LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7X9N6_LEIDO
TriTrypDb:
LdBPK_353760.1 * , LdCL_350042600 , LDHU3_35.4920
Length:
341

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 10
GO:0110165 cellular anatomical entity 1 10
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Expansion

Sequence features

A0A3S7X9N6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X9N6

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 56 60 PF00656 0.487
CLV_NRD_NRD_1 129 131 PF00675 0.572
CLV_NRD_NRD_1 77 79 PF00675 0.677
CLV_PCSK_FUR_1 75 79 PF00082 0.613
CLV_PCSK_KEX2_1 129 131 PF00082 0.568
CLV_PCSK_KEX2_1 77 79 PF00082 0.714
CLV_PCSK_SKI1_1 117 121 PF00082 0.663
CLV_PCSK_SKI1_1 274 278 PF00082 0.568
CLV_PCSK_SKI1_1 282 286 PF00082 0.355
DEG_MDM2_SWIB_1 235 243 PF02201 0.575
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PB50 Leptomonas seymouri 58% 99%
A0A1X0P6A1 Trypanosomatidae 41% 100%
A0A422MTB0 Trypanosoma rangeli 40% 100%
A4HN42 Leishmania braziliensis 86% 100%
A4IBR0 Leishmania infantum 99% 100%
C9ZYW4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 39% 100%
E9AFJ5 Leishmania major 99% 100%
E9B6P9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 94% 100%
V5C2T1 Trypanosoma cruzi 42% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS