LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Transporter-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Transporter-like protein
Gene product:
transporter-like protein
Species:
Leishmania donovani
UniProt:
A0A3S7X9E2_LEIDO
TriTrypDb:
LdBPK_352830.1 * , LdCL_350033200 , LDHU3_35.3610
Length:
698

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 12
NetGPI no yes: 0, no: 12
Cellular components
Term Name Level Count
GO:0016020 membrane 2 13
GO:0110165 cellular anatomical entity 1 13

Expansion

Sequence features

A0A3S7X9E2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X9E2

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0005215 transporter activity 1 13
GO:0022857 transmembrane transporter activity 2 13

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 525 529 PF00656 0.672
CLV_C14_Caspase3-7 551 555 PF00656 0.653
CLV_NRD_NRD_1 105 107 PF00675 0.237
CLV_NRD_NRD_1 326 328 PF00675 0.354
CLV_NRD_NRD_1 433 435 PF00675 0.560
CLV_NRD_NRD_1 549 551 PF00675 0.550
CLV_PCSK_KEX2_1 326 328 PF00082 0.348
CLV_PCSK_KEX2_1 549 551 PF00082 0.550
CLV_PCSK_SKI1_1 196 200 PF00082 0.431
CLV_PCSK_SKI1_1 246 250 PF00082 0.402
CLV_PCSK_SKI1_1 317 321 PF00082 0.284
DEG_SCF_TRCP1_1 554 559 PF00400 0.772
DOC_CYCLIN_RxL_1 162 173 PF00134 0.502
DOC_MAPK_gen_1 103 112 PF00069 0.417
DOC_MAPK_gen_1 163 172 PF00069 0.517
DOC_MAPK_MEF2A_6 103 112 PF00069 0.429
DOC_MAPK_MEF2A_6 255 263 PF00069 0.585
DOC_PP1_RVXF_1 194 200 PF00149 0.168
DOC_PP1_RVXF_1 324 331 PF00149 0.435
DOC_PP2B_LxvP_1 451 454 PF13499 0.398
DOC_PP4_FxxP_1 320 323 PF00568 0.541
DOC_SPAK_OSR1_1 396 400 PF12202 0.385
DOC_USP7_MATH_1 144 148 PF00917 0.384
DOC_USP7_MATH_1 168 172 PF00917 0.318
DOC_USP7_MATH_1 351 355 PF00917 0.315
DOC_USP7_MATH_1 625 629 PF00917 0.747
DOC_USP7_UBL2_3 103 107 PF12436 0.428
DOC_WW_Pin1_4 191 196 PF00397 0.209
DOC_WW_Pin1_4 200 205 PF00397 0.197
DOC_WW_Pin1_4 29 34 PF00397 0.540
DOC_WW_Pin1_4 292 297 PF00397 0.774
DOC_WW_Pin1_4 359 364 PF00397 0.384
DOC_WW_Pin1_4 609 614 PF00397 0.653
DOC_WW_Pin1_4 692 697 PF00397 0.609
LIG_14-3-3_CanoR_1 423 429 PF00244 0.294
LIG_14-3-3_CanoR_1 561 567 PF00244 0.645
LIG_Actin_WH2_2 221 238 PF00022 0.330
LIG_Actin_WH2_2 249 264 PF00022 0.547
LIG_Actin_WH2_2 421 436 PF00022 0.339
LIG_BRCT_BRCA1_1 230 234 PF00533 0.326
LIG_BRCT_BRCA1_1 438 442 PF00533 0.295
LIG_deltaCOP1_diTrp_1 438 442 PF00928 0.382
LIG_EH1_1 250 258 PF00400 0.436
LIG_EH1_1 363 371 PF00400 0.263
LIG_eIF4E_1 364 370 PF01652 0.150
LIG_FHA_1 171 177 PF00498 0.338
LIG_FHA_1 220 226 PF00498 0.303
LIG_FHA_1 407 413 PF00498 0.368
LIG_FHA_1 46 52 PF00498 0.282
LIG_FHA_1 466 472 PF00498 0.443
LIG_FHA_1 569 575 PF00498 0.717
LIG_FHA_1 585 591 PF00498 0.601
LIG_FHA_2 605 611 PF00498 0.740
LIG_FHA_2 652 658 PF00498 0.646
LIG_IRF3_LxIS_1 104 111 PF10401 0.385
LIG_LIR_Apic_2 318 323 PF02991 0.489
LIG_LIR_Gen_1 222 230 PF02991 0.262
