Ribosomal protein S17 family protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

30S Ribosomal protein S17-like protein

Species:

Leishmania donovani

UniProt:

A0A3S7X9P6_LEIDO

TriTrypDb:

LdBPK_353890.1 , LdCL_350044000 , LDHU3_35.5060

Length:

312

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005840	ribosome	5	12
GO:0043226	organelle	2	12
GO:0043228	non-membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043232	intracellular non-membrane-bounded organelle	4	12
GO:0110165	cellular anatomical entity	1	12
GO:0005739	mitochondrion	5	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1

Expansion

Sequence features

A0A3S7X9P6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X9P6

PDB structure(s): 7ane_k

Function

Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	12
GO:0006518	peptide metabolic process	4	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009058	biosynthetic process	2	12
GO:0009059	macromolecule biosynthetic process	4	12
GO:0009987	cellular process	1	12
GO:0019538	protein metabolic process	3	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	12
GO:0043043	peptide biosynthetic process	5	12
GO:0043170	macromolecule metabolic process	3	12
GO:0043603	amide metabolic process	3	12
GO:0043604	amide biosynthetic process	4	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044249	cellular biosynthetic process	3	12
GO:0044260	obsolete cellular macromolecule metabolic process	3	12
GO:0044271	cellular nitrogen compound biosynthetic process	4	12
GO:0071704	organic substance metabolic process	2	12
GO:1901564	organonitrogen compound metabolic process	3	12
GO:1901566	organonitrogen compound biosynthetic process	4	12
GO:1901576	organic substance biosynthetic process	3	12

Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	12
GO:0005198	structural molecule activity	1	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	150	152	PF00675	0.274
CLV_NRD_NRD_1	193	195	PF00675	0.466
CLV_NRD_NRD_1	43	45	PF00675	0.596
CLV_NRD_NRD_1	72	74	PF00675	0.446
CLV_PCSK_FUR_1	70	74	PF00082	0.450
CLV_PCSK_KEX2_1	193	195	PF00082	0.466
CLV_PCSK_KEX2_1	47	49	PF00082	0.498
CLV_PCSK_KEX2_1	72	74	PF00082	0.446
CLV_PCSK_PC1ET2_1	47	49	PF00082	0.498
CLV_PCSK_SKI1_1	194	198	PF00082	0.463
CLV_PCSK_SKI1_1	306	310	PF00082	0.596
CLV_PCSK_SKI1_1	44	48	PF00082	0.496
DEG_APCC_DBOX_1	2	10	PF00400	0.577
DEG_Nend_Nbox_1	1	3	PF02207	0.563
DOC_MAPK_FxFP_2	187	190	PF00069	0.472
DOC_MAPK_gen_1	172	179	PF00069	0.446
DOC_MAPK_gen_1	193	200	PF00069	0.469
DOC_MAPK_MEF2A_6	172	179	PF00069	0.446
DOC_MAPK_MEF2A_6	193	200	PF00069	0.469
DOC_MAPK_NFAT4_5	172	180	PF00069	0.447
DOC_PP2B_LxvP_1	7	10	PF13499	0.602
DOC_PP4_FxxP_1	187	190	PF00568	0.456
DOC_PP4_FxxP_1	224	227	PF00568	0.502
DOC_PP4_FxxP_1	85	88	PF00568	0.427
DOC_USP7_MATH_1	251	255	PF00917	0.727
DOC_USP7_UBL2_3	148	152	PF12436	0.476
DOC_USP7_UBL2_3	176	180	PF12436	0.478
DOC_USP7_UBL2_3	302	306	PF12436	0.574
DOC_WW_Pin1_4	225	230	PF00397	0.530
LIG_14-3-3_CanoR_1	123	131	PF00244	0.487
LIG_14-3-3_CanoR_1	233	242	PF00244	0.610
LIG_14-3-3_CanoR_1	3	7	PF00244	0.533
LIG_Actin_WH2_2	91	107	PF00022	0.344
LIG_BRCT_BRCA1_1	127	131	PF00533	0.487
LIG_BRCT_BRCA1_1	238	242	PF00533	0.592
LIG_BRCT_BRCA1_1	81	85	PF00533	0.422
LIG_EVH1_2	183	187	PF00568	0.451
LIG_FHA_1	254	260	PF00498	0.688
LIG_FHA_1	79	85	PF00498	0.509
LIG_FHA_1	99	105	PF00498	0.476
LIG_FHA_2	199	205	PF00498	0.485
LIG_LIR_Apic_2	82	88	PF02991	0.434
LIG_LIR_Gen_1	276	284	PF02991	0.635
LIG_LIR_Gen_1	291	299	PF02991	0.605
LIG_LIR_Nem_3	154	159	PF02991	0.476
LIG_LIR_Nem_3	276	281	PF02991	0.638
LIG_LIR_Nem_3	291	297	PF02991	0.612
LIG_LIR_Nem_3	304	308	PF02991	0.584
LIG_MLH1_MIPbox_1	127	131	PF16413	0.487
LIG_Rb_LxCxE_1	134	154	PF01857	0.487
LIG_SH2_STAT5	160	163	PF00017	0.524
LIG_SH2_STAT5	42	45	PF00017	0.553
LIG_SH2_STAT5	97	100	PF00017	0.466
LIG_SH3_3	112	118	PF00018	0.476
LIG_SH3_3	179	185	PF00018	0.435
LIG_SH3_3	226	232	PF00018	0.541
LIG_TRAF2_1	213	216	PF00917	0.522
LIG_TRAF2_1	261	264	PF00917	0.676
LIG_TRAF2_2	88	93	PF00917	0.415
MOD_CK1_1	125	131	PF00069	0.517
MOD_CK2_1	160	166	PF00069	0.530
MOD_CK2_1	198	204	PF00069	0.476
MOD_CK2_1	238	244	PF00069	0.698
MOD_CK2_1	276	282	PF00069	0.655
MOD_GlcNHglycan	238	241	PF01048	0.611
MOD_GSK3_1	147	154	PF00069	0.562
MOD_GSK3_1	234	241	PF00069	0.599
MOD_GSK3_1	99	106	PF00069	0.480
MOD_N-GLC_1	198	203	PF02516	0.474
MOD_N-GLC_1	251	256	PF02516	0.731
MOD_N-GLC_1	52	57	PF02516	0.459
MOD_NEK2_1	103	108	PF00069	0.470
MOD_NEK2_1	198	203	PF00069	0.486
MOD_NEK2_1	2	7	PF00069	0.537
MOD_NEK2_1	236	241	PF00069	0.599
MOD_PKA_1	151	157	PF00069	0.476
MOD_PKA_2	122	128	PF00069	0.479
MOD_PKA_2	2	8	PF00069	0.537
MOD_Plk_1	251	257	PF00069	0.714
MOD_Plk_1	78	84	PF00069	0.421
MOD_Plk_2-3	238	244	PF00069	0.551
MOD_Plk_2-3	276	282	PF00069	0.673
MOD_Plk_4	2	8	PF00069	0.642
MOD_Plk_4	263	269	PF00069	0.634
MOD_Plk_4	79	85	PF00069	0.418
MOD_Plk_4	99	105	PF00069	0.480
MOD_ProDKin_1	225	231	PF00069	0.535
MOD_SUMO_rev_2	300	308	PF00179	0.600
TRG_DiLeu_BaEn_2	262	268	PF01217	0.743
TRG_DiLeu_BaEn_4	263	269	PF01217	0.731
TRG_ENDOCYTIC_2	117	120	PF00928	0.476
TRG_ENDOCYTIC_2	159	162	PF00928	0.476
TRG_ER_diArg_1	193	195	PF00400	0.466
TRG_ER_diArg_1	70	73	PF00400	0.453
TRG_ER_diLys_1	309	312	PF00400	0.610
TRG_NLS_MonoExtC_3	43	48	PF00514	0.476

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PA44	Leptomonas seymouri	93%	100%
A0A0S4J3Y6	Bodo saltans	74%	100%
A0A1X0P553	Trypanosomatidae	84%	100%
A0A3R7K2G8	Trypanosoma rangeli	87%	100%
A4HN56	Leishmania braziliensis	96%	100%
A4IBS3	Leishmania infantum	100%	100%
C9ZYU9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	82%	100%
E9AFK9	Leishmania major	98%	100%
E9B6R3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
V5BTB8	Trypanosoma cruzi	85%	100%