q7YZN9	Dictyostelium discoideum	31%	100%
Q83JX8	Shigella flexneri	25%	100%
Q87DG7	Xylella fastidiosa (strain Temecula1 / ATCC 700964)	27%	100%
Q8DE73	Vibrio vulnificus (strain CMCP6)	25%	100%
Q8FEJ1	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	26%	100%
Q8GTY0	Arabidopsis thaliana	34%	100%
Q8IYD1	Homo sapiens	35%	100%
Q8LPC4	Neopyropia yezoensis	37%	100%
Q8R050	Mus musculus	35%	100%
Q8UH69	Agrobacterium fabrum (strain C58 / ATCC 33970)	26%	100%
Q8W4H7	Arabidopsis thaliana	34%	100%
Q8X7X7	Escherichia coli O157:H7	26%	100%
Q8Z470	Salmonella typhi	25%	100%
Q8ZBP2	Yersinia pestis	26%	100%
Q8ZMF5	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	26%	100%
Q90835	Gallus gallus	34%	100%
Q92005	Danio rerio	33%	100%
Q95VF2	Leishmania donovani	34%	100%
Q96WZ1	Coccidioides immitis (strain RS)	34%	100%
Q9HDF6	Serendipita indica	33%	100%
Q9HGI4	Zygosaccharomyces rouxii	34%	98%
Q9HGI6	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	33%	92%
Q9HGI7	Candida maltosa	35%	91%
Q9HGI8	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	33%	92%
Q9PD78	Xylella fastidiosa (strain 9a5c)	27%	100%
Q9W074	Drosophila melanogaster	32%	96%
Q9Y450	Homo sapiens	36%	94%
Q9Y713	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	33%	100%
Q9YAV0	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	37%	100%
Q9YIC0	Oryzias latipes	34%	100%
V5BT94	Trypanosoma cruzi	55%	97%
V5BWI6	Trypanosoma cruzi	32%	100%
V5DGZ5	Trypanosoma cruzi	36%	90%