LIG_LIR_Gen_1 339 350 PF02991 0.360
LIG_LIR_Gen_1 439 449 PF02991 0.270
LIG_LIR_Gen_1 50 61 PF02991 0.321
LIG_LIR_Gen_1 562 570 PF02991 0.725
LIG_LIR_Gen_1 579 590 PF02991 0.523
LIG_LIR_Gen_1 651 659 PF02991 0.680
LIG_LIR_Nem_3 222 226 PF02991 0.278
LIG_LIR_Nem_3 339 345 PF02991 0.318
LIG_LIR_Nem_3 439 445 PF02991 0.261
LIG_LIR_Nem_3 50 56 PF02991 0.420
LIG_LIR_Nem_3 562 567 PF02991 0.673
LIG_LIR_Nem_3 579 585 PF02991 0.544
LIG_LIR_Nem_3 62 66 PF02991 0.316
LIG_LIR_Nem_3 651 655 PF02991 0.685
LIG_LYPXL_SIV_4 363 371 PF13949 0.150
LIG_NRBOX 138 144 PF00104 0.273
LIG_NRBOX 499 505 PF00104 0.398
LIG_Pex14_1 131 135 PF04695 0.323
LIG_Pex14_1 36 40 PF04695 0.428
LIG_Pex14_2 316 320 PF04695 0.515
LIG_Pex14_2 342 346 PF04695 0.394
LIG_Pex14_2 480 484 PF04695 0.375
LIG_Pex14_2 59 63 PF04695 0.293
LIG_PTB_Apo_2 378 385 PF02174 0.293
LIG_PTB_Apo_2 600 607 PF02174 0.633
LIG_SH2_CRK 652 656 PF00017 0.683
LIG_SH2_NCK_1 189 193 PF00017 0.260
LIG_SH2_SRC 520 523 PF00017 0.589
LIG_SH2_STAP1 582 586 PF00017 0.523
LIG_SH2_STAP1 652 656 PF00017 0.640
LIG_SH2_STAT5 499 502 PF00017 0.321
LIG_SH2_STAT5 514 517 PF00017 0.198
LIG_SH2_STAT5 520 523 PF00017 0.506
LIG_SH2_STAT5 66 69 PF00017 0.274
LIG_SH3_3 263 269 PF00018 0.623
LIG_SH3_3 304 310 PF00018 0.650
LIG_SH3_3 516 522 PF00018 0.382
LIG_SH3_3 52 58 PF00018 0.357
LIG_SH3_3 658 664 PF00018 0.736
LIG_Sin3_3 408 415 PF02671 0.249
LIG_SUMO_SIM_anti_2 274 280 PF11976 0.719
LIG_SUMO_SIM_par_1 168 173 PF11976 0.318
LIG_SUMO_SIM_par_1 43 50 PF11976 0.246
LIG_TRAF2_1 639 642 PF00917 0.757
LIG_WRC_WIRS_1 582 587 PF05994 0.527
LIG_WRC_WIRS_1 60 65 PF05994 0.323
MOD_CDK_SPK_2 191 196 PF00069 0.168
MOD_CDK_SPxxK_3 609 616 PF00069 0.593
MOD_CK1_1 155 161 PF00069 0.463
MOD_CK1_1 203 209 PF00069 0.349
MOD_CK1_1 22 28 PF00069 0.695
MOD_CK1_1 238 244 PF00069 0.532
MOD_CK1_1 559 565 PF00069 0.694
MOD_CK1_1 584 590 PF00069 0.654
MOD_CK1_1 609 615 PF00069 0.787
MOD_CK1_1 632 638 PF00069 0.734
MOD_CK1_1 9 15 PF00069 0.773
MOD_CK2_1 536 542 PF00069 0.661
MOD_CK2_1 604 610 PF00069 0.738
MOD_CK2_1 625 631 PF00069 0.767
MOD_CK2_1 636 642 PF00069 0.748
MOD_Cter_Amidation 104 107 PF01082 0.218
MOD_GlcNHglycan 126 129 PF01048 0.332
MOD_GlcNHglycan 14 17 PF01048 0.523
MOD_GlcNHglycan 20 24 PF01048 0.395
MOD_GlcNHglycan 240 243 PF01048 0.454
MOD_GlcNHglycan 296 299 PF01048 0.479
MOD_GlcNHglycan 390 393 PF01048 0.417
MOD_GlcNHglycan 488 491 PF01048 0.495
MOD_GlcNHglycan 544 547 PF01048 0.584
MOD_GlcNHglycan 550 553 PF01048 0.591
MOD_GlcNHglycan 554 557 PF01048 0.512
MOD_GlcNHglycan 597 600 PF01048 0.466
MOD_GlcNHglycan 73 77 PF01048 0.471
MOD_GlcNHglycan 78 81 PF01048 0.289
MOD_GlcNHglycan 92 95 PF01048 0.116
MOD_GSK3_1 413 420 PF00069 0.316
MOD_GSK3_1 47 54 PF00069 0.258
MOD_GSK3_1 5 12 PF00069 0.736
MOD_GSK3_1 548 555 PF00069 0.728
MOD_GSK3_1 562 569 PF00069 0.667
MOD_GSK3_1 576 583 PF00069 0.596
MOD_GSK3_1 621 628 PF00069 0.798
MOD_GSK3_1 632 639 PF00069 0.744
MOD_GSK3_1 690 697 PF00069 0.634
MOD_GSK3_1 72 79 PF00069 0.317
MOD_N-GLC_1 238 243 PF02516 0.438
MOD_N-GLC_1 637 642 PF02516 0.502
MOD_NEK2_1 108 113 PF00069 0.300
MOD_NEK2_1 126 131 PF00069 0.213
MOD_NEK2_1 157 162 PF00069 0.491
MOD_NEK2_1 235 240 PF00069 0.506
MOD_NEK2_1 418 423 PF00069 0.480
MOD_NEK2_1 424 429 PF00069 0.310
MOD_NEK2_1 447 452 PF00069 0.413
MOD_NEK2_1 47 52 PF00069 0.331
MOD_NEK2_1 484 489 PF00069 0.302
MOD_NEK2_1 502 507 PF00069 0.245
MOD_NEK2_1 566 571 PF00069 0.695
MOD_NEK2_1 580 585 PF00069 0.647
MOD_NEK2_2 175 180 PF00069 0.369
MOD_NEK2_2 556 561 PF00069 0.705
MOD_NEK2_2 625 630 PF00069 0.605
MOD_PIKK_1 398 404 PF00454 0.364
MOD_PIKK_1 637 643 PF00454 0.756
MOD_PIKK_1 9 15 PF00454 0.596
MOD_PKA_2 235 241 PF00069 0.605
MOD_PKA_2 548 554 PF00069 0.708
MOD_PKA_2 556 562 PF00069 0.661
MOD_PKA_2 576 582 PF00069 0.597
MOD_Plk_1 274 280 PF00069 0.680
MOD_Plk_2-3 651 657 PF00069 0.684
MOD_Plk_4 126 132 PF00069 0.314
MOD_Plk_4 144 150 PF00069 0.318
MOD_Plk_4 175 181 PF00069 0.271
MOD_Plk_4 203 209 PF00069 0.293
MOD_Plk_4 249 255 PF00069 0.440
MOD_Plk_4 274 280 PF00069 0.615
MOD_Plk_4 374 380 PF00069 0.337
MOD_Plk_4 383 389 PF00069 0.422
MOD_Plk_4 502 508 PF00069 0.287
MOD_Plk_4 562 568 PF00069 0.722
MOD_Plk_4 576 582 PF00069 0.660
MOD_Plk_4 59 65 PF00069 0.382
MOD_Plk_4 601 607 PF00069 0.640
MOD_Plk_4 651 657 PF00069 0.589
MOD_Plk_4 81 87 PF00069 0.257
MOD_ProDKin_1 191 197 PF00069 0.209
MOD_ProDKin_1 200 206 PF00069 0.197
MOD_ProDKin_1 29 35 PF00069 0.533
MOD_ProDKin_1 292 298 PF00069 0.771
MOD_ProDKin_1 359 365 PF00069 0.383
MOD_ProDKin_1 609 615 PF00069 0.654
MOD_ProDKin_1 692 698 PF00069 0.612
TRG_DiLeu_BaEn_1 576 581 PF01217 0.585
TRG_DiLeu_BaEn_1 651 656 PF01217 0.590
TRG_DiLeu_BaLyEn_6 320 325 PF01217 0.561
TRG_DiLeu_BaLyEn_6 661 666 PF01217 0.623
TRG_ENDOCYTIC_2 223 226 PF00928 0.331
TRG_ENDOCYTIC_2 405 408 PF00928 0.382
TRG_ENDOCYTIC_2 499 502 PF00928 0.353
TRG_ENDOCYTIC_2 564 567 PF00928 0.678
TRG_ENDOCYTIC_2 582 585 PF00928 0.473
TRG_ENDOCYTIC_2 652 655 PF00928 0.685
TRG_ER_diArg_1 325 327 PF00400 0.550
TRG_ER_diArg_1 560 563 PF00400 0.683
TRG_NES_CRM1_1 38 49 PF08389 0.443
TRG_Pf-PMV_PEXEL_1 243 247 PF00026 0.413
TRG_Pf-PMV_PEXEL_1 627 631 PF00026 0.423

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IBQ3 Leptomonas seymouri 37% 100%
A0A0N1PGE0 Leptomonas seymouri 56% 100%
A0A1X0P5R5 Trypanosomatidae 31% 100%
A0A286LF01 Psilocybe cyanescens 25% 100%
A0A3R7KR66 Trypanosoma rangeli 31% 100%
A4HMU4 Leishmania braziliensis 64% 100%
A4IBE5 Leishmania infantum 99% 100%
C9ZZ72 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
E9AFA2 Leishmania major 88% 100%
E9B6F7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 86% 100%
P0DPB2 Psilocybe cubensis 25% 100%
V5BTI8 Trypanosoma cruzi 36% 100%
V5C2Z8 Trypanosoma cruzi 31% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS