LeishMANIAdb
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Yos1-like_putative/Pfam:PF08571

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Yos1-like_putative/Pfam:PF08571
Gene product:
Yos1-like, putative
Species:
Leishmania donovani
UniProt:
A0A3S7X9K4_LEIDO
TriTrypDb:
LdBPK_352550.1 , LdCL_350030400 , LDHU3_35.3300
Length:
111

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 9
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Cellular components
TermNameLevelCount
GO:0005789 endoplasmic reticulum membrane 4 1
GO:0016020 membrane 2 9
GO:0030134 COPII-coated ER to Golgi transport vesicle 8 1
GO:0030135 coated vesicle 7 1
GO:0031090 organelle membrane 3 1
GO:0031410 cytoplasmic vesicle 6 1
GO:0031982 vesicle 4 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
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Expansion

Sequence features

A0A3S7X9K4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X9K4

Function

Biological processes
TermNameLevelCount
GO:0006810 transport 3 9
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 4 1
GO:0008104 protein localization 4 9
GO:0009987 cellular process 1 9
GO:0015031 protein transport 4 9
GO:0016192 vesicle-mediated transport 4 1
GO:0033036 macromolecule localization 2 9
GO:0045184 establishment of protein localization 3 9
GO:0046907 intracellular transport 3 1
GO:0048193 Golgi vesicle transport 5 1
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Could not find GO molecular_function term for this entry.

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
DEG_APCC_DBOX_1 92 100 PF00400 0.357
DOC_CKS1_1 33 38 PF01111 0.492
DOC_MAPK_MEF2A_6 72 81 PF00069 0.498
DOC_MAPK_MEF2A_6 93 101 PF00069 0.399
DOC_PP2B_PxIxI_1 94 100 PF00149 0.357
DOC_WW_Pin1_4 32 37 PF00397 0.486
LIG_14-3-3_CanoR_1 72 78 PF00244 0.457
LIG_EH1_1 85 93 PF00400 0.492
LIG_LIR_Gen_1 4 14 PF02991 0.492
LIG_LIR_Gen_1 48 59 PF02991 0.492
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Homologs

ProteinTaxonomySequence identityCoverage
A0A1X0P5S0 Trypanosomatidae 49% 100%
A0A3R7KCE1 Trypanosoma rangeli 48% 100%
A4IBG0 Leishmania infantum 99% 100%
C9ZZA4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 41% 100%
E9AF74 Leishmania major 94% 100%
E9AIW2 Leishmania braziliensis 85% 100%
E9B6D0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 94% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS