DUF4806 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Eukaryotic protein of unknown function (DUF1764), putative

Species:

Leishmania donovani

UniProt:

A0A3S7X9A2_LEIDO

TriTrypDb:

LdBPK_352410.1 , LdCL_350029000

Length:

199

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X9A2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X9A2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	162	164	PF00675	0.623
CLV_NRD_NRD_1	18	20	PF00675	0.520
CLV_PCSK_KEX2_1	162	164	PF00082	0.643
CLV_PCSK_KEX2_1	85	87	PF00082	0.633
CLV_PCSK_PC1ET2_1	85	87	PF00082	0.633
DEG_Nend_UBRbox_1	1	4	PF02207	0.679
DEG_SPOP_SBC_1	142	146	PF00917	0.634
DEG_SPOP_SBC_1	95	99	PF00917	0.660
DOC_USP7_MATH_1	115	119	PF00917	0.617
DOC_USP7_MATH_1	142	146	PF00917	0.656
DOC_USP7_MATH_1	147	151	PF00917	0.630
DOC_USP7_MATH_1	15	19	PF00917	0.685
DOC_USP7_MATH_1	154	158	PF00917	0.556
DOC_USP7_MATH_1	34	38	PF00917	0.697
DOC_USP7_MATH_1	7	11	PF00917	0.784
DOC_WW_Pin1_4	11	16	PF00397	0.673
DOC_WW_Pin1_4	150	155	PF00397	0.683
DOC_WW_Pin1_4	185	190	PF00397	0.305
DOC_WW_Pin1_4	32	37	PF00397	0.658
DOC_WW_Pin1_4	96	101	PF00397	0.616
LIG_14-3-3_CanoR_1	8	15	PF00244	0.688
LIG_14-3-3_CanoR_1	86	94	PF00244	0.672
LIG_FHA_1	12	18	PF00498	0.715
LIG_FHA_1	23	29	PF00498	0.690
LIG_FHA_1	36	42	PF00498	0.579
LIG_LIR_Apic_2	109	115	PF02991	0.575
LIG_LIR_Gen_1	46	56	PF02991	0.600
LIG_LIR_Nem_3	46	51	PF02991	0.504
LIG_Pex14_2	127	131	PF04695	0.604
LIG_SH3_3	186	192	PF00018	0.305
LIG_SUMO_SIM_par_1	168	174	PF11976	0.270
LIG_TRAF2_1	171	174	PF00917	0.308
LIG_UBA3_1	47	55	PF00899	0.537
MOD_CK1_1	150	156	PF00069	0.663
MOD_CK1_1	32	38	PF00069	0.691
MOD_CK2_1	168	174	PF00069	0.305
MOD_GlcNHglycan	127	130	PF01048	0.599
MOD_GlcNHglycan	145	148	PF01048	0.703
MOD_GlcNHglycan	9	12	PF01048	0.693
MOD_GSK3_1	115	122	PF00069	0.548
MOD_GSK3_1	134	141	PF00069	0.681
MOD_GSK3_1	143	150	PF00069	0.642
MOD_GSK3_1	173	180	PF00069	0.364
MOD_GSK3_1	30	37	PF00069	0.654
MOD_GSK3_1	43	50	PF00069	0.448
MOD_GSK3_1	7	14	PF00069	0.699
MOD_NEK2_1	127	132	PF00069	0.624
MOD_NEK2_1	47	52	PF00069	0.658
MOD_PK_1	168	174	PF00069	0.229
MOD_PKA_1	85	91	PF00069	0.773
MOD_PKA_2	7	13	PF00069	0.713
MOD_PKA_2	85	91	PF00069	0.670
MOD_Plk_1	115	121	PF00069	0.610
MOD_Plk_1	134	140	PF00069	0.627
MOD_Plk_4	127	133	PF00069	0.631
MOD_Plk_4	43	49	PF00069	0.628
MOD_ProDKin_1	11	17	PF00069	0.675
MOD_ProDKin_1	150	156	PF00069	0.683
MOD_ProDKin_1	185	191	PF00069	0.305
MOD_ProDKin_1	32	38	PF00069	0.654
MOD_ProDKin_1	96	102	PF00069	0.613
TRG_ER_diArg_1	161	163	PF00400	0.587

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I8J3	Leptomonas seymouri	49%	100%
A0A1X0P736	Trypanosomatidae	35%	100%
A4HMR0	Leishmania braziliensis	70%	99%
E9AF60	Leishmania major	86%	100%
E9AHW2	Leishmania infantum	99%	100%
E9B6B6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%