Class I transcription factor A, subunit 2, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

class I transcription factor A, subunit 2, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X9K7_LEIDO

TriTrypDb:

LdBPK_353200.1 , LdCL_350036900 , LDHU3_35.4190

Length:

514

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X9K7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X9K7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	402	406	PF00656	0.739
CLV_NRD_NRD_1	143	145	PF00675	0.567
CLV_NRD_NRD_1	223	225	PF00675	0.532
CLV_NRD_NRD_1	246	248	PF00675	0.417
CLV_NRD_NRD_1	292	294	PF00675	0.541
CLV_NRD_NRD_1	313	315	PF00675	0.531
CLV_NRD_NRD_1	372	374	PF00675	0.614
CLV_NRD_NRD_1	433	435	PF00675	0.672
CLV_NRD_NRD_1	483	485	PF00675	0.566
CLV_NRD_NRD_1	493	495	PF00675	0.518
CLV_NRD_NRD_1	91	93	PF00675	0.678
CLV_PCSK_KEX2_1	143	145	PF00082	0.567
CLV_PCSK_KEX2_1	223	225	PF00082	0.447
CLV_PCSK_KEX2_1	246	248	PF00082	0.432
CLV_PCSK_KEX2_1	313	315	PF00082	0.511
CLV_PCSK_KEX2_1	34	36	PF00082	0.523
CLV_PCSK_KEX2_1	359	361	PF00082	0.643
CLV_PCSK_KEX2_1	433	435	PF00082	0.672
CLV_PCSK_KEX2_1	482	484	PF00082	0.627
CLV_PCSK_KEX2_1	493	495	PF00082	0.516
CLV_PCSK_KEX2_1	91	93	PF00082	0.655
CLV_PCSK_PC1ET2_1	34	36	PF00082	0.523
CLV_PCSK_PC1ET2_1	359	361	PF00082	0.643
CLV_PCSK_PC7_1	355	361	PF00082	0.644
CLV_PCSK_PC7_1	489	495	PF00082	0.622
CLV_PCSK_SKI1_1	115	119	PF00082	0.508
CLV_PCSK_SKI1_1	134	138	PF00082	0.551
CLV_PCSK_SKI1_1	267	271	PF00082	0.519
CLV_PCSK_SKI1_1	313	317	PF00082	0.577
CLV_PCSK_SKI1_1	493	497	PF00082	0.559
CLV_PCSK_SKI1_1	86	90	PF00082	0.678
DEG_APCC_DBOX_1	226	234	PF00400	0.537
DEG_APCC_DBOX_1	376	384	PF00400	0.526
DEG_SPOP_SBC_1	420	424	PF00917	0.608
DOC_CKS1_1	268	273	PF01111	0.484
DOC_CYCLIN_RxL_1	215	226	PF00134	0.436
DOC_MAPK_gen_1	313	321	PF00069	0.581
DOC_MAPK_gen_1	373	383	PF00069	0.635
DOC_MAPK_MEF2A_6	465	474	PF00069	0.575
DOC_PP1_RVXF_1	216	223	PF00149	0.487
DOC_PP1_RVXF_1	84	91	PF00149	0.555
DOC_PP2B_LxvP_1	13	16	PF13499	0.480
DOC_PP2B_LxvP_1	472	475	PF13499	0.607
DOC_USP7_MATH_1	166	170	PF00917	0.675
DOC_USP7_MATH_1	364	368	PF00917	0.722
DOC_USP7_MATH_1	54	58	PF00917	0.733
DOC_USP7_MATH_1	62	66	PF00917	0.478
DOC_WW_Pin1_4	267	272	PF00397	0.553
DOC_WW_Pin1_4	282	287	PF00397	0.573
DOC_WW_Pin1_4	414	419	PF00397	0.620
DOC_WW_Pin1_4	97	102	PF00397	0.442
LIG_14-3-3_CanoR_1	115	125	PF00244	0.428
LIG_14-3-3_CanoR_1	128	132	PF00244	0.339
LIG_14-3-3_CanoR_1	181	191	PF00244	0.609
LIG_14-3-3_CanoR_1	234	244	PF00244	0.521
LIG_14-3-3_CanoR_1	291	299	PF00244	0.506
LIG_14-3-3_CanoR_1	313	321	PF00244	0.584
LIG_14-3-3_CanoR_1	362	372	PF00244	0.720
LIG_14-3-3_CanoR_1	506	511	PF00244	0.593
LIG_deltaCOP1_diTrp_1	432	442	PF00928	0.659
LIG_FHA_1	165	171	PF00498	0.618
LIG_FHA_1	314	320	PF00498	0.590
LIG_FHA_1	415	421	PF00498	0.629
LIG_FHA_1	424	430	PF00498	0.581
LIG_FHA_1	443	449	PF00498	0.456
LIG_FHA_1	79	85	PF00498	0.543
LIG_FHA_2	163	169	PF00498	0.673
LIG_FHA_2	208	214	PF00498	0.514
LIG_FHA_2	321	327	PF00498	0.553
LIG_GBD_Chelix_1	104	112	PF00786	0.501
LIG_LIR_Gen_1	256	265	PF02991	0.514
LIG_LIR_Nem_3	130	136	PF02991	0.538
LIG_LIR_Nem_3	219	225	PF02991	0.373
LIG_LIR_Nem_3	256	262	PF02991	0.511
LIG_NRBOX	379	385	PF00104	0.531
LIG_Pex14_2	259	263	PF04695	0.504
LIG_RPA_C_Fungi	213	225	PF08784	0.403
LIG_SH2_CRK	245	249	PF00017	0.429
LIG_SH2_CRK	468	472	PF00017	0.604
LIG_SH2_CRK	492	496	PF00017	0.639
LIG_SH3_2	16	21	PF14604	0.543
LIG_SH3_3	13	19	PF00018	0.578
LIG_SH3_3	91	97	PF00018	0.485
LIG_SUMO_SIM_par_1	247	253	PF11976	0.494
LIG_SUMO_SIM_par_1	326	334	PF11976	0.550
LIG_SxIP_EBH_1	52	66	PF03271	0.542
LIG_TYR_ITIM	243	248	PF00017	0.433
MOD_CK1_1	169	175	PF00069	0.656
MOD_CK1_1	187	193	PF00069	0.648
MOD_CK1_1	320	326	PF00069	0.567
MOD_CK1_1	423	429	PF00069	0.619
MOD_CK1_1	443	449	PF00069	0.449
MOD_CK2_1	162	168	PF00069	0.531
MOD_CK2_1	207	213	PF00069	0.499
MOD_CK2_1	235	241	PF00069	0.587
MOD_CK2_1	421	427	PF00069	0.654
MOD_CK2_1	62	68	PF00069	0.685
MOD_GlcNHglycan	276	279	PF01048	0.453
MOD_GlcNHglycan	355	358	PF01048	0.666
MOD_GlcNHglycan	366	369	PF01048	0.554
MOD_GlcNHglycan	423	426	PF01048	0.688
MOD_GlcNHglycan	437	440	PF01048	0.586
MOD_GlcNHglycan	442	445	PF01048	0.556
MOD_GSK3_1	162	169	PF00069	0.546
MOD_GSK3_1	183	190	PF00069	0.681
MOD_GSK3_1	263	270	PF00069	0.533
MOD_GSK3_1	313	320	PF00069	0.586
MOD_GSK3_1	360	367	PF00069	0.702
MOD_GSK3_1	416	423	PF00069	0.608
MOD_LATS_1	132	138	PF00433	0.386
MOD_N-GLC_1	317	322	PF02516	0.679
MOD_NEK2_1	136	141	PF00069	0.544
MOD_NEK2_1	182	187	PF00069	0.753
MOD_NEK2_1	202	207	PF00069	0.491
MOD_NEK2_1	263	268	PF00069	0.461
MOD_NEK2_1	274	279	PF00069	0.545
MOD_NEK2_1	442	447	PF00069	0.781
MOD_NEK2_1	448	453	PF00069	0.657
MOD_NEK2_1	55	60	PF00069	0.532
MOD_PIKK_1	134	140	PF00454	0.459
MOD_PIKK_1	169	175	PF00454	0.656
MOD_PIKK_1	184	190	PF00454	0.529
MOD_PIKK_1	297	303	PF00454	0.501
MOD_PIKK_1	3	9	PF00454	0.548
MOD_PIKK_1	443	449	PF00454	0.596
MOD_PK_1	236	242	PF00069	0.543
MOD_PKA_1	223	229	PF00069	0.538
MOD_PKA_1	313	319	PF00069	0.586
MOD_PKA_1	483	489	PF00069	0.579
MOD_PKA_2	127	133	PF00069	0.596
MOD_PKA_2	223	229	PF00069	0.538
MOD_PKA_2	235	241	PF00069	0.602
MOD_PKA_2	292	298	PF00069	0.517
MOD_PKA_2	313	319	PF00069	0.586
MOD_PKA_2	483	489	PF00069	0.572
MOD_PKA_2	78	84	PF00069	0.537
MOD_PKB_1	234	242	PF00069	0.544
MOD_Plk_1	177	183	PF00069	0.543
MOD_Plk_1	317	323	PF00069	0.680
MOD_Plk_4	166	172	PF00069	0.668
MOD_Plk_4	202	208	PF00069	0.553
MOD_Plk_4	416	422	PF00069	0.616
MOD_ProDKin_1	267	273	PF00069	0.556
MOD_ProDKin_1	282	288	PF00069	0.577
MOD_ProDKin_1	414	420	PF00069	0.622
MOD_ProDKin_1	97	103	PF00069	0.445
MOD_SUMO_rev_2	277	286	PF00179	0.492
TRG_DiLeu_BaLyEn_6	467	472	PF01217	0.608
TRG_DiLeu_BaLyEn_6	491	496	PF01217	0.546
TRG_ENDOCYTIC_2	245	248	PF00928	0.584
TRG_ENDOCYTIC_2	468	471	PF00928	0.604
TRG_ENDOCYTIC_2	492	495	PF00928	0.644
TRG_ER_diArg_1	112	115	PF00400	0.435
TRG_ER_diArg_1	222	224	PF00400	0.516
TRG_ER_diArg_1	233	236	PF00400	0.493
TRG_ER_diArg_1	245	247	PF00400	0.380
TRG_ER_diArg_1	312	314	PF00400	0.528
TRG_ER_diArg_1	377	380	PF00400	0.664
TRG_ER_diArg_1	433	435	PF00400	0.664
TRG_ER_diArg_1	482	484	PF00400	0.684
TRG_ER_diArg_1	492	494	PF00400	0.527
TRG_ER_diArg_1	90	92	PF00400	0.719

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5S0	Leptomonas seymouri	41%	98%
A0A1X0P6U1	Trypanosomatidae	24%	100%
A0A3R7MGU2	Trypanosoma rangeli	28%	100%
A4HMY2	Leishmania braziliensis	72%	99%
A4IBK6	Leishmania infantum	100%	100%
E9AFD9	Leishmania major	93%	100%
E9B6J4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
V5C2W6	Trypanosoma cruzi	26%	100%